Location: Cooling, Hunter, Crampin, 2009 @ 42fe9ea9efed / calcium_DualProtocol.cellml
- Author:
- Hanne <Hanne@hanne-nielsens-macbook.local>
- Date:
- 2010-08-09 14:56:34+12:00
- Desc:
- Added images in ai and svg format
- Permanent Source URI:
- http://models.cellml.org/workspace/cooling_hunter_crampin_2009/rawfile/42fe9ea9efedaea902239e6a309185af0e6ccc95/calcium_DualProtocol.cellml
<?xml version="1.0" encoding="iso-8859-1"?>
<model
name="calcium"
cmeta:id="calcium"
xmlns="http://www.cellml.org/cellml/1.1#"
xmlns:cellml="http://www.cellml.org/cellml/1.1#"
xmlns:cmeta="http://www.cellml.org/metadata/1.0#">
<rdf:RDF
xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
xmlns:cmeta="http://www.cellml.org/metadata/1.0#"
xmlns:bqs="http://www.cellml.org/bqs/1.0#"
xmlns:dc="http://purl.org/dc/elements/1.1/"
xmlns:dcterms="http://purl.org/dc/terms/"
xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#">
<rdf:Description rdf:about="#calcium">
<dc:creator rdf:parseType="Resource">
<vCard:N rdf:parseType="Resource">
<vCard:Family>Cooling</vCard:Family>
<vCard:Given>Michael</vCard:Given>
</vCard:N>
<vCard:EMAIL rdf:parseType="Resource">
<rdf:value>m.cooling@auckland.ac.nz</rdf:value>
<rdf:type rdf:resource="http://imc.org/vCard/3.0#internet" />
</vCard:EMAIL>
</dc:creator>
<dc:title>Cooling's calcium module for the Dual calcium protocol</dc:title>
</rdf:Description>
</rdf:RDF>
<!--
*******************************************************
*** U N I T S ***
*******************************************************
-->
<units name="s">
<unit units="second"/>
</units>
<units xmlns="http://www.cellml.org/cellml/1.0#" name="nM">
<unit units="mole" prefix="nano"/>
<unit units="liter" exponent="-1"/>
</units>
<units xmlns="http://www.cellml.org/cellml/1.0#" name="per_s">
<unit units="s" exponent="-1"/>
</units>
<units xmlns="http://www.cellml.org/cellml/1.0#" name="nM_per_s">
<unit units="nM"/>
<unit units="s" exponent="-1"/>
</units>
<units xmlns="http://www.cellml.org/cellml/1.0#" name="ms">
<unit units="s" exponent="-3"/>
</units>
<units xmlns="http://www.cellml.org/cellml/1.0#" name="nM_per_ms">
<unit units="nM"/>
<unit units="ms" exponent="-1"/>
</units>
<!--
*********************************************************
*** C O M P O N E N T S ***
*********************************************************
-->
<component name="calcium">
<variable name="t" units="s" public_interface="in"/>
<variable name="Ca" units="nM" public_interface="out"/>
<variable name="ms_in_pulse" units="ms"/>
<variable name="period" units="s" initial_value="1.02"/>
<variable name="baseline" units="nM"/>
<variable name="stimGradient" units="nM_per_ms"/>
<variable name="CaBeat" units="nM"/>
<variable name="CaSigTrans" units="nM" initial_value="0"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>ms_in_pulse</ci>
<apply>
<times/>
<cn cellml:units="dimensionless">1000</cn>
<apply>
<minus/>
<ci>t</ci>
<apply>
<times/>
<apply>
<floor/>
<apply>
<divide/>
<ci>t</ci>
<ci>period</ci>
</apply>
</apply>
<ci>period</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>baseline</ci>
<piecewise>
<piece>
<cn cellml:units="nM">93</cn>
<apply>
<geq/>
<ci>period</ci>
<cn cellml:units="s">0.12</cn>
</apply>
</piece>
<otherwise>
<apply>
<plus/>
<cn cellml:units="nM">1121</cn>
<apply>
<times/>
<apply>
<minus/>
<apply>
<times/>
<ci>period</ci>
<cn cellml:units="dimensionless">1000</cn>
</apply>
<cn cellml:units="ms">16</cn>
</apply>
<apply>
<minus/>
<cn cellml:units="nM_per_ms">9.8846</cn>
</apply>
</apply>
</apply>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>stimGradient</ci>
<apply>
<divide/>
<apply>
<minus/>
<cn cellml:units="nM">1121</cn>
<ci>baseline</ci>
</apply>
<cn cellml:units="ms">16</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>CaBeat</ci>
<piecewise>
<piece>
<apply>
<plus/>
<apply>
<times/>
<ci>ms_in_pulse</ci>
<ci>stimGradient</ci>
</apply>
<ci>baseline</ci>
</apply>
<apply>
<leq/>
<ci>ms_in_pulse</ci>
<cn cellml:units="ms">16</cn>
</apply>
</piece>
<piece>
<apply>
<plus/>
<apply>
<times/>
<apply>
<minus/>
<ci>ms_in_pulse</ci>
<cn cellml:units="ms">16</cn>
</apply>
<apply>
<minus/>
<cn cellml:units="nM_per_ms">9.8846</cn>
</apply>
</apply>
<cn cellml:units="nM">1121</cn>
</apply>
<apply>
<and/>
<apply>
<gt/>
<ci>ms_in_pulse</ci>
<cn cellml:units="ms">16</cn>
</apply>
<apply>
<leq/>
<ci>ms_in_pulse</ci>
<cn cellml:units="ms">120</cn>
</apply>
</apply>
</piece>
<otherwise>
<ci>baseline</ci>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>Ca</ci>
<apply>
<plus/>
<ci>CaBeat</ci>
<ci>CaSigTrans</ci>
</apply>
</apply>
</math>
</component>
</model>