P_O2
Open state 2
2007-05-18
Keizer and Levine's 1996 model of a gating scheme for ryanodine
receptors.
Cardiac Myocyte
The University of Auckland
The Bioengineering Institute
1996-12-01
Closed state 2
P_C2
71
3477
Ryanodine Receptor Adaptation and Ca2+-Induced Ca2+
Release-Dependent Ca2+ Oscillations
3487
8968617
c.lloyd@auckland.ac.nz
The University of Auckland, Bioengineering Institute
P_O1
Open state 1
Levine
Leslie
oscillator
ryanodine receptor
cardiac
Cardiac Myocyte
calcium dynamics
cicr
electrophysiology
ryanodine receptors
Joel
Keizer
Biophysical Journal
The new version of this model has been re-coded to remove the reaction element and replace it with a simple MathML description of the model reaction kinetics. This is thought to be truer to the original publication, and information regarding the enzyme kinetics etc will later be added to the metadata through use of an ontology.
The model runs in the PCEnv simulator but gives NaNs.
Catherine
May
Lloyd
Closed state 1
P_C1
Catherine
May
Lloyd
keyword
Cai
Intracellular calcium concentration in a closed cell
This is the CellML description of Keizer and Levine's 1996 model of a
gating scheme for ryanodine receptors in cardiac muscle.
Catherine Lloyd
2007-06-05T09:35:57+12:00
Open state on a slow time scale
P_O_slow