def import using "kraetler_functions.cellml" for comp f_NE_B1AR_module using comp f_module; enddef; def import using "kraetler_functions.cellml" for comp f_B1ARPA_B1AR_module using comp f_module; enddef; def import using "kraetler_functions.cellml" for comp f_B1ARPG_B1AR_module using comp f_module; enddef; def import using "kraetler_functions.cellml" for comp f_B1AR_GRK_module using comp f_module; enddef; def import using "kraetler_functions.cellml" for comp f_B1AR_Gsabg_module using comp f_module; enddef; def import using "kraetler_functions.cellml" for comp f_GRK_B1ARPG_module using comp f_module; enddef; def import using "kraetler_functions.cellml" for comp f_Gsabg_Gsbg_module using comp f_module; enddef; def import using "kraetler_functions.cellml" for comp f_Gsabg_Gsa_module using comp f_module; enddef; def import using "kraetler_functions.cellml" for comp f_Gsa_AC_module using comp f_module; enddef; def import using "kraetler_functions.cellml" for comp f_AC_cAMP_module using comp f_module; enddef; def import using "kraetler_functions.cellml" for comp f_FSK_AC_module using comp f_module; enddef; def import using "kraetler_functions.cellml" for comp f_IBMX_PDE_module using comp f_module; enddef; def import using "kraetler_functions.cellml" for comp f_PDE_cAMP_module using comp f_module; enddef; def import using "kraetler_functions.cellml" for comp f_cAMP_PKA_module using comp f_module; enddef; def import using "kraetler_functions.cellml" for comp f_PKA_PKAR_module using comp f_module; enddef; def import using "kraetler_functions.cellml" for comp f_PKA_PKAC_module using comp f_module; enddef; def import using "kraetler_functions.cellml" for comp f_PKI_PKAC_module using comp f_module; enddef; def import using "kraetler_functions.cellml" for comp f_PP2A_TnI_module using comp f_module; enddef; def import using "kraetler_functions.cellml" for comp f_PP2A_Inhib1_module using comp f_module; enddef; def import using "kraetler_functions.cellml" for comp f_PP2A_ICa_module using comp f_module; enddef; def import using "kraetler_functions.cellml" for comp f_PP2A_RyR_module using comp f_module; enddef; def import using "kraetler_functions.cellml" for comp f_PKAC_B1ARPA_module using comp f_module; enddef; def import using "kraetler_functions.cellml" for comp f_PKAC_PLB_module using comp f_module; enddef; def import using "kraetler_functions.cellml" for comp f_PKAC_IKs_module using comp f_module; enddef; def import using "kraetler_functions.cellml" for comp f_PKAC_ICa_module using comp f_module; enddef; def import using "kraetler_functions.cellml" for comp f_PKAC_RyR_module using comp f_module; enddef; def import using "kraetler_functions.cellml" for comp f_PKAC_TnI_module using comp f_module; enddef; def import using "kraetler_functions.cellml" for comp f_PKAC_Inhib1_module using comp f_module; enddef; def import using "kraetler_functions.cellml" for comp f_Inhib1_PP1_module using comp f_module; enddef; def import using "kraetler_functions.cellml" for comp f_PP1_RyR_module using comp f_module; enddef; def import using "kraetler_functions.cellml" for comp f_PP1_ICa_module using comp f_module; enddef; def import using "kraetler_functions.cellml" for comp f_PP1_IKs_module using comp f_module; enddef; def import using "kraetler_functions.cellml" for comp f_PP1_PLB_module using comp f_module; enddef; var NE: mM {init: 0, pub: out}; var B1AR: mM {init: 0, pub: out}; var GRK: mM {init: 0, pub: out}; var B1ARPG: mM {init: 0, pub: out}; var B1ARPA: mM {init: 0, pub: out}; var Gsabg: mM {init: 0, pub: out}; var Gsa: mM {init: 0, pub: out}; var Gsbg: mM {init: 0, pub: out}; var FSK: mM {init: 0, pub: out}; var AC: mM {init: 0, pub: out}; var IBMX: mM {init: 0, pub: out}; var PDE: mM {init: 0, pub: out}; var cAMP: mM {init: 0, pub: out}; var PKA: mM {init: 0, pub: out}; var PKAR: mM {init: 0, pub: out}; var PKI: mM {init: 0, pub: out}; var PKAC: mM {init: 0, pub: out}; var PP2A: mM {init: 0, pub: out}; var IKs: mM {init: 0, pub: out}; var ICa: mM {init: 0, pub: out}; var RyR: mM {init: 0, pub: out}; var Inhib1: mM {init: 0, pub: out}; var TnI: mM {init: 0, pub: out}; var PLB: mM {init: 0, pub: out}; var PP1: mM {init: 0, pub: out}; var tau_NE: second {init: 0, pub: out}; var tau_B1AR: second {init: 0, pub: out}; var tau_GRK: second {init: 0, pub: out}; var tau_B1ARPG: second {init: 0, pub: out}; var tau_B1ARPA: second {init: 0, pub: out}; var tau_Gsabg: second {init: 0, pub: out}; var tau_Gsa: second {init: 0, pub: out}; var tau_Gsbg: second {init: 0, pub: out}; var tau_FSK: second {init: 0, pub: out}; var tau_AC: second {init: 0, pub: out}; var tau_IBMX: second {init: 0, pub: out}; var tau_PDE: second {init: 0, pub: out}; var tau_cAMP: second {init: 0, pub: out}; var tau_PKA: second {init: 0, pub: out}; var tau_PKAR: second {init: 0, pub: out}; var tau_PKI: second {init: 0, pub: out}; var tau_PKAC: second {init: 0, pub: out}; var tau_PP2A: second {init: 0, pub: out}; var tau_IKs: second {init: 0, pub: out}; var tau_ICa: second {init: 0, pub: out}; var tau_RyR: second {init: 0, pub: out}; var tau_Inhib1: second {init: 0, pub: out}; var tau_TnI: second {init: 0, pub: out}; var tau_PLB: second {init: 0, pub: out}; var tau_PP1: second {init: 0, pub: out}; var EC50_NE_B1AR: dimensionless {init: 0.5, pub: out}; var EC50_B1ARPA_B1AR: dimensionless {init: 0.5, pub: out}; var EC50_B1ARPG_B1AR: dimensionless {init: 0.5, pub: out}; var EC50_B1AR_GRK: dimensionless {init: 0.5, pub: out}; var EC50_B1AR_Gsabg: dimensionless {init: 0.5, pub: out}; var EC50_GRK_B1ARPG: dimensionless {init: 0.5, pub: out}; var EC50_Gsabg_Gsbg: dimensionless {init: 0.5, pub: out}; var EC50_Gsabg_Gsa: dimensionless {init: 0.5, pub: out}; var EC50_Gsa_AC: dimensionless {init: 0.5, pub: out}; var EC50_AC_cAMP: dimensionless {init: 0.5, pub: out}; var EC50_FSK_AC: dimensionless {init: 0.5, pub: out}; var EC50_IBMX_PDE: dimensionless {init: 0.5, pub: out}; var EC50_PDE_cAMP: dimensionless {init: 0.5, pub: out}; var EC50_cAMP_PKA: dimensionless {init: 0.5, pub: out}; var EC50_PKA_PKAR: dimensionless {init: 0.5, pub: out}; var EC50_PKA_PKAC: dimensionless {init: 0.5, pub: out}; var EC50_PKI_PKAC: dimensionless {init: 0.5, pub: out}; var EC50_PP2A_TnI: dimensionless {init: 0.5, pub: out}; var EC50_PP2A_Inhib1: dimensionless {init: 0.5, pub: out}; var EC50_PP2A_ICa: dimensionless {init: 0.5, pub: out}; var EC50_PP2A_RyR: dimensionless {init: 0.5, pub: out}; var EC50_PKAC_B1ARPA: dimensionless {init: 0.5, pub: out}; var EC50_PKAC_PLB: dimensionless {init: 0.5, pub: out}; var EC50_PKAC_IKs: dimensionless {init: 0.5, pub: out}; var EC50_PKAC_ICa: dimensionless {init: 0.5, pub: out}; var EC50_PKAC_RyR: dimensionless {init: 0.5, pub: out}; var EC50_PKAC_TnI: dimensionless {init: 0.5, pub: out}; var EC50_PKAC_Inhib1: dimensionless {init: 0.5, pub: out}; var EC50_Inhib1_PP1: dimensionless {init: 0.5, pub: out}; var EC50_PP1_RyR: dimensionless {init: 0.5, pub: out}; var EC50_PP1_ICa: dimensionless {init: 0.5, pub: out}; var EC50_PP1_IKs: dimensionless {init: 0.5, pub: out}; var EC50_PP1_PLB: dimensionless {init: 0.5, pub: out}; var W_NE_B1AR: dimensionless {init: 1, pub: out}; var W_B1ARPA_B1AR: dimensionless {init: 1, pub: out}; var W_B1ARPG_B1AR: dimensionless {init: 1, pub: out}; var W_B1AR_GRK: dimensionless {init: 1, pub: out}; var W_B1AR_Gsabg: dimensionless {init: 1, pub: out}; var W_GRK_B1ARPG: dimensionless {init: 1, pub: out}; var W_Gsabg_Gsbg: dimensionless {init: 1, pub: out}; var W_Gsabg_Gsa: dimensionless {init: 1, pub: out}; var W_Gsa_AC: dimensionless {init: 1, pub: out}; var W_AC_cAMP: dimensionless {init: 1, pub: out}; var W_FSK_AC: dimensionless {init: 1, pub: out}; var W_IBMX_PDE: dimensionless {init: 1, pub: out}; var W_PDE_cAMP: dimensionless {init: 1, pub: out}; var W_cAMP_PKA: dimensionless {init: 1, pub: out}; var W_PKA_PKAR: dimensionless {init: 1, pub: out}; var W_PKA_PKAC: dimensionless {init: 1, pub: out}; var W_PKI_PKAC: dimensionless {init: 1, pub: out}; var W_PP2A_TnI: dimensionless {init: 1, pub: out}; var W_PP2A_Inhib1: dimensionless {init: 1, pub: out}; var W_PP2A_ICa: dimensionless {init: 1, pub: out}; var W_PP2A_RyR: dimensionless {init: 1, pub: out}; var W_PKAC_B1ARPA: dimensionless {init: 1, pub: out}; var W_PKAC_PLB: dimensionless {init: 1, pub: out}; var W_PKAC_IKs: dimensionless {init: 1, pub: out}; var W_PKAC_ICa: dimensionless {init: 1, pub: out}; var W_PKAC_RyR: dimensionless {init: 1, pub: out}; var W_PKAC_TnI: dimensionless {init: 1, pub: out}; var W_PKAC_Inhib1: dimensionless {init: 1, pub: out}; var W_Inhib1_PP1: dimensionless {init: 1, pub: out}; var W_PP1_RyR: dimensionless {init: 1, pub: out}; var W_PP1_ICa: dimensionless {init: 1, pub: out}; var W_PP1_IKs: dimensionless {init: 1, pub: out}; var W_PP1_PLB: dimensionless {init: 1, pub: out}; var f_act_NE_B1AR: dimensionless {pub: in}; var f_act_B1AR_GRK: dimensionless {pub: in}; var f_act_B1AR_Gsabg: dimensionless {pub: in}; var f_act_GRK_B1ARPG: dimensionless {pub: in}; var f_act_Gsabg_Gsbg: dimensionless {pub: in}; var f_act_Gsabg_Gsa: dimensionless {pub: in}; var f_act_Gsa_AC: dimensionless {pub: in}; var f_act_AC_cAMP: dimensionless {pub: in}; var f_act_FSK_AC: dimensionless {pub: in}; var f_act_cAMP_PKA: dimensionless {pub: in}; var f_act_PKA_PKAR: dimensionless {pub: in}; var f_act_PKA_PKAC: dimensionless {pub: in}; var f_act_PKAC_B1ARPA: dimensionless {pub: in}; var f_act_PKAC_PLB: dimensionless {pub: in}; var f_act_PKAC_IKs: dimensionless {pub: in}; var f_act_PKAC_ICa: dimensionless {pub: in}; var f_act_PKAC_RyR: dimensionless {pub: in}; var f_act_PKAC_TnI: dimensionless {pub: in}; var f_act_PKAC_Inhib1: dimensionless {pub: in}; var f_inh_B1ARPA_B1AR: dimensionless {pub: in}; var f_inh_B1ARPG_B1AR: dimensionless {pub: in}; var f_inh_IBMX_PDE: dimensionless {pub: in}; var f_inh_PDE_cAMP: dimensionless {pub: in}; var f_inh_PKI_PKAC: dimensionless {pub: in}; var f_inh_PP2A_TnI: dimensionless {pub: in}; var f_inh_PP2A_Inhib1: dimensionless {pub: in}; var f_inh_PP2A_ICa: dimensionless {pub: in}; var f_inh_PP2A_RyR: dimensionless {pub: in}; var f_inh_Inhib1_PP1: dimensionless {pub: in}; var f_inh_PP1_RyR: dimensionless {pub: in}; var f_inh_PP1_ICa: dimensionless {pub: in}; var f_inh_PP1_IKs: dimensionless {pub: in}; var f_inh_PP1_PLB: dimensionless {pub: in}; ode(NE, time) = (ppp)/tau_NE; ode(B1AR, time) = (ppp)/tau_B1AR; ode(GRK, time) = (ppp)/tau_GRK; ode(B1ARPG, time) = (ppp)/tau_B1ARPG; ode(B1ARPA, time) = (ppp)/tau_B1ARPA; ode(Gsabg, time) = (ppp)/tau_Gsabg; ode(Gsa, time) = (ppp)/tau_Gsa; ode(Gsbg, time) = (ppp)/tau_Gsbg; ode(FSK, time) = (ppp)/tau_FSK; ode(AC, time) = (ppp)/tau_AC; ode(IBMX, time) = (ppp)/tau_IBMX; ode(PDE, time) = (ppp)/tau_PDE; ode(cAMP, time) = (ppp)/tau_cAMP; ode(PKA, time) = (ppp)/tau_PKA; ode(PKAR, time) = (ppp)/tau_PKAR; ode(PKI, time) = (ppp)/tau_PKI; ode(PKAC, time) = (ppp)/tau_PKAC; ode(PP2A, time) = (ppp)/tau_PP2A; ode(IKs, time) = (ppp)/tau_IKs; ode(ICa, time) = (ppp)/tau_ICa; ode(RyR, time) = (ppp)/tau_RyR; ode(Inhib1, time) = (ppp)/tau_Inhib1; ode(TnI, time) = (ppp)/tau_TnI; ode(PLB, time) = (ppp)/tau_PLB; ode(PP1, time) = (ppp)/tau_PP1; def map between env and f_NE_B1AR_module for vars W_NE_B1AR and W; vars n and n; vars EC50_NE_B1AR and EC50; vars NE and X; vars f_act_NE_B1AR and f_act; enddef; def map between env and f_B1AR_GRK_module for vars W_B1AR_GRK and W; vars n and n; vars EC50_B1AR_GRK and EC50; vars B1AR and X; vars f_act_B1AR_GRK and f_act; enddef; def map between env and f_B1AR_Gsabg_module for vars W_B1AR_Gsabg and W; vars n and n; vars EC50_B1AR_Gsabg and EC50; vars B1AR and X; vars f_act_B1AR_Gsabg and f_act; enddef; def map between env and f_GRK_B1ARPG_module for vars W_GRK_B1ARPG and W; vars n and n; vars EC50_GRK_B1ARPG and EC50; vars GRK and X; vars f_act_GRK_B1ARPG and f_act; enddef; def map between env and f_Gsabg_Gsbg_module for vars W_Gsabg_Gsbg and W; vars n and n; vars EC50_Gsabg_Gsbg and EC50; vars Gsabg and X; vars f_act_Gsabg_Gsbg and f_act; enddef; def map between env and f_Gsabg_Gsa_module for vars W_Gsabg_Gsa and W; vars n and n; vars EC50_Gsabg_Gsa and EC50; vars Gsabg and X; vars f_act_Gsabg_Gsa and f_act; enddef; def map between env and f_Gsa_AC_module for vars W_Gsa_AC and W; vars n and n; vars EC50_Gsa_AC and EC50; vars Gsa and X; vars f_act_Gsa_AC and f_act; enddef; def map between env and f_AC_cAMP_module for vars W_AC_cAMP and W; vars n and n; vars EC50_AC_cAMP and EC50; vars AC and X; vars f_act_AC_cAMP and f_act; enddef; def map between env and f_FSK_AC_module for vars W_FSK_AC and W; vars n and n; vars EC50_FSK_AC and EC50; vars FSK and X; vars f_act_FSK_AC and f_act; enddef; def map between env and f_cAMP_PKA_module for vars W_cAMP_PKA and W; vars n and n; vars EC50_cAMP_PKA and EC50; vars cAMP and X; vars f_act_cAMP_PKA and f_act; enddef; def map between env and f_PKA_PKAR_module for vars W_PKA_PKAR and W; vars n and n; vars EC50_PKA_PKAR and EC50; vars PKA and X; vars f_act_PKA_PKAR and f_act; enddef; def map between env and f_PKA_PKAC_module for vars W_PKA_PKAC and W; vars n and n; vars EC50_PKA_PKAC and EC50; vars PKA and X; vars f_act_PKA_PKAC and f_act; enddef; def map between env and f_PKAC_B1ARPA_module for vars W_PKAC_B1ARPA and W; vars n and n; vars EC50_PKAC_B1ARPA and EC50; vars PKAC and X; vars f_act_PKAC_B1ARPA and f_act; enddef; def map between env and f_PKAC_PLB_module for vars W_PKAC_PLB and W; vars n and n; vars EC50_PKAC_PLB and EC50; vars PKAC and X; vars f_act_PKAC_PLB and f_act; enddef; def map between env and f_PKAC_IKs_module for vars W_PKAC_IKs and W; vars n and n; vars EC50_PKAC_IKs and EC50; vars PKAC and X; vars f_act_PKAC_IKs and f_act; enddef; def map between env and f_PKAC_ICa_module for vars W_PKAC_ICa and W; vars n and n; vars EC50_PKAC_ICa and EC50; vars PKAC and X; vars f_act_PKAC_ICa and f_act; enddef; def map between env and f_PKAC_RyR_module for vars W_PKAC_RyR and W; vars n and n; vars EC50_PKAC_RyR and EC50; vars PKAC and X; vars f_act_PKAC_RyR and f_act; enddef; def map between env and f_PKAC_TnI_module for vars W_PKAC_TnI and W; vars n and n; vars EC50_PKAC_TnI and EC50; vars PKAC and X; vars f_act_PKAC_TnI and f_act; enddef; def map between env and f_PKAC_Inhib1_module for vars W_PKAC_Inhib1 and W; vars n and n; vars EC50_PKAC_Inhib1 and EC50; vars PKAC and X; vars f_act_PKAC_Inhib1 and f_act; enddef; def map between env and f_B1ARPA_B1AR_module for vars W_B1ARPA_B1AR and W; vars n and n; vars EC50_B1ARPA_B1AR and EC50; vars B1ARPA and X; vars f_inh_B1ARPA_B1AR and f_inhib; enddef; def map between env and f_B1ARPG_B1AR_module for vars W_B1ARPG_B1AR and W; vars n and n; vars EC50_B1ARPG_B1AR and EC50; vars B1ARPG and X; vars f_inh_B1ARPG_B1AR and f_inhib; enddef; def map between env and f_IBMX_PDE_module for vars W_IBMX_PDE and W; vars n and n; vars EC50_IBMX_PDE and EC50; vars IBMX and X; vars f_inh_IBMX_PDE and f_inhib; enddef; def map between env and f_PDE_cAMP_module for vars W_PDE_cAMP and W; vars n and n; vars EC50_PDE_cAMP and EC50; vars PDE and X; vars f_inh_PDE_cAMP and f_inhib; enddef; def map between env and f_PKI_PKAC_module for vars W_PKI_PKAC and W; vars n and n; vars EC50_PKI_PKAC and EC50; vars PKI and X; vars f_inh_PKI_PKAC and f_inhib; enddef; def map between env and f_PP2A_TnI_module for vars W_PP2A_TnI and W; vars n and n; vars EC50_PP2A_TnI and EC50; vars PP2A and X; vars f_inh_PP2A_TnI and f_inhib; enddef; def map between env and f_PP2A_Inhib1_module for vars W_PP2A_Inhib1 and W; vars n and n; vars EC50_PP2A_Inhib1 and EC50; vars PP2A and X; vars f_inh_PP2A_Inhib1 and f_inhib; enddef; def map between env and f_PP2A_ICa_module for vars W_PP2A_ICa and W; vars n and n; vars EC50_PP2A_ICa and EC50; vars PP2A and X; vars f_inh_PP2A_ICa and f_inhib; enddef; def map between env and f_PP2A_RyR_module for vars W_PP2A_RyR and W; vars n and n; vars EC50_PP2A_RyR and EC50; vars PP2A and X; vars f_inh_PP2A_RyR and f_inhib; enddef; def map between env and f_Inhib1_PP1_module for vars W_Inhib1_PP1 and W; vars n and n; vars EC50_Inhib1_PP1 and EC50; vars Inhib1 and X; vars f_inh_Inhib1_PP1 and f_inhib; enddef; def map between env and f_PP1_RyR_module for vars W_PP1_RyR and W; vars n and n; vars EC50_PP1_RyR and EC50; vars PP1 and X; vars f_inh_PP1_RyR and f_inhib; enddef; def map between env and f_PP1_ICa_module for vars W_PP1_ICa and W; vars n and n; vars EC50_PP1_ICa and EC50; vars PP1 and X; vars f_inh_PP1_ICa and f_inhib; enddef; def map between env and f_PP1_IKs_module for vars W_PP1_IKs and W; vars n and n; vars EC50_PP1_IKs and EC50; vars PP1 and X; vars f_inh_PP1_IKs and f_inhib; enddef; def map between env and f_PP1_PLB_module for vars W_PP1_PLB and W; vars n and n; vars EC50_PP1_PLB and EC50; vars PP1 and X; vars f_inh_PP1_PLB and f_inhib; enddef;