- Author:
- David Nickerson <nickerso@users.sourceforge.net>
- Date:
- 2012-10-05 15:20:03+13:00
- Desc:
- updating documentation to better reflect the VPH-MIP slides and mention how to reproduce the simulation results; adding plot of gating variables added to the SED-ML
- Permanent Source URI:
- http://models.cellml.org/w/andre/VPH-MIP/rawfile/58e44de10bed7fbc87fd1d437f3001c7b653a738/components/INa-gating-rates.xml
<?xml version="1.0" encoding="iso-8859-1"?>
<model xmlns="http://www.cellml.org/cellml/1.1#" xmlns:cellml="http://www.cellml.org/cellml/1.1#" xmlns:xlink="http://www.w3.org/1999/xlink" name="INa_gating_rates">
<import xlink:href="units.xml">
<units name="ms" units_ref="ms"/>
<units name="mV" units_ref="mV"/>
<units name="per_ms" units_ref="per_ms"/>
<units name="per_ms_mV" units_ref="per_ms_mV"/>
</import>
<component name="alpha_m">
<variable name="alpha" public_interface="out" private_interface="out" units="per_ms"/>
<variable name="V" public_interface="in" private_interface="out" units="mV"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply id="alpha_m_calculation"><eq/>
<ci>alpha</ci>
<apply><divide/>
<apply><times/>
<cn cellml:units="per_ms_mV">0.1</cn>
<apply><plus/>
<ci>V</ci>
<cn cellml:units="mV">25.0</cn>
</apply>
</apply>
<apply><minus/>
<apply><exp/>
<apply><divide/>
<apply><plus/>
<ci>V</ci>
<cn cellml:units="mV">25.0</cn>
</apply>
<cn cellml:units="mV">10.0</cn>
</apply>
</apply>
<cn cellml:units="dimensionless">1.0</cn>
</apply>
</apply>
</apply>
</math>
</component>
<component name="beta_m">
<variable name="beta" public_interface="out" private_interface="out" units="per_ms"/>
<variable name="V" public_interface="in" private_interface="out" units="mV"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply id="beta_m_calculation"><eq/>
<ci>beta</ci>
<apply><times/>
<cn cellml:units="per_ms">4.0</cn>
<apply><exp/>
<apply><divide/>
<ci>V</ci>
<cn cellml:units="mV">18.0</cn>
</apply>
</apply>
</apply>
</apply>
</math>
</component>
<component name="alpha_h">
<variable name="alpha" public_interface="out" private_interface="out" units="per_ms"/>
<variable name="V" public_interface="in" private_interface="out" units="mV"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply id="alpha_h_calculation"><eq/>
<ci>alpha</ci>
<apply><times/>
<cn cellml:units="per_ms">0.07</cn>
<apply><exp/>
<apply><divide/>
<ci>V</ci>
<cn cellml:units="mV">20.0</cn>
</apply>
</apply>
</apply>
</apply>
</math>
</component>
<component name="beta_h">
<variable name="beta" public_interface="out" private_interface="out" units="per_ms"/>
<variable name="V" public_interface="in" private_interface="out" units="mV"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply id="beta_h_calculation"><eq/>
<ci>beta</ci>
<apply><divide/>
<cn cellml:units="per_ms">1.0</cn>
<apply><plus/>
<apply><exp/>
<apply><divide/>
<apply><plus/>
<ci>V</ci>
<cn cellml:units="mV">30.0</cn>
</apply>
<cn cellml:units="mV">10.0</cn>
</apply>
</apply>
<cn cellml:units="dimensionless">1.0</cn>
</apply>
</apply>
</apply>
</math>
</component>
</model>
