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Flynn, Green, Pedley, Boxer, Dearling, Watson, Boden, Begent, 2002
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A Model-Based Approach for the Optimization of Radioimmunotherapy through Antibody Design and Radionuclide Selection
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Model Mathematics
Component based math viewer is available
Component: environment
Component: B
d
d
time
B
=
-
lamda_Bo
+
lamda_Vi
B
Component: V
d
d
time
V
=
lamda_Vi
B
-
lamda_Vo
+
lamda_Ho
V
Component: H
d
d
time
H
=
-
lamda_Hi
V
+
lamda_Ho
H
Component: antibody_dose_rate
RV
=
A0
Eav
n_beta
K
V
phi
VV
+
H
phi
VH
RH
=
A0
Eav
n_beta
K
V
phi
HV
+
H
phi
HH
Component: S
S
=
ⅇ
-
alpha
D
RE
Component: response_models
total_probability
=
2.0
P
∫
0
T
R
ⅇ
-
mu
T
-
time
d
time
probability_of_typeB_damage
=
2.0
P
2.0
∫
0
time
∫
0
T
ⅇ
-
mu
T
-
time
d
T
d
time
probability_of_typeB_damage
=
alpha
∫
0
time
R
d
time
Component: model_parameters
Source
Derived from workspace
Flynn, Green, Pedley, Boxer, Dearling, Watson, Boden, Begent, 2002
at changeset
f6e356c29a7d
.
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This work is licensed under a
Creative Commons Attribution 3.0 Unported License
.
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A Model-Based Approach for the Optimization of Radioimmunotherapy through Antibody Design and Radionuclide Selection