Generated Code

The following is python code generated by the CellML API from this CellML file. (Back to language selection)

The raw code is available.

# Size of variable arrays:
sizeAlgebraic = 1
sizeStates = 2
sizeConstants = 7
from math import *
from numpy import *

def createLegends():
    legend_states = [""] * sizeStates
    legend_rates = [""] * sizeStates
    legend_algebraic = [""] * sizeAlgebraic
    legend_voi = ""
    legend_constants = [""] * sizeConstants
    legend_voi = "time in component environment (hour)"
    legend_states[0] = "O2 in component O2 (CONCENTRATIONO2)"
    legend_constants[0] = "p1 in component O2 (CONFIRMp1)"
    legend_constants[1] = "F1 in component O2 (dimensionless)"
    legend_constants[2] = "p2 in component model_parameters (per_day)"
    legend_states[1] = "H2O2 in component H2O2 (CONCENTRATIONH2O2)"
    legend_constants[3] = "p3 in component H2O2 (per_day)"
    legend_constants[4] = "p4 in component H2O2 (per_day)"
    legend_algebraic[0] = "V in component V (CONFIRMV)"
    legend_constants[5] = "Vmax in component V (microgram_per_hour)"
    legend_constants[6] = "ki in component V (CONFIRMki)"
    legend_rates[0] = "d/dt O2 in component O2 (CONCENTRATIONO2)"
    legend_rates[1] = "d/dt H2O2 in component H2O2 (CONCENTRATIONH2O2)"
    return (legend_states, legend_algebraic, legend_voi, legend_constants)

def initConsts():
    constants = [0.0] * sizeConstants; states = [0.0] * sizeStates;
    states[0] = 0.00235897
    constants[0] = 0.0000143385
    constants[1] = 20
    constants[2] = 0.117425199
    states[1] = 0.000027947
    constants[3] = 2.552293418
    constants[4] = 8.379310334
    constants[5] = 10400000
    constants[6] = 0.000008982
    return (states, constants)

def computeRates(voi, states, constants):
    rates = [0.0] * sizeStates; algebraic = [0.0] * sizeAlgebraic
    rates[0] = constants[0]*constants[1]-constants[2]*states[0]
    rates[1] = (constants[2]*states[0]-constants[3]*states[1])-constants[4]*states[1]
    return(rates)

def computeAlgebraic(constants, states, voi):
    algebraic = array([[0.0] * len(voi)] * sizeAlgebraic)
    states = array(states)
    voi = array(voi)
    algebraic[0] = constants[5]*(constants[6]/(constants[6]+states[1]))
    return algebraic

def solve_model():
    """Solve model with ODE solver"""
    from scipy.integrate import ode
    # Initialise constants and state variables
    (init_states, constants) = initConsts()

    # Set timespan to solve over
    voi = linspace(0, 10, 500)

    # Construct ODE object to solve
    r = ode(computeRates)
    r.set_integrator('vode', method='bdf', atol=1e-06, rtol=1e-06, max_step=1)
    r.set_initial_value(init_states, voi[0])
    r.set_f_params(constants)

    # Solve model
    states = array([[0.0] * len(voi)] * sizeStates)
    states[:,0] = init_states
    for (i,t) in enumerate(voi[1:]):
        if r.successful():
            r.integrate(t)
            states[:,i+1] = r.y
        else:
            break

    # Compute algebraic variables
    algebraic = computeAlgebraic(constants, states, voi)
    return (voi, states, algebraic)

def plot_model(voi, states, algebraic):
    """Plot variables against variable of integration"""
    import pylab
    (legend_states, legend_algebraic, legend_voi, legend_constants) = createLegends()
    pylab.figure(1)
    pylab.plot(voi,vstack((states,algebraic)).T)
    pylab.xlabel(legend_voi)
    pylab.legend(legend_states + legend_algebraic, loc='best')
    pylab.show()

if __name__ == "__main__":
    (voi, states, algebraic) = solve_model()
    plot_model(voi, states, algebraic)