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You are here: Home › Exposures › Lemaire, Tobin, Greller, Cho, Suva, 2004 › Main Model + Removing Osteoclasts

Model Mathematics

Component: environment

Component: R

\frac{d}{d time} (R) = DR pi_C - (\frac{DB}{pi_C} R)

Component: B

\frac{d}{d time} (B) = \frac{DB}{pi_C} R - (kB B)

Component: C

\frac{d}{d time} (C) = (DC pi_L - (DA pi_C C)) + f f = \{\begin{matrix} - 0.00029 if time > 20 \land time ≦ 80 \\ 0 otherwise \end{matrix}

Component: pi_L

pi_L = \frac{\frac{\frac{k3}{k4} KLP}{1} pi_P B}{1 + \frac{k3 K}{k4} + \frac{k1}{k2 ko} (\frac{\frac{KOP}{1}}{pi_P} R + Io)} (1 + \frac{IL}{rL})

Component: model_parameters

DB = f0 dB pi_C = \frac{C + f0 C_s}{C + C_s} pi_P = \frac{P + P_0}{P + P_s} P = \frac{IP}{kP} P_0 = \frac{SP}{kP} P_s = \frac{k6}{k5}

Model Curation

Curation Status
JSim
COR
OpenCell

Source: Derived from workspace Lemaire, Tobin, Greller, Cho, Suva, 2004 at changeset 2e06d5a02819.

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License: This work is licensed under a Creative Commons Attribution 3.0 Unported License.