C
C There are a total of 0 entries in the algebraic variable array.
C There are a total of 1 entries in each of the rate and state variable arrays.
C There are a total of 19 entries in the constant variable array.
C
C
C VOI is time in component environment (minute).
C CONSTS(16) is C in component C (nanomolar).
C CONSTS(1) is kf1 in component model_parameters (second_order_rate_constant).
C CONSTS(13) is kr1 in component model_parameters (first_order_rate_constant).
C CONSTS(14) is k_x1 in component model_parameters (first_order_rate_constant).
C CONSTS(2) is kt in component model_parameters (first_order_rate_constant).
C CONSTS(3) is ke in component model_parameters (first_order_rate_constant).
C CONSTS(4) is L in component model_parameters (nanomolar).
C CONSTS(17) is R in component R (nanomolar).
C CONSTS(15) is K_X in component D (per_nanomolar).
C CONSTS(18) is D in component D (nanomolar).
C CONSTS(5) is kx2 in component model_parameters (second_order_rate_constant).
C CONSTS(6) is k_x2 in component model_parameters (first_order_rate_constant).
C CONSTS(7) is R_initial in component R (nanomolar).
C CONSTS(8) is krec in component model_parameters (first_order_rate_constant).
C CONSTS(9) is kdeg in component model_parameters (first_order_rate_constant).
C STATES(1) is Ri in component Ri (nanomolar).
C CONSTS(19) is signal in component signal (dimensionless).
C CONSTS(10) is kappaE in component model_parameters (dimensionless).
C CONSTS(11) is Vs in component model_parameters (flux).
C CONSTS(12) is KD in component model_parameters (nanomolar).
C RATES(1) is d/dt Ri in component Ri (nanomolar).
C
      SUBROUTINE initConsts(CONSTS, RATES, STATES)
      REAL CONSTS(*), RATES(*), STATES(*)
      CONSTS(1) = 0.1
      CONSTS(2) = 0.005
      CONSTS(3) = 0.10
      CONSTS(4) = 0.01
      CONSTS(5) = 4.83
      CONSTS(6) = 0.016
      CONSTS(7) = 2000.0
      CONSTS(8) = 0.0
      CONSTS(9) = 0.05
      STATES(1) = 200.0
      CONSTS(10) = 0.20
      CONSTS(11) = 10.0
      CONSTS(12) = 1.0
      CONSTS(13) =  CONSTS(12)*CONSTS(1)
      CONSTS(14) =  0.0100000*CONSTS(13)
      CONSTS(15) = CONSTS(5)/(CONSTS(6)+CONSTS(14)+CONSTS(3))
CALL minimize(minfunc_0, CONSTS, VARIABLES, <VAR>)
      CONSTS(19) = (( 2.00000*CONSTS(18))/200.000)/(CONSTS(10)+( 2.00000*CONSTS(18))/200.000)
      RETURN
      END
      SUBROUTINE computeRates(VOI, CONSTS,  RATES, STATES, ALGBRC)
      REAL VOI, CONSTS(*), RATES(*), STATES(*), ALGBRC(*)
      RATES(1) =  CONSTS(2)*(CONSTS(17)+CONSTS(16)) -  (CONSTS(8)+CONSTS(9))*STATES(1)
      RETURN
      END
      SUBROUTINE computeVariables(VOI, CONSTS, RATES, STATES, ALGBRC)
      REAL VOI, CONSTS(*), RATES(*), STATES(*), ALGBRC(*)
      RETURN
      END
REAL FUNCTION minfunc_0(CONSTS, VARIABLES)
            REAL CONSTS(*), VARIABLES(*) 
      minfunc_0[1] = abs(CONSTS(16) - ( CONSTS(1)*CONSTS(4)*CONSTS(17))/(CONSTS(13)+CONSTS(2)+ (CONSTS(14)+CONSTS(3))*CONSTS(15)*CONSTS(17)))
      minfunc_0[2] = abs(CONSTS(18) -  CONSTS(15)*CONSTS(17)*CONSTS(16))
      minfunc_0[3] = abs(CONSTS(17) - (CONSTS(7) - (CONSTS(16)+ 2.00000*(CONSTS(3)/CONSTS(2))*(1.00000+CONSTS(8)/CONSTS(9))*CONSTS(18))))
      RETURN
      END