Generated Code

The following is c_ida code generated by the CellML API from this CellML file. (Back to language selection)

The raw code is available.

/*
   There are a total of 3 entries in the algebraic variable array.
   There are a total of 9 entries in each of the rate and state variable arrays.
   There are a total of 18 entries in the constant variable array.
 */
/*
 * VOI is time in component environment (second).
 * CONSTANTS[0] is EGF in component EGF (dimensionless).
 * CONSTANTS[1] is pro_EGFR in component pro_EGFR (dimensionless).
 * STATES[0] is EGFR in component EGFR (dimensionless).
 * STATES[1] is EGF_EGFR in component EGF_EGFR (dimensionless).
 * CONSTANTS[2] is k2_EGF_EGFR in component model_parameters (first_order_rate_constant).
 * CONSTANTS[3] is k1_EGF_EGFR in component model_parameters (first_order_rate_constant).
 * CONSTANTS[4] is EGFR_turnover in component model_parameters (first_order_rate_constant).
 * CONSTANTS[5] is k1_EGFR_phosphorylation in component model_parameters (first_order_rate_constant).
 * STATES[2] is pEGFR in component pEGFR (dimensionless).
 * STATES[3] is pEGFR_Akt in component pEGFR_Akt (dimensionless).
 * STATES[4] is Akt in component Akt (dimensionless).
 * CONSTANTS[6] is k1_pEGFR_degradation in component model_parameters (first_order_rate_constant).
 * CONSTANTS[7] is k1_Akt_phosphorylation in component model_parameters (first_order_rate_constant).
 * CONSTANTS[8] is k1_pEGFR_Akt in component model_parameters (first_order_rate_constant).
 * CONSTANTS[9] is k2_pEGFR_Akt in component model_parameters (first_order_rate_constant).
 * STATES[5] is pAkt in component pAkt (dimensionless).
 * CONSTANTS[10] is k1_pAkt_dephosphorylation in component model_parameters (first_order_rate_constant).
 * STATES[6] is S6 in component S6 (dimensionless).
 * STATES[7] is pAkt_S6 in component pAkt_S6 (dimensionless).
 * CONSTANTS[11] is k1_pAkt_S6 in component model_parameters (first_order_rate_constant).
 * CONSTANTS[12] is k2_pAkt_S6 in component model_parameters (first_order_rate_constant).
 * CONSTANTS[13] is k1_S6_phosphorylation in component model_parameters (first_order_rate_constant).
 * STATES[8] is pS6 in component pS6 (dimensionless).
 * CONSTANTS[14] is k1_pS6_dephosphorylation in component model_parameters (first_order_rate_constant).
 * ALGEBRAIC[0] is pEGFR_total in component pEGFR_total (dimensionless).
 * CONSTANTS[15] is pEGFR_scalefactor in component pEGFR_total (dimensionless).
 * ALGEBRAIC[1] is pAkt_total in component pAkt_total (dimensionless).
 * CONSTANTS[16] is pAkt_scalefactor in component pAkt_total (dimensionless).
 * ALGEBRAIC[2] is pS6_total in component pS6_total (dimensionless).
 * CONSTANTS[17] is pS6_scalefactor in component pS6_total (dimensionless).
 * RATES[0] is d/dt EGFR in component EGFR (dimensionless).
 * RATES[1] is d/dt EGF_EGFR in component EGF_EGFR (dimensionless).
 * RATES[2] is d/dt pEGFR in component pEGFR (dimensionless).
 * RATES[3] is d/dt pEGFR_Akt in component pEGFR_Akt (dimensionless).
 * RATES[4] is d/dt Akt in component Akt (dimensionless).
 * RATES[5] is d/dt pAkt in component pAkt (dimensionless).
 * RATES[7] is d/dt pAkt_S6 in component pAkt_S6 (dimensionless).
 * RATES[6] is d/dt S6 in component S6 (dimensionless).
 * RATES[8] is d/dt pS6 in component pS6 (dimensionless).
 * There are a total of 0 condition variables.
 */
void
initConsts(double* CONSTANTS, double* RATES, double *STATES)
{
CONSTANTS[0] = 30.0;
CONSTANTS[1] = 6.81902e4;
STATES[0] = 6.81902e4;
STATES[1] = 0.0;
CONSTANTS[2] = 4.07490e-2;
CONSTANTS[3] = 6.73816e-3;
CONSTANTS[4] = 1.06386129269658e-4;
CONSTANTS[5] = 1.92391e-2;
STATES[2] = 0.0;
STATES[3] = 0.0;
STATES[4] = 4.33090e-2;
CONSTANTS[6] = 9.97194e-2;
CONSTANTS[7] = 3.05684e-2;
CONSTANTS[8] = 1.55430e-5;
CONSTANTS[9] = 5.17473e-3;
STATES[5] = 0.0;
CONSTANTS[10] = 3.27962e-2;
STATES[6] = 3.54317e0;
STATES[7] = 0.0;
CONSTANTS[11] = 2.10189e-6;
CONSTANTS[12] = 5.17940e-15;
CONSTANTS[13] = 1.21498e-3;
STATES[8] = 0.0;
CONSTANTS[14] = 1.13102e-3;
CONSTANTS[15] = 1.81735e-4;
CONSTANTS[16] = 6.00588e1;
CONSTANTS[17] = 4.98862e4;
RATES[0] = 0.1001;
RATES[1] = 0.1001;
RATES[2] = 0.1001;
RATES[3] = 0.1001;
RATES[4] = 0.1001;
RATES[5] = 0.1001;
RATES[7] = 0.1001;
RATES[6] = 0.1001;
RATES[8] = 0.1001;
}
void
computeResiduals(double VOI, double* CONSTANTS, double* RATES, double* OLDRATES, double* STATES,
                 double* OLDSTATES, double* ALGEBRAIC, double* CONDVARS)
{
resid[0] = RATES[0] - ( CONSTANTS[2]*STATES[1]+ CONSTANTS[4]*(CONSTANTS[1] - STATES[0])) -  CONSTANTS[3]*CONSTANTS[0]*STATES[0];
resid[1] = RATES[1] -  CONSTANTS[3]*CONSTANTS[0]*STATES[0] - ( CONSTANTS[2]*STATES[1]+ CONSTANTS[5]*STATES[1]);
resid[2] = RATES[2] - ( CONSTANTS[5]*STATES[1]+ CONSTANTS[7]*STATES[3]+ CONSTANTS[9]*STATES[3]) - ( CONSTANTS[6]*STATES[2]+ CONSTANTS[8]*STATES[2]*STATES[4]);
resid[3] = RATES[3] -  CONSTANTS[8]*STATES[2]*STATES[4] - ( CONSTANTS[9]*STATES[3]+ CONSTANTS[7]*STATES[3]);
resid[4] = RATES[4] - ( CONSTANTS[9]*STATES[3]+ CONSTANTS[10]*STATES[5]) -  CONSTANTS[8]*STATES[2]*STATES[4];
resid[5] = RATES[5] - ( CONSTANTS[7]*STATES[3]+ CONSTANTS[12]*STATES[7]+ CONSTANTS[13]*STATES[7]) - ( CONSTANTS[10]*STATES[5]+ CONSTANTS[11]*STATES[5]*STATES[6]);
resid[6] = RATES[7] -  CONSTANTS[11]*STATES[5]*STATES[6] - ( CONSTANTS[12]*STATES[7]+ CONSTANTS[13]*STATES[7]);
resid[7] = RATES[6] - ( CONSTANTS[12]*STATES[7]+ CONSTANTS[14]*STATES[8]) -  CONSTANTS[11]*STATES[5]*STATES[6];
resid[8] = RATES[8] -  CONSTANTS[13]*STATES[7] -  CONSTANTS[14]*STATES[8];
}
void
computeVariables(double VOI, double* CONSTANTS, double* RATES, double* STATES, double* ALGEBRAIC)
{
ALGEBRAIC[0] =  (STATES[2]+STATES[3])*CONSTANTS[15];
ALGEBRAIC[1] =  (STATES[5]+STATES[7])*CONSTANTS[16];
ALGEBRAIC[2] =  STATES[8]*CONSTANTS[17];
}
void
computeEssentialVariables(double VOI, double* CONSTANTS, double* RATES, double* STATES, double* ALGEBRAIC)
{
}
void
getStateInformation(double* SI)
{
SI[0] = 1.0;
SI[1] = 1.0;
SI[2] = 1.0;
SI[3] = 1.0;
SI[4] = 1.0;
SI[5] = 1.0;
SI[6] = 1.0;
SI[7] = 1.0;
SI[8] = 1.0;
}
void
computeRoots(double VOI, double* CONSTANTS, double* RATES, double* OLDRATES, double* STATES,
             double* OLDSTATES, double* ALGEBRAIC, double* CONDVARS)
{
}