# Full List

Below is a listing of model exposures (100 per page | full list)

- A Quantitative Model of Human Jejunal Smooth Muscle Cell Electrophysiology
- An analysis of deformation-dependent electromechanical coupling in the mouse heart
- Davies ISAP 2012
- Ionic mechanisms for electrical heterogeneity between rabbit Purkinje fiber and ventricular cells
- Simulations of the effects of inositol 1,4,5-trisphosphate 3-kinase and 5-phosphatase activities on Ca2+ oscillations
- [Ca2+]i oscillations in sympathetic neurons: an experimental test of a theoretical model
- A model for pacemaking in substantia nigra neurons (A simple model based on a spherical geometry)
- A Primer on Modular Mass Action Modelling with CellML
- A single compartment model of pacemaking in dissasociated Substantia nigra neurons with hyperbolic tetrahedral geometry
- A Tutorial on Creating a Systems Model from SVPs
- Activation of the Liver Glycogen Phosphorylase by Ca2+ Oscillations: a Theoretical Study
- Adrian, Chandler, Hodgkin, 1970
- Voltage clamp experiments in striated muscle fibres
- Aguda, 1999
- A quantitative analysis of the kinetics of the G2 DNA damage checkpoint system
- Aguda, Tang, 1999
- The kinetic origins of the restriction point in the mammalian cell cycle
- Albrecht, Colegrove, Friel, 2002
- Differential Regulation of ER Ca2+ Uptake and Release Rates Accounts for Multiple Modes of Ca2+-induced Ca2+ Release
- Albrecht, Colegrove, Hongpaisan, Pivovarova, Andrews, Friel, 2001
- Multiple Modes of Calcium-induced Calcium Release in Sympathetic Neurons I: Attenuation of Endoplasmic Reticulum Ca2+ Accumulation at Low [Ca2+]i during Weak Depolarisation
- Alexander, Wahl, 2010
- Self-tolerance and Autoimmunity in a Regulatory T Cell Model
- An integrated model of eicosanoid metabolism and signaling based on lipidomics flux analysis
- An updated computational model of rabbit sinoatrial action potential to investigate the mechanisms of heart rate modulation.
- Andre playing with nested tasks in SED-ML
- Andre's Hodgkin & Huxley with CellML
- Andre's Hodgkin & Huxley with CellML
- Aon, Cortassa, 2002
- Coherent and robust modulation of a metabolic network by cytoskeletal organization and dynamics
- Arresting the mitotic oscillator and the control of cell proliferation: insights from a cascade model for cdc2 kinase activation
- Arresting the mitotic oscillator and the control of cell proliferation: insights from a cascade model for cdc2 kinase activation
- Aslanidi, Boyett, Dobrzynski, Li, Zhang, 2009
- Mechanisms of transition from normal to reentrant electrical activity in a model of rabbit atrial tissue: interaction of tissue heterogeneity and anisotropy
- Aslanidi, Stewart, Boyett, Zhang, 2009
- Optimal velocity and safety of discontinuous conduction through the heterogeneous Purkinje-ventricular junction
- Asthagiri, Lauffenburger, 2001
- A Compuational Study of Feedback Effects on Signal Dynamics in a Mitogen-Activated Protein Kinase (MAPK) Pathway Model
- Bagci, Vodovotz, Billiar, Ermentrout, Bahar, 2006
- Bistability in apoptosis: roles of bax, bcl-2, and mitochondrial permeability transition pores
- Bagci, Vodovotz, Billiar, Ermentrout, Bahar, 2008
- Computational insights on the competing effects of nitric oxide in regulating apoptosis
- Bakker, Mensonides, Teusink, van Hoek, Michels, Westerhoff, 2000
- Compartmentation protects trypanosomes from the dangerous design of glycolysis
- Bakker, Michels, Opperdoes, Westerhoff, 1997
- Glycolysis in Bloodstream Form Trypanosoma brucei Can Be Understood in Terms of the Kinetics of the Glycolytic Enzymes
- Barberis, Klipp, Vanoni, Alberghina, 2007
- Cell Size at S Phase Initiation: An Emergent Property of the G1/S Network
- Basket Catheter Emulator
- Baylor, Hollingworth, Chandler, 2002
- Comparison of Simulated and Measured Calcium Sparks in Intact Skeletal Muscle Fibers of the Frog
- Beard, 2005
- A biophysical model of the mitochondrial respiratory system and oxidative phosphorylation
- Ben-Tal, 2006
- Simplified models for gas exchange in the human lungs
- Benson, Aslanidi, Zhang, Holden, 2008
- The canine virtual ventricular wall: a platform for dissecting pharmacological effects on propagation and arrhythmogenesis
- Bernus, Wilders, Zemlin, Verschelde, Panfilov, 2002
- A computationally efficient electrophysiological model of human ventricular cells
- Bertram, Arnot, Zamponi, 2002
- Role for G protein G-beta-gamma isoform specificity in synaptic signal processing: a computational study
- Bertram, Pedersen, Luciani, Sherman, 2006
- A simplified model for mitochondrial ATP production
- Bertram, Previte, Sherman, Kinard, Satin, 2000
- The Phantom Burster Model for Pancreatic Beta Cells
- Bertram, Rhoads, Cimbora, 2008
- A phantom bursting mechanism for episodic bursting
- Bertram, Satin, Pedersen, Luciani, Sherman, 2007
- Intra- and inter-islet synchronization of metabolically driven insulin secretion
- Bertram, Satin, Zhang, Smolen, Sherman, 2004
- Calcium and Glycolysis Mediate Multiple Bursting Modes in Pancreatic Islets
- Bertram, Sherman, 2004
- A Calcium-based Phantom Bursting Model for Pancreatic Islets
- Bertram, Smolen, Sherman, Mears, Atwater, Martin, Soria, 1995
- A role for calcium release-activated current (CRAC) in cholinergic modulation of electrical activity in pancreatic beta-cells
- Bhalla, Iyengar, 1999
- Emergent Properties of Networks of Biological Signaling Pathways
- Bifurcation analysis of the regulatory modules of the mammalian G1/S transition
- Bindschadler, Sneyd, 2001
- A Bifurcation Analysis of Two Coupled Calcium Oscillators
- Bingzheng, Zhenye, Liansong, 1990
- A mathematical model of the regulation system of the secretion of glucocorticoids
- Bondarenko, Szigeti, Bett, Kim, Rasmusson, 2004
- Computer model of action potential of mouse ventricular myocytes
- Bonhoeffer, Rembiszewski, Ortiz, Nixon, 2000
- Risks and benefits of structured antiretroviral drug therapy interruptions in HIV-1 infection
- Borghans, Dupont, Goldbeter, 1997
- Complex intracellular calcium oscillations. A theoretical exploration of possible mechanisms
- Bornheimer, Maurya, Farquhar, Subramaniam, 2004
- Computational modeling reveals how interplay between components of a GTPase-cycle module regulates signal transduction
- Boyett, Zhang, Garny, Holden, 2001
- Control of the pacemaker activity of the sinoatrial node by intracellular Ca2+. Experiments and modelling
- Brightman, Fell, 2000
- Differential feedback regulation of the MAPK cascade underlies the quantitative differences in EGF and NGF signalling in PC12 cells.
- Brown, Choe, Shanahan, Czeisler, 1997
- A mathematical model of diurnal variations in human plasma melatonin levels
- Bueno, 2007
- Mathematical modeling and spectral simulation of genetic diseases in the human heart
- Bugbuster Systems Model
- Bugenhagen 2010
- Bugenhagen 2010
- Model of the overall baroreflex heart rate control system.
- Butera, Rinzel, Smith, 1999
- Models of Respiratory Rhythm Generation in the Pre-Botzinger Complex. II. Populations of Coupled Pacemaker Neurons
- Butera, Rinzel, Smith, 1999
- Models of Respiratory Rhythm Generation in the Pre-Botzinger Complex. I. Bursting Pacemaker Neurons
- Butera, Rinzel, Smith, 1999
- Models of Respiratory Rhythm Generation in the Pre-Botzinger Complex. II. Populations of Coupled Pacemaker Neurons
- Calzone, Thieffry, Tyson, Novak, 2007
- Dynamical modeling of syncytial mitotic cycles in Drosophila embryos
- Campbell, Chandra, 2006
- Functions of Stretch Activation in Heart Muscle
- Carro, Rodriguez, Laguna, Pueyo (2011)
- In this study, several modifications were introduced to a recently proposed human ventricular action potential (AP) model so as to render it suitable for the study of ventricular arrhythmias. These modifications were driven by new sets of experimental data available from the literature and the analysis of several well-established cellular arrhythmic risk biomarkers, namely AP duration at 90 per cent repolarization (APD90), AP triangulation, calcium dynamics, restitution properties, APD90 adaptation to abrupt heart rate changes, and rate dependence of intracellular sodium and calcium concentrations. The proposed methodology represents a novel framework for the development of cardiac cell models. Five stimulation protocols were applied to the original model and the ventricular AP model developed here to compute the described arrhythmic risk biomarkers. In addition, those models were tested in a one-dimensional fibre in which hyperkalaemia was simulated by increasing the extracellular potassium concentration, [K+]o. The effective refractory period (ERP), conduction velocity (CV) and the occurrence of APD alternans were investigated. Results show that modifications improved model behaviour as verified by: (i) AP triangulation well within experimental limits (the difference between APD at 50 and 90 per cent repolarization being 78.1 ms); (ii) APD90 rate adaptation dynamics characterized by fast and slow time constants within physiological ranges (10.1 and 105.9 ms); and (iii) maximum S1S2 restitution slope in accordance with experimental data (SS1S2=1.0). In simulated tissues under hyperkalaemic conditions, APD90 progressively shortened with the degree of hyperkalaemia, whereas ERP increased once a threshold in [K+]o was reached ([K+]o= 6 mM). CV decreased with [K+]o, and conduction was blocked for [K+]o>10.4 mM. APD90 alternans were observed for [K+]o>9.8 mM. Those results adequately reproduce experimental observations. This study demonstrated the value of basing the development of AP models on the computation of arrhythmic risk biomarkers, as opposed to joining together independently derived ion channel descriptions to produce a whole-cell AP model, with the new framework providing a better picture of the model performance under a variety of stimulation conditions. On top of replicating experimental data at single-cell level, the model developed here was able to predict the occurrence of APD90 alternans and areas of conduction block associated with high [K+]o in tissue, which is of relevance for the investigation of the arrhythmogenic substrate in ischaemic hearts.
- Cartwright, Husain, 1986
- A model for the control of testosterone secretion
- Cell Viability Models for Tissue Exposed to Ablative Temperatures
- Cell viability models for tissue exposed to ablative temperatures.
- Chang, Fujita, 1999
- Chang, Fujita, 1999
- A kinetic model of the thiazide-sensitive Na-Cl cotransporter
- Chang, Fujita, 1999
- A numerical model of the renal distal tubule
- Chang, Fujita, 2001
- A numerical model of acid-base transport in rat distal tubule
- Chassagnole, Rais, Quentin, Fell, Mazat, 2001
- An integrated study of Threonine-pathway enzyme kinetics in Escherichia coli
- Chay, 1997
- Effects of extracellular calcium on electrical bursting and intracellular and luminal calcium oscillations in insulin secreting pancreatic beta-cells
- Chay, Lee, Fan, 1995
- Appearance of Phase-locked Wenchbach-like Rhythms, Devil's Staircase and Universality in Intracellular Calcium Spikes in Non-excitable Cell Models
- Chen, Calzone, Csikasz-Nagy, Cross, Novak, Tyson, 2004
- Integrative Analysis of Cell Cycle Control in Budding Yeast
- Chen, Csikasz-Nagy, Gyorffy, Val, Novak, Tyson, 2000
- Kinetic Analysis of a Molecular Model of the Budding Yeast Cell Cycle
- Chen, Popel, 2006
- Theoretical analysis of biochemical pathways of nitric oxide release from vascular endothelial cells
- Chen, Popel, 2007
- Vascular and perivascular nitric oxide release and transport: biochemical pathways of neuronal nitric oxide synthase (NOS1) and endothelial nitric oxide synthase (NOS3)
- Cheng, Brown, Loeb, 2000
- Virtual muscle: a computational approach to understanding the effects of muscle properties on motor control
- Ciliberto, Novak, Tyson, 2003
- Mathematical Model of the Morphogenesis Checkpoint in Budding Yeast
- Ciliberto, Petrus, Tyson, Sible, 2003
- A kinetic model of the cyclin E/Cdk2 developmental timer in Xenopus
- Ciliberto, Tyson, 2000
- Mathematical Model for Early Development of the Sea Urchin Embryo
- Cl-/HCO3- Exchanger (AE1) Model
- Clancy, Rudy, 2001
- Cellular consequences of HERG mutations in the long QT syndrome: precursors to sudden cardiac death
- Clancy, Rudy, 2002
- Na Channel Mutation That Causes Both Brugada Syndrome and Long-QT Syndrome Phenotypes: A Simulation Study of Mechanism
- Cloutier, Bolger, Lowry, Wellstead, 2009
- An integrative dynamic model of brain energy metabolism using in vivo neurochemical measurements
- Cloutier, Wellstead, 2009
- The control systems structures of energy metabolism
- Colegrove, Albrecht, Friel, 2000
- Quantitive Analysis of Mitochondrial Ca2+ Uptake and Release Pathways in Sympathetic Neurons Reconstruction of the Recovery after Depolarisation-evoked [Ca2+] Elevations
- Collier et al (1996) Delta-Notch model
- Computational Mechanics of the Heart
- Computational models of ventricular- and atrial-like human induced pluripotent stem cell derived cardiomyocytes
- Computational models of ventricular- and atrial-like human induced pluripotent stem cell derived cardiomyocytes
- Conradie, Bruggeman, Ciliberto, Csikasz-Nagy, Novak, Westerhoff, Snoep,
- Restriction point control of the mammalian cell cycle via the cyclin E/Cdk2:p27 complex
- Cooling, Hunter, Crampin, 2008
- Cooling, Hunter, Crampin, 2009. Dual Calcium Protocol
- Cooling, Hunter, Crampin, 2009. Shen Calcium Protocol
- Cooling, Hunter, Crampin, 2009. Tomida Calcium Protocol
- Corrias, Buist, 2007
- Corrias, Buist, 2007
- Corrias, Buist, 2008
- Quantitative cellular description of gastric slow wave activity
- Cortassa et al. (2006) ECME model
- Cortassa, Aon, Marban, Winslow, O'Rourke, 2003
- An Integrated Model of Cardiac Mitrochondrial Energy Metabolism and Calcium Dynamics
- Cortassa, Aon, Winslow, O'Rourke, 2004
- A mitochondrial oscillator dependent on reactive oxygen species
- Costa, Holmes, McCulloch, 2001
- Modelling Cardiac Mechanical Properties In Three Dimensions
- Courtemanche, Ramirez, Nattel, 1998
- Ionic mechanisms underlying human atrial action potential properties: insights from a mathematical model
- Covering a broad dynamic range: information processing at the erythropoietin receptor
- Cronwright, Rohwer, Prior, 2002
- Metabolic Control Analysis of Glycerol Synthesis in Saccharomyces cerevisiae
- Csikasz-Nagy, Battogtokh, Chen, Novak, Tyson, 2006
- Analysis of a generic model of eukaryotic cell-cycle regulation: budding yeast taken from the original model code
- Cui, Kaandorp, 2006
- Mathematical modeling of calcium homeostasis in yeast cells
- Cui, Kaandorp, 2008
- Simulating Complex Calcium-Calcineurin Signaling Network
- Cui, Kaandorp, Lloyd, 2008
- Simulating in vitro transcriptional response of zinc homeostasis system in Escherichia coli
- Curien, Ravanel, Dumas, 2003
- A kinetic model of the branch-point between the methionine and threonine biosynthesis pathways in Arabidopsis thaliana
- Dash, Bassingthwaighte, 2004
- Blood HbO2 and HbCO2 dissociation curves at varied O2, CO2, pH, 2,3-DPG and temperature levels
- David Cumin PhD Model
- Dawson, Lea, Irvine, 2003
- Kinetic model of the inositol trisphosphate receptor that shows both steady-state and quantal patterns of Ca2+ release from intracellular stores
- De Paor, Timmons, 1986
- A feedback oscillator model for circulatory autoregulation
- De Vries, Sherman, 2000
- Channel Sharing in Pancreatic Beta-Cells Revisited: Enhancement of Emergent Bursting by Noise
- De Vries, Sherman, 2001
- From Spikers to Bursters Via Coupling: Help from Heterogeneity
- De Young, Keizer, 1992
- A single-pool inositol 1,4,5-triphosphate-receptor-based model for agonist-stimulated oscillations in Ca 2+ concentration
- Decker, Heijman, Silva, Hund, Rudy, 2009
- Properties and ionic mechanisms of action potential adaptation, restitution, and accommodation in canine epicardium
- Demir, Clark, Giles, 1999
- Parasympathetic modulation of sinoatrial node pacemaker activity in rabbit heart: a unifying model
- Demir, Clark, Giles, Murphey, 1994
- A Mathematical Model of a Rabbit Sinoatrial Node Cell
- Demiray, 1981
- Large deformation analysis of some soft biological tissues
- Dempsher, Gann, Phair, 1984
- A mechanistic model of ACTH-stimulated cortisol secretion
- Dependence of the period on the rate of protein degradation in minimal models for circadian oscillations
- DiFrancesco, Noble, 1985
- A Model of Cardiac Electrical Activity Incorporating Ionic Pumps and Concentration Changes
- Dijkstra, Neal, Beever, France, 1992
- Simulation of nutrient digestion, absorption and outflow in the rumen: model description
- Dixit, Perelson, 2004
- Complex patterns of viral load decay under antiretroviral therapy: influence of pharmacokinetics and intracellular delay
- Dokos, Celler, Lovell, 1996
- Ion currents underlying sinoatrial node pacemaker activity: a new single cell mathematical model
- Dougherty, Wright, Yew, 2005
- Computational model of the cAMP-mediated sensory response and calcium-dependent adaptation in vertebrate olfactory receptor neurons
- Drouhard, Roberge, 1987
- Revised formulation of the Hodgkin-Huxley representation of the sodium current in cardiac cells
- Dumaine, Towbin, Brugada, Vatta, Nesterenko, Nesterenko, Brugada, Brugada, Antzelevitch, 1999
- Ionic mechanisms responsible for the electrocardiographic phenotype of the Brugada Syndrome are temperature dependent
- Dupont, Berridge, Goldbetter, 1991
- Signal-induced Ca2+ oscillations: Properties of a model based on (Ca2+)-induced Ca2+ release
- Dupont, Goldbeter, 1992
- Protein phosphorylation driven by intracellular calcium oscillations: A kinetic analysis
- Dynamic Model of Amino Acid and Carbohydrate Metabolism in Primary Human Liver Cells
- Earm, Noble, 1990
- A Model of the Single Atrial Cell: Relation between Calcium Current and Calcium Release
- Ebihara, Johnson, 1980
- Fast sodium current in cardiac muscle: A quantitative description
- Edwards, 2010
- Edwards, 2010
- Model of the renal medullary pericyte and its effects on the descending vasa recta.
- Egli, Bertram, Sellix, Freeman, 2004
- Rhythmic secretion of prolactin in rats: action of oxytocin coordinated by vasoactive intestinal polypeptide of suprachiasmatic nucleus origin
- ElectrEcoBlu Systems Model
- Elowitz, Leibler, 2000
- A Synthetic Oscillatory Network of Transciptional Regulators
- Enciso, Sontag, 2004
- On the stability of a model of testosterone dynamics
- Endresen, 1996
- Chaos in Weakly-coupled Pacemaker Cells
- Eskandari, Wright, Loo 2005
- Eskandari, Wright, Loo 2005
- Eskandari, Wright, Loo,
- Kinetics of the Reverse Mode of the Na+/Glucose Cotransporter
- Espinosa, 1998
- L'Echange Na+/Ca2+ dans l'Hypertrophie Ventriculaire D'Altitude chez le Rat: Etude Electrophysiologique et Utilisation du Modele "Oxsoft Heart"
- Evans, Errington, Shelly, Feeney, Chapman, Godfrey, Smith, Chappell, 2004
- A mathematical model for the in vitro kinetics of the anti-cancer agent topotecan
- Faber, Rudy, 2000
- Action potential and contractility changes in [Na(+)](i) overloaded cardiac myocytes: a simulation study.
- Faber, Rudy, 2000 and Tong, Ghouri, Taggart, 2014
- (1) Action potential and contractility changes in [Na(+)](i) overloaded cardiac myocytes: a simulation study. (2) Computational modeling of inhibition of voltage-gated Ca channels: identification of different effects on uterine and cardiac action potentials.
- Fall, Keizer, 2001
- Mitochondrial Modulation of Intracellular Ca2+ Signalling
- Fallon, Lauffenburger, 2000
- Computational Model for Effects of Ligand/Receptor Binding Properties on Interleukin-2 Trafficking Dynamics and T Cell Proliferation Response
- Farhy, Bowers, Veldhuis, 2007
- Model-projected mechanistic bases for sex differences in growth hormone regulation in humans.
- Farhy, Bowers, Veldhuis, 2007
- Model-projected mechanistic bases for sex differences in growth hormone regulation in humans.
- Faville, Pullan, Sanders, Koh, Lloyd, Smith, 2009
- Biophysically based mathematical modeling of interstitial cells of Cajal slow wave activity generated from a discrete unitary potential basis
- Faville, Pullan, Sanders, Smith, 2008
- A Biophysically Based Mathematical Model of Unitary Potential Activity in Interstitial Cells of Cajal
- Fenton, Karma, 1998
- Vortex dynamics in three-dimensional continuous myocardium with fiber rotation: Filament instability and fibrillation
- Fink, Noble, Virag, Varro, Giles, 2008
- Contributions of HERG K+ current to repolarization of the human ventricular action potential
- Fink, Slepchenko, Loew, 1999
- Determination of time-dependent inositol-1,4,5-triphosphate concentrations during calcium release in a smooth muscle cell
- Fink, Slepchenko, Moraru, Watras, Schaff, Loew, 2000
- An image-based model of calcium waves in differentiated neuroblastoma cells
- Fitzhugh, 1961
- Impulses and Physiological States in Theoretical Models of Nerve Membrane
- Flynn, Green, Pedley, Boxer, Dearling, Watson, Boden, Begent, 2002
- A Model-Based Approach for the Optimization of Radioimmunotherapy through Antibody Design and Radionuclide Selection
- Fohlmeister, Miller, 1997
- Impulse Encoding Mechanisms of Ganglion Cells in the Tiger Salamander Retina
- Fox, McHarg, Gilmour, 2002
- Ionic mechanism of electrical alternans
- Fridlyand, Tamarina, Philipson, 2003
- Modeling of Ca2+ flux in pancreatic beta-cells: role of the plasma membrane and intracellular stores
- Fujita, Toyoshima, Uda, Ozaki, Kubota, Kuroda, 2010
- Decoupling of receptor and downstream signals in the Akt pathway by its low-pass filter characteristics
- Gall, Susa, 1999
- Effect of Na/Ca Exchange on Plateau Fraction and [Ca]i in Models for Bursting in Pancreatic Beta-Cells
- Gardner, Dolnik, Collins, 1998
- A theory for controlling cell cycle dynamics using a reversibly binding inhibitor
- Garmendia_Torres, Goldbeter, Jacquet,
- Nucleocytoplasmic oscillations of the yeast transcription factor Msn2: evidence for periodic PKA activation
- Garny, Kohl, Hunter, Boyett, Noble, 2003
- One-dimensional Rabbit Sinoatrial Node Models: Benefits and Limitations
- Gasser, Ogden, Holzapfel, 2006
- Hyperelastic modelling of arterial layers with distributed collagen fibre orientations
- Gattoni 2016
- Gerard, Goldbeter, 2010
- Temporal self-organization of the cyclin/Cdk network driving the mammalian cell cycle
- Gilbert, Heiner, Rosser, Fulton, Gu, Trybilo, 2007
- A Case Study in Model-driven Synthetic Biology
- Goforth, Bertram, Khan, Zhang, Sherman, Satin, 2002
- Calcium-activated K+ Channels of Mouse Beta Cells are Controlled by Both Store and Cytoplasmic Ca2+: Experimental and Theoretical Studies
- Goldbeter,
- A model for the dynamics of human weight cycling
- Goldbeter, 1991
- A minimal cascade model for the mitotic oscillator involving cyclin and cdc2 kinase
- Goldbeter, 1995
- A model for circadian oscillations in the Drosophila period protein (PER)
- Goldbeter, Dupont, Berridge, 1990
- Minimal model for signal-induced Ca2+ oscillations and for their frequency encoding through protein phosphorylation
- Goldbeter, Gonze, Pourquie, 2007
- Sharp Developmental Thresholds Defined Through Bistability By Antagonistic Gradients of Retinoic Acid and FGF Signaling
- Goldbeter, Pourquie, 2008
- Modeling the segmentation clock as a network of coupled oscillations in the Notch, Wnt and FGF signaling pathways
- Gonzalez-Heydrich, Steingard, Kohane, 1994
- A computer simulation of the hypothalamic-pituitary-adrenal axis
- Goodwin, 1965
- Oscillatory behavior in enzymatic control processes
- Grandi, Pasqualini, Bers, 2009
- A novel computational model of the human ventricular action potential and Ca transient
- Grange, Holford, Guentert, 2001
- A pharmacokinetic model to predict the PK interaction of L-dopa and benserazide in rats
- Greenstein, Wu, Po, Tomaselli, Winslow, 2000
- Role of the Calcium-Independent Transient Outward Current Ito1 in Shaping Action Potential Morphology and Duration
- Grossman, Feinberg, Kuznetsov, Dimitrov, Paul, 1998
- HIV infection: how effective is drug combination treatment?
- Guccione, Mcculloch, Waldman, 1991
- Gupta, Aslakson, Gurbaxani, Vernon, 2007
- Inclusion of the glucocorticoid receptor in a hypothalamic pituitary adrenal axis model reveals bistability
- Guyton, Aldosterone, 2008
- Description of Guyton aldosterone module
- Guyton, Angiotensin, 2008
- Description of Guyton angiotensin module
- Guyton, Antidiuretic Hormone, 2008
- Description of Guyton antidiuretic hormone module
- Guyton, Atrial Natriuretic Peptide, 2008
- Description of Guyton atrial natriuretic peptide module
- Guyton, Autonomics, 2008
- Description of Guyton autonomics module
- Guyton, Capillary Dynamics, 2008
- Description of Guyton capillary dynamics module
- Guyton, Cardiovascular, Circulation, 2008
- Description of Guyton 1992 Full Cardiovascular Circulation Model
- Guyton, Circulatory Dynamics, 2008
- Description of Guyton circulatory dynamics module
- Guyton, Electrolytes, 2008
- Description of Guyton electrolytes module
- Guyton, Heart Hypertrophy or Deterioration, 2008
- Description of Guyton heart hypertrophy or deterioration module
- Guyton, Heart Rate and Stroke Volume, 2008
- Description of Guyton heart rate and stroke volume module
- Guyton, Kidney, 2008
- Description of Guyton kidney module
- Guyton, Muscle Blood Flow Control, 2008
- Description of Guyton muscle blood flow control module
- Guyton, Muscle Oxygen Delivery, 2008
- Description of Guyton muscle oxygen delivery module
- Guyton, Non-Muscle Blood Flow, 2008
- Description of Guyton non-muscle local blood flow control module
- Guyton, Non-Muscle Oxygen Delivery, 2008
- Description of Guyton non-muscle oxygen delivery module
- Guyton, Pulmonary Fluid Dynamics, 2008
- Description of Guyton pulmonary fluid dynamics module
- Guyton, Pulmonary Oxygen Uptake, 2008
- Description of Guyton pulmonary oxygen uptake module
- Guyton, Red Cells and Viscosity, 2008
- Description of Guyton red cells and viscosity module
- Guyton, Stress Relaxation, 2008
- Description of Guyton stress relaxation module
- Guyton, Thirst, Drinking and Salt Appetite, 2008
- Description of guyton thirst, drinking and salt appetite module
- Guyton, Volume Receptors, 2008
- Description of Guyton volume receptors module
- H+-ATPase (V-type) Model
- Hai, Murphy, 1988
- Cross-bridge phosphorylation and regulation of latch state in smooth muscle
- Halloy, Bernard, Loussouarn, Goldbeter, 2002
- The Follicular Automaton Model: Effect of Stochasticity and of Synchronization of Hair Cycles
- Hatakeyama, Shirouzu, Yokoyama, Konagaya, Kimura, Naka, Kawasaki, Yumoto, Ichikawa, Kim, Saito, Saeki, 2003
- A computational model on the modulation of mitogen-activated protein kinase (MAPK) and Akt pathways in heregulin-induced ErbB signalling
- Hatzimanikatis, Lee, Bailey, 1999
- A mathematical description of regulation of the G1-S transition of the mammalian cell cycle
- Haugh, 2004
- Mathematical model of human growth hormone (hGH)-stimulated cell proliferation explains the efficacy of hGH variants as receptor agonists or antagonists
- Heinze, Keener, Midgley, 1998
- A mathematical model of luteinizing hormone release from ovine pituitary cells in perifusion
- Heldt, Shim, Kamm, Mark, 2002
- Computational modeling of cardiovascular response to orthostatic stress
- Herz, Bonhoeffer, Anderson, May, Nowak, 1996
- Viral Dynamics in vivo: Limitations on estimates of intracellular delay and virus decay
- Heyd, Drew, 2003
- A mathematical model for elongation of a peptide chain
- Hilgemann, Noble, 1987
- Excitation-contraction coupling and extracellular calcium transients in rabbit atrium: reconstruction of basic cellular mechanisms
- Hinch, Greenstein, Tanskanen, Xu, Winslow, 2004
- A Simplified Local Control Model of Calcium-Induced Calcium Release in Cardiac Ventricular Myocytes
- Hodgkin, Huxley, 1952
- A quantitative description of membrane current and its application to conductance and excitation in nerve
- Hoefnagel, Starrenburg, Martens, Hugenholtz, Kleerebezem, Van Swam, Bongers, Westerhoff, Snoep, 2002
- Metabolic engineering of lactic acid bacteria, the combined approach: kinetic modelling, metabolic control and experimental analysis
- Holmes, 2006
- Teaching from classic papers: Hill's model of muscle contraction
- Hornberg, Binder, Bruggeman, Schoeberl, Heinrich, Westerhoff, 2005
- Control of MAPK signalling: from complexity to what really matters
- Houart, Dupont, Albert, 1999
- Bursting, Chaos and birhythmicity Originating from Self-modulation of the Inositol 1,4,5-triphosphate Signal in a Model for Intracellular Ca2+ Oscillations
- Huang, Ferrell, 1996
- Ultrasensitivity in the mitogen-activated protein kinase cascade
- Hund, Rudy, 2004
- Rate dependence and regulation of action potential and calcium transient in a canine cardiac ventricular cell model
- Hunter, McCulloch, ter Keurs, 1998
- Modelling the mechanical properties of cardiac muscle
- Hunter, McNaughton, Noble, 1975
- Analytical models of propagation in excitable cells
- Hunter, Smaill, Hunter, 1995
- A pole-zero constitutive law for myocardium
- Hynne, Dano, Sorensen, 2001
- Full-scale model of glycolysis in Saccharomyces cerevisiae
- Iancu, Jones, Harvey, 2007
- Compartmentation of cAMP signaling in cardiac myocytes: a computational study
- Iber, Maini, 2002
- A Mathematical Model for Germinal Centre Kinetics and Affinity Maturation
- Improvement of metabolic performance of primary hepatocytes in hyperoxic cultures by vitamin C in a novel small-scale bioreactor
- Inada, Hancox, Zhang, Boyett, 2009
- One-dimensional mathematical model of the atrioventricular node including atrio-nodal, nodal, and nodal-his cells
- International SI Units, 2006
- International SI Units, 2006
- Iribe, Kohl, Noble, 2006
- Modulatory effect of calmodulin-dependent kinase II (CaMKII) on sarcoplasmic reticulum Ca2+ handling and interval-force relations: a modelling study.
- Irvine, Jafri, Winslow, 1999
- Cardiac sodium channel Markov model with temperature dependence and recovery from inactivation
- Itskov, Ehret, Mavrilas, 2006
- A Polyconvex Anisotropic Strain-Energy Function for Soft Collagenous Tissues
- Iyer, Hajjar, Armoundas, 2007
- Mechanisms of Abnormal Calcium Homeostasis in Mutations Responsible for Catecholaminergic Polymorphic Ventricular Tachycardia
- Iyer, Mazhari, Winslow, 2004
- A computational model of the human left-ventricular epicardial myocyte
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- Mathematical modeling and analysis of force induced bone growth
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- Theory of Time-Resolved Somatic Complementation and Its Use to Explore the Sporulation Control Network in Physarum polycephalum
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- Hepatitis C Viral Dynamics in Vivo and the Antiviral Efficacy of Interferon-alpha Therapy
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- The Role of Sodium-Calcium Exchange During the Cardiac Action Potential
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- Mathematical model of the fission yeast cell cycle with checkpoint controls at the G1/S, G2/M and metaphase/anaphase transitions
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- Mathematical model of the cell division cycle of fission yeast
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- Modeling the control of DNA replication in fission yeast
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- On the encoding and decoding of calcium signals in hepatocytes
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- Finite element modelling of contracting skeletal muscle
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- PKPD model of interleukin-21 effects on thermoregulation in monkeys--application and evaluation of stochastic differential equations
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- A Mathematical Model of the Electrophysiological Alterations in Rat Ventricular Myocytes in Type-I Diabetes
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- A Model of Cardiac Muscle Mechanics and Energetics
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- Electrogenic Properties of the Cloned Na+/Glucose Cotransporter: II. A Transport Model under Nonrapid Equilibrium Conditions
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- The functional role of cardiac T-tubules explored in a model of rat ventricular myocytes
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- Dynamics of HIV infection of CD4+ T cells
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- Plant, 1981
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- Response to continuous and pulsatile PTH dosing: a mathematical model for parathyroid hormone receptor kinetics
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- Mathematical model for the androgenic regulation of the prostate in intact and castrated adult male rats.
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- Simulation Study of Cellular Electrical Properties in Heart Failure
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- An in silico model of the ubiquitin-proteasome system that incorporates normal homeostasis and age-related decline
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- Dynamics of the Cell Cycle: Checkpoints, Sizers, and Timers
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- Mathematical analysis of canine atrial action potentials: rate, regional factors, and electrical remodeling
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- A minimal mathematical model of calcium homeostasis
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- Different Myofilament Nearest-Neighbor Interactions Have Distinctive Effects on Contractile Behavior
- Reconstruction of the action potential of ventricular myocardial fibres
- Reconstruction of the action potential of ventricular myocardial fibres
- Reconstruction of the action potential of ventricular myocardial fibres, with modifications to demonstrate uncertainty.
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- A mathematical model of the methionine cycle
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- Model of Calcium Oscillations Due to Negative Feedback in Olfactory Cilia
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- Renal SGLT1 model
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- Fighting a virus with a virus: a dynamic model for HIV-1 therapy
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- Modeling Activation and Desensitisation of G-Protein Coupled Receptors Provides Insight into Ligand Efficacy
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- Rice, Wang, Bers, de Tombe, 2008
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- Comparison of putative cooperative mechanisms in cardiac muscle: length dependence and dynamic responses (model 1)
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- Modeling of Protein Interactions Involved in Cardiac Tension Development
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- Mechanistic Model of Myocardial Energy Metabolism Under Normal and Ischemic Conditions
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- Cell-Level Pharmacokinetic Model of Granulocyte Colony-Stimulating Factor: Implications for Ligand Lifetime and Potency in Vivo
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- Calmodulin Mediates Differential Sensitivity of CAMKII and Calcineurin to Local Ca2+ in Cardiac Myocytes
- Saucerman, Brunton, Michailova, McCulloch, 2003
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- Mechanistic systems models of cell signaling networks: a case study of myocyte adrenergic regulation
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- A model for AIDS pathogenesis
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- A model of gonadotropin regulation during the menstrual cycle in women: qualitative features
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- Myocardial Material Parameter Estimation - A Comparative Study for Simple Shear
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- Mechanism of the Frank-Starling law-- A simulation study with a novel cardiac muscle contraction model that includes titin and tropomyosin
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- Computational Modeling of the Dynamics of the MAP Kinase Cascade Activated by Surface and Internalized EGF Receptors.
- Schuster, Beny, Meister, 2003
- Modelling the electrophysiological endothelial cell response to bradykinin
- Sedaghat, Sherman, Quon, 2002
- A mathematical model of metabolic insulin signaling pathways
- Seemann, Sachse, Weib, Dossel, 2003
- Quantitative Reconstruction of Cardiac Electromechanics in Human Myocardium: Regional Heterogeneity
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- A Mathematical Treatment of Integrated Ca Dynamics within the Ventricular Myocyte
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- Modeling the Cardiovascular System
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- Electrophysiological effects of acute myocardial ischemia: a theoretical study of altered cell excitability and action potential duration
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- Shi, Lawford, Hose, 2010
- Numerical Modeling of Hemodynamics with Pulsatile Impeller Pump Support
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- Model of Intracellular Calcium Cycling in Ventricular Myocytes
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- A mathematical model of fatigue in skeletal muscle force contraction
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- CRH-induced Electrical Activity and Calcium Signalling in Pituitary Corticotrophs
- Shorten, Wall, 2000
- A Hodgkin-Huxley Model Exhibiting Bursting Oscillations
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- Nonlinearities make a difference: comparison of two common Hill-type models with real muscle
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- Termination of Cardiac Ca2+ Sparks: An Investigative Mathematical Model of Calcium-Induced Calcium Release
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- A model of excitation and adaptation in bacterial chemotaxis
- Spronck, 2012
- Sriram, Bernot, Kepes, 2007
- A minimal mathematical model combining several regulatory cycles from the budding yeast cell cycle
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- Epidermal Growth Factor Binding and Trafficking Dynamics in Fibroblasts: Relationship to Cell Proliferation
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- Local Control Models of Cardiac Excitation-Contraction Coupling A Possible Role for Allosteric Interactions between Ryanodine Receptors
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- Analysis of a Model for the Pathogenesis of AIDS
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- A Mathematical Study of Volume Shifts and Ionic Concentration Changes during Ischemia and Hypoxia
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- Two Components of the Delayed Rectifier K+ Current in Ventricular Myocytes of the Guinea Pig Type
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