You are here: Home / Exposures / Mikane, Suga, Araki, Kohno, Nakayama, Suzuki, Shimuzi, Matsubara, Hirakawa, Takaki, 1997 / Mechanism of Constant Contractile Efficiency Under Cooling Intropy of Myocardium: Simulation

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Ca_release_rate = \{\begin{matrix} 0 if time > 0.1 \\ 20 Ca_tot_released (1 - (10 time)) otherwise \end{matrix} \frac{d}{d time} (Ca_t) = Ca_release_rate - (k_3 Ca_t) - dTnCa_t_dt \frac{d}{d time} (TnCa_t) = k_1 Ca_t (total_Tn - TnCa_t) - (k_2 TnCa_t) dTnCa_t_dt = k_1 Ca_t (total_Tn - TnCa_t) - (k_2 TnCa_t) \frac{d}{d time} (CB_on_t) = f TnCa_t (total_CB - CB_on_t) - (g CB_on_t) \frac{d}{d time} (Ca_released) = Ca_release_rate \frac{d}{d time} (Ca_sequestered) = k_3 Ca_t \frac{d}{d time} (cumCB_on_t) = f TnCa_t (total_CB - CB_on_t) \frac{d}{d time} (cumCB_off_t) = g CB_on_t

Source: Derived from workspace Mikane, Araki, Kohno, Nakayama, Suzuki, Shimuzi, Matsubara, Hirakawa, Takaki, Suga, 1997 at changeset 8e4de70f510e.

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Mechanism of Constant Contractile Efficiency Under Cooling Intropy of Myocardium: Simulation