B
K
Skouibine
Bioengineering Institute, The University of Auckland
The closing rate of the x1 gate.
Updated metadata to conform to the 16/1/02 CellML Metadata 1.0
Specification.
The defibrillation Beeler-Reuter model
1999-07-01
The formula for the time independent outward potassium current of
the defibrillation Beeler-Reuter model is the same as for the
original Beeler-Reuter (1977) model.
A
Cuellar
Autumn
769
777
Anode/cathode make and break phenomena in a model of defibrillation
46
Trayanova
N
A
Autumn
A
Cuellar
excitation-contraction coupling
ventricular myocyte
cardiac
electrophysiology
Added more metadata.
The voltage-dependent inactivation gate for the slow inward current
- the f gate.
Moore
P
K
David
Nickerson
P
May
Lloyd
Catherine
Changed some units and added a stimulus current and touched up some
of the equations.
c.lloyd@auckland.ac.nz
The gating variable for the time-dependent outward potassium
current - the x1 gate.
2003-04-05
10396895
keyword
The voltage-dependent activation gate for the slow inward current -
the d gate.
The closing rate of the f gate.
Autumn
A.
Cuellar
The kinetics of the h gate.
The kinetics of the x1 gate.
2002-01-21
2003-04-01
The kinetics of the m gate.
The opening rate of the x1 gate.
The closing rate for the m gate.
Calculation of the fast sodium current.
The closing rate for the h gate.
A minor change is made to the intracellular calcium ion tracking to
limit the movement of calcium ions at large potentials. In addition
to these changes, a scale factor can be added to the time dependent
d and f gates to allow the scaling of the action potential duration.
This enables a better representation of an action potential from
ischemic tissue.
2001-12-28
This is the CellML description of the defibrillation Beeler-Reuter model. The original Beeler-Reuter model was modified by Drouhard and Roberge (1987) to improve the fast sodium kinetics. This model was then further modified by Skouibine et al (1999) to handle potentials outside the range of normal physiological activity, allowing the model to be used in defibrillation studies.
IEEE Trans Biomed Eng.
The kinetics of the f gate.
The opening rate for the h gate.
Calculation of the reversal potential for the slow inward current.
Changed the model name so the model loads in the database easier.
The closing rate of the d gate.
The time rate of change of intracellular calcium concentration.
The University of Auckland
The Bioengineering Research Group
While the governing equations for the time dependent outward
potassium current are unchanged, the gating variables (alpha_x1 and
beta_x1) are modified.
2003-07-28
The voltage-dependent activation gate for the fast sodium channel -
the m gate.
The main component for the model, defining the transmembrane
potential.
Catherine Lloyd
The opening rate of the f gate.
The main differential equation for the model, specifing membrane
potential as the summation of all ionic currents and an applied
stimulus current.
The fast sodium current, primarily responsible for the upstroke of
the action potential.
The kinetics of the d gate.
Calculation of the slow inward current.
The opening rate of the d gate.
The opening rate for the m gate.
defibrillation
The voltage-dependent inactivation gate for the fast sodium channel
- the h gate.