Generated Code
The following is c_ida code generated by the CellML API from this CellML file. (Back to language selection)
The raw code is available.
/*
There are a total of 25 entries in the algebraic variable array.
There are a total of 8 entries in each of the rate and state variable arrays.
There are a total of 24 entries in the constant variable array.
*/
/*
* VOI is time in component environment (millisecond).
* STATES[0] is V in component membrane (millivolt).
* CONSTANTS[0] is R in component membrane (joule_per_kilomole_kelvin).
* CONSTANTS[1] is T in component membrane (kelvin).
* CONSTANTS[2] is F in component membrane (coulomb_per_mole).
* CONSTANTS[3] is C in component membrane (microF_per_cm2).
* ALGEBRAIC[0] is I_stim in component membrane (microA_per_cm2).
* ALGEBRAIC[1] is i_Na in component fast_sodium_current (microA_per_cm2).
* ALGEBRAIC[9] is i_si in component slow_inward_current (microA_per_cm2).
* ALGEBRAIC[23] is i_K in component time_dependent_potassium_current (microA_per_cm2).
* ALGEBRAIC[24] is i_K1 in component time_independent_potassium_current (microA_per_cm2).
* ALGEBRAIC[21] is i_Kp in component plateau_potassium_current (microA_per_cm2).
* ALGEBRAIC[22] is i_b in component background_current (microA_per_cm2).
* CONSTANTS[4] is stim_start in component membrane (millisecond).
* CONSTANTS[5] is stim_end in component membrane (millisecond).
* CONSTANTS[6] is stim_period in component membrane (millisecond).
* CONSTANTS[7] is stim_duration in component membrane (millisecond).
* CONSTANTS[8] is stim_amplitude in component membrane (microA_per_cm2).
* CONSTANTS[9] is g_Na in component fast_sodium_current (milliS_per_cm2).
* CONSTANTS[18] is E_Na in component fast_sodium_current (millivolt).
* CONSTANTS[10] is Nao in component ionic_concentrations (millimolar).
* CONSTANTS[11] is Nai in component ionic_concentrations (millimolar).
* STATES[1] is m in component fast_sodium_current_m_gate (dimensionless).
* STATES[2] is h in component fast_sodium_current_h_gate (dimensionless).
* STATES[3] is j in component fast_sodium_current_j_gate (dimensionless).
* ALGEBRAIC[2] is alpha_m in component fast_sodium_current_m_gate (per_millisecond).
* ALGEBRAIC[3] is beta_m in component fast_sodium_current_m_gate (per_millisecond).
* ALGEBRAIC[4] is alpha_h in component fast_sodium_current_h_gate (per_millisecond).
* ALGEBRAIC[5] is beta_h in component fast_sodium_current_h_gate (per_millisecond).
* ALGEBRAIC[6] is alpha_j in component fast_sodium_current_j_gate (per_millisecond).
* ALGEBRAIC[7] is beta_j in component fast_sodium_current_j_gate (per_millisecond).
* ALGEBRAIC[8] is E_si in component slow_inward_current (millivolt).
* STATES[4] is Cai in component intracellular_calcium_concentration (millimolar).
* STATES[5] is d in component slow_inward_current_d_gate (dimensionless).
* STATES[6] is f in component slow_inward_current_f_gate (dimensionless).
* ALGEBRAIC[10] is alpha_d in component slow_inward_current_d_gate (per_millisecond).
* ALGEBRAIC[11] is beta_d in component slow_inward_current_d_gate (per_millisecond).
* ALGEBRAIC[12] is alpha_f in component slow_inward_current_f_gate (per_millisecond).
* ALGEBRAIC[13] is beta_f in component slow_inward_current_f_gate (per_millisecond).
* CONSTANTS[19] is g_K in component time_dependent_potassium_current (milliS_per_cm2).
* CONSTANTS[20] is E_K in component time_dependent_potassium_current (millivolt).
* CONSTANTS[12] is PR_NaK in component time_dependent_potassium_current (dimensionless).
* CONSTANTS[13] is Ko in component ionic_concentrations (millimolar).
* CONSTANTS[14] is Ki in component ionic_concentrations (millimolar).
* STATES[7] is X in component time_dependent_potassium_current_X_gate (dimensionless).
* ALGEBRAIC[16] is Xi in component time_dependent_potassium_current_Xi_gate (dimensionless).
* ALGEBRAIC[14] is alpha_X in component time_dependent_potassium_current_X_gate (per_millisecond).
* ALGEBRAIC[15] is beta_X in component time_dependent_potassium_current_X_gate (per_millisecond).
* CONSTANTS[21] is E_K1 in component time_independent_potassium_current (millivolt).
* CONSTANTS[22] is g_K1 in component time_independent_potassium_current (milliS_per_cm2).
* ALGEBRAIC[19] is K1_infinity in component time_independent_potassium_current_K1_gate (dimensionless).
* ALGEBRAIC[17] is alpha_K1 in component time_independent_potassium_current_K1_gate (per_millisecond).
* ALGEBRAIC[18] is beta_K1 in component time_independent_potassium_current_K1_gate (per_millisecond).
* CONSTANTS[23] is E_Kp in component plateau_potassium_current (millivolt).
* CONSTANTS[15] is g_Kp in component plateau_potassium_current (milliS_per_cm2).
* ALGEBRAIC[20] is Kp in component plateau_potassium_current (dimensionless).
* CONSTANTS[16] is E_b in component background_current (millivolt).
* CONSTANTS[17] is g_b in component background_current (milliS_per_cm2).
* RATES[0] is d/dt V in component membrane (millivolt).
* RATES[1] is d/dt m in component fast_sodium_current_m_gate (dimensionless).
* RATES[2] is d/dt h in component fast_sodium_current_h_gate (dimensionless).
* RATES[3] is d/dt j in component fast_sodium_current_j_gate (dimensionless).
* RATES[5] is d/dt d in component slow_inward_current_d_gate (dimensionless).
* RATES[6] is d/dt f in component slow_inward_current_f_gate (dimensionless).
* RATES[7] is d/dt X in component time_dependent_potassium_current_X_gate (dimensionless).
* RATES[4] is d/dt Cai in component intracellular_calcium_concentration (millimolar).
* There are a total of 8 condition variables.
*/
void
initConsts(double* CONSTANTS, double* RATES, double *STATES)
{
STATES[0] = -84.3801107371;
CONSTANTS[0] = 8314;
CONSTANTS[1] = 310;
CONSTANTS[2] = 96484.6;
CONSTANTS[3] = 1;
CONSTANTS[4] = 100;
CONSTANTS[5] = 9000;
CONSTANTS[6] = 1000;
CONSTANTS[7] = 2;
CONSTANTS[8] = -25.5;
CONSTANTS[9] = 23;
CONSTANTS[10] = 140;
CONSTANTS[11] = 18;
STATES[1] = 0.00171338077730188;
STATES[2] = 0.982660523699656;
STATES[3] = 0.989108212766685;
STATES[4] = 0.00017948816388306;
STATES[5] = 0.00302126301779861;
STATES[6] = 0.999967936476325;
CONSTANTS[12] = 0.01833;
CONSTANTS[13] = 5.4;
CONSTANTS[14] = 145;
STATES[7] = 0.0417603108167287;
CONSTANTS[15] = 0.0183;
CONSTANTS[16] = -59.87;
CONSTANTS[17] = 0.03921;
CONSTANTS[18] = (( CONSTANTS[0]*CONSTANTS[1])/CONSTANTS[2])*log(CONSTANTS[10]/CONSTANTS[11]);
CONSTANTS[19] = 0.282000* pow((CONSTANTS[13]/5.40000), 1.0 / 2);
CONSTANTS[20] = (( CONSTANTS[0]*CONSTANTS[1])/CONSTANTS[2])*log((CONSTANTS[13]+ CONSTANTS[12]*CONSTANTS[10])/(CONSTANTS[14]+ CONSTANTS[12]*CONSTANTS[11]));
CONSTANTS[21] = (( CONSTANTS[0]*CONSTANTS[1])/CONSTANTS[2])*log(CONSTANTS[13]/CONSTANTS[14]);
CONSTANTS[22] = 0.604700* pow((CONSTANTS[13]/5.40000), 1.0 / 2);
CONSTANTS[23] = CONSTANTS[21];
RATES[0] = 0.1001;
RATES[1] = 0.1001;
RATES[2] = 0.1001;
RATES[3] = 0.1001;
RATES[5] = 0.1001;
RATES[6] = 0.1001;
RATES[7] = 0.1001;
RATES[4] = 0.1001;
}
void
computeResiduals(double VOI, double* CONSTANTS, double* RATES, double* OLDRATES, double* STATES,
double* OLDSTATES, double* ALGEBRAIC, double* CONDVARS)
{
resid[0] = RATES[0] - (- 1.00000/CONSTANTS[3])*(ALGEBRAIC[0]+ALGEBRAIC[1]+ALGEBRAIC[9]+ALGEBRAIC[23]+ALGEBRAIC[24]+ALGEBRAIC[21]+ALGEBRAIC[22]);
resid[1] = RATES[1] - ALGEBRAIC[2]*(1.00000 - STATES[1]) - ALGEBRAIC[3]*STATES[1];
resid[2] = RATES[2] - ALGEBRAIC[4]*(1.00000 - STATES[2]) - ALGEBRAIC[5]*STATES[2];
resid[3] = RATES[3] - ALGEBRAIC[6]*(1.00000 - STATES[3]) - ALGEBRAIC[7]*STATES[3];
resid[4] = RATES[5] - ALGEBRAIC[10]*(1.00000 - STATES[5]) - ALGEBRAIC[11]*STATES[5];
resid[5] = RATES[6] - ALGEBRAIC[12]*(1.00000 - STATES[6]) - ALGEBRAIC[13]*STATES[6];
resid[6] = RATES[7] - ALGEBRAIC[14]*(1.00000 - STATES[7]) - ALGEBRAIC[15]*STATES[7];
resid[7] = RATES[4] - (- 0.000100000/1.00000)*ALGEBRAIC[9]+ 0.0700000*(0.000100000 - STATES[4]);
}
void
computeVariables(double VOI, double* CONSTANTS, double* RATES, double* STATES, double* ALGEBRAIC)
{
}
void
computeEssentialVariables(double VOI, double* CONSTANTS, double* RATES, double* STATES, double* ALGEBRAIC)
{
ALGEBRAIC[0] = (CONDVAR[0]>=0.00000&&CONDVAR[1]<=0.00000&&CONDVAR[2]<=0.00000 ? CONSTANTS[8] : 0.00000);
ALGEBRAIC[1] = CONSTANTS[9]*pow(STATES[1], 3.00000)*STATES[2]*STATES[3]*(STATES[0] - CONSTANTS[18]);
ALGEBRAIC[2] = ( 0.320000*(STATES[0]+47.1300))/(1.00000 - exp( - 0.100000*(STATES[0]+47.1300)));
ALGEBRAIC[3] = 0.0800000*exp(- STATES[0]/11.0000);
ALGEBRAIC[4] = (CONDVAR[3]<0.00000 ? 0.135000*exp((80.0000+STATES[0])/- 6.80000) : 0.00000);
ALGEBRAIC[5] = (CONDVAR[4]<0.00000 ? 3.56000*exp( 0.0790000*STATES[0])+ 310000.*exp( 0.350000*STATES[0]) : 1.00000/( 0.130000*(1.00000+exp((STATES[0]+10.6600)/- 11.1000))));
ALGEBRAIC[6] = (CONDVAR[5]<0.00000 ? ( ( - 127140.*exp( 0.244400*STATES[0]) - 3.47400e-05*exp( - 0.0439100*STATES[0]))*(STATES[0]+37.7800))/(1.00000+exp( 0.311000*(STATES[0]+79.2300))) : 0.00000);
ALGEBRAIC[7] = (CONDVAR[6]<0.00000 ? ( 0.121200*exp( - 0.0105200*STATES[0]))/(1.00000+exp( - 0.137800*(STATES[0]+40.1400))) : ( 0.300000*exp( - 2.53500e-07*STATES[0]))/(1.00000+exp( - 0.100000*(STATES[0]+32.0000))));
ALGEBRAIC[8] = 7.70000 - 13.0287*log(STATES[4]/1.00000);
ALGEBRAIC[9] = 0.0900000*STATES[5]*STATES[6]*(STATES[0] - ALGEBRAIC[8]);
ALGEBRAIC[10] = ( 0.0950000*exp( - 0.0100000*(STATES[0] - 5.00000)))/(1.00000+exp( - 0.0720000*(STATES[0] - 5.00000)));
ALGEBRAIC[11] = ( 0.0700000*exp( - 0.0170000*(STATES[0]+44.0000)))/(1.00000+exp( 0.0500000*(STATES[0]+44.0000)));
ALGEBRAIC[12] = ( 0.0120000*exp( - 0.00800000*(STATES[0]+28.0000)))/(1.00000+exp( 0.150000*(STATES[0]+28.0000)));
ALGEBRAIC[13] = ( 0.00650000*exp( - 0.0200000*(STATES[0]+30.0000)))/(1.00000+exp( - 0.200000*(STATES[0]+30.0000)));
ALGEBRAIC[14] = ( 0.000500000*exp( 0.0830000*(STATES[0]+50.0000)))/(1.00000+exp( 0.0570000*(STATES[0]+50.0000)));
ALGEBRAIC[15] = ( 0.00130000*exp( - 0.0600000*(STATES[0]+20.0000)))/(1.00000+exp( - 0.0400000*(STATES[0]+20.0000)));
ALGEBRAIC[20] = 1.00000/(1.00000+exp((7.48800 - STATES[0])/5.98000));
ALGEBRAIC[21] = CONSTANTS[15]*ALGEBRAIC[20]*(STATES[0] - CONSTANTS[23]);
ALGEBRAIC[22] = CONSTANTS[17]*(STATES[0] - CONSTANTS[16]);
ALGEBRAIC[16] = (CONDVAR[7]>0.00000 ? ( 2.83700*(exp( 0.0400000*(STATES[0]+77.0000)) - 1.00000))/( (STATES[0]+77.0000)*exp( 0.0400000*(STATES[0]+35.0000))) : 1.00000);
ALGEBRAIC[23] = CONSTANTS[19]*STATES[7]*ALGEBRAIC[16]*(STATES[0] - CONSTANTS[20]);
ALGEBRAIC[17] = 1.02000/(1.00000+exp( 0.238500*((STATES[0] - CONSTANTS[21]) - 59.2150)));
ALGEBRAIC[18] = ( 0.491240*exp( 0.0803200*((STATES[0]+5.47600) - CONSTANTS[21]))+ 1.00000*exp( 0.0617500*(STATES[0] - (CONSTANTS[21]+594.310))))/(1.00000+exp( - 0.514300*((STATES[0] - CONSTANTS[21])+4.75300)));
ALGEBRAIC[19] = ALGEBRAIC[17]/(ALGEBRAIC[17]+ALGEBRAIC[18]);
ALGEBRAIC[24] = CONSTANTS[22]*ALGEBRAIC[19]*(STATES[0] - CONSTANTS[21]);
}
void
getStateInformation(double* SI)
{
SI[0] = 1.0;
SI[1] = 1.0;
SI[2] = 1.0;
SI[3] = 1.0;
SI[4] = 1.0;
SI[5] = 1.0;
SI[6] = 1.0;
SI[7] = 1.0;
}
void
computeRoots(double VOI, double* CONSTANTS, double* RATES, double* OLDRATES, double* STATES,
double* OLDSTATES, double* ALGEBRAIC, double* CONDVARS)
{
CONDVAR[0] = VOI - CONSTANTS[4];
CONDVAR[1] = VOI - CONSTANTS[5];
CONDVAR[2] = ((VOI - CONSTANTS[4]) - floor((VOI - CONSTANTS[4])/CONSTANTS[6])*CONSTANTS[6]) - CONSTANTS[7];
CONDVAR[3] = STATES[0] - - 40.0000;
CONDVAR[4] = STATES[0] - - 40.0000;
CONDVAR[5] = STATES[0] - - 40.0000;
CONDVAR[6] = STATES[0] - - 40.0000;
CONDVAR[7] = STATES[0] - - 100.000;
}