Department of Physiology, Anatomy & Genetics, University of Oxford
A multiple stimulus protocol component has been added to this model to allow simulations of trains of action potentials. Several variables have also been given cmeta:ids to allow them to be referenced in a PCEnv session file.
Circulation Research
2007-10-30T11:32:02+13:00
Department of Physiology, Anatomy & Genetics
Oxford University
John
Rice
J
James Lawson
Richard
Lawson
James
1999-03-19 00:00
O'Rorke
Brian
bdf15
10
0.001
50000
Mechanisms of Altered Excitation-Contraction Coupling in Canine Tachycardia-Induced Heart Failure, II Model Studies
586
84
571
electrophysiology
tachycardia
calcium dynamics
cardiac
heart failure
canine
excitation-contraction coupling
ventricular myocyte
Ventricular Myocyte
J
Penny
Noble
S
M
Jafri
This is the CellML description of Winslow et al's mathematical model of ionic fluxes and Ca regulation in normal and failing ventricular myocytes. This model is derived from Jafri et al's guinea pig ventricular model (1998) with modifications to better represent the conditions in a canine midmyocardial ventricular cell.
2008-02-25T12:32:09+13:00
units checked, curated
This model has been curated by Penny Noble and is known to run in PCEnv and COR. It is able to produce the results of the model published in the Matsuoka 2003 paper but still contains some unit discrepancies.
2006-05-15T00:00:00+00:00
10082479
Catherine Lloyd
Penny
Noble
J
penny.noble@dpag.ox.ac.uk
Raimond
Winslow
L
Eduardo
Marban
keyword