C C There are a total of 8 entries in the algebraic variable array. C There are a total of 3 entries in each of the rate and state variable arrays. C There are a total of 22 entries in the constant variable array. C C C VOI is time in component environment (ms). C ALGBRC(2) is Istim in component stimulus_protocol (per_ms). C CONSTS(1) is IstimStart in component stimulus_protocol (ms). C CONSTS(2) is IstimEnd in component stimulus_protocol (ms). C CONSTS(3) is IstimAmplitude in component stimulus_protocol (per_ms). C CONSTS(4) is IstimPeriod in component stimulus_protocol (ms). C CONSTS(5) is IstimPulseDuration in component stimulus_protocol (ms). C STATES(1) is u in component membrane (dimensionless). C CONSTS(6) is Cm in component membrane (uF_per_cm2). C ALGBRC(1) is Vm in component membrane (mV). C CONSTS(7) is V_0 in component membrane (mV). C CONSTS(8) is V_fi in component membrane (mV). C ALGBRC(4) is J_fi in component fast_inward_current (per_ms). C ALGBRC(6) is J_so in component slow_outward_current (per_ms). C ALGBRC(8) is J_si in component slow_inward_current (per_ms). C ALGBRC(3) is p in component p (dimensionless). C CONSTS(9) is u_c in component p (dimensionless). C ALGBRC(5) is q in component q (dimensionless). C CONSTS(10) is u_v in component q (dimensionless). C CONSTS(22) is tau_d in component fast_inward_current (ms). C CONSTS(11) is g_fi_max in component fast_inward_current (mS_per_cm2). C STATES(2) is v in component fast_inward_current_v_gate (dimensionless). C ALGBRC(7) is tau_v_minus in component fast_inward_current_v_gate (ms). C CONSTS(12) is tau_v1_minus in component fast_inward_current_v_gate (ms). C CONSTS(13) is tau_v2_minus in component fast_inward_current_v_gate (ms). C CONSTS(14) is tau_v_plus in component fast_inward_current_v_gate (ms). C CONSTS(15) is tau_0 in component slow_outward_current (ms). C CONSTS(16) is tau_r in component slow_outward_current (ms). C CONSTS(17) is tau_si in component slow_inward_current (ms). C CONSTS(18) is u_csi in component slow_inward_current (dimensionless). C CONSTS(19) is k in component slow_inward_current (dimensionless). C STATES(3) is w in component slow_inward_current_w_gate (dimensionless). C CONSTS(20) is tau_w_minus in component slow_inward_current_w_gate (ms). C CONSTS(21) is tau_w_plus in component slow_inward_current_w_gate (ms). C RATES(1) is d/dt u in component membrane (dimensionless). C RATES(2) is d/dt v in component fast_inward_current_v_gate (dimensionless). C RATES(3) is d/dt w in component slow_inward_current_w_gate (dimensionless). C SUBROUTINE initConsts(CONSTS, RATES, STATES) REAL CONSTS(*), RATES(*), STATES(*) CONSTS(1) = 100 CONSTS(2) = 50000 CONSTS(3) = -0.2 CONSTS(4) = 1000 CONSTS(5) = 1 STATES(1) = 0 CONSTS(6) = 1 CONSTS(7) = -85 CONSTS(8) = 15 CONSTS(9) = 0.13 CONSTS(10) = 0 CONSTS(11) = 5.8 STATES(2) = 1 CONSTS(12) = 18.2 CONSTS(13) = 18.2 CONSTS(14) = 10 CONSTS(15) = 12.5 CONSTS(16) = 130 CONSTS(17) = 127 CONSTS(18) = 0.85 CONSTS(19) = 10 STATES(3) = 1 CONSTS(20) = 80 CONSTS(21) = 1020 CONSTS(22) = CONSTS(6)/CONSTS(11) RETURN END SUBROUTINE computeRates(VOI, CONSTS, RATES, STATES, ALGBRC) REAL VOI, CONSTS(*), RATES(*), STATES(*), ALGBRC(*) ALGBRC(3) = TERNRY(STATES(1).LT.CONSTS(9), 0.00000, 1.00000) RATES(3) = ( (1.00000 - ALGBRC(3))*(1.00000 - STATES(3)))/CONSTS(20) - ( ALGBRC(3)*STATES(3))/CONSTS(21) ALGBRC(5) = TERNRY(STATES(1).LT.CONSTS(10), 0.00000, 1.00000) ALGBRC(7) = ALGBRC(5)*CONSTS(12)+ (1.00000 - ALGBRC(5))*CONSTS(13) RATES(2) = ( (1.00000 - ALGBRC(3))*(1.00000 - STATES(2)))/ALGBRC(7) - ( ALGBRC(3)*STATES(2))/CONSTS(14) ALGBRC(2) = TERNRY(VOI.GE.CONSTS(1).AND.VOI.LE.CONSTS(2).AND.(VOI - CONSTS(1)) - INT((VOI - CONSTS(1))/CONSTS(4))*CONSTS(4).LE.CONSTS(5), CONSTS(3), 0.00000) ALGBRC(4) = ( - STATES(2)*ALGBRC(3)*(1.00000 - STATES(1))*(STATES(1) - CONSTS(9)))/CONSTS(22) ALGBRC(6) = ( STATES(1)*(1.00000 - ALGBRC(3)))/CONSTS(15)+ALGBRC(3)/CONSTS(16) ALGBRC(8) = ( - STATES(3)*(1.00000+ tanh( CONSTS(19)*(STATES(1) - CONSTS(18)))))/( 2.00000*CONSTS(17)) RATES(1) = - (ALGBRC(4)+ALGBRC(6)+ALGBRC(8)+ALGBRC(2)) RETURN END SUBROUTINE computeVariables(VOI, CONSTS, RATES, STATES, ALGBRC) REAL VOI, CONSTS(*), RATES(*), STATES(*), ALGBRC(*) ALGBRC(3) = TERNRY(STATES(1).LT.CONSTS(9), 0.00000, 1.00000) ALGBRC(5) = TERNRY(STATES(1).LT.CONSTS(10), 0.00000, 1.00000) ALGBRC(7) = ALGBRC(5)*CONSTS(12)+ (1.00000 - ALGBRC(5))*CONSTS(13) ALGBRC(2) = TERNRY(VOI.GE.CONSTS(1).AND.VOI.LE.CONSTS(2).AND.(VOI - CONSTS(1)) - INT((VOI - CONSTS(1))/CONSTS(4))*CONSTS(4).LE.CONSTS(5), CONSTS(3), 0.00000) ALGBRC(4) = ( - STATES(2)*ALGBRC(3)*(1.00000 - STATES(1))*(STATES(1) - CONSTS(9)))/CONSTS(22) ALGBRC(6) = ( STATES(1)*(1.00000 - ALGBRC(3)))/CONSTS(15)+ALGBRC(3)/CONSTS(16) ALGBRC(8) = ( - STATES(3)*(1.00000+ tanh( CONSTS(19)*(STATES(1) - CONSTS(18)))))/( 2.00000*CONSTS(17)) ALGBRC(1) = CONSTS(7)+ STATES(1)*(CONSTS(8) - CONSTS(7)) RETURN END REAL FUNCTION TERNRY(TEST, VALA, VALB) LOGICAL TEST REAL VALA, VALB IF (TEST) THEN TERNRY = VALA ELSE TERNRY = VALB ENDIF RETURN END