Generated Code
The following is c_ida code generated by the CellML API from this CellML file. (Back to language selection)
The raw code is available.
/*
There are a total of 90 entries in the algebraic variable array.
There are a total of 31 entries in each of the rate and state variable arrays.
There are a total of 133 entries in the constant variable array.
*/
/*
* VOI is time in component environment (second).
* CONSTANTS[0] is isotonic in component parameters (dimensionless).
* CONSTANTS[1] is alpha_1 in component parameters (per_micrometre).
* CONSTANTS[2] is beta_1 in component parameters (millinewton).
* CONSTANTS[3] is alpha_2 in component parameters (per_micrometre).
* CONSTANTS[4] is beta_2 in component parameters (millinewton).
* CONSTANTS[5] is alpha_3 in component parameters (per_micrometre).
* CONSTANTS[6] is beta_3 in component parameters (millinewton).
* CONSTANTS[7] is lambda in component parameters (millinewton).
* CONSTANTS[8] is mu in component parameters (dimensionless).
* CONSTANTS[9] is k_mu in component parameters (dimensionless).
* CONSTANTS[10] is kappa in component parameters (dimensionless).
* CONSTANTS[11] is kappa_0 in component parameters (dimensionless).
* CONSTANTS[12] is m_0 in component parameters (dimensionless).
* CONSTANTS[13] is v_max in component parameters (micrometre_per_second).
* CONSTANTS[14] is a in component parameters (dimensionless).
* CONSTANTS[15] is d_h in component parameters (dimensionless).
* CONSTANTS[16] is alpha_P in component parameters (dimensionless).
* ALGEBRAIC[7] is l in component length (micrometre).
* ALGEBRAIC[81] is F_muscle in component force (millinewton).
* CONSTANTS[17] is F_afterload in component isotonic (millinewton).
* ALGEBRAIC[85] is isotonic_mode in component isotonic (dimensionless).
* CONSTANTS[18] is l_0 in component length (micrometre).
* CONSTANTS[19] is stim_period in component membrane (second).
* CONSTANTS[20] is S_0 in component parameters_izakov_et_al_1991 (micrometre).
* ALGEBRAIC[0] is q_v in component parameters_izakov_et_al_1991 (per_second).
* CONSTANTS[21] is q_1 in component parameters_izakov_et_al_1991 (per_second).
* CONSTANTS[22] is q_2 in component parameters_izakov_et_al_1991 (per_second).
* CONSTANTS[23] is q_3 in component parameters_izakov_et_al_1991 (per_second).
* CONSTANTS[24] is q_4 in component parameters_izakov_et_al_1991 (per_second).
* CONSTANTS[25] is x_st in component parameters_izakov_et_al_1991 (dimensionless).
* CONSTANTS[123] is v_st in component parameters_izakov_et_al_1991 (micrometre_per_second).
* CONSTANTS[124] is v_1 in component parameters_izakov_et_al_1991 (micrometre_per_second).
* CONSTANTS[26] is alpha_G in component parameters_izakov_et_al_1991 (dimensionless).
* CONSTANTS[27] is k_A in component parameters_izakov_et_al_1991 (per_millimolar).
* STATES[0] is v in component CE_velocity (micrometre_per_second).
* CONSTANTS[28] is alpha_Q in component parameters_izakov_et_al_1991 (dimensionless).
* CONSTANTS[29] is beta_Q in component parameters_izakov_et_al_1991 (dimensionless).
* ALGEBRAIC[80] is F_CE in component force (millinewton).
* ALGEBRAIC[3] is F_XSE in component force (millinewton).
* ALGEBRAIC[1] is F_SE in component force (millinewton).
* ALGEBRAIC[2] is F_PE in component force (millinewton).
* STATES[1] is N in component crossbridge_kinetics (dimensionless).
* ALGEBRAIC[10] is k_P_vis in component CE_velocity (millinewton_second_per_micrometre).
* ALGEBRAIC[12] is k_S_vis in component PE_velocity (millinewton_second_per_micrometre).
* STATES[2] is w in component PE_velocity (micrometre_per_second).
* STATES[3] is l_1 in component length (micrometre).
* STATES[4] is l_2 in component length (micrometre).
* STATES[5] is l_3 in component length (micrometre).
* ALGEBRAIC[17] is p_v in component average_crossbridge_force (dimensionless).
* ALGEBRAIC[84] is K_kappa in component crossbridge_kinetics (per_second).
* ALGEBRAIC[4] is M_A in component crossbridge_kinetics (dimensionless).
* ALGEBRAIC[5] is n_1 in component crossbridge_kinetics (dimensionless).
* ALGEBRAIC[6] is L_oz in component crossbridge_kinetics (dimensionless).
* ALGEBRAIC[82] is k_p_v in component crossbridge_kinetics (per_second).
* ALGEBRAIC[83] is k_m_v in component crossbridge_kinetics (per_second).
* STATES[6] is A in component intracellular_calcium_concentration (millimolar).
* CONSTANTS[30] is A_tot in component intracellular_calcium_concentration (millimolar).
* ALGEBRAIC[14] is G_star in component average_crossbridge_force (dimensionless).
* ALGEBRAIC[13] is P_star in component average_crossbridge_force (dimensionless).
* CONSTANTS[31] is g_1 in component crossbridge_kinetics (per_micrometre).
* CONSTANTS[32] is g_2 in component crossbridge_kinetics (dimensionless).
* ALGEBRAIC[8] is dl_1_dt in component length (micrometre_per_second).
* ALGEBRAIC[88] is dl_2_dt in component length (micrometre_per_second).
* ALGEBRAIC[89] is dl_3_dt in component length (micrometre_per_second).
* ALGEBRAIC[87] is phi_chi_2 in component CE_velocity (micrometre_per_second).
* CONSTANTS[33] is stim_start in component membrane (second).
* CONSTANTS[34] is stim_end in component membrane (second).
* CONSTANTS[35] is stim_duration in component membrane (second).
* CONSTANTS[36] is stim_amplitude in component membrane (nanoA).
* ALGEBRAIC[86] is phi_chi in component CE_velocity (micrometre_per_second2).
* ALGEBRAIC[18] is p_prime_v in component average_crossbridge_force (second_per_micrometre).
* CONSTANTS[37] is alpha_P_lengthening in component CE_velocity (per_micrometre).
* CONSTANTS[38] is beta_P_lengthening in component CE_velocity (millinewton_second_per_micrometre).
* CONSTANTS[39] is alpha_P_shortening in component CE_velocity (per_micrometre).
* CONSTANTS[40] is beta_P_shortening in component CE_velocity (millinewton_second_per_micrometre).
* ALGEBRAIC[9] is alp_p in component CE_velocity (per_micrometre).
* CONSTANTS[41] is alpha_S_lengthening in component PE_velocity (per_micrometre).
* CONSTANTS[42] is beta_S_lengthening in component PE_velocity (millinewton_second_per_micrometre).
* CONSTANTS[43] is alpha_S_shortening in component PE_velocity (per_micrometre).
* CONSTANTS[44] is beta_S_shortening in component PE_velocity (millinewton_second_per_micrometre).
* ALGEBRAIC[11] is alp_s in component PE_velocity (per_micrometre).
* CONSTANTS[130] is gamma in component average_crossbridge_force (dimensionless).
* CONSTANTS[125] is case_1 in component average_crossbridge_force (second_per_micrometre).
* ALGEBRAIC[15] is case_2 in component average_crossbridge_force (second_per_micrometre).
* CONSTANTS[126] is case_3 in component average_crossbridge_force (second_per_micrometre).
* ALGEBRAIC[16] is case_4 in component average_crossbridge_force (second_per_micrometre).
* STATES[7] is V in component membrane (millivolt).
* CONSTANTS[45] is R in component membrane (joule_per_kilomole_kelvin).
* CONSTANTS[46] is T in component membrane (kelvin).
* CONSTANTS[47] is F in component membrane (coulomb_per_mole).
* CONSTANTS[48] is Cm in component membrane (microF).
* ALGEBRAIC[25] is i_K1 in component time_independent_potassium_current (nanoA).
* ALGEBRAIC[57] is i_to in component transient_outward_current (nanoA).
* ALGEBRAIC[26] is i_Kr in component rapid_delayed_rectifier_potassium_current (nanoA).
* ALGEBRAIC[31] is i_Ks in component slow_delayed_rectifier_potassium_current (nanoA).
* ALGEBRAIC[44] is i_Ca_L_K_cyt in component L_type_Ca_channel (nanoA).
* ALGEBRAIC[47] is i_Ca_L_K_ds in component L_type_Ca_channel (nanoA).
* ALGEBRAIC[60] is i_NaK in component sodium_potassium_pump (nanoA).
* ALGEBRAIC[35] is i_Na in component fast_sodium_current (nanoA).
* ALGEBRAIC[42] is i_b_Na in component sodium_background_current (nanoA).
* ALGEBRAIC[41] is i_p_Na in component persistent_sodium_current (nanoA).
* ALGEBRAIC[45] is i_Ca_L_Na_cyt in component L_type_Ca_channel (nanoA).
* ALGEBRAIC[48] is i_Ca_L_Na_ds in component L_type_Ca_channel (nanoA).
* ALGEBRAIC[61] is i_NaCa_cyt in component sodium_calcium_exchanger (nanoA).
* ALGEBRAIC[62] is i_NaCa_ds in component sodium_calcium_exchanger (nanoA).
* ALGEBRAIC[43] is i_Ca_L_Ca_cyt in component L_type_Ca_channel (nanoA).
* ALGEBRAIC[46] is i_Ca_L_Ca_ds in component L_type_Ca_channel (nanoA).
* ALGEBRAIC[56] is i_b_Ca in component calcium_background_current (nanoA).
* ALGEBRAIC[19] is i_Stim in component membrane (nanoA).
* ALGEBRAIC[20] is E_Na in component reversal_potentials (millivolt).
* ALGEBRAIC[21] is E_K in component reversal_potentials (millivolt).
* ALGEBRAIC[22] is E_Ks in component reversal_potentials (millivolt).
* ALGEBRAIC[23] is E_Ca in component reversal_potentials (millivolt).
* ALGEBRAIC[24] is E_mh in component reversal_potentials (millivolt).
* CONSTANTS[49] is P_kna in component reversal_potentials (dimensionless).
* STATES[8] is K_o in component extracellular_potassium_concentration (millimolar).
* CONSTANTS[50] is Na_o in component extracellular_sodium_concentration (millimolar).
* STATES[9] is K_i in component intracellular_potassium_concentration (millimolar).
* STATES[10] is Na_i in component intracellular_sodium_concentration (millimolar).
* CONSTANTS[51] is Ca_o in component extracellular_calcium_concentration (millimolar).
* STATES[11] is Ca_i in component intracellular_calcium_concentration (millimolar).
* CONSTANTS[52] is K_mk1 in component time_independent_potassium_current (millimolar).
* CONSTANTS[53] is g_K1 in component time_independent_potassium_current (microS).
* CONSTANTS[54] is g_Kr1 in component rapid_delayed_rectifier_potassium_current (microS).
* CONSTANTS[55] is g_Kr2 in component rapid_delayed_rectifier_potassium_current (microS).
* STATES[12] is xr1 in component rapid_delayed_rectifier_potassium_current_xr1_gate (dimensionless).
* STATES[13] is xr2 in component rapid_delayed_rectifier_potassium_current_xr2_gate (dimensionless).
* ALGEBRAIC[27] is alpha_xr1 in component rapid_delayed_rectifier_potassium_current_xr1_gate (per_second).
* ALGEBRAIC[28] is beta_xr1 in component rapid_delayed_rectifier_potassium_current_xr1_gate (per_second).
* ALGEBRAIC[29] is alpha_xr2 in component rapid_delayed_rectifier_potassium_current_xr2_gate (per_second).
* ALGEBRAIC[30] is beta_xr2 in component rapid_delayed_rectifier_potassium_current_xr2_gate (per_second).
* CONSTANTS[56] is g_Ks in component slow_delayed_rectifier_potassium_current (microS).
* STATES[14] is xs in component slow_delayed_rectifier_potassium_current_xs_gate (dimensionless).
* ALGEBRAIC[32] is alpha_xs in component slow_delayed_rectifier_potassium_current_xs_gate (per_second).
* ALGEBRAIC[33] is beta_xs in component slow_delayed_rectifier_potassium_current_xs_gate (per_second).
* ALGEBRAIC[34] is i_KNa in component sodium_activated_potassium_current (nanoA).
* CONSTANTS[57] is g_K_Na in component sodium_activated_potassium_current (microS).
* CONSTANTS[58] is K_kna in component sodium_activated_potassium_current (millimolar).
* CONSTANTS[59] is g_Na in component fast_sodium_current (microS).
* STATES[15] is m in component fast_sodium_current_m_gate (dimensionless).
* STATES[16] is h in component fast_sodium_current_h_gate (dimensionless).
* ALGEBRAIC[37] is alpha_m in component fast_sodium_current_m_gate (per_second).
* ALGEBRAIC[38] is beta_m in component fast_sodium_current_m_gate (per_second).
* CONSTANTS[60] is delta_m in component fast_sodium_current_m_gate (millivolt).
* ALGEBRAIC[36] is E0_m in component fast_sodium_current_m_gate (millivolt).
* ALGEBRAIC[39] is alpha_h in component fast_sodium_current_h_gate (per_second).
* ALGEBRAIC[40] is beta_h in component fast_sodium_current_h_gate (per_second).
* CONSTANTS[61] is g_pna in component persistent_sodium_current (microS).
* CONSTANTS[62] is g_bna in component sodium_background_current (microS).
* ALGEBRAIC[49] is i_Ca_L in component L_type_Ca_channel (nanoA).
* CONSTANTS[63] is P_Ca_L in component L_type_Ca_channel (nanoA_per_millimolar).
* CONSTANTS[64] is P_CaK in component L_type_Ca_channel (dimensionless).
* CONSTANTS[65] is P_CaNa in component L_type_Ca_channel (dimensionless).
* STATES[17] is Ca_ds in component intracellular_calcium_concentration (millimolar).
* STATES[18] is d in component L_type_Ca_channel_d_gate (dimensionless).
* STATES[19] is f in component L_type_Ca_channel_f_gate (dimensionless).
* STATES[20] is f2 in component L_type_Ca_channel_f2_gate (dimensionless).
* STATES[21] is f2ds in component L_type_Ca_channel_f2ds_gate (dimensionless).
* CONSTANTS[66] is Km_f2 in component L_type_Ca_channel (millimolar).
* CONSTANTS[67] is Km_f2ds in component L_type_Ca_channel (millimolar).
* CONSTANTS[68] is R_decay in component L_type_Ca_channel (per_second).
* CONSTANTS[69] is FrICa in component L_type_Ca_channel (dimensionless).
* ALGEBRAIC[51] is alpha_d in component L_type_Ca_channel_d_gate (per_second).
* ALGEBRAIC[52] is beta_d in component L_type_Ca_channel_d_gate (per_second).
* ALGEBRAIC[50] is E0_d in component L_type_Ca_channel_d_gate (millivolt).
* CONSTANTS[70] is speed_d in component L_type_Ca_channel_d_gate (dimensionless).
* ALGEBRAIC[54] is alpha_f in component L_type_Ca_channel_f_gate (per_second).
* ALGEBRAIC[55] is beta_f in component L_type_Ca_channel_f_gate (per_second).
* CONSTANTS[71] is speed_f in component L_type_Ca_channel_f_gate (dimensionless).
* CONSTANTS[72] is delta_f in component L_type_Ca_channel_f_gate (millivolt).
* ALGEBRAIC[53] is E0_f in component L_type_Ca_channel_f_gate (millivolt).
* CONSTANTS[73] is g_bca in component calcium_background_current (microS).
* CONSTANTS[74] is g_to in component transient_outward_current (microS).
* CONSTANTS[75] is g_tos in component transient_outward_current (dimensionless).
* STATES[22] is s in component transient_outward_current_s_gate (dimensionless).
* STATES[23] is r in component transient_outward_current_r_gate (dimensionless).
* ALGEBRAIC[58] is alpha_s in component transient_outward_current_s_gate (per_second).
* ALGEBRAIC[59] is beta_s in component transient_outward_current_s_gate (per_second).
* CONSTANTS[76] is i_NaK_max in component sodium_potassium_pump (nanoA).
* CONSTANTS[77] is K_mK in component sodium_potassium_pump (millimolar).
* CONSTANTS[78] is K_mNa in component sodium_potassium_pump (millimolar).
* ALGEBRAIC[63] is i_NaCa in component sodium_calcium_exchanger (nanoA).
* CONSTANTS[79] is k_NaCa in component sodium_calcium_exchanger (nanoA).
* CONSTANTS[80] is n_NaCa in component sodium_calcium_exchanger (dimensionless).
* CONSTANTS[81] is d_NaCa in component sodium_calcium_exchanger (dimensionless).
* CONSTANTS[82] is gamma in component sodium_calcium_exchanger (dimensionless).
* CONSTANTS[83] is FRiNaCa in component sodium_calcium_exchanger (dimensionless).
* ALGEBRAIC[65] is i_up in component sarcoplasmic_reticulum_calcium_pump (millimolar_per_second).
* CONSTANTS[128] is K_1 in component sarcoplasmic_reticulum_calcium_pump (dimensionless).
* ALGEBRAIC[64] is K_2 in component sarcoplasmic_reticulum_calcium_pump (millimolar).
* CONSTANTS[84] is K_cyca in component sarcoplasmic_reticulum_calcium_pump (millimolar).
* CONSTANTS[85] is K_xcs in component sarcoplasmic_reticulum_calcium_pump (dimensionless).
* CONSTANTS[86] is K_srca in component sarcoplasmic_reticulum_calcium_pump (millimolar).
* CONSTANTS[87] is alpha_up in component sarcoplasmic_reticulum_calcium_pump (millimolar_per_second).
* CONSTANTS[88] is beta_up in component sarcoplasmic_reticulum_calcium_pump (millimolar_per_second).
* STATES[24] is Ca_up in component intracellular_calcium_concentration (millimolar).
* CONSTANTS[89] is flag_ingib in component sarcoplasmic_reticulum_calcium_pump (dimensionless).
* CONSTANTS[90] is K_inh in component sarcoplasmic_reticulum_calcium_pump (millimolar).
* ALGEBRAIC[66] is i_trans in component calcium_translocation (millimolar_per_second).
* STATES[25] is Ca_rel in component intracellular_calcium_concentration (millimolar).
* CONSTANTS[91] is a_tr in component calcium_translocation (per_second).
* CONSTANTS[92] is alpha_CaS in component calcium_translocation (per_millimolar_second).
* CONSTANTS[93] is beta_CaS in component calcium_translocation (per_second).
* CONSTANTS[94] is CaS_tot in component calcium_translocation (millimolar).
* CONSTANTS[129] is beta in component calcium_translocation (millimolar).
* ALGEBRAIC[75] is i_rel in component calcium_release (millimolar_per_second).
* ALGEBRAIC[67] is VoltDep in component calcium_release (dimensionless).
* ALGEBRAIC[70] is RegBindSite in component calcium_release (dimensionless).
* ALGEBRAIC[68] is CaiReg in component calcium_release (dimensionless).
* ALGEBRAIC[69] is CadsReg in component calcium_release (dimensionless).
* ALGEBRAIC[71] is ActRate in component calcium_release (per_second).
* ALGEBRAIC[72] is InactRate in component calcium_release (per_second).
* CONSTANTS[95] is SRLeak in component calcium_release (per_second).
* CONSTANTS[96] is K_m_rel in component calcium_release (per_second).
* CONSTANTS[97] is K_m_Ca_cyt in component calcium_release (millimolar).
* CONSTANTS[98] is K_m_Ca_ds in component calcium_release (millimolar).
* ALGEBRAIC[74] is PrecFrac in component calcium_release (dimensionless).
* STATES[26] is ActFrac in component calcium_release (dimensionless).
* STATES[27] is ProdFrac in component calcium_release (dimensionless).
* ALGEBRAIC[73] is SpeedRel in component calcium_release (dimensionless).
* CONSTANTS[131] is V_i in component intracellular_calcium_concentration (micrometre3).
* CONSTANTS[99] is n_NaK in component intracellular_sodium_concentration (dimensionless).
* CONSTANTS[100] is K_b in component extracellular_potassium_concentration (millimolar).
* CONSTANTS[132] is V_e in component intracellular_calcium_concentration (micrometre3).
* CONSTANTS[101] is radius in component intracellular_calcium_concentration (micrometre).
* CONSTANTS[102] is length in component intracellular_calcium_concentration (micrometre).
* CONSTANTS[127] is V_Cell in component intracellular_calcium_concentration (micrometre3).
* CONSTANTS[103] is V_i_ratio in component intracellular_calcium_concentration (dimensionless).
* CONSTANTS[104] is V_ds_ratio in component intracellular_calcium_concentration (dimensionless).
* CONSTANTS[105] is V_rel_ratio in component intracellular_calcium_concentration (dimensionless).
* CONSTANTS[106] is V_e_ratio in component intracellular_calcium_concentration (dimensionless).
* CONSTANTS[107] is V_up_ratio in component intracellular_calcium_concentration (dimensionless).
* CONSTANTS[108] is Kdecay in component intracellular_calcium_concentration (per_second).
* ALGEBRAIC[76] is N_A in component intracellular_calcium_concentration (dimensionless).
* ALGEBRAIC[77] is pi_N_A in component intracellular_calcium_concentration (dimensionless).
* CONSTANTS[109] is pi_min in component intracellular_calcium_concentration (dimensionless).
* CONSTANTS[110] is a_on in component intracellular_calcium_concentration (per_millimolar_second).
* CONSTANTS[111] is a_off in component intracellular_calcium_concentration (per_second).
* STATES[28] is B_1 in component intracellular_calcium_concentration (millimolar).
* CONSTANTS[112] is B_1_tot in component intracellular_calcium_concentration (millimolar).
* CONSTANTS[113] is b_1_on in component intracellular_calcium_concentration (per_millimolar_second).
* CONSTANTS[114] is b_1_off in component intracellular_calcium_concentration (per_second).
* STATES[29] is B_2 in component intracellular_calcium_concentration (millimolar).
* CONSTANTS[115] is B_2_tot in component intracellular_calcium_concentration (millimolar).
* CONSTANTS[116] is b_2_on in component intracellular_calcium_concentration (per_millimolar_second).
* CONSTANTS[117] is b_2_off in component intracellular_calcium_concentration (per_second).
* CONSTANTS[118] is g_fibro_junct in component fibroblast (microS).
* CONSTANTS[119] is g_fibro in component fibroblast (microS).
* CONSTANTS[120] is c_fibro in component fibroblast (microF).
* CONSTANTS[121] is g_fibro_stretch in component fibroblast (microS).
* CONSTANTS[122] is E_fibro_stretch in component fibroblast (millivolt).
* STATES[30] is V_fibro in component fibroblast (millivolt).
* ALGEBRAIC[78] is i_fibro in component fibroblast (nanoA).
* ALGEBRAIC[79] is i_fibro_junct in component fibroblast (nanoA).
* RATES[1] is d/dt N in component crossbridge_kinetics (dimensionless).
* RATES[3] is d/dt l_1 in component length (micrometre).
* RATES[4] is d/dt l_2 in component length (micrometre).
* RATES[5] is d/dt l_3 in component length (micrometre).
* RATES[0] is d/dt v in component CE_velocity (micrometre_per_second).
* RATES[2] is d/dt w in component PE_velocity (micrometre_per_second).
* RATES[7] is d/dt V in component membrane (millivolt).
* RATES[12] is d/dt xr1 in component rapid_delayed_rectifier_potassium_current_xr1_gate (dimensionless).
* RATES[13] is d/dt xr2 in component rapid_delayed_rectifier_potassium_current_xr2_gate (dimensionless).
* RATES[14] is d/dt xs in component slow_delayed_rectifier_potassium_current_xs_gate (dimensionless).
* RATES[15] is d/dt m in component fast_sodium_current_m_gate (dimensionless).
* RATES[16] is d/dt h in component fast_sodium_current_h_gate (dimensionless).
* RATES[18] is d/dt d in component L_type_Ca_channel_d_gate (dimensionless).
* RATES[19] is d/dt f in component L_type_Ca_channel_f_gate (dimensionless).
* RATES[20] is d/dt f2 in component L_type_Ca_channel_f2_gate (dimensionless).
* RATES[21] is d/dt f2ds in component L_type_Ca_channel_f2ds_gate (dimensionless).
* RATES[22] is d/dt s in component transient_outward_current_s_gate (dimensionless).
* RATES[23] is d/dt r in component transient_outward_current_r_gate (dimensionless).
* RATES[26] is d/dt ActFrac in component calcium_release (dimensionless).
* RATES[27] is d/dt ProdFrac in component calcium_release (dimensionless).
* RATES[10] is d/dt Na_i in component intracellular_sodium_concentration (millimolar).
* RATES[8] is d/dt K_o in component extracellular_potassium_concentration (millimolar).
* RATES[9] is d/dt K_i in component intracellular_potassium_concentration (millimolar).
* RATES[6] is d/dt A in component intracellular_calcium_concentration (millimolar).
* RATES[28] is d/dt B_1 in component intracellular_calcium_concentration (millimolar).
* RATES[29] is d/dt B_2 in component intracellular_calcium_concentration (millimolar).
* RATES[11] is d/dt Ca_i in component intracellular_calcium_concentration (millimolar).
* RATES[17] is d/dt Ca_ds in component intracellular_calcium_concentration (millimolar).
* RATES[24] is d/dt Ca_up in component intracellular_calcium_concentration (millimolar).
* RATES[25] is d/dt Ca_rel in component intracellular_calcium_concentration (millimolar).
* RATES[30] is d/dt V_fibro in component fibroblast (millivolt).
* There are a total of 35 condition variables.
*/
void
initConsts(double* CONSTANTS, double* RATES, double *STATES)
{
CONSTANTS[0] = 0;
CONSTANTS[1] = 14.6;
CONSTANTS[2] = 0.84;
CONSTANTS[3] = 14.6;
CONSTANTS[4] = 0.0018;
CONSTANTS[5] = 48;
CONSTANTS[6] = 0.015;
CONSTANTS[7] = 30;
CONSTANTS[8] = 3;
CONSTANTS[9] = 0.6;
CONSTANTS[10] = 0.705;
CONSTANTS[11] = 3;
CONSTANTS[12] = 0.9;
CONSTANTS[13] = 5.5;
CONSTANTS[14] = 0.25;
CONSTANTS[15] = 0.5;
CONSTANTS[16] = 4;
CONSTANTS[17] = 2;
CONSTANTS[18] = 0.525139356105856;
CONSTANTS[19] = 1;
CONSTANTS[20] = 1.14;
CONSTANTS[21] = 17.3;
CONSTANTS[22] = 259;
CONSTANTS[23] = 17.3;
CONSTANTS[24] = 15;
CONSTANTS[25] = 0.964285;
CONSTANTS[26] = 1;
CONSTANTS[27] = 40;
STATES[0] = 0;
CONSTANTS[28] = 10;
CONSTANTS[29] = 5;
STATES[1] = 7.455e-8;
STATES[2] = 0;
STATES[3] = 0.436333342969918;
STATES[4] = 0.436333525334166;
STATES[5] = 0.088805830771694;
STATES[6] = 0.00015;
CONSTANTS[30] = 0.07;
CONSTANTS[31] = 0.6;
CONSTANTS[32] = 0.52;
CONSTANTS[33] = 0.06;
CONSTANTS[34] = 10000;
CONSTANTS[35] = 0.0025;
CONSTANTS[36] = -3;
CONSTANTS[37] = 16;
CONSTANTS[38] = 0.0015;
CONSTANTS[39] = 16;
CONSTANTS[40] = 0.0015;
CONSTANTS[41] = 46;
CONSTANTS[42] = 0;
CONSTANTS[43] = 39;
CONSTANTS[44] = 0;
STATES[7] = -93.658148;
CONSTANTS[45] = 8314.472;
CONSTANTS[46] = 310;
CONSTANTS[47] = 96485.3415;
CONSTANTS[48] = 9.5e-5;
CONSTANTS[49] = 0.03;
STATES[8] = 3.988;
CONSTANTS[50] = 140;
STATES[9] = 139.054;
STATES[10] = 5.18787513289509;
CONSTANTS[51] = 2;
STATES[11] = 6.15e-6;
CONSTANTS[52] = 10;
CONSTANTS[53] = 0.5;
CONSTANTS[54] = 0.0021;
CONSTANTS[55] = 0.0013;
STATES[12] = 8.88859784542779e-6;
STATES[13] = 1.53745791069154e-7;
CONSTANTS[56] = 0.0026;
STATES[14] = 0.001;
CONSTANTS[57] = 0;
CONSTANTS[58] = 20;
CONSTANTS[59] = 2.5;
STATES[15] = 0.0015;
STATES[16] = 0.995;
CONSTANTS[60] = 1e-5;
CONSTANTS[61] = 0.004;
CONSTANTS[62] = 0.0006;
CONSTANTS[63] = 0.1;
CONSTANTS[64] = 0.002;
CONSTANTS[65] = 0.01;
STATES[17] = 2.55e-6;
STATES[18] = 0;
STATES[19] = 1;
STATES[20] = 1;
STATES[21] = 0.997;
CONSTANTS[66] = 100000;
CONSTANTS[67] = 0.001;
CONSTANTS[68] = 20;
CONSTANTS[69] = 1;
CONSTANTS[70] = 3;
CONSTANTS[71] = 0.3;
CONSTANTS[72] = 0.0001;
CONSTANTS[73] = 0.00025;
CONSTANTS[74] = 0.006;
CONSTANTS[75] = 0;
STATES[22] = 0.997044616031121;
STATES[23] = 1.63117173173398e-8;
CONSTANTS[76] = 0.7;
CONSTANTS[77] = 1;
CONSTANTS[78] = 24.2;
CONSTANTS[79] = 0.0005;
CONSTANTS[80] = 3;
CONSTANTS[81] = 0;
CONSTANTS[82] = 0.5;
CONSTANTS[83] = 0.001;
CONSTANTS[84] = 0.00015;
CONSTANTS[85] = 0.4;
CONSTANTS[86] = 0.5;
CONSTANTS[87] = 1;
CONSTANTS[88] = 0.03;
STATES[24] = 0.994579;
CONSTANTS[89] = 0;
CONSTANTS[90] = 4;
STATES[25] = 0.989665;
CONSTANTS[91] = 15;
CONSTANTS[92] = 50000;
CONSTANTS[93] = 32500;
CONSTANTS[94] = 40;
CONSTANTS[95] = 0.05;
CONSTANTS[96] = 10000;
CONSTANTS[97] = 0.0005;
CONSTANTS[98] = 0.01;
STATES[26] = 0.001914;
STATES[27] = 0.2854569;
CONSTANTS[99] = 1.5;
CONSTANTS[100] = 4;
CONSTANTS[101] = 12;
CONSTANTS[102] = 74;
CONSTANTS[103] = 0.49;
CONSTANTS[104] = 0.1;
CONSTANTS[105] = 0.003;
CONSTANTS[106] = 0.4;
CONSTANTS[107] = 0.03;
CONSTANTS[108] = 10;
CONSTANTS[109] = 0.03;
CONSTANTS[110] = 70000;
CONSTANTS[111] = 200;
STATES[28] = 0;
CONSTANTS[112] = 0.08;
CONSTANTS[113] = 100000;
CONSTANTS[114] = 182;
STATES[29] = 0;
CONSTANTS[115] = 0.1;
CONSTANTS[116] = 1000;
CONSTANTS[117] = 3;
CONSTANTS[118] = 2.9e-4;
CONSTANTS[119] = 2e-4;
CONSTANTS[120] = 1e-5;
CONSTANTS[121] = 0;
CONSTANTS[122] = 0;
STATES[30] = -20;
CONSTANTS[123] = CONSTANTS[25]*CONSTANTS[13];
CONSTANTS[124] = CONSTANTS[13]/10.0000;
CONSTANTS[125] = ( CONSTANTS[14]*(0.400000+ 0.400000*CONSTANTS[14]))/( CONSTANTS[13]*pow( (CONSTANTS[14]+1.00000)*0.400000, 2.00000));
CONSTANTS[126] = ( 0.400000*CONSTANTS[14]+1.00000)/( CONSTANTS[14]*CONSTANTS[13]);
CONSTANTS[127] = ( 3.14159*pow(CONSTANTS[101]/1000.00, 2.00000)*CONSTANTS[102])/1000.00;
CONSTANTS[128] = ( CONSTANTS[84]*CONSTANTS[85])/CONSTANTS[86];
CONSTANTS[129] = CONSTANTS[93]/CONSTANTS[92];
CONSTANTS[130] = ( CONSTANTS[14]*CONSTANTS[15]*pow(CONSTANTS[124]/CONSTANTS[13], 2.00000))/( 3.00000*CONSTANTS[14]*CONSTANTS[15] - ( (CONSTANTS[14]+1.00000)*CONSTANTS[124])/CONSTANTS[13]);
CONSTANTS[131] = CONSTANTS[127]*CONSTANTS[103];
CONSTANTS[132] = CONSTANTS[127]*CONSTANTS[106];
RATES[1] = 0.1001;
RATES[3] = 0.1001;
RATES[4] = 0.1001;
RATES[5] = 0.1001;
RATES[0] = 0.1001;
RATES[2] = 0.1001;
RATES[7] = 0.1001;
RATES[12] = 0.1001;
RATES[13] = 0.1001;
RATES[14] = 0.1001;
RATES[15] = 0.1001;
RATES[16] = 0.1001;
RATES[18] = 0.1001;
RATES[19] = 0.1001;
RATES[20] = 0.1001;
RATES[21] = 0.1001;
RATES[22] = 0.1001;
RATES[23] = 0.1001;
RATES[26] = 0.1001;
RATES[27] = 0.1001;
RATES[10] = 0.1001;
RATES[8] = 0.1001;
RATES[9] = 0.1001;
RATES[6] = 0.1001;
RATES[28] = 0.1001;
RATES[29] = 0.1001;
RATES[11] = 0.1001;
RATES[17] = 0.1001;
RATES[24] = 0.1001;
RATES[25] = 0.1001;
RATES[30] = 0.1001;
}
void
computeResiduals(double VOI, double* CONSTANTS, double* RATES, double* OLDRATES, double* STATES,
double* OLDSTATES, double* ALGEBRAIC, double* CONDVARS)
{
resid[0] = RATES[1] - ALGEBRAIC[84];
resid[1] = RATES[3] - ALGEBRAIC[8];
resid[2] = RATES[4] - ALGEBRAIC[88];
resid[3] = RATES[5] - (CONDVAR[8]>=0.00000&&CONDVAR[9]<=0.00000&&CONDVAR[10]<=0.00000 ? - ((STATES[4]+STATES[5]) - CONSTANTS[18])/CONSTANTS[35] : ALGEBRAIC[89]);
resid[4] = RATES[0] - (ALGEBRAIC[12]==0.00000 ? ( CONSTANTS[1]*CONSTANTS[2]*exp( CONSTANTS[1]*(STATES[4] - STATES[3]))*(ALGEBRAIC[87] - STATES[0]) - ( CONSTANTS[7]*ALGEBRAIC[84]*ALGEBRAIC[17]+ ALGEBRAIC[9]*ALGEBRAIC[10]*pow(STATES[0], 2.00000)))/( CONSTANTS[7]*STATES[1]*ALGEBRAIC[18]+ALGEBRAIC[10]) : ALGEBRAIC[86]);
resid[5] = RATES[2] - (ALGEBRAIC[85]==1.00000&&ALGEBRAIC[12] != 0.00000 ? (( ALGEBRAIC[12]*(ALGEBRAIC[86] - ALGEBRAIC[11]*pow(STATES[2] - STATES[0], 2.00000)) - CONSTANTS[1]*CONSTANTS[2]*exp( CONSTANTS[1]*(STATES[4] - STATES[3]))*(STATES[2] - STATES[0])) - CONSTANTS[3]*CONSTANTS[4]*exp( CONSTANTS[3]*STATES[4])*STATES[2])/ALGEBRAIC[12] : ALGEBRAIC[85]==0.00000&&ALGEBRAIC[12] != 0.00000 ? (ALGEBRAIC[86] - ALGEBRAIC[11]*pow(STATES[2] - STATES[0], 2.00000)) - ( CONSTANTS[1]*CONSTANTS[2]*exp( CONSTANTS[1]*(STATES[4] - STATES[3]))*(STATES[2] - STATES[0])+ ( CONSTANTS[3]*CONSTANTS[4]*exp( CONSTANTS[3]*STATES[4])+ CONSTANTS[5]*CONSTANTS[6]*exp( CONSTANTS[5]*STATES[5]))*STATES[2])/ALGEBRAIC[12] : ALGEBRAIC[12]==0.00000 ? 0.00000 : 0.0/0.0);
resid[6] = RATES[7] - (- 1.00000/CONSTANTS[48])*(ALGEBRAIC[19]+ALGEBRAIC[25]+ALGEBRAIC[57]+ALGEBRAIC[26]+ALGEBRAIC[31]+ALGEBRAIC[60]+ALGEBRAIC[35]+ALGEBRAIC[42]+ALGEBRAIC[41]+ALGEBRAIC[45]+ALGEBRAIC[48]+ALGEBRAIC[61]+ALGEBRAIC[62]+ALGEBRAIC[43]+ALGEBRAIC[46]+ALGEBRAIC[44]+ALGEBRAIC[47]+ALGEBRAIC[56]);
resid[7] = RATES[12] - ALGEBRAIC[27]*(1.00000 - STATES[12]) - ALGEBRAIC[28]*STATES[12];
resid[8] = RATES[13] - ALGEBRAIC[29]*(1.00000 - STATES[13]) - ALGEBRAIC[30]*STATES[13];
resid[9] = RATES[14] - ALGEBRAIC[32]*(1.00000 - STATES[14]) - ALGEBRAIC[33]*STATES[14];
resid[10] = RATES[15] - ALGEBRAIC[37]*(1.00000 - STATES[15]) - ALGEBRAIC[38]*STATES[15];
resid[11] = RATES[16] - ALGEBRAIC[39]*(1.00000 - STATES[16]) - ALGEBRAIC[40]*STATES[16];
resid[12] = RATES[18] - CONSTANTS[70]*( ALGEBRAIC[51]*(1.00000 - STATES[18]) - ALGEBRAIC[52]*STATES[18]);
resid[13] = RATES[19] - CONSTANTS[71]*( ALGEBRAIC[54]*(1.00000 - STATES[19]) - ALGEBRAIC[55]*STATES[19]);
resid[14] = RATES[20] - 1.00000 - 1.00000*(STATES[11]/(CONSTANTS[66]+STATES[11])+STATES[20]);
resid[15] = RATES[21] - CONSTANTS[68]*(1.00000 - (STATES[17]/(CONSTANTS[67]+STATES[17])+STATES[21]));
resid[16] = RATES[22] - ALGEBRAIC[58]*(1.00000 - STATES[22]) - ALGEBRAIC[59]*STATES[22];
resid[17] = RATES[23] - 333.000*(1.00000/(1.00000+exp(- (STATES[7]+4.00000)/5.00000)) - STATES[23]);
resid[18] = RATES[26] - ALGEBRAIC[74]*ALGEBRAIC[73]*ALGEBRAIC[71] - STATES[26]*ALGEBRAIC[73]*ALGEBRAIC[72];
resid[19] = RATES[27] - STATES[26]*ALGEBRAIC[73]*ALGEBRAIC[72] - ALGEBRAIC[73]*0.600000*STATES[27];
resid[20] = RATES[10] - (- 1.00000/( 1.00000*CONSTANTS[131]*CONSTANTS[47]))*(ALGEBRAIC[35]+ALGEBRAIC[41]+ALGEBRAIC[42]+ALGEBRAIC[45]+ALGEBRAIC[48]+ (CONSTANTS[99]/(CONSTANTS[99] - 1.00000))*ALGEBRAIC[60]+ (CONSTANTS[80]/(CONSTANTS[80] - 2.00000))*ALGEBRAIC[63]);
resid[21] = RATES[8] - ( 1.00000*(((ALGEBRAIC[26]+ALGEBRAIC[31]+ALGEBRAIC[25]+ALGEBRAIC[57]) - (1.00000/(CONSTANTS[99] - 1.00000))*ALGEBRAIC[60])+ALGEBRAIC[44]+ALGEBRAIC[47]))/( 1.00000*CONSTANTS[132]*CONSTANTS[47]) - 0.700000*(STATES[8] - CONSTANTS[100]);
resid[22] = RATES[9] - (- 1.00000/( 1.00000*CONSTANTS[131]*CONSTANTS[47]))*((ALGEBRAIC[25]+ALGEBRAIC[26]+ALGEBRAIC[31]+ALGEBRAIC[44]+ALGEBRAIC[47]+ALGEBRAIC[57]) - (1.00000/(CONSTANTS[99] - 1.00000))*ALGEBRAIC[60]);
resid[23] = RATES[6] - CONSTANTS[110]*(CONSTANTS[30] - STATES[6])*STATES[11] - CONSTANTS[111]*exp( - CONSTANTS[27]*STATES[6])*ALGEBRAIC[77]*STATES[6];
resid[24] = RATES[28] - CONSTANTS[113]*(CONSTANTS[112] - STATES[28])*STATES[11] - CONSTANTS[114]*STATES[28];
resid[25] = RATES[29] - CONSTANTS[116]*(CONSTANTS[115] - STATES[29])*STATES[11] - CONSTANTS[117]*STATES[29];
resid[26] = RATES[11] - (((( (- 1.00000/( 2.00000*1.00000*CONSTANTS[131]*CONSTANTS[47]))*((ALGEBRAIC[43]+ALGEBRAIC[56]) - (2.00000/(CONSTANTS[80] - 2.00000))*ALGEBRAIC[61])+ STATES[17]*CONSTANTS[104]*CONSTANTS[108]+( ALGEBRAIC[75]*CONSTANTS[105])/CONSTANTS[103]) - RATES[6]) - RATES[28]) - RATES[29]) - ALGEBRAIC[65];
resid[27] = RATES[17] - ( - 1.00000*ALGEBRAIC[46]+( 2.00000*ALGEBRAIC[62])/(CONSTANTS[80] - 2.00000))/( 2.00000*1.00000*CONSTANTS[104]*CONSTANTS[131]*CONSTANTS[47]) - STATES[17]*CONSTANTS[108];
resid[28] = RATES[24] - (CONSTANTS[103]/CONSTANTS[107])*ALGEBRAIC[65] - ALGEBRAIC[66];
resid[29] = RATES[25] - ( (CONSTANTS[107]/CONSTANTS[105])*ALGEBRAIC[66] - ALGEBRAIC[75])/(1.00000+( CONSTANTS[129]*CONSTANTS[94])/pow(STATES[25]+CONSTANTS[129], 2.00000));
resid[30] = RATES[30] - - (ALGEBRAIC[78]+ALGEBRAIC[79])/CONSTANTS[120];
}
void
computeVariables(double VOI, double* CONSTANTS, double* RATES, double* STATES, double* ALGEBRAIC)
{
ALGEBRAIC[1] = CONSTANTS[2]*(exp( CONSTANTS[1]*(STATES[4] - STATES[3])) - 1.00000);
ALGEBRAIC[2] = CONSTANTS[4]*(exp( CONSTANTS[3]*STATES[4]) - 1.00000);
ALGEBRAIC[34] = (( CONSTANTS[57]*STATES[10])/(STATES[10]+CONSTANTS[58]))*(STATES[7] - ALGEBRAIC[21]);
ALGEBRAIC[49] = ALGEBRAIC[43]+ALGEBRAIC[44]+ALGEBRAIC[45]+ALGEBRAIC[46]+ALGEBRAIC[47]+ALGEBRAIC[48];
ALGEBRAIC[67] = exp( 0.0800000*(STATES[7] - 40.0000));
ALGEBRAIC[80] = CONSTANTS[7]*ALGEBRAIC[17]*STATES[1];
}
void
computeEssentialVariables(double VOI, double* CONSTANTS, double* RATES, double* STATES, double* ALGEBRAIC)
{
ALGEBRAIC[8] = STATES[0];
ALGEBRAIC[9] = (CONDVAR[11]<=0.00000 ? CONSTANTS[37] : CONSTANTS[39]);
ALGEBRAIC[10] = (CONDVAR[12]<=0.00000 ? CONSTANTS[38]*exp( CONSTANTS[37]*STATES[3]) : CONSTANTS[40]*exp( CONSTANTS[39]*STATES[3]));
ALGEBRAIC[11] = (CONDVAR[13]<=0.00000 ? CONSTANTS[41] : CONSTANTS[43]);
ALGEBRAIC[12] = (CONDVAR[14]<=0.00000 ? CONSTANTS[42]*exp( CONSTANTS[41]*(STATES[4] - STATES[3])) : CONSTANTS[44]*exp( CONSTANTS[43]*(STATES[4] - STATES[3])));
ALGEBRAIC[13] = (CONDVAR[15]<=0.00000 ? ( CONSTANTS[14]*(1.00000+STATES[0]/CONSTANTS[13]))/(CONSTANTS[14] - STATES[0]/CONSTANTS[13]) : (1.00000+CONSTANTS[15]) - ( pow(CONSTANTS[15], 2.00000)*CONSTANTS[14])/( (( CONSTANTS[14]*CONSTANTS[15])/CONSTANTS[130])*pow(STATES[0]/CONSTANTS[13], 2.00000)+( (CONSTANTS[14]+1.00000)*STATES[0])/CONSTANTS[13]+ CONSTANTS[14]*CONSTANTS[15]));
ALGEBRAIC[14] = (CONDVAR[16]<=0.00000&&CONDVAR[17]<=0.00000 ? 1.00000+( 0.600000*STATES[0])/CONSTANTS[13] : CONDVAR[18]<0.00000&&CONDVAR[19]<=0.00000 ? ALGEBRAIC[13]/(( ( 0.400000*CONSTANTS[14]+1.00000)*STATES[0])/( CONSTANTS[14]*CONSTANTS[13])+1.00000) : ( ALGEBRAIC[13]*exp( - CONSTANTS[26]*pow((STATES[0] - CONSTANTS[124])/CONSTANTS[13], CONSTANTS[16])))/(( ( 0.400000*CONSTANTS[14]+1.00000)*STATES[0])/( CONSTANTS[14]*CONSTANTS[13])+1.00000));
ALGEBRAIC[17] = ALGEBRAIC[13]/ALGEBRAIC[14];
ALGEBRAIC[15] = ( CONSTANTS[14]*1.00000*(1.00000+ 0.400000*CONSTANTS[14]+( 1.20000*STATES[0])/CONSTANTS[13]+ 0.600000*pow(STATES[0]/CONSTANTS[13], 2.00000)))/( CONSTANTS[13]*pow( (CONSTANTS[14] - STATES[0]/CONSTANTS[13])*(1.00000+( 0.600000*STATES[0])/CONSTANTS[13]), 2.00000));
ALGEBRAIC[16] = (1.00000/CONSTANTS[13])*exp( - CONSTANTS[26]*pow(STATES[0]/CONSTANTS[13] - CONSTANTS[124]/CONSTANTS[13], CONSTANTS[16]))*(( 0.400000*CONSTANTS[14]+1.00000)/CONSTANTS[14]+ CONSTANTS[26]*CONSTANTS[16]*(1.00000+( ( 0.400000*CONSTANTS[14]+1.00000)*STATES[0])/( CONSTANTS[14]*CONSTANTS[13]))*pow(STATES[0]/CONSTANTS[13] - CONSTANTS[124]/CONSTANTS[13], CONSTANTS[16] - 1.00000));
ALGEBRAIC[18] = (CONDVAR[20]<=0.00000 ? CONSTANTS[125] : CONDVAR[21]<0.00000&&CONDVAR[22]<=0.00000 ? ALGEBRAIC[15] : CONDVAR[23]<0.00000&&CONDVAR[24]<=0.00000 ? CONSTANTS[126] : ALGEBRAIC[16]);
ALGEBRAIC[19] = (CONDVAR[25]>=0.00000&&CONDVAR[26]<=0.00000&&CONDVAR[27]<=0.00000 ? CONSTANTS[36] : 0.00000);
ALGEBRAIC[21] = (( CONSTANTS[45]*CONSTANTS[46])/CONSTANTS[47])*log(STATES[8]/STATES[9]);
ALGEBRAIC[25] = ( (( CONSTANTS[53]*STATES[8])/(STATES[8]+CONSTANTS[52]))*(STATES[7] - ALGEBRAIC[21]))/(1.00000+exp(( ((STATES[7] - ALGEBRAIC[21]) - 10.0000)*CONSTANTS[47]*1.25000)/( CONSTANTS[45]*CONSTANTS[46])));
ALGEBRAIC[26] = (( ( CONSTANTS[54]*STATES[12]+ CONSTANTS[55]*STATES[13])*1.00000)/(1.00000+exp((STATES[7]+9.00000)/22.4000)))*(STATES[7] - ALGEBRAIC[21]);
ALGEBRAIC[27] = 50.0000/(1.00000+exp(- (STATES[7] - 5.00000)/9.00000));
ALGEBRAIC[28] = 0.0500000*exp(- (STATES[7] - 20.0000)/15.0000);
ALGEBRAIC[29] = 50.0000/(1.00000+exp(- (STATES[7] - 5.00000)/9.00000));
ALGEBRAIC[30] = 0.400000*exp(- pow((STATES[7]+30.0000)/30.0000, 3.00000));
ALGEBRAIC[22] = (( CONSTANTS[45]*CONSTANTS[46])/CONSTANTS[47])*log((STATES[8]+ CONSTANTS[49]*CONSTANTS[50])/(STATES[9]+ CONSTANTS[49]*STATES[10]));
ALGEBRAIC[31] = CONSTANTS[56]*pow(STATES[14], 2.00000)*(STATES[7] - ALGEBRAIC[22]);
ALGEBRAIC[32] = 14.0000/(1.00000+exp(- (STATES[7] - 40.0000)/9.00000));
ALGEBRAIC[33] = 1.00000*exp(- STATES[7]/45.0000);
ALGEBRAIC[24] = (( CONSTANTS[45]*CONSTANTS[46])/CONSTANTS[47])*log((CONSTANTS[50]+ 0.120000*STATES[8])/(STATES[10]+ 0.120000*STATES[9]));
ALGEBRAIC[35] = CONSTANTS[59]*pow(STATES[15], 3.00000)*STATES[16]*(STATES[7] - ALGEBRAIC[24]);
ALGEBRAIC[36] = STATES[7]+41.0000;
ALGEBRAIC[37] = (CONDVAR[28]<0.00000 ? 2000.00 : ( 200.000*ALGEBRAIC[36])/(1.00000 - exp( - 0.100000*ALGEBRAIC[36])));
ALGEBRAIC[38] = 8000.00*exp( - 0.0560000*(STATES[7]+66.0000));
ALGEBRAIC[39] = 20.0000*exp( - 0.125000*(STATES[7]+75.0000));
ALGEBRAIC[40] = 2000.00/(1.00000+ 320.000*exp( - 0.100000*(STATES[7]+75.0000)));
ALGEBRAIC[20] = (( CONSTANTS[45]*CONSTANTS[46])/CONSTANTS[47])*log(CONSTANTS[50]/STATES[10]);
ALGEBRAIC[41] = (( CONSTANTS[61]*1.00000)/(1.00000+exp(- (STATES[7]+52.0000)/8.00000)))*(STATES[7] - ALGEBRAIC[20]);
ALGEBRAIC[42] = CONSTANTS[62]*(STATES[7] - ALGEBRAIC[20]);
ALGEBRAIC[43] = ((( (1.00000 - CONSTANTS[69])*4.00000*CONSTANTS[63]*STATES[18]*STATES[19]*STATES[20]*(STATES[7] - 50.0000)*CONSTANTS[47])/( CONSTANTS[45]*CONSTANTS[46]))/(1.00000 - exp(( - (STATES[7] - 50.0000)*CONSTANTS[47]*2.00000)/( CONSTANTS[45]*CONSTANTS[46]))))*( STATES[11]*exp(( 100.000*CONSTANTS[47])/( CONSTANTS[45]*CONSTANTS[46])) - CONSTANTS[51]*exp(( - (STATES[7] - 50.0000)*CONSTANTS[47]*2.00000)/( CONSTANTS[45]*CONSTANTS[46])));
ALGEBRAIC[44] = ((( (1.00000 - CONSTANTS[69])*CONSTANTS[64]*CONSTANTS[63]*STATES[18]*STATES[19]*STATES[20]*(STATES[7] - 50.0000)*CONSTANTS[47])/( CONSTANTS[45]*CONSTANTS[46]))/(1.00000 - exp(( - (STATES[7] - 50.0000)*CONSTANTS[47])/( CONSTANTS[45]*CONSTANTS[46]))))*( STATES[9]*exp(( 50.0000*CONSTANTS[47])/( CONSTANTS[45]*CONSTANTS[46])) - STATES[8]*exp(( - (STATES[7] - 50.0000)*CONSTANTS[47])/( CONSTANTS[45]*CONSTANTS[46])));
ALGEBRAIC[45] = ((( (1.00000 - CONSTANTS[69])*CONSTANTS[65]*CONSTANTS[63]*STATES[18]*STATES[19]*STATES[20]*(STATES[7] - 50.0000)*CONSTANTS[47])/( CONSTANTS[45]*CONSTANTS[46]))/(1.00000 - exp(( - (STATES[7] - 50.0000)*CONSTANTS[47])/( CONSTANTS[45]*CONSTANTS[46]))))*( STATES[10]*exp(( 50.0000*CONSTANTS[47])/( CONSTANTS[45]*CONSTANTS[46])) - CONSTANTS[50]*exp(( - (STATES[7] - 50.0000)*CONSTANTS[47])/( CONSTANTS[45]*CONSTANTS[46])));
ALGEBRAIC[46] = ((( CONSTANTS[69]*4.00000*CONSTANTS[63]*STATES[18]*STATES[19]*STATES[21]*(STATES[7] - 50.0000)*CONSTANTS[47])/( CONSTANTS[45]*CONSTANTS[46]))/(1.00000 - exp(( - (STATES[7] - 50.0000)*CONSTANTS[47]*2.00000)/( CONSTANTS[45]*CONSTANTS[46]))))*( STATES[11]*exp(( 100.000*CONSTANTS[47])/( CONSTANTS[45]*CONSTANTS[46])) - CONSTANTS[51]*exp(( - (STATES[7] - 50.0000)*CONSTANTS[47]*2.00000)/( CONSTANTS[45]*CONSTANTS[46])));
ALGEBRAIC[47] = ((( CONSTANTS[69]*CONSTANTS[64]*CONSTANTS[63]*STATES[18]*STATES[19]*STATES[21]*(STATES[7] - 50.0000)*CONSTANTS[47])/( CONSTANTS[45]*CONSTANTS[46]))/(1.00000 - exp(( - (STATES[7] - 50.0000)*CONSTANTS[47])/( CONSTANTS[45]*CONSTANTS[46]))))*( STATES[9]*exp(( 50.0000*CONSTANTS[47])/( CONSTANTS[45]*CONSTANTS[46])) - STATES[8]*exp(( - (STATES[7] - 50.0000)*CONSTANTS[47])/( CONSTANTS[45]*CONSTANTS[46])));
ALGEBRAIC[48] = ((( CONSTANTS[69]*CONSTANTS[65]*CONSTANTS[63]*STATES[18]*STATES[19]*STATES[21]*(STATES[7] - 50.0000)*CONSTANTS[47])/( CONSTANTS[45]*CONSTANTS[46]))/(1.00000 - exp(( - (STATES[7] - 50.0000)*CONSTANTS[47])/( CONSTANTS[45]*CONSTANTS[46]))))*( STATES[10]*exp(( 50.0000*CONSTANTS[47])/( CONSTANTS[45]*CONSTANTS[46])) - CONSTANTS[50]*exp(( - (STATES[7] - 50.0000)*CONSTANTS[47])/( CONSTANTS[45]*CONSTANTS[46])));
ALGEBRAIC[50] = (STATES[7]+24.0000) - 5.00000;
ALGEBRAIC[51] = (CONDVAR[29]<0.00000 ? 120.000 : ( 30.0000*ALGEBRAIC[50])/(1.00000 - exp(- ALGEBRAIC[50]/4.00000)));
ALGEBRAIC[52] = (CONDVAR[30]<0.00000 ? 120.000 : ( 12.0000*ALGEBRAIC[50])/(exp(ALGEBRAIC[50]/10.0000) - 1.00000));
ALGEBRAIC[53] = STATES[7]+34.0000;
ALGEBRAIC[54] = (CONDVAR[31]<0.00000 ? 25.0000 : ( 6.25000*ALGEBRAIC[53])/(exp(ALGEBRAIC[53]/4.00000) - 1.00000));
ALGEBRAIC[55] = 12.0000/(1.00000+exp(( - 1.00000*(STATES[7]+34.0000))/4.00000));
ALGEBRAIC[23] = (( 0.500000*CONSTANTS[45]*CONSTANTS[46])/CONSTANTS[47])*log(CONSTANTS[51]/STATES[11]);
ALGEBRAIC[56] = CONSTANTS[73]*(STATES[7] - ALGEBRAIC[23]);
ALGEBRAIC[57] = CONSTANTS[74]*(CONSTANTS[75]+ STATES[22]*(1.00000 - CONSTANTS[75]))*STATES[23]*(STATES[7] - ALGEBRAIC[21]);
ALGEBRAIC[58] = 0.0330000*exp(- STATES[7]/17.0000);
ALGEBRAIC[59] = 33.0000/(1.00000+exp( - 0.125000*(STATES[7]+10.0000)));
ALGEBRAIC[60] = ( (( CONSTANTS[76]*STATES[8])/(CONSTANTS[77]+STATES[8]))*STATES[10])/(CONSTANTS[78]+STATES[10]);
ALGEBRAIC[61] = ( (1.00000 - CONSTANTS[83])*CONSTANTS[79]*( exp(( CONSTANTS[82]*(CONSTANTS[80] - 2.00000)*STATES[7]*CONSTANTS[47])/( CONSTANTS[45]*CONSTANTS[46]))*pow(STATES[10], CONSTANTS[80])*CONSTANTS[51] - exp(( (CONSTANTS[82] - 1.00000)*(CONSTANTS[80] - 2.00000)*STATES[7]*CONSTANTS[47])/( CONSTANTS[45]*CONSTANTS[46]))*pow(CONSTANTS[50], CONSTANTS[80])*STATES[11]))/( (1.00000+ CONSTANTS[81]*( STATES[11]*pow(CONSTANTS[50], CONSTANTS[80])+ CONSTANTS[51]*pow(STATES[10], CONSTANTS[80])))*(1.00000+STATES[11]/0.00690000));
ALGEBRAIC[62] = ( CONSTANTS[83]*CONSTANTS[79]*( exp(( CONSTANTS[82]*(CONSTANTS[80] - 2.00000)*STATES[7]*CONSTANTS[47])/( CONSTANTS[45]*CONSTANTS[46]))*pow(STATES[10], CONSTANTS[80])*CONSTANTS[51] - exp(( (CONSTANTS[82] - 1.00000)*(CONSTANTS[80] - 2.00000)*STATES[7]*CONSTANTS[47])/( CONSTANTS[45]*CONSTANTS[46]))*pow(CONSTANTS[50], CONSTANTS[80])*STATES[17]))/( (1.00000+ CONSTANTS[81]*( STATES[17]*pow(CONSTANTS[50], CONSTANTS[80])+ CONSTANTS[51]*pow(STATES[10], CONSTANTS[80])))*(1.00000+STATES[17]/0.00690000));
ALGEBRAIC[63] = ALGEBRAIC[61]+ALGEBRAIC[62];
ALGEBRAIC[64] = STATES[11]+ STATES[24]*CONSTANTS[128]+ CONSTANTS[84]*CONSTANTS[85]+CONSTANTS[84];
ALGEBRAIC[65] = (CONSTANTS[89]==0.00000 ? (STATES[11]/ALGEBRAIC[64])*CONSTANTS[87] - (( STATES[24]*CONSTANTS[128])/ALGEBRAIC[64])*CONSTANTS[88] : ( (STATES[11]/ALGEBRAIC[64])*CONSTANTS[87])/(1.00000+STATES[24]/CONSTANTS[90]) - (( STATES[24]*CONSTANTS[128])/ALGEBRAIC[64])*CONSTANTS[88]);
ALGEBRAIC[66] = CONSTANTS[91]*(STATES[24] - STATES[25]);
ALGEBRAIC[68] = STATES[11]/(STATES[11]+CONSTANTS[97]);
ALGEBRAIC[69] = STATES[17]/(STATES[17]+CONSTANTS[98]);
ALGEBRAIC[70] = ALGEBRAIC[68]+ (1.00000 - ALGEBRAIC[68])*ALGEBRAIC[69];
ALGEBRAIC[71] = 500.000*pow(ALGEBRAIC[70], 2.00000);
ALGEBRAIC[72] = 60.0000+ 500.000*pow(ALGEBRAIC[70], 2.00000);
ALGEBRAIC[73] = (CONDVAR[32]<0.00000 ? 5.00000 : 1.00000);
ALGEBRAIC[74] = (1.00000 - STATES[26]) - STATES[27];
ALGEBRAIC[75] = ( pow(STATES[26]/(STATES[26]+0.250000), 2.00000)*CONSTANTS[96]+CONSTANTS[95])*STATES[25];
ALGEBRAIC[6] = (CONDVAR[7]>0.00000 ? (STATES[3]+CONSTANTS[20])/(0.460000+CONSTANTS[20]) : (CONSTANTS[20]+0.550000)*1.00000);
ALGEBRAIC[76] = ( CONSTANTS[30]*STATES[1])/( ALGEBRAIC[6]*STATES[6]);
ALGEBRAIC[77] = (CONDVAR[33]<=0.00000 ? CONSTANTS[109] : CONDVAR[34]<=0.00000 ? pow(CONSTANTS[109], ALGEBRAIC[76]) : 1.00000);
ALGEBRAIC[78] = CONSTANTS[119]*(STATES[30]+20.0000)+ CONSTANTS[121]*(STATES[30] - CONSTANTS[122]);
ALGEBRAIC[79] = - CONSTANTS[118]*(STATES[7] - STATES[30]);
ALGEBRAIC[4] = ( pow(STATES[6]/CONSTANTS[30], CONSTANTS[8])*(1.00000+pow(CONSTANTS[9], CONSTANTS[8])))/(pow(STATES[6]/CONSTANTS[30], CONSTANTS[8])+pow(CONSTANTS[9], CONSTANTS[8]));
ALGEBRAIC[5] = (CONDVAR[5]<0.00000 ? 0.00000 : CONDVAR[6]<0.00000 ? CONSTANTS[31]*STATES[3]+CONSTANTS[32] : 1.00000);
ALGEBRAIC[0] = (CONDVAR[2]<=0.00000 ? CONSTANTS[21] - ( CONSTANTS[22]*STATES[0])/CONSTANTS[13] : CONDVAR[3]<=0.00000&&CONDVAR[4]<0.00000 ? ( (CONSTANTS[24] - CONSTANTS[23])*STATES[0])/CONSTANTS[123]+CONSTANTS[23] : CONSTANTS[24]/pow(1.00000+( CONSTANTS[29]*(STATES[0] - CONSTANTS[123]))/CONSTANTS[13], CONSTANTS[28]));
ALGEBRAIC[82] = CONSTANTS[10]*CONSTANTS[11]*ALGEBRAIC[0]*CONSTANTS[12]*ALGEBRAIC[14];
ALGEBRAIC[83] = CONSTANTS[11]*ALGEBRAIC[0]*(1.00000 - CONSTANTS[10]*CONSTANTS[12]*ALGEBRAIC[14]);
ALGEBRAIC[84] = ALGEBRAIC[82]*ALGEBRAIC[4]*ALGEBRAIC[5]*ALGEBRAIC[6]*(1.00000 - STATES[1]) - ALGEBRAIC[83]*STATES[1];
ALGEBRAIC[7] = STATES[4]+STATES[5];
ALGEBRAIC[3] = CONSTANTS[6]*(exp( CONSTANTS[5]*STATES[5]) - 1.00000);
ALGEBRAIC[81] = ALGEBRAIC[3];
ALGEBRAIC[85] = (CONSTANTS[0]==1.00000&&CONDVAR[0]>0.00000&&CONDVAR[1]<=0.00000 ? 1.00000 : 0.00000);
ALGEBRAIC[86] = (ALGEBRAIC[85]==1.00000 ? - ( CONSTANTS[7]*ALGEBRAIC[84]*ALGEBRAIC[17]+ ALGEBRAIC[9]*ALGEBRAIC[10]*pow(STATES[0], 2.00000)+ CONSTANTS[3]*CONSTANTS[4]*exp( CONSTANTS[3]*STATES[4])*STATES[2])/( CONSTANTS[7]*STATES[1]*ALGEBRAIC[18]+ALGEBRAIC[10]) : - ( CONSTANTS[7]*ALGEBRAIC[84]*ALGEBRAIC[17]+ ALGEBRAIC[9]*ALGEBRAIC[10]*pow(STATES[0], 2.00000)+ ( CONSTANTS[3]*CONSTANTS[4]*exp( CONSTANTS[3]*STATES[4])+ CONSTANTS[5]*CONSTANTS[6]*exp( CONSTANTS[5]*STATES[5]))*STATES[2])/( CONSTANTS[7]*STATES[1]*ALGEBRAIC[18]+ALGEBRAIC[10]));
ALGEBRAIC[87] = (ALGEBRAIC[85]==1.00000 ? ( CONSTANTS[1]*CONSTANTS[2]*exp( CONSTANTS[1]*(STATES[4] - STATES[3]))*STATES[0])/( CONSTANTS[1]*CONSTANTS[2]*exp( CONSTANTS[1]*(STATES[4] - STATES[3]))+ CONSTANTS[3]*CONSTANTS[4]*exp( CONSTANTS[3]*STATES[4])) : ( CONSTANTS[1]*CONSTANTS[2]*exp( CONSTANTS[1]*(STATES[4] - STATES[3]))*STATES[0])/( CONSTANTS[1]*CONSTANTS[2]*exp( CONSTANTS[1]*(STATES[4] - STATES[3]))+ CONSTANTS[3]*CONSTANTS[4]*exp( CONSTANTS[3]*STATES[4])+ CONSTANTS[5]*CONSTANTS[6]*exp( CONSTANTS[5]*STATES[5])));
ALGEBRAIC[88] = (ALGEBRAIC[12]==0.00000 ? ALGEBRAIC[87] : STATES[2]);
ALGEBRAIC[89] = (ALGEBRAIC[85]==1.00000 ? 0.00000 : ALGEBRAIC[85]==0.00000&&ALGEBRAIC[12]==0.00000 ? - ALGEBRAIC[87] : ALGEBRAIC[85]==0.00000&&ALGEBRAIC[12] != 0.00000 ? - STATES[2] : 0.0/0.0);
}
void
getStateInformation(double* SI)
{
SI[0] = 1.0;
SI[1] = 1.0;
SI[2] = 1.0;
SI[3] = 1.0;
SI[4] = 1.0;
SI[5] = 1.0;
SI[6] = 1.0;
SI[7] = 1.0;
SI[8] = 1.0;
SI[9] = 1.0;
SI[10] = 1.0;
SI[11] = 1.0;
SI[12] = 1.0;
SI[13] = 1.0;
SI[14] = 1.0;
SI[15] = 1.0;
SI[16] = 1.0;
SI[17] = 1.0;
SI[18] = 1.0;
SI[19] = 1.0;
SI[20] = 1.0;
SI[21] = 1.0;
SI[22] = 1.0;
SI[23] = 1.0;
SI[24] = 1.0;
SI[25] = 1.0;
SI[26] = 1.0;
SI[27] = 1.0;
SI[28] = 1.0;
SI[29] = 1.0;
SI[30] = 1.0;
}
void
computeRoots(double VOI, double* CONSTANTS, double* RATES, double* OLDRATES, double* STATES,
double* OLDSTATES, double* ALGEBRAIC, double* CONDVARS)
{
CONDVAR[0] = ALGEBRAIC[81] - CONSTANTS[17];
CONDVAR[1] = ALGEBRAIC[7] - CONSTANTS[18]*(1.00000+0.000100000);
CONDVAR[2] = STATES[0] - 0.00000;
CONDVAR[3] = STATES[0] - CONSTANTS[123];
CONDVAR[4] = 0.00000 - STATES[0];
CONDVAR[5] = ( CONSTANTS[31]*STATES[3]+CONSTANTS[32]) - 0.00000;
CONDVAR[6] = ( CONSTANTS[31]*STATES[3]+CONSTANTS[32]) - 1.00000;
CONDVAR[7] = STATES[3] - 0.550000;
CONDVAR[8] = VOI - CONSTANTS[33];
CONDVAR[9] = VOI - CONSTANTS[34];
CONDVAR[10] = ((VOI - CONSTANTS[33]) - floor((VOI - CONSTANTS[33])/CONSTANTS[19])*CONSTANTS[19]) - CONSTANTS[35];
CONDVAR[11] = STATES[0] - 0.00000;
CONDVAR[12] = STATES[0] - 0.00000;
CONDVAR[13] = STATES[2] - STATES[0];
CONDVAR[14] = STATES[2] - STATES[0];
CONDVAR[15] = STATES[0] - 0.00000;
CONDVAR[16] = - CONSTANTS[13] - STATES[0];
CONDVAR[17] = STATES[0] - 0.00000;
CONDVAR[18] = 0.00000 - STATES[0];
CONDVAR[19] = STATES[0] - CONSTANTS[124];
CONDVAR[20] = STATES[0] - - CONSTANTS[13];
CONDVAR[21] = - CONSTANTS[13] - STATES[0];
CONDVAR[22] = STATES[0] - 0.00000;
CONDVAR[23] = 0.00000 - STATES[0];
CONDVAR[24] = STATES[0] - CONSTANTS[124];
CONDVAR[25] = VOI - CONSTANTS[33];
CONDVAR[26] = VOI - CONSTANTS[34];
CONDVAR[27] = ((VOI - CONSTANTS[33]) - floor((VOI - CONSTANTS[33])/CONSTANTS[19])*CONSTANTS[19]) - CONSTANTS[35];
CONDVAR[28] = fabs(ALGEBRAIC[36]) - CONSTANTS[60];
CONDVAR[29] = fabs(ALGEBRAIC[50]) - 0.000100000;
CONDVAR[30] = fabs(ALGEBRAIC[50]) - 0.000100000;
CONDVAR[31] = fabs(ALGEBRAIC[53]) - CONSTANTS[72];
CONDVAR[32] = STATES[7] - - 50.0000;
CONDVAR[33] = ALGEBRAIC[76] - 0.00000;
CONDVAR[34] = ALGEBRAIC[76] - 1.00000;
}