# Size of variable arrays: sizeAlgebraic = 56 sizeStates = 14 sizeConstants = 43 from math import * from numpy import * def createLegends(): legend_states = [""] * sizeStates legend_rates = [""] * sizeStates legend_algebraic = [""] * sizeAlgebraic legend_voi = "" legend_constants = [""] * sizeConstants legend_voi = "time in component environment (millisecond)" legend_states[0] = "Vm_n in component Vm_n (millivolt)" legend_algebraic[0] = "i_app in component Vm_n (nanoA_per_cm2)" legend_constants[0] = "Cm in component Vm_n (microF_per_cm2)" legend_constants[1] = "t0 in component Vm_n (millisecond)" legend_constants[2] = "t1 in component Vm_n (millisecond)" legend_algebraic[36] = "i_NaT in component i_NaT (nanoA_per_cm2)" legend_algebraic[38] = "i_NaP in component i_NaP (nanoA_per_cm2)" legend_algebraic[40] = "i_leakNa in component i_leakNa (nanoA_per_cm2)" legend_algebraic[25] = "i_KDR in component i_KDR (nanoA_per_cm2)" legend_algebraic[26] = "i_KA in component i_KA (nanoA_per_cm2)" legend_algebraic[27] = "i_leakK in component i_leakK (nanoA_per_cm2)" legend_algebraic[8] = "i_leakf in component i_leakf (nanoA_per_cm2)" legend_algebraic[34] = "i_NaKATPase_n in component i_NaKATPase_n (nanoA_per_cm2)" legend_algebraic[37] = "J_NaT in component i_NaT (picomole_per_cm2_millisecond)" legend_constants[3] = "gNaT in component i_NaT (microS_per_cm2)" legend_constants[4] = "F in component model_parameters (coulomb_per_mole)" legend_algebraic[35] = "ENa_n in component electric_potentials (millivolt)" legend_states[1] = "m in component i_NaT_m_gate (dimensionless)" legend_states[2] = "h in component i_NaT_h_gate (dimensionless)" legend_algebraic[1] = "alpha_m in component i_NaT_m_gate (per_millisecond)" legend_algebraic[9] = "beta_m in component i_NaT_m_gate (per_millisecond)" legend_algebraic[2] = "alpha_h in component i_NaT_h_gate (per_millisecond)" legend_algebraic[10] = "beta_h in component i_NaT_h_gate (per_millisecond)" legend_algebraic[39] = "J_NaP in component i_NaP (picomole_per_cm2_millisecond)" legend_constants[5] = "gNaP in component i_NaP (microS_per_cm2)" legend_states[3] = "m in component i_NaP_m_gate (dimensionless)" legend_states[4] = "h in component i_NaP_h_gate (dimensionless)" legend_algebraic[3] = "alpha_m in component i_NaP_m_gate (per_millisecond)" legend_algebraic[11] = "beta_m in component i_NaP_m_gate (per_millisecond)" legend_constants[6] = "tau_activation in component i_NaP_m_gate (millisecond)" legend_algebraic[4] = "alpha_h in component i_NaP_h_gate (per_millisecond)" legend_algebraic[12] = "beta_h in component i_NaP_h_gate (per_millisecond)" legend_algebraic[22] = "J_KDR in component i_KDR (picomole_per_cm2_millisecond)" legend_constants[7] = "gKDR in component i_KDR (microS_per_cm2)" legend_algebraic[21] = "EK_n in component electric_potentials (millivolt)" legend_states[5] = "n in component i_KDR_n_gate (dimensionless)" legend_algebraic[5] = "alpha_n in component i_KDR_n_gate (per_millisecond)" legend_algebraic[13] = "beta_n in component i_KDR_n_gate (per_millisecond)" legend_algebraic[23] = "J_KA in component i_KA (picomole_per_cm2_millisecond)" legend_constants[8] = "gKA in component i_KA (microS_per_cm2)" legend_states[6] = "m in component i_KA_m_gate (dimensionless)" legend_states[7] = "h in component i_KA_h_gate (dimensionless)" legend_algebraic[6] = "alpha_m in component i_KA_m_gate (per_millisecond)" legend_algebraic[14] = "beta_m in component i_KA_m_gate (per_millisecond)" legend_algebraic[7] = "alpha_h in component i_KA_h_gate (per_millisecond)" legend_algebraic[15] = "beta_h in component i_KA_h_gate (per_millisecond)" legend_algebraic[33] = "J_NaKATPase_n in component i_NaKATPase_n (picomole_per_cm2_millisecond)" legend_constants[9] = "I_NaKATPase_n_max in component i_NaKATPase_n (picomole_per_cm2_millisecond)" legend_constants[10] = "KmNa in component model_parameters (millimolar)" legend_constants[11] = "KmK in component model_parameters (millimolar)" legend_algebraic[32] = "Nan in component ion_concentrations (millimolar)" legend_algebraic[18] = "Ko in component ion_concentrations (millimolar)" legend_algebraic[41] = "J_leakNa in component i_leakNa (picomole_per_cm2_millisecond)" legend_constants[12] = "gleakNa in component i_leakNa (microS_per_cm2)" legend_algebraic[24] = "J_leakK in component i_leakK (picomole_per_cm2_millisecond)" legend_constants[13] = "gleakK in component i_leakK (microS_per_cm2)" legend_constants[14] = "gleakf in component i_leakf (microS_per_cm2)" legend_constants[15] = "Ef_n in component electric_potentials (millivolt)" legend_algebraic[50] = "Vm_g in component Vm_g (millivolt)" legend_algebraic[31] = "ENa_g in component electric_potentials (millivolt)" legend_algebraic[19] = "EK_g in component electric_potentials (millivolt)" legend_algebraic[49] = "ECl_g in component electric_potentials (millivolt)" legend_algebraic[45] = "ENBC_g in component electric_potentials (millivolt)" legend_constants[16] = "gNa in component J_Na (microS_per_cm2)" legend_constants[17] = "gK in component J_K (microS_per_cm2)" legend_constants[18] = "gCl in component model_parameters (microS_per_cm2)" legend_constants[19] = "gNBC in component J_NBC (microS_per_cm2)" legend_algebraic[29] = "J_NaKATPase_g in component J_NaKATPase_g (picomole_per_cm2_millisecond)" legend_algebraic[51] = "J_Na in component J_Na (picomole_per_cm2_millisecond)" legend_algebraic[52] = "J_K in component J_K (picomole_per_cm2_millisecond)" legend_constants[20] = "I_NaKATPase_g_max in component J_NaKATPase_g (picomole_per_cm2_millisecond)" legend_algebraic[28] = "Nag in component ion_concentrations (millimolar)" legend_algebraic[53] = "J_NBC in component J_NBC (picomole_per_cm2_millisecond)" legend_algebraic[48] = "J_NKCC1 in component J_NKCC1 (picomole_per_cm2_millisecond)" legend_constants[21] = "gNKCC1 in component J_NKCC1 (microS_per_cm2)" legend_constants[40] = "Psi in component model_parameters (millivolt)" legend_algebraic[30] = "Nao in component ion_concentrations (millimolar)" legend_constants[22] = "P_Ko in component ion_concentrations (millimolar)" legend_algebraic[17] = "Kg in component ion_concentrations (millimolar)" legend_algebraic[47] = "Clo in component ion_concentrations (millimolar)" legend_algebraic[46] = "Clg in component ion_concentrations (millimolar)" legend_states[8] = "N_Nag in component N_Nag (nanomole_per_cm2)" legend_algebraic[55] = "dN_Nag_dt in component N_Nag (nanomole_per_cm2_millisecond)" legend_states[9] = "N_Kg in component N_Kg (nanomole_per_cm2)" legend_algebraic[54] = "dN_Kg_dt in component N_Kg (nanomole_per_cm2_millisecond)" legend_states[10] = "wg in component wg (micrometre)" legend_constants[23] = "Lp in component model_parameters (cm_per_second_millimolar)" legend_constants[24] = "Xg in component model_parameters (millimolar_micrometre)" legend_algebraic[43] = "HCO3o in component ion_concentrations (millimolar)" legend_algebraic[44] = "HCO3g in component ion_concentrations (millimolar)" legend_algebraic[16] = "wo in component wo (micrometre)" legend_constants[25] = "P_wo in component model_parameters (micrometre)" legend_constants[26] = "P_wg in component model_parameters (micrometre)" legend_states[11] = "N_Nao in component N_Nao (nanomole_per_cm2)" legend_states[12] = "N_Ko in component N_Ko (nanomole_per_cm2)" legend_states[13] = "N_HCO3o in component N_HCO3o (nanomole_per_cm2)" legend_algebraic[20] = "Kn in component ion_concentrations (millimolar)" legend_algebraic[42] = "Cln in component ion_concentrations (millimolar)" legend_constants[27] = "P_Vm_g in component ion_concentrations (millivolt)" legend_constants[39] = "P_Clo in component ion_concentrations (millimolar)" legend_constants[28] = "P_Cln in component ion_concentrations (millimolar)" legend_constants[41] = "P_Clg in component ion_concentrations (millimolar)" legend_constants[29] = "P_Nan in component ion_concentrations (millimolar)" legend_constants[30] = "P_Nao in component ion_concentrations (millimolar)" legend_constants[31] = "P_Nag in component ion_concentrations (millimolar)" legend_constants[32] = "P_Kn in component ion_concentrations (millimolar)" legend_constants[33] = "P_Kg in component ion_concentrations (millimolar)" legend_constants[42] = "P_HCO3g in component ion_concentrations (millimolar)" legend_constants[34] = "P_HCO3o in component ion_concentrations (millimolar)" legend_constants[35] = "P_wn in component ion_concentrations (micrometre)" legend_constants[36] = "rho in component model_parameters (dimensionless)" legend_constants[37] = "R in component model_parameters (joule_per_mole_kelvin)" legend_constants[38] = "T in component model_parameters (kelvin)" legend_rates[0] = "d/dt Vm_n in component Vm_n (millivolt)" legend_rates[1] = "d/dt m in component i_NaT_m_gate (dimensionless)" legend_rates[2] = "d/dt h in component i_NaT_h_gate (dimensionless)" legend_rates[3] = "d/dt m in component i_NaP_m_gate (dimensionless)" legend_rates[4] = "d/dt h in component i_NaP_h_gate (dimensionless)" legend_rates[5] = "d/dt n in component i_KDR_n_gate (dimensionless)" legend_rates[6] = "d/dt m in component i_KA_m_gate (dimensionless)" legend_rates[7] = "d/dt h in component i_KA_h_gate (dimensionless)" legend_rates[8] = "d/dt N_Nag in component N_Nag (nanomole_per_cm2)" legend_rates[9] = "d/dt N_Kg in component N_Kg (nanomole_per_cm2)" legend_rates[10] = "d/dt wg in component wg (micrometre)" legend_rates[11] = "d/dt N_Nao in component N_Nao (nanomole_per_cm2)" legend_rates[12] = "d/dt N_Ko in component N_Ko (nanomole_per_cm2)" legend_rates[13] = "d/dt N_HCO3o in component N_HCO3o (nanomole_per_cm2)" return (legend_states, legend_algebraic, legend_voi, legend_constants) def initConsts(): constants = [0.0] * sizeConstants; states = [0.0] * sizeStates; states[0] = -70 constants[0] = 1 constants[1] = 100 constants[2] = 700 constants[3] = 5000 constants[4] = 9.649e4 states[1] = 0.005 states[2] = 0.9961 constants[5] = 150 states[3] = 0.0129 states[4] = 0.9718 constants[6] = 6 constants[7] = 5000 states[5] = 0.0012 constants[8] = 1000 states[6] = 0.1193 states[7] = 0.1205 constants[9] = 0.0289 constants[10] = 10 constants[11] = 1.5 constants[12] = 20 constants[13] = 66.06 constants[14] = 10 constants[15] = -70 constants[16] = 100.0 constants[17] = 1696.0 constants[18] = 50 constants[19] = 80 constants[20] = 0.1151 constants[21] = 2 constants[22] = 3 states[8] = 0.75 states[9] = 5 states[10] = 0.05 constants[23] = 2e-8 constants[24] = 8.45 constants[25] = 0.025 constants[26] = 0.05 states[11] = 3.65 states[12] = 0.075 states[13] = 0.375 constants[27] = -85 constants[28] = 50 constants[29] = 10 constants[30] = 146 constants[31] = 15 constants[32] = 130 constants[33] = 100 constants[34] = 15 constants[35] = 0.05 constants[36] = 0.5975 constants[37] = 8.315 constants[38] = 300 constants[39] = (constants[30]+constants[22])-constants[34] constants[40] = (1000.00*constants[37]*constants[38])/constants[4] constants[41] = constants[39]*exp(constants[27]/constants[40]) constants[42] = constants[34]*(power((constants[30]/constants[31])*exp(constants[27]/constants[40]), 1.0/2)) return (states, constants) def computeRates(voi, states, constants): rates = [0.0] * sizeStates; algebraic = [0.0] * sizeAlgebraic algebraic[1] = (0.320000*(-states[0]-51.9000))/(exp(-(0.250000*states[0]+12.9750))-1.00000) algebraic[9] = (0.280000*(states[0]+24.8900))/(exp(0.200000*states[0]+4.97800)-1.00000) rates[1] = algebraic[1]*(1.00000-states[1])-algebraic[9]*states[1] algebraic[2] = 0.128000*exp(-(0.0560000*states[0]+2.94000)) algebraic[10] = 4.00000/(exp(-(0.200000*states[0]+6.00000))+1.00000) rates[2] = algebraic[2]*(1.00000-states[2])-algebraic[10]*states[2] algebraic[3] = ((1.00000/constants[6])*1.00000)/(exp(-(0.143000*states[0]+5.67000))+1.00000) algebraic[11] = ((1.00000/constants[6])*exp(-(0.143000*states[0]+5.67000)))/(exp(-(0.143000*states[0]+5.67000))+1.00000) rates[3] = algebraic[3]*(1.00000-states[3])-algebraic[11]*states[3] algebraic[4] = 5.12000e-08*exp(-(0.0560000*states[0]+2.94000)) algebraic[12] = 1.60000e-06/(exp(-(0.200000*states[0]+8.00000))+1.00000) rates[4] = algebraic[4]*(1.00000-states[4])-algebraic[12]*states[4] algebraic[5] = (0.0160000*(-states[0]-34.9000))/(exp(-(0.200000*states[0]+6.98000))-1.00000) algebraic[13] = 0.250000*exp(-(0.0250000*states[0]+1.25000)) rates[5] = algebraic[5]*(1.00000-states[5])-algebraic[13]*states[5] algebraic[6] = (0.0200000*(-states[0]-56.9000))/(exp(-(0.100000*states[0]+5.69000))-1.00000) algebraic[14] = (0.0175000*(states[0]+29.9000))/(exp(0.100000*states[0]+2.99000)-1.00000) rates[6] = algebraic[6]*(1.00000-states[6])-algebraic[14]*states[6] algebraic[7] = 0.0160000*exp(-(0.0560000*states[0]+4.61000)) algebraic[15] = 0.500000/(exp(-(0.200000*states[0]+11.9800))+1.00000) rates[7] = algebraic[7]*(1.00000-states[7])-algebraic[15]*states[7] algebraic[0] = custom_piecewise([greater_equal(voi , constants[1]) & less_equal(voi , constants[2]), 3500.00 , True, 0.00000]) algebraic[32] = ((constants[35]*constants[29]+constants[26]*constants[31]+constants[25]*constants[30])-(states[11]+states[8]))/constants[35] algebraic[16] = (constants[26]+constants[25])-states[10] algebraic[30] = states[11]/algebraic[16] algebraic[35] = constants[40]*log(algebraic[30]/algebraic[32]) algebraic[36] = constants[3]*(power(states[1], 3.00000))*states[2]*(states[0]-algebraic[35]) algebraic[38] = constants[5]*(power(states[3], 2.00000))*states[4]*(states[0]-algebraic[35]) algebraic[40] = constants[12]*(states[0]-algebraic[35]) algebraic[18] = states[12]/algebraic[16] algebraic[20] = ((constants[35]*constants[32]+constants[26]*constants[33]+constants[25]*constants[22])-(states[12]+states[9]))/constants[35] algebraic[21] = constants[40]*log(algebraic[18]/algebraic[20]) algebraic[25] = constants[7]*(power(states[5], 2.00000))*(states[0]-algebraic[21]) algebraic[26] = constants[8]*(power(states[6], 2.00000))*states[7]*(states[0]-algebraic[21]) algebraic[27] = constants[13]*(states[0]-algebraic[21]) algebraic[8] = constants[14]*(states[0]-constants[15]) algebraic[33] = (((constants[9]*(power(algebraic[32], 1.50000)))/(power(algebraic[32], 1.50000)+power(constants[10], 1.50000)))*algebraic[18])/(algebraic[18]+constants[11]) algebraic[34] = algebraic[33]*constants[4] rates[0] = (0.00100000*(-(algebraic[36]+algebraic[38]+algebraic[40]+algebraic[25]+algebraic[26]+algebraic[27]+algebraic[8]+algebraic[34])+algebraic[0]))/constants[0] algebraic[28] = states[8]/states[10] algebraic[17] = states[9]/states[10] algebraic[44] = ((constants[26]*constants[42]+constants[25]*constants[34])-states[13])/states[10] algebraic[46] = (algebraic[28]+algebraic[17])-(algebraic[44]+(constants[36]*constants[24])/states[10]) algebraic[42] = ((constants[28]+algebraic[32])-constants[29])+(algebraic[20]-constants[32]) algebraic[47] = ((constants[26]*constants[41]+constants[25]*constants[39]+constants[35]*constants[28])-(states[10]*algebraic[46]+constants[35]*algebraic[42]))/algebraic[16] algebraic[43] = states[13]/algebraic[16] rates[10] = 10.0000*constants[23]*((algebraic[28]+algebraic[17]+algebraic[46]+algebraic[44]+constants[24]/states[10])-(algebraic[30]+algebraic[18]+algebraic[47]+algebraic[43])) algebraic[29] = (((constants[20]*(power(algebraic[28], 1.50000)))/(power(algebraic[28], 1.50000)+power(constants[10], 1.50000)))*algebraic[18])/(algebraic[18]+constants[11]) algebraic[31] = constants[40]*log(algebraic[30]/algebraic[28]) algebraic[19] = constants[40]*log(algebraic[18]/algebraic[17]) algebraic[49] = -1.00000*constants[40]*log(algebraic[47]/algebraic[46]) algebraic[45] = -constants[40]*log((algebraic[30]/algebraic[28])*(power(algebraic[43]/algebraic[44], 2.00000))) algebraic[50] = (constants[16]*algebraic[31]+constants[17]*algebraic[19]+constants[18]*algebraic[49]+constants[19]*algebraic[45])/(constants[16]+constants[17]+constants[18]+constants[19])-(constants[4]*algebraic[29])/(constants[16]+constants[17]+constants[18]+constants[19]) algebraic[52] = (constants[17]*(algebraic[50]-algebraic[19]))/constants[4] algebraic[48] = custom_piecewise([greater(algebraic[18] , constants[22]), (((power(algebraic[18]-constants[22], 10.0000))/(power(algebraic[18]-constants[22], 10.0000)+power(0.0300000, 10.0000)))*constants[40]*constants[21]*log((((algebraic[18]/algebraic[17])*algebraic[30])/algebraic[28])*(power(algebraic[47]/algebraic[46], 2.00000))))/constants[4] , True, 0.00000]) algebraic[54] = 0.0100000*(-algebraic[52]+2.00000*algebraic[29]+algebraic[48]) rates[9] = algebraic[54] algebraic[37] = (constants[3]*(power(states[1], 3.00000))*states[2]*(states[0]-algebraic[35]))/constants[4] algebraic[39] = (constants[5]*(power(states[3], 2.00000))*states[4]*(states[0]-algebraic[35]))/constants[4] algebraic[41] = (constants[12]*(states[0]-algebraic[35]))/constants[4] rates[12] = -0.0100000*(algebraic[37]+algebraic[39]+algebraic[41]+3.00000*algebraic[33])-algebraic[54] algebraic[53] = (constants[19]*(algebraic[50]-algebraic[45]))/constants[4] rates[13] = -0.0100000*2.00000*algebraic[53] algebraic[51] = (constants[16]*(algebraic[50]-algebraic[31]))/constants[4] algebraic[55] = 0.0100000*((-algebraic[51]-3.00000*algebraic[29])+algebraic[48]+algebraic[53]) rates[8] = algebraic[55] rates[11] = 0.0100000*((3.00000*algebraic[33]+algebraic[37]+algebraic[39]+algebraic[41])-100.000*algebraic[55]) return(rates) def computeAlgebraic(constants, states, voi): algebraic = array([[0.0] * len(voi)] * sizeAlgebraic) states = array(states) voi = array(voi) algebraic[1] = (0.320000*(-states[0]-51.9000))/(exp(-(0.250000*states[0]+12.9750))-1.00000) algebraic[9] = (0.280000*(states[0]+24.8900))/(exp(0.200000*states[0]+4.97800)-1.00000) algebraic[2] = 0.128000*exp(-(0.0560000*states[0]+2.94000)) algebraic[10] = 4.00000/(exp(-(0.200000*states[0]+6.00000))+1.00000) algebraic[3] = ((1.00000/constants[6])*1.00000)/(exp(-(0.143000*states[0]+5.67000))+1.00000) algebraic[11] = ((1.00000/constants[6])*exp(-(0.143000*states[0]+5.67000)))/(exp(-(0.143000*states[0]+5.67000))+1.00000) algebraic[4] = 5.12000e-08*exp(-(0.0560000*states[0]+2.94000)) algebraic[12] = 1.60000e-06/(exp(-(0.200000*states[0]+8.00000))+1.00000) algebraic[5] = (0.0160000*(-states[0]-34.9000))/(exp(-(0.200000*states[0]+6.98000))-1.00000) algebraic[13] = 0.250000*exp(-(0.0250000*states[0]+1.25000)) algebraic[6] = (0.0200000*(-states[0]-56.9000))/(exp(-(0.100000*states[0]+5.69000))-1.00000) algebraic[14] = (0.0175000*(states[0]+29.9000))/(exp(0.100000*states[0]+2.99000)-1.00000) algebraic[7] = 0.0160000*exp(-(0.0560000*states[0]+4.61000)) algebraic[15] = 0.500000/(exp(-(0.200000*states[0]+11.9800))+1.00000) algebraic[0] = custom_piecewise([greater_equal(voi , constants[1]) & less_equal(voi , constants[2]), 3500.00 , True, 0.00000]) algebraic[32] = ((constants[35]*constants[29]+constants[26]*constants[31]+constants[25]*constants[30])-(states[11]+states[8]))/constants[35] algebraic[16] = (constants[26]+constants[25])-states[10] algebraic[30] = states[11]/algebraic[16] algebraic[35] = constants[40]*log(algebraic[30]/algebraic[32]) algebraic[36] = constants[3]*(power(states[1], 3.00000))*states[2]*(states[0]-algebraic[35]) algebraic[38] = constants[5]*(power(states[3], 2.00000))*states[4]*(states[0]-algebraic[35]) algebraic[40] = constants[12]*(states[0]-algebraic[35]) algebraic[18] = states[12]/algebraic[16] algebraic[20] = ((constants[35]*constants[32]+constants[26]*constants[33]+constants[25]*constants[22])-(states[12]+states[9]))/constants[35] algebraic[21] = constants[40]*log(algebraic[18]/algebraic[20]) algebraic[25] = constants[7]*(power(states[5], 2.00000))*(states[0]-algebraic[21]) algebraic[26] = constants[8]*(power(states[6], 2.00000))*states[7]*(states[0]-algebraic[21]) algebraic[27] = constants[13]*(states[0]-algebraic[21]) algebraic[8] = constants[14]*(states[0]-constants[15]) algebraic[33] = (((constants[9]*(power(algebraic[32], 1.50000)))/(power(algebraic[32], 1.50000)+power(constants[10], 1.50000)))*algebraic[18])/(algebraic[18]+constants[11]) algebraic[34] = algebraic[33]*constants[4] algebraic[28] = states[8]/states[10] algebraic[17] = states[9]/states[10] algebraic[44] = ((constants[26]*constants[42]+constants[25]*constants[34])-states[13])/states[10] algebraic[46] = (algebraic[28]+algebraic[17])-(algebraic[44]+(constants[36]*constants[24])/states[10]) algebraic[42] = ((constants[28]+algebraic[32])-constants[29])+(algebraic[20]-constants[32]) algebraic[47] = ((constants[26]*constants[41]+constants[25]*constants[39]+constants[35]*constants[28])-(states[10]*algebraic[46]+constants[35]*algebraic[42]))/algebraic[16] algebraic[43] = states[13]/algebraic[16] algebraic[29] = (((constants[20]*(power(algebraic[28], 1.50000)))/(power(algebraic[28], 1.50000)+power(constants[10], 1.50000)))*algebraic[18])/(algebraic[18]+constants[11]) algebraic[31] = constants[40]*log(algebraic[30]/algebraic[28]) algebraic[19] = constants[40]*log(algebraic[18]/algebraic[17]) algebraic[49] = -1.00000*constants[40]*log(algebraic[47]/algebraic[46]) algebraic[45] = -constants[40]*log((algebraic[30]/algebraic[28])*(power(algebraic[43]/algebraic[44], 2.00000))) algebraic[50] = (constants[16]*algebraic[31]+constants[17]*algebraic[19]+constants[18]*algebraic[49]+constants[19]*algebraic[45])/(constants[16]+constants[17]+constants[18]+constants[19])-(constants[4]*algebraic[29])/(constants[16]+constants[17]+constants[18]+constants[19]) algebraic[52] = (constants[17]*(algebraic[50]-algebraic[19]))/constants[4] algebraic[48] = custom_piecewise([greater(algebraic[18] , constants[22]), (((power(algebraic[18]-constants[22], 10.0000))/(power(algebraic[18]-constants[22], 10.0000)+power(0.0300000, 10.0000)))*constants[40]*constants[21]*log((((algebraic[18]/algebraic[17])*algebraic[30])/algebraic[28])*(power(algebraic[47]/algebraic[46], 2.00000))))/constants[4] , True, 0.00000]) algebraic[54] = 0.0100000*(-algebraic[52]+2.00000*algebraic[29]+algebraic[48]) algebraic[37] = (constants[3]*(power(states[1], 3.00000))*states[2]*(states[0]-algebraic[35]))/constants[4] algebraic[39] = (constants[5]*(power(states[3], 2.00000))*states[4]*(states[0]-algebraic[35]))/constants[4] algebraic[41] = (constants[12]*(states[0]-algebraic[35]))/constants[4] algebraic[53] = (constants[19]*(algebraic[50]-algebraic[45]))/constants[4] algebraic[51] = (constants[16]*(algebraic[50]-algebraic[31]))/constants[4] algebraic[55] = 0.0100000*((-algebraic[51]-3.00000*algebraic[29])+algebraic[48]+algebraic[53]) algebraic[22] = (constants[7]*(power(states[5], 2.00000))*(states[0]-algebraic[21]))/constants[4] algebraic[23] = (constants[8]*(power(states[6], 2.00000))*states[7]*(states[0]-algebraic[21]))/constants[4] algebraic[24] = (constants[13]*(states[0]-algebraic[21]))/constants[4] return algebraic def custom_piecewise(cases): """Compute result of a piecewise function""" return select(cases[0::2],cases[1::2]) def solve_model(): """Solve model with ODE solver""" from scipy.integrate import ode # Initialise constants and state variables (init_states, constants) = initConsts() # Set timespan to solve over voi = linspace(0, 10, 500) # Construct ODE object to solve r = ode(computeRates) r.set_integrator('vode', method='bdf', atol=1e-06, rtol=1e-06, max_step=1) r.set_initial_value(init_states, voi[0]) r.set_f_params(constants) # Solve model states = array([[0.0] * len(voi)] * sizeStates) states[:,0] = init_states for (i,t) in enumerate(voi[1:]): if r.successful(): r.integrate(t) states[:,i+1] = r.y else: break # Compute algebraic variables algebraic = computeAlgebraic(constants, states, voi) return (voi, states, algebraic) def plot_model(voi, states, algebraic): """Plot variables against variable of integration""" import pylab (legend_states, legend_algebraic, legend_voi, legend_constants) = createLegends() pylab.figure(1) pylab.plot(voi,vstack((states,algebraic)).T) pylab.xlabel(legend_voi) pylab.legend(legend_states + legend_algebraic, loc='best') pylab.show() if __name__ == "__main__": (voi, states, algebraic) = solve_model() plot_model(voi, states, algebraic)