Location: Noble 1962 model for Physiome article @ 0a252e033bdf / potassium_channel_model.xml

Author:
David Nickerson <nickerso@users.sourceforge.net>
Date:
2017-07-06 22:57:44+12:00
Desc:
exposing all model variables via the experiment model to allow SED-ML to address interesting things in the model
Permanent Source URI:
http://models.cellml.org/workspace/49e/rawfile/0a252e033bdf5e65d5a6490c9d3ade9035fef04e/potassium_channel_model.xml

<?xml version='1.0'?>
<model name="potassium_channel_model" xmlns="http://www.cellml.org/cellml/1.1#" xmlns:cellml="http://www.cellml.org/cellml/1.1#" xmlns:xlink="http://www.w3.org/1999/xlink">
    <component name="potassium_channel">
        <variable name="i_K" private_interface="out" public_interface="out" units="uA_per_mm2"/>
        <variable name="g_K1" private_interface="out" public_interface="out" units="mS_per_mm2"/>
        <variable name="g_K2" private_interface="out" public_interface="out" units="mS_per_mm2"/>
        <variable name="g_K_add" private_interface="out" public_interface="in" units="mS_per_mm2"/>
        <variable name="time" private_interface="out" public_interface="in" units="ms"/>
        <variable name="V" private_interface="out" public_interface="in" units="mV"/>
        <variable name="n" private_interface="out" public_interface="in" units="dimensionless"/>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply id="i_K_calculation">
                <eq/>
                <ci>i_K</ci>
                <apply>
                    <times/>
                    <apply>
                        <plus/>
                        <ci>g_K1</ci>
                        <ci>g_K2</ci>
                        <ci>g_K_add</ci>
                    </apply>
                    <apply>
                        <plus/>
                        <ci>V</ci>
                        <cn cellml:units="mV">100.0</cn>
                    </apply>
                </apply>
            </apply>
            <apply id="g_K1_calculation">
                <eq/>
                <ci>g_K1</ci>
                <apply>
                    <plus/>
                    <apply>
                        <times/>
                        <cn cellml:units="mS_per_mm2" type="e-notation">1.2<sep/>-2</cn>
                        <apply>
                            <exp/>
                            <apply>
                                <divide/>
                                <apply>
                                    <minus/>
                                    <apply>
                                        <minus/>
                                        <ci>V</ci>
                                    </apply>
                                    <cn cellml:units="mV">90.0</cn>
                                </apply>
                                <cn cellml:units="mV">50.0</cn>
                            </apply>
                        </apply>
                    </apply>
                    <apply>
                        <times/>
                        <cn cellml:units="mS_per_mm2" type="e-notation">0.015<sep/>-2</cn>
                        <apply>
                            <exp/>
                            <apply>
                                <divide/>
                                <apply>
                                    <plus/>
                                    <ci>V</ci>
                                    <cn cellml:units="mV">90.0</cn>
                                </apply>
                                <cn cellml:units="mV">60.0</cn>
                            </apply>
                        </apply>
                    </apply>
                </apply>
            </apply>
            <apply id="g_K2_calculation">
                <eq/>
                <ci>g_K2</ci>
                <apply>
                    <times/>
                    <cn cellml:units="mS_per_mm2" type="e-notation">1.2<sep/>-2</cn>
                    <apply>
                        <power/>
                        <ci>n</ci>
                        <cn cellml:units="dimensionless">4.0</cn>
                    </apply>
                </apply>
            </apply>
        </math>
    </component>
    <import xlink:href="units_model.xml">
        <units name="mm" units_ref="mm"/>
        <units name="ng" units_ref="ng"/>
        <units name="ms" units_ref="ms"/>
        <units name="uA" units_ref="uA"/>
        <units name="K" units_ref="K"/>
        <units name="nmol" units_ref="nmol"/>
        <units name="mmsq" units_ref="mmsq"/>
        <units name="mmcu" units_ref="mmcu"/>
        <units name="mssq" units_ref="mssq"/>
        <units name="mscu" units_ref="mscu"/>
        <units name="mV" units_ref="mV"/>
        <units name="mVsq" units_ref="mVsq"/>
        <units name="mV_per_ms" units_ref="mV_per_ms"/>
        <units name="mS" units_ref="mS"/>
        <units name="mS_per_mmsq" units_ref="mS_per_mmsq"/>
        <units name="mS_per_mm" units_ref="mS_per_mm"/>
        <units name="uA_per_mmsq" units_ref="uA_per_mmsq"/>
        <units name="uA_per_mmcu" units_ref="uA_per_mmcu"/>
        <units name="nC" units_ref="nC"/>
        <units name="uF" units_ref="uF"/>
        <units name="uF_per_mmsq" units_ref="uF_per_mmsq"/>
        <units name="mM" units_ref="mM"/>
        <units name="mM_per_ms" units_ref="mM_per_ms"/>
        <units name="nN" units_ref="nN"/>
        <units name="mPa" units_ref="mPa"/>
        <units name="pJ" units_ref="pJ"/>
        <units name="nW" units_ref="nW"/>
        <units name="per_ms" units_ref="per_ms"/>
        <units name="per_mm" units_ref="per_mm"/>
        <units name="per_mV" units_ref="per_mV"/>
        <units name="per_mV_per_ms" units_ref="per_mV_per_ms"/>
        <units name="per_mM_per_ms" units_ref="per_mM_per_ms"/>
        <units name="uA_per_mmsq_per_mM" units_ref="uA_per_mmsq_per_mM"/>
        <units name="mm_per_ms" units_ref="mm_per_ms"/>
        <units name="gas_constant" units_ref="gas_constant"/>
        <units name="faradays_constant" units_ref="faradays_constant"/>
        <units name="pA_per_pF" units_ref="pA_per_pF"/>
        <units name="nS_per_pF" units_ref="nS_per_pF"/>
        <units name="uF_per_cmsq" units_ref="uF_per_cmsq"/>
        <units name="um" units_ref="um"/>
        <units name="umsq" units_ref="umsq"/>
        <units name="umcu" units_ref="umcu"/>
        <units name="cmcu_per_uF_per_s" units_ref="cmcu_per_uF_per_s"/>
        <units name="mM_per_s" units_ref="mM_per_s"/>
        <units name="per_mV_ms" units_ref="per_mV_ms"/>
        <units name="mS_per_mm2" units_ref="mS_per_mm2"/>
        <units name="uF_per_mm2" units_ref="uF_per_mm2"/>
        <units name="uA_per_mm2" units_ref="uA_per_mm2"/>
    </import>
</model>