/* There are a total of 2 entries in the algebraic variable array. There are a total of 3 entries in each of the rate and state variable arrays. There are a total of 13 entries in the constant variable array. */ /* * VOI is time in component environment (minute). * STATES[0] is C in component C (micromolar). * CONSTANTS[0] is v_i in component C (micromolar_per_minute). * CONSTANTS[1] is v_d in component C (micromolar_per_minute). * STATES[1] is X in component X (micromolar). * CONSTANTS[2] is K_d in component C (micromolar). * CONSTANTS[3] is k_d in component C (per_minute). * STATES[2] is M in component M (micromolar). * ALGEBRAIC[0] is V_1 in component V_1 (micromolar_per_minute). * CONSTANTS[4] is K_1 in component M (per_minute). * CONSTANTS[5] is V_2 in component M (per_minute). * CONSTANTS[6] is K_2 in component M (per_minute). * ALGEBRAIC[1] is V_3 in component V_3 (micromolar_per_minute). * CONSTANTS[7] is K_3 in component X (per_minute). * CONSTANTS[8] is V_4 in component X (per_minute). * CONSTANTS[9] is K_4 in component X (per_minute). * CONSTANTS[10] is K_c in component V_1 (micromolar). * CONSTANTS[11] is V_M1 in component V_1 (per_minute). * CONSTANTS[12] is V_M3 in component V_3 (per_minute). * RATES[0] is d/dt C in component C (micromolar). * RATES[2] is d/dt M in component M (micromolar). * RATES[1] is d/dt X in component X (micromolar). */ void initConsts(double* CONSTANTS, double* RATES, double *STATES) { STATES[0] = 0.1; CONSTANTS[0] = 0.05; CONSTANTS[1] = 0.25; STATES[1] = 0.1; CONSTANTS[2] = 0.02; CONSTANTS[3] = 0.01; STATES[2] = 0.1; CONSTANTS[4] = 0.01; CONSTANTS[5] = 1.5; CONSTANTS[6] = 0.01; CONSTANTS[7] = 0.01; CONSTANTS[8] = 0.5; CONSTANTS[9] = 0.01; CONSTANTS[10] = 0.5; CONSTANTS[11] = 3; CONSTANTS[12] = 1; } void computeRates(double VOI, double* CONSTANTS, double* RATES, double* STATES, double* ALGEBRAIC) { RATES[0] = (CONSTANTS[0] - CONSTANTS[1]*STATES[1]*(STATES[0]/(CONSTANTS[2]+STATES[0]))) - CONSTANTS[3]*STATES[0]; ALGEBRAIC[0] = (STATES[0]/(CONSTANTS[10]+STATES[0]))*CONSTANTS[11]; RATES[2] = ALGEBRAIC[0]*((1.00000 - STATES[2])/(CONSTANTS[4]+(1.00000 - STATES[2]))) - CONSTANTS[5]*(STATES[2]/(CONSTANTS[6]+STATES[2])); ALGEBRAIC[1] = STATES[2]*CONSTANTS[12]; RATES[1] = ALGEBRAIC[1]*((1.00000 - STATES[1])/(CONSTANTS[7]+(1.00000 - STATES[1]))) - CONSTANTS[8]*(STATES[1]/(CONSTANTS[9]+STATES[1])); } void computeVariables(double VOI, double* CONSTANTS, double* RATES, double* STATES, double* ALGEBRAIC) { ALGEBRAIC[0] = (STATES[0]/(CONSTANTS[10]+STATES[0]))*CONSTANTS[11]; ALGEBRAIC[1] = STATES[2]*CONSTANTS[12]; }