Generated Code

The following is python code generated by the CellML API from this CellML file. (Back to language selection)

The raw code is available.

# Size of variable arrays:
sizeAlgebraic = 89
sizeStates = 19
sizeConstants = 79
from math import *
from numpy import *

def createLegends():
    legend_states = [""] * sizeStates
    legend_rates = [""] * sizeStates
    legend_algebraic = [""] * sizeAlgebraic
    legend_voi = ""
    legend_constants = [""] * sizeConstants
    legend_voi = "time in component environment (ms)"
    legend_states[0] = "V in component cell (millivolt)"
    legend_constants[0] = "R in component cell (joule_per_kilomole_kelvin)"
    legend_constants[1] = "T in component cell (kelvin)"
    legend_constants[2] = "F in component cell (coulomb_per_mole)"
    legend_algebraic[3] = "I_st in component cell (microA_per_microF)"
    legend_algebraic[27] = "i_Na in component fast_sodium_current (microA_per_microF)"
    legend_algebraic[74] = "i_Ca_L in component L_type_Ca_channel (microA_per_microF)"
    legend_algebraic[79] = "i_Ca_T in component T_type_Ca_channel (microA_per_microF)"
    legend_algebraic[43] = "i_Kr in component rapid_delayed_rectifier_potassium_current (microA_per_microF)"
    legend_algebraic[76] = "i_Ks in component slow_delayed_rectifier_potassium_current (microA_per_microF)"
    legend_algebraic[54] = "i_K_Na in component sodium_activated_potassium_current (microA_per_microF)"
    legend_algebraic[84] = "i_NaCa in component Na_Ca_exchanger (microA_per_microF)"
    legend_algebraic[49] = "i_K1 in component time_independent_potassium_current (microA_per_microF)"
    legend_algebraic[44] = "i_K_ATP in component ATP_sensitive_potassium_current (microA_per_microF)"
    legend_algebraic[45] = "i_to in component transient_outward_current (microA_per_microF)"
    legend_algebraic[51] = "i_Kp in component plateau_potassium_current (microA_per_microF)"
    legend_algebraic[77] = "i_p_Ca in component sarcolemmal_calcium_pump (microA_per_microF)"
    legend_algebraic[55] = "i_Na_b in component sodium_background_current (microA_per_microF)"
    legend_algebraic[80] = "i_Ca_b in component calcium_background_current (microA_per_microF)"
    legend_algebraic[57] = "i_NaK in component sodium_potassium_pump (microA_per_microF)"
    legend_algebraic[83] = "i_ns_Ca in component non_specific_calcium_activated_current (microA_per_microF)"
    legend_algebraic[85] = "dVdt in component cell (microA_per_microF)"
    legend_constants[3] = "stim_start in component cell (ms)"
    legend_constants[4] = "stim_end in component cell (ms)"
    legend_constants[5] = "stim_period in component cell (ms)"
    legend_constants[6] = "stim_duration in component cell (ms)"
    legend_constants[7] = "stim_amplitude in component cell (microA_per_microF)"
    legend_algebraic[16] = "E_Na in component fast_sodium_current (millivolt)"
    legend_constants[8] = "g_Na in component fast_sodium_current (milliS_per_microF)"
    legend_states[1] = "Nai in component ionic_concentrations (millimolar)"
    legend_constants[9] = "Nao in component ionic_concentrations (millimolar)"
    legend_states[2] = "m in component fast_sodium_current_m_gate (dimensionless)"
    legend_states[3] = "h in component fast_sodium_current_h_gate (dimensionless)"
    legend_states[4] = "j in component fast_sodium_current_j_gate (dimensionless)"
    legend_algebraic[13] = "alpha_m in component fast_sodium_current_m_gate (per_ms)"
    legend_algebraic[26] = "beta_m in component fast_sodium_current_m_gate (per_ms)"
    legend_algebraic[0] = "E0_m in component fast_sodium_current_m_gate (millivolt)"
    legend_algebraic[1] = "alpha_h in component fast_sodium_current_h_gate (per_ms)"
    legend_algebraic[14] = "beta_h in component fast_sodium_current_h_gate (per_ms)"
    legend_algebraic[2] = "alpha_j in component fast_sodium_current_j_gate (per_ms)"
    legend_algebraic[15] = "beta_j in component fast_sodium_current_j_gate (per_ms)"
    legend_algebraic[69] = "i_CaCa in component L_type_Ca_channel (microA_per_microF)"
    legend_algebraic[72] = "i_CaK in component L_type_Ca_channel (microA_per_microF)"
    legend_algebraic[70] = "i_CaNa in component L_type_Ca_channel (microA_per_microF)"
    legend_constants[10] = "gamma_Nai in component L_type_Ca_channel (dimensionless)"
    legend_constants[11] = "gamma_Nao in component L_type_Ca_channel (dimensionless)"
    legend_constants[12] = "gamma_Ki in component L_type_Ca_channel (dimensionless)"
    legend_constants[13] = "gamma_Ko in component L_type_Ca_channel (dimensionless)"
    legend_constants[14] = "gamma_Cai in component L_type_Ca_channel (dimensionless)"
    legend_constants[15] = "gamma_Cao in component L_type_Ca_channel (dimensionless)"
    legend_algebraic[67] = "I_CaCa in component L_type_Ca_channel (microA_per_microF)"
    legend_algebraic[37] = "I_CaK in component L_type_Ca_channel (microA_per_microF)"
    legend_algebraic[32] = "I_CaNa in component L_type_Ca_channel (microA_per_microF)"
    legend_constants[16] = "P_Ca in component L_type_Ca_channel (litre_per_farad_millisecond)"
    legend_constants[17] = "P_Na in component L_type_Ca_channel (litre_per_farad_millisecond)"
    legend_constants[18] = "P_K in component L_type_Ca_channel (litre_per_farad_millisecond)"
    legend_algebraic[66] = "Cai in component calcium_dynamics (millimolar)"
    legend_constants[19] = "Cao in component calcium_dynamics (millimolar)"
    legend_constants[20] = "Ko in component ionic_concentrations (millimolar)"
    legend_states[5] = "Ki in component ionic_concentrations (millimolar)"
    legend_states[6] = "d in component L_type_Ca_channel_d_gate (dimensionless)"
    legend_states[7] = "f in component L_type_Ca_channel_f_gate (dimensionless)"
    legend_algebraic[68] = "f_Ca in component L_type_Ca_channel_f_Ca_gate (dimensionless)"
    legend_algebraic[33] = "alpha_d in component L_type_Ca_channel_d_gate (per_ms)"
    legend_algebraic[38] = "beta_d in component L_type_Ca_channel_d_gate (per_ms)"
    legend_algebraic[17] = "d_infinity in component L_type_Ca_channel_d_gate (dimensionless)"
    legend_algebraic[28] = "tau_d in component L_type_Ca_channel_d_gate (ms)"
    legend_algebraic[4] = "E0_d in component L_type_Ca_channel_d_gate (millivolt)"
    legend_algebraic[29] = "alpha_f in component L_type_Ca_channel_f_gate (per_ms)"
    legend_algebraic[34] = "beta_f in component L_type_Ca_channel_f_gate (per_ms)"
    legend_algebraic[5] = "f_infinity in component L_type_Ca_channel_f_gate (dimensionless)"
    legend_algebraic[18] = "tau_f in component L_type_Ca_channel_f_gate (ms)"
    legend_constants[21] = "Km_Ca in component L_type_Ca_channel_f_Ca_gate (millimolar)"
    legend_constants[22] = "g_CaT in component T_type_Ca_channel (milliS_per_microF)"
    legend_algebraic[78] = "E_Ca in component calcium_background_current (millivolt)"
    legend_states[8] = "b in component T_type_Ca_channel_b_gate (dimensionless)"
    legend_states[9] = "g in component T_type_Ca_channel_g_gate (dimensionless)"
    legend_algebraic[6] = "b_inf in component T_type_Ca_channel_b_gate (dimensionless)"
    legend_algebraic[19] = "tau_b in component T_type_Ca_channel_b_gate (ms)"
    legend_algebraic[7] = "g_inf in component T_type_Ca_channel_g_gate (dimensionless)"
    legend_algebraic[20] = "tau_g in component T_type_Ca_channel_g_gate (ms)"
    legend_constants[66] = "g_Kr in component rapid_delayed_rectifier_potassium_current (milliS_per_microF)"
    legend_constants[23] = "G_Kr in component rapid_delayed_rectifier_potassium_current (milliS_per_microF)"
    legend_algebraic[39] = "Rect in component rapid_delayed_rectifier_potassium_current (dimensionless)"
    legend_algebraic[42] = "E_K in component time_independent_potassium_current (millivolt)"
    legend_states[10] = "xr in component rapid_delayed_rectifier_potassium_current_xr_gate (dimensionless)"
    legend_algebraic[8] = "xr_infinity in component rapid_delayed_rectifier_potassium_current_xr_gate (dimensionless)"
    legend_algebraic[21] = "tau_xr in component rapid_delayed_rectifier_potassium_current_xr_gate (ms)"
    legend_algebraic[75] = "g_Ks in component slow_delayed_rectifier_potassium_current (milliS_per_microF)"
    legend_constants[24] = "G_Ks in component slow_delayed_rectifier_potassium_current (milliS_per_microF)"
    legend_algebraic[40] = "E_Ks in component slow_delayed_rectifier_potassium_current (millivolt)"
    legend_constants[25] = "PNaK in component slow_delayed_rectifier_potassium_current (dimensionless)"
    legend_states[11] = "xs1 in component slow_delayed_rectifier_potassium_current_xs1_gate (dimensionless)"
    legend_states[12] = "xs2 in component slow_delayed_rectifier_potassium_current_xs2_gate (dimensionless)"
    legend_algebraic[9] = "xs1_infinity in component slow_delayed_rectifier_potassium_current_xs1_gate (dimensionless)"
    legend_algebraic[22] = "tau_xs1 in component slow_delayed_rectifier_potassium_current_xs1_gate (ms)"
    legend_algebraic[10] = "xs2_infinity in component slow_delayed_rectifier_potassium_current_xs2_gate (dimensionless)"
    legend_algebraic[23] = "tau_xs2 in component slow_delayed_rectifier_potassium_current_xs2_gate (ms)"
    legend_constants[67] = "g_K_ATP in component ATP_sensitive_potassium_current (milliS_per_microF)"
    legend_constants[26] = "i_K_ATP_on in component ATP_sensitive_potassium_current (dimensionless)"
    legend_constants[27] = "nATP in component ATP_sensitive_potassium_current (dimensionless)"
    legend_constants[28] = "nicholsarea in component ATP_sensitive_potassium_current (dimensionless)"
    legend_constants[29] = "ATPi in component ATP_sensitive_potassium_current (millimolar)"
    legend_constants[30] = "hATP in component ATP_sensitive_potassium_current (dimensionless)"
    legend_constants[31] = "kATP in component ATP_sensitive_potassium_current (millimolar)"
    legend_constants[74] = "pATP in component ATP_sensitive_potassium_current (dimensionless)"
    legend_constants[76] = "GKbaraATP in component ATP_sensitive_potassium_current (milliS_per_microF)"
    legend_constants[68] = "g_to in component transient_outward_current (milliS_per_microF)"
    legend_algebraic[41] = "rvdv in component transient_outward_current (dimensionless)"
    legend_states[13] = "zdv in component transient_outward_current_zdv_gate (dimensionless)"
    legend_states[14] = "ydv in component transient_outward_current_ydv_gate (dimensionless)"
    legend_algebraic[11] = "alpha_zdv in component transient_outward_current_zdv_gate (per_ms)"
    legend_algebraic[24] = "beta_zdv in component transient_outward_current_zdv_gate (per_ms)"
    legend_algebraic[30] = "tau_zdv in component transient_outward_current_zdv_gate (ms)"
    legend_algebraic[35] = "zdv_ss in component transient_outward_current_zdv_gate (dimensionless)"
    legend_algebraic[12] = "alpha_ydv in component transient_outward_current_ydv_gate (per_ms)"
    legend_algebraic[25] = "beta_ydv in component transient_outward_current_ydv_gate (per_ms)"
    legend_algebraic[31] = "tau_ydv in component transient_outward_current_ydv_gate (ms)"
    legend_algebraic[36] = "ydv_ss in component transient_outward_current_ydv_gate (dimensionless)"
    legend_constants[69] = "g_K1 in component time_independent_potassium_current (milliS_per_microF)"
    legend_constants[32] = "G_K1 in component time_independent_potassium_current (milliS_per_microF)"
    legend_algebraic[48] = "K1_infinity in component time_independent_potassium_current_K1_gate (dimensionless)"
    legend_algebraic[46] = "alpha_K1 in component time_independent_potassium_current_K1_gate (per_ms)"
    legend_algebraic[47] = "beta_K1 in component time_independent_potassium_current_K1_gate (per_ms)"
    legend_constants[33] = "g_Kp in component plateau_potassium_current (milliS_per_microF)"
    legend_algebraic[50] = "Kp in component plateau_potassium_current (dimensionless)"
    legend_constants[34] = "g_K_Na in component sodium_activated_potassium_current (milliS_per_microF)"
    legend_constants[35] = "nKNa in component sodium_activated_potassium_current (dimensionless)"
    legend_algebraic[52] = "pona in component sodium_activated_potassium_current (dimensionless)"
    legend_algebraic[53] = "pov in component sodium_activated_potassium_current (dimensionless)"
    legend_constants[36] = "kdKNa in component sodium_activated_potassium_current (millimolar)"
    legend_constants[37] = "K_mpCa in component sarcolemmal_calcium_pump (millimolar)"
    legend_constants[38] = "I_pCa in component sarcolemmal_calcium_pump (microA_per_microF)"
    legend_constants[39] = "g_Nab in component sodium_background_current (milliS_per_microF)"
    legend_constants[40] = "g_Cab in component calcium_background_current (milliS_per_microF)"
    legend_constants[41] = "I_NaK in component sodium_potassium_pump (microA_per_microF)"
    legend_algebraic[56] = "f_NaK in component sodium_potassium_pump (dimensionless)"
    legend_constants[42] = "K_mNai in component sodium_potassium_pump (millimolar)"
    legend_constants[43] = "K_mKo in component sodium_potassium_pump (millimolar)"
    legend_constants[70] = "sigma in component sodium_potassium_pump (dimensionless)"
    legend_algebraic[81] = "i_ns_Na in component non_specific_calcium_activated_current (microA_per_microF)"
    legend_algebraic[82] = "i_ns_K in component non_specific_calcium_activated_current (microA_per_microF)"
    legend_constants[71] = "P_ns_Ca in component non_specific_calcium_activated_current (litre_per_farad_millisecond)"
    legend_algebraic[58] = "I_ns_Na in component non_specific_calcium_activated_current (microA_per_microF)"
    legend_algebraic[59] = "I_ns_K in component non_specific_calcium_activated_current (microA_per_microF)"
    legend_constants[44] = "K_m_ns_Ca in component non_specific_calcium_activated_current (millimolar)"
    legend_constants[45] = "c1 in component Na_Ca_exchanger (microA_per_microF)"
    legend_constants[46] = "c2 in component Na_Ca_exchanger (dimensionless)"
    legend_constants[47] = "gamma in component Na_Ca_exchanger (dimensionless)"
    legend_states[15] = "i_rel in component CICR_current (millimolar_per_ms)"
    legend_algebraic[86] = "i_up in component calcium_dynamics (millimolar_per_ms)"
    legend_algebraic[87] = "i_leak in component calcium_dynamics (millimolar_per_ms)"
    legend_algebraic[88] = "i_tr in component calcium_dynamics (millimolar_per_ms)"
    legend_constants[48] = "tau_tr in component calcium_dynamics (ms)"
    legend_constants[49] = "CSQN_max in component calcium_dynamics (millimolar)"
    legend_constants[50] = "K_mCSQN in component calcium_dynamics (millimolar)"
    legend_constants[51] = "K_mup in component calcium_dynamics (millimolar)"
    legend_constants[72] = "K_leak in component calcium_dynamics (per_ms)"
    legend_constants[52] = "I_up in component calcium_dynamics (millimolar_per_ms)"
    legend_constants[53] = "Ca_NSR_max in component calcium_dynamics (millimolar)"
    legend_states[16] = "CaT in component calcium_dynamics (millimolar)"
    legend_algebraic[62] = "Ca_JSR in component calcium_dynamics (millimolar)"
    legend_states[17] = "JSR in component calcium_dynamics (millimolar)"
    legend_states[18] = "NSR in component calcium_dynamics (millimolar)"
    legend_algebraic[60] = "bjsr in component calcium_dynamics (millimolar)"
    legend_algebraic[61] = "cjsr in component calcium_dynamics (millimolar2)"
    legend_algebraic[63] = "bmyo in component calcium_dynamics (millimolar)"
    legend_algebraic[64] = "cmyo in component calcium_dynamics (millimolar2)"
    legend_algebraic[65] = "dmyo in component calcium_dynamics (millimolar3)"
    legend_constants[75] = "V_myo in component geometry (micro_litre)"
    legend_constants[54] = "A_cap in component geometry (cm2)"
    legend_constants[77] = "V_JSR in component geometry (micro_litre)"
    legend_constants[78] = "V_NSR in component geometry (micro_litre)"
    legend_constants[55] = "K_mTRPN in component calcium_dynamics (millimolar)"
    legend_constants[56] = "K_mCMDN in component calcium_dynamics (millimolar)"
    legend_constants[57] = "TRPN_max in component calcium_dynamics (millimolar)"
    legend_constants[58] = "CMDN_max in component calcium_dynamics (millimolar)"
    legend_constants[59] = "kappa in component CICR_current (mM_per_millivolt_ms)"
    legend_constants[60] = "tau in component CICR_current (ms)"
    legend_constants[61] = "K_relss in component CICR_current (millimolar)"
    legend_constants[62] = "qn in component CICR_current (dimensionless)"
    legend_constants[65] = "alpha_rel in component CICR_current (millimolar_per_mV)"
    legend_algebraic[73] = "tau_rel in component CICR_current (ms)"
    legend_algebraic[71] = "I_relss in component CICR_current (millimolar_per_ms)"
    legend_constants[63] = "preplength in component geometry (mm)"
    legend_constants[64] = "radius in component geometry (mm)"
    legend_constants[73] = "volume in component geometry (micro_litre)"
    legend_rates[0] = "d/dt V in component cell (millivolt)"
    legend_rates[2] = "d/dt m in component fast_sodium_current_m_gate (dimensionless)"
    legend_rates[3] = "d/dt h in component fast_sodium_current_h_gate (dimensionless)"
    legend_rates[4] = "d/dt j in component fast_sodium_current_j_gate (dimensionless)"
    legend_rates[6] = "d/dt d in component L_type_Ca_channel_d_gate (dimensionless)"
    legend_rates[7] = "d/dt f in component L_type_Ca_channel_f_gate (dimensionless)"
    legend_rates[8] = "d/dt b in component T_type_Ca_channel_b_gate (dimensionless)"
    legend_rates[9] = "d/dt g in component T_type_Ca_channel_g_gate (dimensionless)"
    legend_rates[10] = "d/dt xr in component rapid_delayed_rectifier_potassium_current_xr_gate (dimensionless)"
    legend_rates[11] = "d/dt xs1 in component slow_delayed_rectifier_potassium_current_xs1_gate (dimensionless)"
    legend_rates[12] = "d/dt xs2 in component slow_delayed_rectifier_potassium_current_xs2_gate (dimensionless)"
    legend_rates[13] = "d/dt zdv in component transient_outward_current_zdv_gate (dimensionless)"
    legend_rates[14] = "d/dt ydv in component transient_outward_current_ydv_gate (dimensionless)"
    legend_rates[17] = "d/dt JSR in component calcium_dynamics (millimolar)"
    legend_rates[18] = "d/dt NSR in component calcium_dynamics (millimolar)"
    legend_rates[16] = "d/dt CaT in component calcium_dynamics (millimolar)"
    legend_rates[15] = "d/dt i_rel in component CICR_current (millimolar_per_ms)"
    legend_rates[1] = "d/dt Nai in component ionic_concentrations (millimolar)"
    legend_rates[5] = "d/dt Ki in component ionic_concentrations (millimolar)"
    return (legend_states, legend_algebraic, legend_voi, legend_constants)

def initConsts():
    constants = [0.0] * sizeConstants; states = [0.0] * sizeStates;
    states[0] = -84.1873796338053
    constants[0] = 8314
    constants[1] = 310
    constants[2] = 96485
    constants[3] = 10
    constants[4] = 9e6
    constants[5] = 300
    constants[6] = 0.5
    constants[7] = -80
    constants[8] = 16
    states[1] = 17.6117490445233
    constants[9] = 140
    states[2] = 0.00176916305136317
    states[3] = 0.981794631652901
    states[4] = 0.988104917040651
    constants[10] = 0.75
    constants[11] = 0.75
    constants[12] = 0.75
    constants[13] = 0.75
    constants[14] = 1
    constants[15] = 0.341
    constants[16] = 0.00054
    constants[17] = 6.75e-7
    constants[18] = 1.93e-7
    constants[19] = 1.8
    constants[20] = 5.4
    states[5] = 136.516534944494
    states[6] = 6.86847510834054e-06
    states[7] = 0.983904806551856
    constants[21] = 0.0006
    constants[22] = 0.056
    states[8] = 0.00107239754072387
    states[9] = 0.592188823541168
    constants[23] = 0.02614
    states[10] = 0.0068050628191769
    constants[24] = 0.433
    constants[25] = 0.01833
    states[11] = 0.053484483308799
    states[12] = 0.0915338818524544
    constants[26] = 1
    constants[27] = 0.24
    constants[28] = 5e-5
    constants[29] = 3
    constants[30] = 2
    constants[31] = 0.00025
    states[13] = 0.0153950987302045
    states[14] = 0.931914460539262
    constants[32] = 0.75
    constants[33] = 0.00552
    constants[34] = 0.12848
    constants[35] = 2.8
    constants[36] = 66
    constants[37] = 0.0005
    constants[38] = 1.15
    constants[39] = 0.004
    constants[40] = 0.003016
    constants[41] = 2.25
    constants[42] = 10
    constants[43] = 1.5
    constants[44] = 0.0012
    constants[45] = 0.00025
    constants[46] = 0.0001
    constants[47] = 0.15
    states[15] = 0.000948968144034608
    constants[48] = 120
    constants[49] = 10
    constants[50] = 0.8
    constants[51] = 0.00092
    constants[52] = 0.00875
    constants[53] = 15
    states[16] = 0.0354676562409019
    states[17] = 7.64464040842916
    states[18] = 3.35408001677624
    constants[54] = 1.534e-4
    constants[55] = 0.0005
    constants[56] = 0.00238
    constants[57] = 0.07
    constants[58] = 0.05
    constants[59] = 0.125
    constants[60] = 4.75
    constants[61] = 1
    constants[62] = 9
    constants[63] = 0.1
    constants[64] = 0.011
    constants[65] = constants[59]*constants[60]
    constants[66] = constants[23]*(power(constants[20]/5.40000, 1.0/2))
    constants[67] = (constants[26]*0.000193000)/constants[28]
    constants[68] = 0.00000*0.500000
    constants[69] = constants[32]*(power(constants[20]/5.40000, 1.0/2))
    constants[70] = (1.00000/7.00000)*(exp(constants[9]/67.3000)-1.00000)
    constants[71] = 1.75000e-07
    constants[72] = constants[52]/constants[53]
    constants[73] =  pi*constants[63]*(power(constants[64], 2.00000))
    constants[74] = 1.00000/(1.00000+power(constants[29]/constants[31], constants[30]))
    constants[75] = 0.680000*constants[73]
    constants[76] = constants[67]*constants[74]*(power(constants[20]/4.00000, constants[27]))
    constants[77] = 0.00480000*constants[73]
    constants[78] = 0.0552000*constants[73]
    return (states, constants)

def computeRates(voi, states, constants):
    rates = [0.0] * sizeStates; algebraic = [0.0] * sizeAlgebraic
    algebraic[1] = custom_piecewise([less(states[0] , -40.0000), 0.135000*exp((80.0000+states[0])/-6.80000) , True, 0.00000])
    algebraic[14] = custom_piecewise([less(states[0] , -40.0000), 3.56000*exp(0.0790000*states[0])+310000.*exp(0.350000*states[0]) , True, 1.00000/(0.130000*(1.00000+exp((states[0]+10.6600)/-11.1000)))])
    rates[3] = algebraic[1]*(1.00000-states[3])-algebraic[14]*states[3]
    algebraic[2] = custom_piecewise([less(states[0] , -40.0000), (-(127140.*exp(0.244400*states[0])+3.47400e-05*exp(-0.0439100*states[0]))*(states[0]+37.7800))/(1.00000+exp(0.311000*(states[0]+79.2300))) , True, 0.00000])
    algebraic[15] = custom_piecewise([less(states[0] , -40.0000), (0.121200*exp(-0.0105200*states[0]))/(1.00000+exp(-0.137800*(states[0]+40.1400))) , True, (0.300000*exp(-2.53500e-07*states[0]))/(1.00000+exp(-0.100000*(states[0]+32.0000)))])
    rates[4] = algebraic[2]*(1.00000-states[4])-algebraic[15]*states[4]
    algebraic[6] = 1.00000/(1.00000+exp(-(states[0]+50.0000)/5.00000))
    algebraic[19] = 5.00000/(1.06800*exp((states[0]+16.3000)/30.0000)+1.06800*exp(-(states[0]+16.3000)/30.0000))
    rates[8] = (algebraic[6]-states[8])/algebraic[19]
    algebraic[7] = 1.00000/(1.00000+exp((states[0]+61.0000)/5.00000))
    algebraic[20] = 5.00000/(0.0150000*exp(-(states[0]+71.7000)/83.3000)+0.0150000*exp((states[0]+71.7000)/15.4000))
    rates[9] = (algebraic[7]-states[9])/algebraic[20]
    algebraic[8] = 1.00000/(1.00000+exp(-(states[0]+21.5000)/7.50000))
    algebraic[21] = 1.00000/((0.00138000*(states[0]+14.2000))/(1.00000-exp(-0.123000*(states[0]+14.2000)))+(0.000610000*(states[0]+38.9000))/(exp(0.145000*(states[0]+38.9000))-1.00000))
    rates[10] = (algebraic[8]-states[10])/algebraic[21]
    algebraic[9] = 1.00000/(1.00000+exp(-(states[0]-1.50000)/16.7000))
    algebraic[22] = 1.00000/((7.19000e-05*(states[0]+30.0000))/(1.00000-exp(-0.148000*(states[0]+30.0000)))+(0.000131000*(states[0]+30.0000))/(exp(0.0687000*(states[0]+30.0000))-1.00000))
    rates[11] = (algebraic[9]-states[11])/algebraic[22]
    algebraic[10] = 1.00000/(1.00000+exp(-(states[0]-1.50000)/16.7000))
    algebraic[23] = 4.00000/((7.19000e-05*(states[0]+30.0000))/(1.00000-exp(-0.148000*(states[0]+30.0000)))+(0.000131000*(states[0]+30.0000))/(exp(0.0687000*(states[0]+30.0000))-1.00000))
    rates[12] = (algebraic[10]-states[12])/algebraic[23]
    algebraic[0] = states[0]+47.1300
    algebraic[13] = (0.320000*algebraic[0])/(1.00000-exp(-0.100000*algebraic[0]))
    algebraic[26] = 0.0800000*exp(-states[0]/11.0000)
    rates[2] = algebraic[13]*(1.00000-states[2])-algebraic[26]*states[2]
    algebraic[5] = 1.00000/(1.00000+exp((states[0]+32.0000)/8.00000))+0.600000/(1.00000+exp((50.0000-states[0])/20.0000))
    algebraic[18] = 1.00000/(0.0197000*exp(-(power(0.0337000*(states[0]+10.0000), 2.00000)))+0.0200000)
    algebraic[29] = algebraic[5]/algebraic[18]
    algebraic[34] = (1.00000-algebraic[5])/algebraic[18]
    rates[7] = algebraic[29]*(1.00000-states[7])-algebraic[34]*states[7]
    algebraic[11] = (10.0000*exp((states[0]-40.0000)/25.0000))/(1.00000+exp((states[0]-40.0000)/25.0000))
    algebraic[24] = (10.0000*exp(-(states[0]+90.0000)/25.0000))/(1.00000+exp(-(states[0]+90.0000)/25.0000))
    algebraic[30] = 1.00000/(algebraic[11]+algebraic[24])
    algebraic[35] = algebraic[11]/(algebraic[11]+algebraic[24])
    rates[13] = (algebraic[35]-states[13])/algebraic[30]
    algebraic[12] = 0.0150000/(1.00000+exp((states[0]+60.0000)/5.00000))
    algebraic[25] = (0.100000*exp((states[0]+25.0000)/5.00000))/(1.00000+exp((states[0]+25.0000)/5.00000))
    algebraic[31] = 1.00000/(algebraic[12]+algebraic[25])
    algebraic[36] = algebraic[12]/(algebraic[12]+algebraic[25])
    rates[14] = (algebraic[36]-states[14])/algebraic[31]
    algebraic[4] = states[0]+10.0000
    algebraic[17] = 1.00000/(1.00000+exp(-algebraic[4]/6.24000))
    algebraic[28] = (1.00000*algebraic[17]*(1.00000-exp(-algebraic[4]/6.24000)))/(0.0350000*algebraic[4])
    algebraic[33] = algebraic[17]/algebraic[28]
    algebraic[38] = (1.00000-algebraic[17])/algebraic[28]
    rates[6] = algebraic[33]*(1.00000-states[6])-algebraic[38]*states[6]
    algebraic[60] = constants[49]+constants[50]+-states[17]
    algebraic[61] = constants[50]*states[17]
    algebraic[62] = (power(power(algebraic[60], 2.00000)+4.00000*algebraic[61], 1.0/2)-algebraic[60])/2.00000
    algebraic[73] = constants[60]/(1.00000+0.0123000/algebraic[62])
    algebraic[63] = constants[58]+constants[57]+constants[56]+constants[55]+-states[16]
    algebraic[64] = constants[56]*constants[55]+constants[57]*constants[56]+constants[58]*constants[55]+-states[16]*(constants[55]+constants[56])
    algebraic[65] = -constants[55]*constants[56]*states[16]
    algebraic[66] = (2.00000/3.00000)*(power(power(algebraic[63], 2.00000)-3.00000*algebraic[64], 1.0/2))*cos(arccos((9.00000*algebraic[63]*algebraic[64]-(2.00000*(power(algebraic[63], 3.00000))+27.0000*algebraic[65]))/(2.00000*(power(power(power(algebraic[63], 2.00000)-3.00000*algebraic[64], 3.00000), 1.0/2))))/3.00000)-algebraic[63]/3.00000
    algebraic[67] = (((constants[16]*(power(2.00000, 2.00000))*states[0]*(power(constants[2], 2.00000)))/(constants[0]*constants[1]))*(constants[14]*algebraic[66]*exp((2.00000*states[0]*constants[2])/(constants[0]*constants[1]))-constants[15]*constants[19]))/(exp((2.00000*states[0]*constants[2])/(constants[0]*constants[1]))-1.00000)
    algebraic[68] = 1.00000/(1.00000+algebraic[66]/constants[21])
    algebraic[69] = states[6]*states[7]*algebraic[68]*algebraic[67]
    algebraic[71] = (algebraic[69]*constants[65])/(1.00000+power(constants[61]/algebraic[62], constants[62]))
    rates[15] = -(algebraic[71]+states[15])/algebraic[73]
    algebraic[3] = custom_piecewise([greater_equal(voi , constants[3]) & less_equal(voi , constants[4]) & less_equal((voi-constants[3])-floor((voi-constants[3])/constants[5])*constants[5] , constants[6]), constants[7] , True, 0.00000])
    algebraic[39] = 1.00000/(1.00000+exp((states[0]+9.00000)/22.4000))
    algebraic[42] = ((constants[0]*constants[1])/constants[2])*log(constants[20]/states[5])
    algebraic[43] = constants[66]*states[10]*algebraic[39]*(states[0]-algebraic[42])
    algebraic[75] = constants[24]*(1.00000+0.600000/(1.00000+power(3.80000e-05/algebraic[66], 1.40000)))
    algebraic[40] = ((constants[0]*constants[1])/constants[2])*log((constants[20]+constants[25]*constants[9])/(states[5]+constants[25]*states[1]))
    algebraic[76] = algebraic[75]*states[11]*states[12]*(states[0]-algebraic[40])
    algebraic[52] = 0.850000/(1.00000+power(constants[36]/states[1], constants[35]))
    algebraic[53] = 0.800000-0.650000/(1.00000+exp((states[0]+125.000)/15.0000))
    algebraic[54] = constants[34]*algebraic[52]*algebraic[53]*(states[0]-algebraic[42])
    algebraic[46] = 1.02000/(1.00000+exp(0.238500*((states[0]-algebraic[42])-59.2150)))
    algebraic[47] = (1.00000*(0.491240*exp(0.0803200*((states[0]-algebraic[42])+5.47600))+exp(0.0617500*((states[0]-algebraic[42])-594.310))))/(1.00000+exp(-0.514300*((states[0]-algebraic[42])+4.75300)))
    algebraic[48] = algebraic[46]/(algebraic[46]+algebraic[47])
    algebraic[49] = constants[69]*algebraic[48]*(states[0]-algebraic[42])
    algebraic[44] = constants[76]*(states[0]-algebraic[42])
    algebraic[41] = exp(states[0]/100.000)
    algebraic[45] = constants[68]*(power(states[13], 3.00000))*states[14]*algebraic[41]*(states[0]-algebraic[42])
    algebraic[50] = 1.00000/(1.00000+exp((7.48800-states[0])/5.98000))
    algebraic[51] = constants[33]*algebraic[50]*(states[0]-algebraic[42])
    algebraic[56] = 1.00000/(1.00000+0.124500*exp((-0.100000*states[0]*constants[2])/(constants[0]*constants[1]))+0.0365000*constants[70]*exp((-states[0]*constants[2])/(constants[0]*constants[1])))
    algebraic[57] = ((constants[41]*algebraic[56])/(1.00000+power(constants[42]/states[1], 2.00000)))/(1.00000+constants[43]/constants[20])
    algebraic[37] = (((constants[18]*(power(1.00000, 2.00000))*states[0]*(power(constants[2], 2.00000)))/(constants[0]*constants[1]))*(constants[12]*states[5]*exp((1.00000*states[0]*constants[2])/(constants[0]*constants[1]))-constants[13]*constants[20]))/(exp((1.00000*states[0]*constants[2])/(constants[0]*constants[1]))-1.00000)
    algebraic[72] = states[6]*states[7]*algebraic[68]*algebraic[37]
    algebraic[59] = (((constants[71]*(power(1.00000, 2.00000))*states[0]*(power(constants[2], 2.00000)))/(constants[0]*constants[1]))*(constants[12]*states[5]*exp((1.00000*states[0]*constants[2])/(constants[0]*constants[1]))-constants[13]*constants[20]))/(exp((1.00000*states[0]*constants[2])/(constants[0]*constants[1]))-1.00000)
    algebraic[82] = (algebraic[59]*1.00000)/(1.00000+power(constants[44]/algebraic[66], 3.00000))
    rates[5] = (-1.00000*(algebraic[3]+algebraic[72]+algebraic[43]+algebraic[76]+algebraic[49]+algebraic[44]+algebraic[45]+algebraic[51]+algebraic[54]+algebraic[82]+-algebraic[57]*2.00000)*constants[54])/(constants[75]*constants[2])
    algebraic[16] = ((constants[0]*constants[1])/constants[2])*log(constants[9]/states[1])
    algebraic[27] = constants[8]*(power(states[2], 3.00000))*states[3]*states[4]*(states[0]-algebraic[16])
    algebraic[84] = (constants[45]*exp(((constants[47]-1.00000)*states[0]*constants[2])/(constants[0]*constants[1]))*(exp((states[0]*constants[2])/(constants[0]*constants[1]))*(power(states[1], 3.00000))*constants[19]-(power(constants[9], 3.00000))*algebraic[66]))/(1.00000+constants[46]*exp(((constants[47]-1.00000)*states[0]*constants[2])/(constants[0]*constants[1]))*(exp((states[0]*constants[2])/(constants[0]*constants[1]))*(power(states[1], 3.00000))*constants[19]+(power(constants[9], 3.00000))*algebraic[66]))
    algebraic[55] = constants[39]*(states[0]-algebraic[16])
    algebraic[32] = (((constants[17]*(power(1.00000, 2.00000))*states[0]*(power(constants[2], 2.00000)))/(constants[0]*constants[1]))*(constants[10]*states[1]*exp((1.00000*states[0]*constants[2])/(constants[0]*constants[1]))-constants[11]*constants[9]))/(exp((1.00000*states[0]*constants[2])/(constants[0]*constants[1]))-1.00000)
    algebraic[70] = states[6]*states[7]*algebraic[68]*algebraic[32]
    algebraic[58] = (((constants[71]*(power(1.00000, 2.00000))*states[0]*(power(constants[2], 2.00000)))/(constants[0]*constants[1]))*(constants[10]*states[1]*exp((1.00000*states[0]*constants[2])/(constants[0]*constants[1]))-constants[11]*constants[9]))/(exp((1.00000*states[0]*constants[2])/(constants[0]*constants[1]))-1.00000)
    algebraic[81] = (algebraic[58]*1.00000)/(1.00000+power(constants[44]/algebraic[66], 3.00000))
    rates[1] = (-1.00000*(algebraic[27]+algebraic[70]+algebraic[55]+algebraic[81]+algebraic[84]*3.00000+algebraic[57]*3.00000)*constants[54])/(constants[75]*constants[2])
    algebraic[74] = algebraic[69]+algebraic[72]+algebraic[70]
    algebraic[78] = ((constants[0]*constants[1])/(2.00000*constants[2]))*log(constants[19]/algebraic[66])
    algebraic[79] = constants[22]*states[8]*states[8]*states[9]*(states[0]-algebraic[78])
    algebraic[77] = (constants[38]*algebraic[66])/(constants[37]+algebraic[66])
    algebraic[80] = constants[40]*(states[0]-algebraic[78])
    algebraic[83] = algebraic[81]+algebraic[82]
    algebraic[85] = -(algebraic[27]+algebraic[74]+algebraic[79]+algebraic[43]+algebraic[76]+algebraic[54]+algebraic[49]+algebraic[44]+algebraic[45]+algebraic[51]+algebraic[84]+algebraic[77]+algebraic[55]+algebraic[80]+algebraic[57]+algebraic[83]+algebraic[3])
    rates[0] = algebraic[85]
    algebraic[86] = (constants[52]*algebraic[66])/(algebraic[66]+constants[51])
    algebraic[87] = constants[72]*states[18]
    rates[16] = (-1.00000*constants[54]*(algebraic[69]+algebraic[79]+algebraic[77]+algebraic[80]+-2.00000*algebraic[84]))/(2.00000*constants[75]*constants[2])+(states[15]*constants[77])/constants[75]+((algebraic[87]-algebraic[86])*constants[78])/constants[75]
    algebraic[88] = (states[18]-algebraic[62])/constants[48]
    rates[17] = algebraic[88]-states[15]
    rates[18] = ((-algebraic[88]*constants[77])/constants[78]-algebraic[87])+algebraic[86]
    return(rates)

def computeAlgebraic(constants, states, voi):
    algebraic = array([[0.0] * len(voi)] * sizeAlgebraic)
    states = array(states)
    voi = array(voi)
    algebraic[1] = custom_piecewise([less(states[0] , -40.0000), 0.135000*exp((80.0000+states[0])/-6.80000) , True, 0.00000])
    algebraic[14] = custom_piecewise([less(states[0] , -40.0000), 3.56000*exp(0.0790000*states[0])+310000.*exp(0.350000*states[0]) , True, 1.00000/(0.130000*(1.00000+exp((states[0]+10.6600)/-11.1000)))])
    algebraic[2] = custom_piecewise([less(states[0] , -40.0000), (-(127140.*exp(0.244400*states[0])+3.47400e-05*exp(-0.0439100*states[0]))*(states[0]+37.7800))/(1.00000+exp(0.311000*(states[0]+79.2300))) , True, 0.00000])
    algebraic[15] = custom_piecewise([less(states[0] , -40.0000), (0.121200*exp(-0.0105200*states[0]))/(1.00000+exp(-0.137800*(states[0]+40.1400))) , True, (0.300000*exp(-2.53500e-07*states[0]))/(1.00000+exp(-0.100000*(states[0]+32.0000)))])
    algebraic[6] = 1.00000/(1.00000+exp(-(states[0]+50.0000)/5.00000))
    algebraic[19] = 5.00000/(1.06800*exp((states[0]+16.3000)/30.0000)+1.06800*exp(-(states[0]+16.3000)/30.0000))
    algebraic[7] = 1.00000/(1.00000+exp((states[0]+61.0000)/5.00000))
    algebraic[20] = 5.00000/(0.0150000*exp(-(states[0]+71.7000)/83.3000)+0.0150000*exp((states[0]+71.7000)/15.4000))
    algebraic[8] = 1.00000/(1.00000+exp(-(states[0]+21.5000)/7.50000))
    algebraic[21] = 1.00000/((0.00138000*(states[0]+14.2000))/(1.00000-exp(-0.123000*(states[0]+14.2000)))+(0.000610000*(states[0]+38.9000))/(exp(0.145000*(states[0]+38.9000))-1.00000))
    algebraic[9] = 1.00000/(1.00000+exp(-(states[0]-1.50000)/16.7000))
    algebraic[22] = 1.00000/((7.19000e-05*(states[0]+30.0000))/(1.00000-exp(-0.148000*(states[0]+30.0000)))+(0.000131000*(states[0]+30.0000))/(exp(0.0687000*(states[0]+30.0000))-1.00000))
    algebraic[10] = 1.00000/(1.00000+exp(-(states[0]-1.50000)/16.7000))
    algebraic[23] = 4.00000/((7.19000e-05*(states[0]+30.0000))/(1.00000-exp(-0.148000*(states[0]+30.0000)))+(0.000131000*(states[0]+30.0000))/(exp(0.0687000*(states[0]+30.0000))-1.00000))
    algebraic[0] = states[0]+47.1300
    algebraic[13] = (0.320000*algebraic[0])/(1.00000-exp(-0.100000*algebraic[0]))
    algebraic[26] = 0.0800000*exp(-states[0]/11.0000)
    algebraic[5] = 1.00000/(1.00000+exp((states[0]+32.0000)/8.00000))+0.600000/(1.00000+exp((50.0000-states[0])/20.0000))
    algebraic[18] = 1.00000/(0.0197000*exp(-(power(0.0337000*(states[0]+10.0000), 2.00000)))+0.0200000)
    algebraic[29] = algebraic[5]/algebraic[18]
    algebraic[34] = (1.00000-algebraic[5])/algebraic[18]
    algebraic[11] = (10.0000*exp((states[0]-40.0000)/25.0000))/(1.00000+exp((states[0]-40.0000)/25.0000))
    algebraic[24] = (10.0000*exp(-(states[0]+90.0000)/25.0000))/(1.00000+exp(-(states[0]+90.0000)/25.0000))
    algebraic[30] = 1.00000/(algebraic[11]+algebraic[24])
    algebraic[35] = algebraic[11]/(algebraic[11]+algebraic[24])
    algebraic[12] = 0.0150000/(1.00000+exp((states[0]+60.0000)/5.00000))
    algebraic[25] = (0.100000*exp((states[0]+25.0000)/5.00000))/(1.00000+exp((states[0]+25.0000)/5.00000))
    algebraic[31] = 1.00000/(algebraic[12]+algebraic[25])
    algebraic[36] = algebraic[12]/(algebraic[12]+algebraic[25])
    algebraic[4] = states[0]+10.0000
    algebraic[17] = 1.00000/(1.00000+exp(-algebraic[4]/6.24000))
    algebraic[28] = (1.00000*algebraic[17]*(1.00000-exp(-algebraic[4]/6.24000)))/(0.0350000*algebraic[4])
    algebraic[33] = algebraic[17]/algebraic[28]
    algebraic[38] = (1.00000-algebraic[17])/algebraic[28]
    algebraic[60] = constants[49]+constants[50]+-states[17]
    algebraic[61] = constants[50]*states[17]
    algebraic[62] = (power(power(algebraic[60], 2.00000)+4.00000*algebraic[61], 1.0/2)-algebraic[60])/2.00000
    algebraic[73] = constants[60]/(1.00000+0.0123000/algebraic[62])
    algebraic[63] = constants[58]+constants[57]+constants[56]+constants[55]+-states[16]
    algebraic[64] = constants[56]*constants[55]+constants[57]*constants[56]+constants[58]*constants[55]+-states[16]*(constants[55]+constants[56])
    algebraic[65] = -constants[55]*constants[56]*states[16]
    algebraic[66] = (2.00000/3.00000)*(power(power(algebraic[63], 2.00000)-3.00000*algebraic[64], 1.0/2))*cos(arccos((9.00000*algebraic[63]*algebraic[64]-(2.00000*(power(algebraic[63], 3.00000))+27.0000*algebraic[65]))/(2.00000*(power(power(power(algebraic[63], 2.00000)-3.00000*algebraic[64], 3.00000), 1.0/2))))/3.00000)-algebraic[63]/3.00000
    algebraic[67] = (((constants[16]*(power(2.00000, 2.00000))*states[0]*(power(constants[2], 2.00000)))/(constants[0]*constants[1]))*(constants[14]*algebraic[66]*exp((2.00000*states[0]*constants[2])/(constants[0]*constants[1]))-constants[15]*constants[19]))/(exp((2.00000*states[0]*constants[2])/(constants[0]*constants[1]))-1.00000)
    algebraic[68] = 1.00000/(1.00000+algebraic[66]/constants[21])
    algebraic[69] = states[6]*states[7]*algebraic[68]*algebraic[67]
    algebraic[71] = (algebraic[69]*constants[65])/(1.00000+power(constants[61]/algebraic[62], constants[62]))
    algebraic[3] = custom_piecewise([greater_equal(voi , constants[3]) & less_equal(voi , constants[4]) & less_equal((voi-constants[3])-floor((voi-constants[3])/constants[5])*constants[5] , constants[6]), constants[7] , True, 0.00000])
    algebraic[39] = 1.00000/(1.00000+exp((states[0]+9.00000)/22.4000))
    algebraic[42] = ((constants[0]*constants[1])/constants[2])*log(constants[20]/states[5])
    algebraic[43] = constants[66]*states[10]*algebraic[39]*(states[0]-algebraic[42])
    algebraic[75] = constants[24]*(1.00000+0.600000/(1.00000+power(3.80000e-05/algebraic[66], 1.40000)))
    algebraic[40] = ((constants[0]*constants[1])/constants[2])*log((constants[20]+constants[25]*constants[9])/(states[5]+constants[25]*states[1]))
    algebraic[76] = algebraic[75]*states[11]*states[12]*(states[0]-algebraic[40])
    algebraic[52] = 0.850000/(1.00000+power(constants[36]/states[1], constants[35]))
    algebraic[53] = 0.800000-0.650000/(1.00000+exp((states[0]+125.000)/15.0000))
    algebraic[54] = constants[34]*algebraic[52]*algebraic[53]*(states[0]-algebraic[42])
    algebraic[46] = 1.02000/(1.00000+exp(0.238500*((states[0]-algebraic[42])-59.2150)))
    algebraic[47] = (1.00000*(0.491240*exp(0.0803200*((states[0]-algebraic[42])+5.47600))+exp(0.0617500*((states[0]-algebraic[42])-594.310))))/(1.00000+exp(-0.514300*((states[0]-algebraic[42])+4.75300)))
    algebraic[48] = algebraic[46]/(algebraic[46]+algebraic[47])
    algebraic[49] = constants[69]*algebraic[48]*(states[0]-algebraic[42])
    algebraic[44] = constants[76]*(states[0]-algebraic[42])
    algebraic[41] = exp(states[0]/100.000)
    algebraic[45] = constants[68]*(power(states[13], 3.00000))*states[14]*algebraic[41]*(states[0]-algebraic[42])
    algebraic[50] = 1.00000/(1.00000+exp((7.48800-states[0])/5.98000))
    algebraic[51] = constants[33]*algebraic[50]*(states[0]-algebraic[42])
    algebraic[56] = 1.00000/(1.00000+0.124500*exp((-0.100000*states[0]*constants[2])/(constants[0]*constants[1]))+0.0365000*constants[70]*exp((-states[0]*constants[2])/(constants[0]*constants[1])))
    algebraic[57] = ((constants[41]*algebraic[56])/(1.00000+power(constants[42]/states[1], 2.00000)))/(1.00000+constants[43]/constants[20])
    algebraic[37] = (((constants[18]*(power(1.00000, 2.00000))*states[0]*(power(constants[2], 2.00000)))/(constants[0]*constants[1]))*(constants[12]*states[5]*exp((1.00000*states[0]*constants[2])/(constants[0]*constants[1]))-constants[13]*constants[20]))/(exp((1.00000*states[0]*constants[2])/(constants[0]*constants[1]))-1.00000)
    algebraic[72] = states[6]*states[7]*algebraic[68]*algebraic[37]
    algebraic[59] = (((constants[71]*(power(1.00000, 2.00000))*states[0]*(power(constants[2], 2.00000)))/(constants[0]*constants[1]))*(constants[12]*states[5]*exp((1.00000*states[0]*constants[2])/(constants[0]*constants[1]))-constants[13]*constants[20]))/(exp((1.00000*states[0]*constants[2])/(constants[0]*constants[1]))-1.00000)
    algebraic[82] = (algebraic[59]*1.00000)/(1.00000+power(constants[44]/algebraic[66], 3.00000))
    algebraic[16] = ((constants[0]*constants[1])/constants[2])*log(constants[9]/states[1])
    algebraic[27] = constants[8]*(power(states[2], 3.00000))*states[3]*states[4]*(states[0]-algebraic[16])
    algebraic[84] = (constants[45]*exp(((constants[47]-1.00000)*states[0]*constants[2])/(constants[0]*constants[1]))*(exp((states[0]*constants[2])/(constants[0]*constants[1]))*(power(states[1], 3.00000))*constants[19]-(power(constants[9], 3.00000))*algebraic[66]))/(1.00000+constants[46]*exp(((constants[47]-1.00000)*states[0]*constants[2])/(constants[0]*constants[1]))*(exp((states[0]*constants[2])/(constants[0]*constants[1]))*(power(states[1], 3.00000))*constants[19]+(power(constants[9], 3.00000))*algebraic[66]))
    algebraic[55] = constants[39]*(states[0]-algebraic[16])
    algebraic[32] = (((constants[17]*(power(1.00000, 2.00000))*states[0]*(power(constants[2], 2.00000)))/(constants[0]*constants[1]))*(constants[10]*states[1]*exp((1.00000*states[0]*constants[2])/(constants[0]*constants[1]))-constants[11]*constants[9]))/(exp((1.00000*states[0]*constants[2])/(constants[0]*constants[1]))-1.00000)
    algebraic[70] = states[6]*states[7]*algebraic[68]*algebraic[32]
    algebraic[58] = (((constants[71]*(power(1.00000, 2.00000))*states[0]*(power(constants[2], 2.00000)))/(constants[0]*constants[1]))*(constants[10]*states[1]*exp((1.00000*states[0]*constants[2])/(constants[0]*constants[1]))-constants[11]*constants[9]))/(exp((1.00000*states[0]*constants[2])/(constants[0]*constants[1]))-1.00000)
    algebraic[81] = (algebraic[58]*1.00000)/(1.00000+power(constants[44]/algebraic[66], 3.00000))
    algebraic[74] = algebraic[69]+algebraic[72]+algebraic[70]
    algebraic[78] = ((constants[0]*constants[1])/(2.00000*constants[2]))*log(constants[19]/algebraic[66])
    algebraic[79] = constants[22]*states[8]*states[8]*states[9]*(states[0]-algebraic[78])
    algebraic[77] = (constants[38]*algebraic[66])/(constants[37]+algebraic[66])
    algebraic[80] = constants[40]*(states[0]-algebraic[78])
    algebraic[83] = algebraic[81]+algebraic[82]
    algebraic[85] = -(algebraic[27]+algebraic[74]+algebraic[79]+algebraic[43]+algebraic[76]+algebraic[54]+algebraic[49]+algebraic[44]+algebraic[45]+algebraic[51]+algebraic[84]+algebraic[77]+algebraic[55]+algebraic[80]+algebraic[57]+algebraic[83]+algebraic[3])
    algebraic[86] = (constants[52]*algebraic[66])/(algebraic[66]+constants[51])
    algebraic[87] = constants[72]*states[18]
    algebraic[88] = (states[18]-algebraic[62])/constants[48]
    return algebraic

def custom_piecewise(cases):
    """Compute result of a piecewise function"""
    return select(cases[0::2],cases[1::2])

def solve_model():
    """Solve model with ODE solver"""
    from scipy.integrate import ode
    # Initialise constants and state variables
    (init_states, constants) = initConsts()

    # Set timespan to solve over
    voi = linspace(0, 10, 500)

    # Construct ODE object to solve
    r = ode(computeRates)
    r.set_integrator('vode', method='bdf', atol=1e-06, rtol=1e-06, max_step=1)
    r.set_initial_value(init_states, voi[0])
    r.set_f_params(constants)

    # Solve model
    states = array([[0.0] * len(voi)] * sizeStates)
    states[:,0] = init_states
    for (i,t) in enumerate(voi[1:]):
        if r.successful():
            r.integrate(t)
            states[:,i+1] = r.y
        else:
            break

    # Compute algebraic variables
    algebraic = computeAlgebraic(constants, states, voi)
    return (voi, states, algebraic)

def plot_model(voi, states, algebraic):
    """Plot variables against variable of integration"""
    import pylab
    (legend_states, legend_algebraic, legend_voi, legend_constants) = createLegends()
    pylab.figure(1)
    pylab.plot(voi,vstack((states,algebraic)).T)
    pylab.xlabel(legend_voi)
    pylab.legend(legend_states + legend_algebraic, loc='best')
    pylab.show()

if __name__ == "__main__":
    (voi, states, algebraic) = solve_model()
    plot_model(voi, states, algebraic)