Model Mathematics

Component: environment

Component: membrane

dd time V = g_I sI 3.0 yI + g_T xT V_I - V + g_K xK 4.0 + g_P c Kp + c -1 V_K - V + g_L V_L - V g_I = 1 V_H_Na - V_H_K V_I - V_K g_T = 1 V_H_Na V_K - V_I V_H_K V_I - V_K Vs = 1 g_I V + 1 g_T

Component: sI_gate

alpha_m = 0.1 50.0 - Vs - 50.0 - Vs 10.0 beta_m = 4.0 25.0 - Vs 18.0 sI = alpha_m alpha_m + beta_m

Component: yI_gate

alpha_h = 0.07 25.0 - Vs 20.0 beta_h = 1.0 55.0 - Vs 10.0 + 1.0 dd time yI = ZI - yI tau_yI ZI = alpha_h alpha_h + beta_h tau_yI = 12.5 alpha_h + beta_h

Component: xT_gate

dd time xT = sT - xT tau_xT sT = 1.0 0.15 -50.0 - Vs + 1.0

Component: calcium_concentration

dd time c = rho K_c xT V_Ca - V - c

Component: xK_gate

alpha_n = 0.01 55.0 - Vs 55.0 - Vs 10.0 - 1.0 beta_n = 0.125 45.0 - Vs 80.0 dd time xK = sK - xK tau_xK sK = alpha_n alpha_n + beta_n tau_xK = 12.5 alpha_n + beta_n