May
Lloyd
Catherine
Re-added cmeta:id's for 4 major currents that had been deleted by COR
James
Richard
Lawson
Reuter
H
Beeler
G
2008-05-20T11:16:23+12:00
electrophysiology
electrophysiological
cardiac electrophysiology
ventricular myocyte
cardiac
keyword
This model has been curated and is known to run and reproduce the published results in PCEnv and COR. A PCEnv session file is also associated with this model.
Penny has curated this model from Flavio Fenton's model code. See http://thevirtualheart.org/ for Java applet rendering of model. Code available from Dr Fenton
Changed model cmeta:id from beeler_reuter_1977_version06 to beeler_reuter_1977
c.lloyd@auckland.ac.nz
0.1
10000
10000
Added an intial value for X1 to enable the model to run.
268(1)
210
177
Reconstruction of the action potential of ventricular myocardial fibres
2008-05-20T10:56:34+12:00
2008-05-08T03:15:26+12:00
Noble
Penny
James
Richard
Lawson
1977-06-00 00:00
Catherine Lloyd
Richard
James
Lawson
Updated cmeta:id's for reference by PCEnv sessions.
Added simulation metadata to allow simulation for 10,000 ms
James Lawson
Journal of Physiology
874889
In contrast to the earlier Purkinje fibre ionic current models of D. Noble (1962) and R.E. McAllister, D. Noble and R.W. Tsien (1975) (MNT model), the G.W. Beeler and H. Reuter 1977 model was developed to describe the mammalian ventricular action potential. Not all the ionic currents of the Purkinje fibre model are present in ventricular tissue; therefore, this model is simpler than the MNT model. The total ionic flux is divided into only four discrete, individual ionic currents. The main additional feature of the Beeler-Reuter ionic current model is a representation of the intracellular calcium ion concentration.
2008-05-08T00:00:00+00:00
2008-05-20T11:41:27+12:00
University of Auckland
Auckland Bioengineering Institute