Generated Code
The following is c_ida code generated by the CellML API from this CellML file. (Back to language selection)
The raw code is available.
/* There are a total of 93 entries in the algebraic variable array. There are a total of 41 entries in each of the rate and state variable arrays. There are a total of 148 entries in the constant variable array. */ /* * VOI is time in component environment (second). * CONSTANTS[0] is R in component model_parameters (joule_per_kilomole_kelvin). * CONSTANTS[1] is T in component model_parameters (kelvin). * CONSTANTS[2] is F in component model_parameters (coulomb_per_mole). * CONSTANTS[3] is Na_e in component model_parameters (millimolar). * CONSTANTS[4] is Ca_e in component model_parameters (millimolar). * CONSTANTS[5] is K_e in component model_parameters (millimolar). * CONSTANTS[145] is Vt in component model_parameters (cm3). * CONSTANTS[112] is Vd in component model_parameters (cm3). * CONSTANTS[113] is Vmyo in component model_parameters (cm3). * CONSTANTS[116] is Sms in component model_parameters (cm2). * CONSTANTS[117] is Smt in component model_parameters (cm2). * CONSTANTS[147] is Cms in component model_parameters (microF). * CONSTANTS[146] is Cmt in component model_parameters (microF). * CONSTANTS[106] is Vc in component model_parameters (cm3). * CONSTANTS[114] is VSRup in component model_parameters (cm3). * CONSTANTS[115] is VSRrel in component model_parameters (cm3). * CONSTANTS[118] is pt in component model_parameters (dimensionless). * CONSTANTS[143] is Lt in component model_parameters (cm). * CONSTANTS[144] is Rst in component model_parameters (ohm). * CONSTANTS[6] is Rot in component model_parameters (ohm_per_cm2). * CONSTANTS[7] is radiust in component model_parameters (cm). * CONSTANTS[8] is ptcm in component model_parameters (per_cm). * CONSTANTS[9] is Smtot in component model_parameters (cm2). * ALGEBRAIC[0] is i_circ in component common_current (microA). * CONSTANTS[10] is R_st in component common_current (kilo_ohm). * STATES[0] is Vm_s in component membrane (millivolt). * STATES[1] is Vm_t in component membrane (millivolt). * ALGEBRAIC[1] is J_CaSRrel in component SR_Ca_release_channel (millimolar_per_second). * CONSTANTS[11] is kap in component SR_Ca_release_channel (per_millimolar4_per_second). * CONSTANTS[12] is kam in component SR_Ca_release_channel (per_second). * CONSTANTS[13] is kbp in component SR_Ca_release_channel (per_millimolar3_per_second). * CONSTANTS[14] is kbm in component SR_Ca_release_channel (per_second). * CONSTANTS[15] is kcp in component SR_Ca_release_channel (per_second). * CONSTANTS[16] is kcm in component SR_Ca_release_channel (per_second). * STATES[2] is F2 in component SR_Ca_release_channel (dimensionless). * STATES[3] is F3 in component SR_Ca_release_channel (dimensionless). * STATES[4] is F1 in component SR_Ca_release_channel (dimensionless). * STATES[5] is F4 in component SR_Ca_release_channel (dimensionless). * STATES[6] is Ca_ss in component ion_concentrations (millimolar). * STATES[7] is CaSRrel in component ion_concentrations (millimolar). * ALGEBRAIC[4] is J_CaSRup in component SERCA2a_pump (millimolar_per_second). * CONSTANTS[17] is K_fb in component SERCA2a_pump (millimolar). * CONSTANTS[18] is K_rb in component SERCA2a_pump (millimolar). * ALGEBRAIC[2] is fb in component SERCA2a_pump (dimensionless). * ALGEBRAIC[3] is rb in component SERCA2a_pump (dimensionless). * CONSTANTS[19] is Vmaxf in component SERCA2a_pump (millimolar_per_second). * CONSTANTS[20] is Vmaxr in component SERCA2a_pump (millimolar_per_second). * CONSTANTS[21] is K_SR in component SERCA2a_pump (dimensionless). * CONSTANTS[22] is N_fb in component SERCA2a_pump (dimensionless). * CONSTANTS[23] is N_rb in component SERCA2a_pump (dimensionless). * STATES[8] is Ca_i in component ion_concentrations (millimolar). * STATES[9] is CaSRup in component ion_concentrations (millimolar). * ALGEBRAIC[5] is J_tr in component intracellular_and_SR_Ca_fluxes (millimolar_per_second). * ALGEBRAIC[6] is J_xfer in component intracellular_and_SR_Ca_fluxes (millimolar_per_second). * ALGEBRAIC[9] is J_trpn in component intracellular_and_SR_Ca_fluxes (millimolar_per_second). * ALGEBRAIC[7] is J_BTRH in component intracellular_and_SR_Ca_fluxes (millimolar_per_second). * ALGEBRAIC[8] is J_BTRL in component intracellular_and_SR_Ca_fluxes (millimolar_per_second). * CONSTANTS[24] is BTRHmax in component intracellular_and_SR_Ca_fluxes (millimolar). * CONSTANTS[25] is BTRLmax in component intracellular_and_SR_Ca_fluxes (millimolar). * CONSTANTS[26] is tau_tr in component intracellular_and_SR_Ca_fluxes (second). * CONSTANTS[27] is tau_xfer in component intracellular_and_SR_Ca_fluxes (second). * STATES[10] is BTRH in component intracellular_and_SR_Ca_fluxes (millimolar). * STATES[11] is BTRL in component intracellular_and_SR_Ca_fluxes (millimolar). * CONSTANTS[28] is k_htrpn_plus in component intracellular_and_SR_Ca_fluxes (per_millimolar_per_second). * CONSTANTS[29] is k_htrpn_minus in component intracellular_and_SR_Ca_fluxes (per_second). * CONSTANTS[30] is k_ltrpn_plus in component intracellular_and_SR_Ca_fluxes (per_millimolar_per_second). * CONSTANTS[31] is k_ltrpn_minus in component intracellular_and_SR_Ca_fluxes (per_second). * STATES[12] is Na_i in component ion_concentrations (millimolar). * STATES[13] is K_i in component ion_concentrations (millimolar). * STATES[14] is Na_t in component ion_concentrations (millimolar). * STATES[15] is Ca_t in component ion_concentrations (millimolar). * STATES[16] is K_t in component ion_concentrations (millimolar). * ALGEBRAIC[10] is i_Kext in component ion_concentrations (microA). * CONSTANTS[32] is K_mCMDN in component ion_concentrations (millimolar). * CONSTANTS[33] is K_mCSQN in component ion_concentrations (millimolar). * CONSTANTS[34] is K_mEGTA in component ion_concentrations (millimolar). * CONSTANTS[35] is CMDN_tot in component ion_concentrations (millimolar). * CONSTANTS[36] is CSQN_tot in component ion_concentrations (millimolar). * CONSTANTS[37] is EGTA_tot in component ion_concentrations (millimolar). * CONSTANTS[38] is tau_d in component ion_concentrations (second). * CONSTANTS[39] is STIMULATION in component ion_concentrations (dimensionless). * CONSTANTS[40] is time0 in component ion_concentrations (second). * ALGEBRAIC[15] is i_Na_s in component sodium_current (microA). * ALGEBRAIC[27] is i_Ca_s in component calcium_current (microA). * ALGEBRAIC[46] is i_BNa_s in component background_currents (microA). * ALGEBRAIC[52] is i_NaCa_s in component Na_Ca_ion_exchanger_current (microA). * ALGEBRAIC[50] is i_NaK_s in component sodium_potassium_pump (microA). * ALGEBRAIC[41] is i_fNa_s in component hyperpolarisation_activated_current (microA). * ALGEBRAIC[42] is i_fK_s in component hyperpolarisation_activated_current (microA). * ALGEBRAIC[48] is i_BK_s in component background_currents (microA). * ALGEBRAIC[40] is i_K1_s in component inward_rectifier (microA). * ALGEBRAIC[29] is i_Kto_s in component Ca_independent_transient_outward_K_current (microA). * ALGEBRAIC[36] is i_Kss_s in component steady_state_outward_K_current (microA). * ALGEBRAIC[51] is i_CaP_s in component sarcolemmal_calcium_pump_current (microA). * ALGEBRAIC[47] is i_BCa_s in component background_currents (microA). * ALGEBRAIC[54] is i_Na_t in component sodium_current (microA). * ALGEBRAIC[66] is i_Ca_t in component calcium_current (microA). * ALGEBRAIC[85] is i_BNa_t in component background_currents (microA). * ALGEBRAIC[92] is i_NaCa_t in component Na_Ca_ion_exchanger_current (microA). * ALGEBRAIC[90] is i_NaK_t in component sodium_potassium_pump (microA). * ALGEBRAIC[80] is i_fNa_t in component hyperpolarisation_activated_current (microA). * ALGEBRAIC[81] is i_fK_t in component hyperpolarisation_activated_current (microA). * ALGEBRAIC[87] is i_BK_t in component background_currents (microA). * ALGEBRAIC[79] is i_K1_t in component inward_rectifier (microA). * ALGEBRAIC[68] is i_Kto_t in component Ca_independent_transient_outward_K_current (microA). * ALGEBRAIC[75] is i_Kss_t in component steady_state_outward_K_current (microA). * ALGEBRAIC[91] is i_CaP_t in component sarcolemmal_calcium_pump_current (microA). * ALGEBRAIC[86] is i_BCa_t in component background_currents (microA). * ALGEBRAIC[11] is Jte_Na in component t_tubular_ion_fluxes (millimolar_per_second). * ALGEBRAIC[12] is Jte_Ca in component t_tubular_ion_fluxes (millimolar_per_second). * ALGEBRAIC[13] is Jte_K in component t_tubular_ion_fluxes (millimolar_per_second). * CONSTANTS[41] is tau_Na in component t_tubular_ion_fluxes (second). * CONSTANTS[42] is tau_Ca in component t_tubular_ion_fluxes (second). * CONSTANTS[43] is tau_K in component t_tubular_ion_fluxes (second). * ALGEBRAIC[43] is i_f_s in component hyperpolarisation_activated_current (microA). * ALGEBRAIC[49] is i_B_s in component background_currents (microA). * ALGEBRAIC[14] is E_Na in component sodium_current (millivolt). * CONSTANTS[44] is g_Na in component sodium_current (milliS_per_cm2). * CONSTANTS[119] is g_Nas in component sodium_current (milliS). * CONSTANTS[45] is fNat in component sodium_current (dimensionless). * STATES[17] is m in component sodium_current_m_gate (dimensionless). * STATES[18] is h in component sodium_current_h_gate (dimensionless). * ALGEBRAIC[16] is alpha_m in component sodium_current_m_gate (per_second). * ALGEBRAIC[17] is beta_m in component sodium_current_m_gate (per_second). * ALGEBRAIC[18] is alpha_h in component sodium_current_h_gate (per_second). * ALGEBRAIC[19] is beta_h in component sodium_current_h_gate (per_second). * STATES[19] is Co in component calcium_current (dimensionless). * STATES[20] is C_cast in component calcium_current (dimensionless). * STATES[21] is C1 in component calcium_current (dimensionless). * STATES[22] is C2 in component calcium_current (dimensionless). * ALGEBRAIC[21] is tauCo in component calcium_current (second). * CONSTANTS[46] is tauC_cast in component calcium_current (second). * ALGEBRAIC[23] is tauC1 in component calcium_current (second). * ALGEBRAIC[25] is tauC2 in component calcium_current (second). * ALGEBRAIC[20] is Co_inf in component calcium_current (dimensionless). * ALGEBRAIC[26] is C_cast_inf in component calcium_current (dimensionless). * ALGEBRAIC[22] is C1_inf in component calcium_current (dimensionless). * ALGEBRAIC[24] is C2_inf in component calcium_current (dimensionless). * CONSTANTS[47] is g_Ca in component calcium_current (cm_per_second). * CONSTANTS[120] is g_Cas in component calcium_current (cm3_per_second). * CONSTANTS[48] is fCat in component calcium_current (dimensionless). * ALGEBRAIC[28] is E_K in component Ca_independent_transient_outward_K_current (millivolt). * CONSTANTS[49] is a in component Ca_independent_transient_outward_K_current (dimensionless). * CONSTANTS[50] is b in component Ca_independent_transient_outward_K_current (dimensionless). * CONSTANTS[51] is g_Kto in component Ca_independent_transient_outward_K_current (milliS_per_cm2). * CONSTANTS[121] is g_Ktos in component Ca_independent_transient_outward_K_current (milliS). * CONSTANTS[52] is fKtot in component Ca_independent_transient_outward_K_current (dimensionless). * STATES[23] is r in component Ca_independent_transient_outward_K_current_r_gate (dimensionless). * STATES[24] is s in component Ca_independent_transient_outward_K_current_s_gate (dimensionless). * STATES[25] is s_slow in component Ca_independent_transient_outward_K_current_s_slow_gate (dimensionless). * ALGEBRAIC[31] is tau_r in component Ca_independent_transient_outward_K_current_r_gate (second). * ALGEBRAIC[30] is r_max in component Ca_independent_transient_outward_K_current_r_gate (dimensionless). * ALGEBRAIC[33] is tau_s in component Ca_independent_transient_outward_K_current_s_gate (second). * ALGEBRAIC[32] is s_max in component Ca_independent_transient_outward_K_current_s_gate (dimensionless). * ALGEBRAIC[35] is tau_s_slow in component Ca_independent_transient_outward_K_current_s_slow_gate (second). * ALGEBRAIC[34] is s_slow_max in component Ca_independent_transient_outward_K_current_s_slow_gate (dimensionless). * CONSTANTS[53] is g_Kss in component steady_state_outward_K_current (milliS_per_cm2). * CONSTANTS[122] is g_Ksss in component steady_state_outward_K_current (milliS). * CONSTANTS[54] is fKsst in component steady_state_outward_K_current (dimensionless). * STATES[26] is r_ss in component steady_state_outward_K_current_r_ss_gate (dimensionless). * STATES[27] is s_ss in component steady_state_outward_K_current_s_ss_gate (dimensionless). * ALGEBRAIC[38] is tau_r_ss in component steady_state_outward_K_current_r_ss_gate (second). * ALGEBRAIC[37] is r_ss_max in component steady_state_outward_K_current_r_ss_gate (dimensionless). * CONSTANTS[107] is tau_s_ss in component steady_state_outward_K_current_s_ss_gate (second). * ALGEBRAIC[39] is s_ss_max in component steady_state_outward_K_current_s_ss_gate (dimensionless). * CONSTANTS[55] is g_K1 in component inward_rectifier (milliS_per_cm2). * CONSTANTS[123] is g_K1s in component inward_rectifier (milliS). * CONSTANTS[56] is fK1t in component inward_rectifier (dimensionless). * CONSTANTS[57] is g_f in component hyperpolarisation_activated_current (milliS_per_cm2). * CONSTANTS[124] is g_fs in component hyperpolarisation_activated_current (milliS). * CONSTANTS[58] is fft in component hyperpolarisation_activated_current (dimensionless). * CONSTANTS[59] is f_Na in component hyperpolarisation_activated_current (dimensionless). * CONSTANTS[108] is f_K in component hyperpolarisation_activated_current (dimensionless). * STATES[28] is y in component hyperpolarisation_activated_current_y_gate (dimensionless). * ALGEBRAIC[45] is tau_y in component hyperpolarisation_activated_current_y_gate (second). * ALGEBRAIC[44] is y_infinity in component hyperpolarisation_activated_current_y_gate (dimensionless). * CONSTANTS[60] is g_B_Ca in component background_currents (milliS_per_cm2). * CONSTANTS[61] is g_B_Na in component background_currents (milliS_per_cm2). * CONSTANTS[62] is g_B_K in component background_currents (milliS_per_cm2). * CONSTANTS[125] is g_B_Cas in component background_currents (milliS). * CONSTANTS[126] is g_B_Nas in component background_currents (milliS). * CONSTANTS[127] is g_B_Ks in component background_currents (milliS). * CONSTANTS[63] is fCabt in component background_currents (dimensionless). * CONSTANTS[64] is fNabt in component background_currents (dimensionless). * CONSTANTS[65] is fKbt in component background_currents (dimensionless). * CONSTANTS[66] is E_Ca in component background_currents (millivolt). * CONSTANTS[67] is i_NaK_max in component sodium_potassium_pump (microA_per_cm2). * CONSTANTS[128] is i_NaK_max_s in component sodium_potassium_pump (microA). * CONSTANTS[68] is fNaKt in component sodium_potassium_pump (dimensionless). * CONSTANTS[69] is K_m_K in component sodium_potassium_pump (millimolar). * CONSTANTS[70] is K_m_Na in component sodium_potassium_pump (millimolar). * CONSTANTS[109] is sigma in component sodium_potassium_pump (dimensionless). * CONSTANTS[71] is i_CaP_max in component sarcolemmal_calcium_pump_current (microA_per_cm2). * CONSTANTS[129] is i_CaP_max_s in component sarcolemmal_calcium_pump_current (microA). * CONSTANTS[72] is fCaPt in component sarcolemmal_calcium_pump_current (dimensionless). * CONSTANTS[73] is i_NaCa_max in component Na_Ca_ion_exchanger_current (microA_per_cm2). * CONSTANTS[130] is i_NaCa_max_s in component Na_Ca_ion_exchanger_current (microA). * CONSTANTS[74] is fNaCat in component Na_Ca_ion_exchanger_current (dimensionless). * ALGEBRAIC[82] is i_f_t in component hyperpolarisation_activated_current (microA). * ALGEBRAIC[88] is i_B_t in component background_currents (microA). * ALGEBRAIC[53] is E_Na in component sodium_current (millivolt). * CONSTANTS[75] is g_Na in component sodium_current (milliS_per_cm2). * CONSTANTS[131] is g_Nat in component sodium_current (milliS). * CONSTANTS[76] is fNat in component sodium_current (dimensionless). * STATES[29] is m in component sodium_current_m_gate (dimensionless). * STATES[30] is h in component sodium_current_h_gate (dimensionless). * ALGEBRAIC[55] is alpha_m in component sodium_current_m_gate (per_second). * ALGEBRAIC[56] is beta_m in component sodium_current_m_gate (per_second). * ALGEBRAIC[57] is alpha_h in component sodium_current_h_gate (per_second). * ALGEBRAIC[58] is beta_h in component sodium_current_h_gate (per_second). * STATES[31] is Co in component calcium_current (dimensionless). * STATES[32] is C_cast in component calcium_current (dimensionless). * STATES[33] is C1 in component calcium_current (dimensionless). * STATES[34] is C2 in component calcium_current (dimensionless). * ALGEBRAIC[60] is tauCo in component calcium_current (second). * CONSTANTS[77] is tauC_cast in component calcium_current (second). * ALGEBRAIC[62] is tauC1 in component calcium_current (second). * ALGEBRAIC[64] is tauC2 in component calcium_current (second). * ALGEBRAIC[59] is Co_inf in component calcium_current (dimensionless). * ALGEBRAIC[65] is C_cast_inf in component calcium_current (dimensionless). * ALGEBRAIC[61] is C1_inf in component calcium_current (dimensionless). * ALGEBRAIC[63] is C2_inf in component calcium_current (dimensionless). * CONSTANTS[78] is g_Ca in component calcium_current (cm_per_second). * CONSTANTS[132] is g_Cat in component calcium_current (cm3_per_second). * CONSTANTS[79] is fCat in component calcium_current (dimensionless). * ALGEBRAIC[67] is E_K in component Ca_independent_transient_outward_K_current (millivolt). * CONSTANTS[80] is a in component Ca_independent_transient_outward_K_current (dimensionless). * CONSTANTS[81] is b in component Ca_independent_transient_outward_K_current (dimensionless). * CONSTANTS[82] is g_Kto in component Ca_independent_transient_outward_K_current (milliS_per_cm2). * CONSTANTS[133] is g_Ktot in component Ca_independent_transient_outward_K_current (milliS). * CONSTANTS[83] is fKtot in component Ca_independent_transient_outward_K_current (dimensionless). * STATES[35] is r in component Ca_independent_transient_outward_K_current_r_gate (dimensionless). * STATES[36] is s in component Ca_independent_transient_outward_K_current_s_gate (dimensionless). * STATES[37] is s_slow in component Ca_independent_transient_outward_K_current_s_slow_gate (dimensionless). * ALGEBRAIC[70] is tau_r in component Ca_independent_transient_outward_K_current_r_gate (second). * ALGEBRAIC[69] is r_max in component Ca_independent_transient_outward_K_current_r_gate (dimensionless). * ALGEBRAIC[72] is tau_t in component Ca_independent_transient_outward_K_current_s_gate (second). * ALGEBRAIC[71] is s_max in component Ca_independent_transient_outward_K_current_s_gate (dimensionless). * ALGEBRAIC[74] is tau_s_slow in component Ca_independent_transient_outward_K_current_s_slow_gate (second). * ALGEBRAIC[73] is s_slow_max in component Ca_independent_transient_outward_K_current_s_slow_gate (dimensionless). * CONSTANTS[84] is g_Kss in component steady_state_outward_K_current (milliS_per_cm2). * CONSTANTS[134] is g_Ksst in component steady_state_outward_K_current (milliS). * CONSTANTS[85] is fKsst in component steady_state_outward_K_current (dimensionless). * STATES[38] is r_ss in component steady_state_outward_K_current_r_ss_gate (dimensionless). * STATES[39] is s_ss in component steady_state_outward_K_current_s_ss_gate (dimensionless). * ALGEBRAIC[77] is tau_r_ss in component steady_state_outward_K_current_r_ss_gate (second). * ALGEBRAIC[76] is r_ss_max in component steady_state_outward_K_current_r_ss_gate (dimensionless). * CONSTANTS[110] is tau_s_ss in component steady_state_outward_K_current_s_ss_gate (second). * ALGEBRAIC[78] is s_ss_max in component steady_state_outward_K_current_s_ss_gate (dimensionless). * CONSTANTS[86] is g_K1 in component inward_rectifier (milliS_per_cm2). * CONSTANTS[135] is g_K1t in component inward_rectifier (milliS). * CONSTANTS[87] is fK1t in component inward_rectifier (dimensionless). * CONSTANTS[88] is g_f in component hyperpolarisation_activated_current (milliS_per_cm2). * CONSTANTS[136] is g_ft in component hyperpolarisation_activated_current (milliS). * CONSTANTS[89] is fft in component hyperpolarisation_activated_current (dimensionless). * CONSTANTS[90] is f_Na in component hyperpolarisation_activated_current (dimensionless). * CONSTANTS[111] is f_K in component hyperpolarisation_activated_current (dimensionless). * STATES[40] is y in component hyperpolarisation_activated_current_y_gate (dimensionless). * ALGEBRAIC[84] is tau_y in component hyperpolarisation_activated_current_y_gate (second). * ALGEBRAIC[83] is y_infinity in component hyperpolarisation_activated_current_y_gate (dimensionless). * CONSTANTS[91] is g_B_Ca in component background_currents (milliS_per_cm2). * CONSTANTS[92] is g_B_Na in component background_currents (milliS_per_cm2). * CONSTANTS[93] is g_B_K in component background_currents (milliS_per_cm2). * CONSTANTS[137] is g_B_Cat in component background_currents (milliS). * CONSTANTS[138] is g_B_Nat in component background_currents (milliS). * CONSTANTS[139] is g_B_Kt in component background_currents (milliS). * CONSTANTS[94] is fCabt in component background_currents (dimensionless). * CONSTANTS[95] is fNabt in component background_currents (dimensionless). * CONSTANTS[96] is fKbt in component background_currents (dimensionless). * CONSTANTS[97] is E_Ca in component background_currents (millivolt). * CONSTANTS[98] is i_NaK_max in component sodium_potassium_pump (microA_per_cm2). * CONSTANTS[140] is i_NaK_max_t in component sodium_potassium_pump (microA). * CONSTANTS[99] is fNaKt in component sodium_potassium_pump (dimensionless). * CONSTANTS[100] is K_m_K in component sodium_potassium_pump (millimolar). * CONSTANTS[101] is K_m_Na in component sodium_potassium_pump (millimolar). * ALGEBRAIC[89] is sigma in component sodium_potassium_pump (dimensionless). * CONSTANTS[102] is i_CaP_max in component sarcolemmal_calcium_pump_current (microA_per_cm2). * CONSTANTS[141] is i_CaP_max_t in component sarcolemmal_calcium_pump_current (microA). * CONSTANTS[103] is fCaPt in component sarcolemmal_calcium_pump_current (dimensionless). * CONSTANTS[104] is i_NaCa_max in component Na_Ca_ion_exchanger_current (microA_per_cm2). * CONSTANTS[142] is i_NaCa_max_t in component Na_Ca_ion_exchanger_current (microA). * CONSTANTS[105] is fNaCat in component Na_Ca_ion_exchanger_current (dimensionless). * RATES[4] is d/dt F1 in component SR_Ca_release_channel (dimensionless). * RATES[2] is d/dt F2 in component SR_Ca_release_channel (dimensionless). * RATES[3] is d/dt F3 in component SR_Ca_release_channel (dimensionless). * RATES[5] is d/dt F4 in component SR_Ca_release_channel (dimensionless). * RATES[10] is d/dt BTRH in component intracellular_and_SR_Ca_fluxes (millimolar). * RATES[11] is d/dt BTRL in component intracellular_and_SR_Ca_fluxes (millimolar). * RATES[12] is d/dt Na_i in component ion_concentrations (millimolar). * RATES[14] is d/dt Na_t in component ion_concentrations (millimolar). * RATES[13] is d/dt K_i in component ion_concentrations (millimolar). * RATES[16] is d/dt K_t in component ion_concentrations (millimolar). * RATES[8] is d/dt Ca_i in component ion_concentrations (millimolar). * RATES[15] is d/dt Ca_t in component ion_concentrations (millimolar). * RATES[6] is d/dt Ca_ss in component ion_concentrations (millimolar). * RATES[7] is d/dt CaSRrel in component ion_concentrations (millimolar). * RATES[9] is d/dt CaSRup in component ion_concentrations (millimolar). * RATES[0] is d/dt Vm_s in component membrane (millivolt). * RATES[17] is d/dt m in component sodium_current_m_gate (dimensionless). * RATES[18] is d/dt h in component sodium_current_h_gate (dimensionless). * RATES[19] is d/dt Co in component calcium_current (dimensionless). * RATES[21] is d/dt C1 in component calcium_current (dimensionless). * RATES[22] is d/dt C2 in component calcium_current (dimensionless). * RATES[20] is d/dt C_cast in component calcium_current (dimensionless). * RATES[23] is d/dt r in component Ca_independent_transient_outward_K_current_r_gate (dimensionless). * RATES[24] is d/dt s in component Ca_independent_transient_outward_K_current_s_gate (dimensionless). * RATES[25] is d/dt s_slow in component Ca_independent_transient_outward_K_current_s_slow_gate (dimensionless). * RATES[26] is d/dt r_ss in component steady_state_outward_K_current_r_ss_gate (dimensionless). * RATES[27] is d/dt s_ss in component steady_state_outward_K_current_s_ss_gate (dimensionless). * RATES[28] is d/dt y in component hyperpolarisation_activated_current_y_gate (dimensionless). * RATES[1] is d/dt Vm_t in component membrane (millivolt). * RATES[29] is d/dt m in component sodium_current_m_gate (dimensionless). * RATES[30] is d/dt h in component sodium_current_h_gate (dimensionless). * RATES[31] is d/dt Co in component calcium_current (dimensionless). * RATES[33] is d/dt C1 in component calcium_current (dimensionless). * RATES[34] is d/dt C2 in component calcium_current (dimensionless). * RATES[32] is d/dt C_cast in component calcium_current (dimensionless). * RATES[35] is d/dt r in component Ca_independent_transient_outward_K_current_r_gate (dimensionless). * RATES[36] is d/dt s in component Ca_independent_transient_outward_K_current_s_gate (dimensionless). * RATES[37] is d/dt s_slow in component Ca_independent_transient_outward_K_current_s_slow_gate (dimensionless). * RATES[38] is d/dt r_ss in component steady_state_outward_K_current_r_ss_gate (dimensionless). * RATES[39] is d/dt s_ss in component steady_state_outward_K_current_s_ss_gate (dimensionless). * RATES[40] is d/dt y in component hyperpolarisation_activated_current_y_gate (dimensionless). * There are a total of 1 condition variables. */ void initConsts(double* CONSTANTS, double* RATES, double *STATES) { CONSTANTS[0] = 8310; CONSTANTS[1] = 295; CONSTANTS[2] = 96500; CONSTANTS[3] = 140; CONSTANTS[4] = 1.2; CONSTANTS[5] = 5.4; CONSTANTS[6] = 83.33; CONSTANTS[7] = 150e-7; CONSTANTS[8] = 30000000; CONSTANTS[9] = 0.0001; CONSTANTS[10] = 20.0; STATES[0] = -7.9709547e1; STATES[1] = -7.9709536e1; CONSTANTS[11] = 12.15e12; CONSTANTS[12] = 576; CONSTANTS[13] = 4.05e9; CONSTANTS[14] = 1930; CONSTANTS[15] = 100; CONSTANTS[16] = 0.8; STATES[2] = 3.8333331e-4; STATES[3] = 6.4516879e-11; STATES[4] = 6.7606483e-1; STATES[5] = 3.2355462e-1; STATES[6] = 4.3112114e-5; STATES[7] = 2.2638169e-1; CONSTANTS[17] = 0.000168; CONSTANTS[18] = 3.29; CONSTANTS[19] = 0.4; CONSTANTS[20] = 0.9; CONSTANTS[21] = 1; CONSTANTS[22] = 1.2; CONSTANTS[23] = 1; STATES[8] = 3.5486498e-5; STATES[9] = 2.2755058e-1; CONSTANTS[24] = 0.14; CONSTANTS[25] = 0.07; CONSTANTS[26] = 0.02; CONSTANTS[27] = 0.008; STATES[10] = 9.2804169e-1; STATES[11] = 3.4317829e-2; CONSTANTS[28] = 20000; CONSTANTS[29] = 0.07; CONSTANTS[30] = 40000; CONSTANTS[31] = 40; STATES[12] = 6.9435814e0; STATES[13] = 1.3753311e2; STATES[14] = 1.4001386e2; STATES[15] = 1.2271399e0; STATES[16] = 5.3627676e0; CONSTANTS[32] = 0.00238; CONSTANTS[33] = 0.8; CONSTANTS[34] = 0.00015; CONSTANTS[35] = 0.05; CONSTANTS[36] = 15; CONSTANTS[37] = 10; CONSTANTS[38] = 0.008; CONSTANTS[39] = 1; CONSTANTS[40] = 0; CONSTANTS[41] = 0.15; CONSTANTS[42] = 0.5; CONSTANTS[43] = 0.15; CONSTANTS[44] = 10.0; CONSTANTS[45] = 0.56; STATES[17] = 2.1832558e-6; STATES[18] = 5.8232781e-1; STATES[19] = 2.5436465e-6; STATES[20] = 9.9570063e-1; STATES[21] = 9.9994546e-1; STATES[22] = 9.9994546e-1; CONSTANTS[46] = 0.009; CONSTANTS[47] = 0.00021; CONSTANTS[48] = 0.87; CONSTANTS[49] = 0.886; CONSTANTS[50] = 0.114; CONSTANTS[51] = 0.35; CONSTANTS[52] = 0.56; STATES[23] = 2.3485072e-3; STATES[24] = 9.8315843e-1; STATES[25] = 6.7483370e-1; CONSTANTS[53] = 0.07; CONSTANTS[54] = 0.76; STATES[26] = 3.1079213e-3; STATES[27] = 3.0773393e-1; CONSTANTS[55] = 0.24; CONSTANTS[56] = 0.56; CONSTANTS[57] = 0.0145; CONSTANTS[58] = 0.56; CONSTANTS[59] = 0.2; STATES[28] = 3.4357356e-3; CONSTANTS[60] = 0.000648; CONSTANTS[61] = 0.0008015; CONSTANTS[62] = 0.00138; CONSTANTS[63] = 0.56; CONSTANTS[64] = 0.56; CONSTANTS[65] = 0.56; CONSTANTS[66] = 65; CONSTANTS[67] = 1; CONSTANTS[68] = 0.59; CONSTANTS[69] = 1.5; CONSTANTS[70] = 10; CONSTANTS[71] = 0.85; CONSTANTS[72] = 0.56; CONSTANTS[73] = 1.8e-4; CONSTANTS[74] = 0.81; CONSTANTS[75] = 10.0; CONSTANTS[76] = 0.56; STATES[29] = 2.1832694e-6; STATES[30] = 5.8232717e-1; STATES[31] = 2.5436520e-6; STATES[32] = 9.9570063e-1; STATES[33] = 9.9785393e-1; STATES[34] = 9.9994546e-1; CONSTANTS[77] = 0.009; CONSTANTS[78] = 0.00021; CONSTANTS[79] = 0.87; CONSTANTS[80] = 0.886; CONSTANTS[81] = 0.114; CONSTANTS[82] = 0.35; CONSTANTS[83] = 0.56; STATES[35] = 2.3485094e-3; STATES[36] = 9.8315865e-1; STATES[37] = 6.7478532e-1; CONSTANTS[84] = 0.07; CONSTANTS[85] = 0.76; STATES[38] = 3.1079241e-3; STATES[39] = 3.0773368e-1; CONSTANTS[86] = 0.24; CONSTANTS[87] = 0.56; CONSTANTS[88] = 0.0145; CONSTANTS[89] = 0.56; CONSTANTS[90] = 0.2; STATES[40] = 3.4357175e-3; CONSTANTS[91] = 0.000648; CONSTANTS[92] = 0.0008015; CONSTANTS[93] = 0.00138; CONSTANTS[94] = 0.56; CONSTANTS[95] = 0.56; CONSTANTS[96] = 0.56; CONSTANTS[97] = 65; CONSTANTS[98] = 1; CONSTANTS[99] = 0.59; CONSTANTS[100] = 1.5; CONSTANTS[101] = 10; CONSTANTS[102] = 0.85; CONSTANTS[103] = 0.56; CONSTANTS[104] = 1.8e-4; CONSTANTS[105] = 0.81; CONSTANTS[106] = CONSTANTS[9]/7850.00; CONSTANTS[107] = 2.10000; CONSTANTS[108] = 1.00000 - CONSTANTS[59]; CONSTANTS[109] = (exp(CONSTANTS[3]/67.3000) - 1.00000)/7.00000; CONSTANTS[110] = 2.10000; CONSTANTS[111] = 1.00000 - CONSTANTS[90]; CONSTANTS[112] = CONSTANTS[106]*7.50000e-05; CONSTANTS[113] = CONSTANTS[106]*0.585000; CONSTANTS[114] = CONSTANTS[106]*0.0315000; CONSTANTS[115] = CONSTANTS[106]*0.00350000; CONSTANTS[116] = CONSTANTS[9] - 4400.00*CONSTANTS[106]; CONSTANTS[117] = CONSTANTS[9] - CONSTANTS[116]; CONSTANTS[118] = CONSTANTS[8]*CONSTANTS[116]; CONSTANTS[119] = CONSTANTS[44]*(CONSTANTS[116]+CONSTANTS[117])*(1.00000 - CONSTANTS[45]); CONSTANTS[120] = CONSTANTS[47]*(CONSTANTS[116]+CONSTANTS[117])*(1.00000 - CONSTANTS[48]); CONSTANTS[121] = CONSTANTS[51]*(CONSTANTS[116]+CONSTANTS[117])*(1.00000 - CONSTANTS[52]); CONSTANTS[122] = CONSTANTS[53]*(CONSTANTS[116]+CONSTANTS[117])*(1.00000 - CONSTANTS[54]); CONSTANTS[123] = CONSTANTS[55]*(CONSTANTS[116]+CONSTANTS[117])*(1.00000 - CONSTANTS[56]); CONSTANTS[124] = CONSTANTS[57]*(CONSTANTS[116]+CONSTANTS[117])*(1.00000 - CONSTANTS[58]); CONSTANTS[125] = CONSTANTS[60]*(CONSTANTS[116]+CONSTANTS[117])*(1.00000 - CONSTANTS[63]); CONSTANTS[126] = CONSTANTS[61]*(CONSTANTS[116]+CONSTANTS[117])*(1.00000 - CONSTANTS[64]); CONSTANTS[127] = CONSTANTS[62]*(CONSTANTS[116]+CONSTANTS[117])*(1.00000 - CONSTANTS[65]); CONSTANTS[128] = CONSTANTS[67]*(CONSTANTS[116]+CONSTANTS[117])*(1.00000 - CONSTANTS[68]); CONSTANTS[129] = CONSTANTS[71]*(CONSTANTS[116]+CONSTANTS[117])*(1.00000 - CONSTANTS[72]); CONSTANTS[130] = CONSTANTS[73]*(CONSTANTS[116]+CONSTANTS[117])*(1.00000 - CONSTANTS[74]); CONSTANTS[131] = CONSTANTS[75]*(CONSTANTS[116]+CONSTANTS[117])*CONSTANTS[76]; CONSTANTS[132] = CONSTANTS[78]*(CONSTANTS[116]+CONSTANTS[117])*CONSTANTS[79]; CONSTANTS[133] = CONSTANTS[82]*(CONSTANTS[116]+CONSTANTS[117])*CONSTANTS[83]; CONSTANTS[134] = CONSTANTS[84]*(CONSTANTS[116]+CONSTANTS[117])*CONSTANTS[85]; CONSTANTS[135] = CONSTANTS[86]*(CONSTANTS[116]+CONSTANTS[117])*CONSTANTS[87]; CONSTANTS[136] = CONSTANTS[88]*(CONSTANTS[116]+CONSTANTS[117])*CONSTANTS[89]; CONSTANTS[137] = CONSTANTS[91]*(CONSTANTS[116]+CONSTANTS[117])*CONSTANTS[94]; CONSTANTS[138] = CONSTANTS[92]*(CONSTANTS[116]+CONSTANTS[117])*CONSTANTS[95]; CONSTANTS[139] = CONSTANTS[93]*(CONSTANTS[116]+CONSTANTS[117])*CONSTANTS[96]; CONSTANTS[140] = CONSTANTS[98]*(CONSTANTS[116]+CONSTANTS[117])*CONSTANTS[99]; CONSTANTS[141] = CONSTANTS[102]*(CONSTANTS[116]+CONSTANTS[117])*CONSTANTS[103]; CONSTANTS[142] = CONSTANTS[104]*(CONSTANTS[116]+CONSTANTS[117])*CONSTANTS[105]; CONSTANTS[143] = CONSTANTS[117]/( 2.00000*3.14159*CONSTANTS[7]*CONSTANTS[118]); CONSTANTS[144] = ( CONSTANTS[6]*(CONSTANTS[143]/2.00000))/( 3.14159*pow(CONSTANTS[7], 2.00000)*CONSTANTS[118]); CONSTANTS[145] = 3.14159*pow(CONSTANTS[7], 2.00000)*CONSTANTS[143]*CONSTANTS[118]; CONSTANTS[146] = CONSTANTS[117]*1.00000; CONSTANTS[147] = CONSTANTS[116]*1.00000; RATES[4] = 0.1001; RATES[2] = 0.1001; RATES[3] = 0.1001; RATES[5] = 0.1001; RATES[10] = 0.1001; RATES[11] = 0.1001; RATES[12] = 0.1001; RATES[14] = 0.1001; RATES[13] = 0.1001; RATES[16] = 0.1001; RATES[8] = 0.1001; RATES[15] = 0.1001; RATES[6] = 0.1001; RATES[7] = 0.1001; RATES[9] = 0.1001; RATES[0] = 0.1001; RATES[17] = 0.1001; RATES[18] = 0.1001; RATES[19] = 0.1001; RATES[21] = 0.1001; RATES[22] = 0.1001; RATES[20] = 0.1001; RATES[23] = 0.1001; RATES[24] = 0.1001; RATES[25] = 0.1001; RATES[26] = 0.1001; RATES[27] = 0.1001; RATES[28] = 0.1001; RATES[1] = 0.1001; RATES[29] = 0.1001; RATES[30] = 0.1001; RATES[31] = 0.1001; RATES[33] = 0.1001; RATES[34] = 0.1001; RATES[32] = 0.1001; RATES[35] = 0.1001; RATES[36] = 0.1001; RATES[37] = 0.1001; RATES[38] = 0.1001; RATES[39] = 0.1001; RATES[40] = 0.1001; } void computeResiduals(double VOI, double* CONSTANTS, double* RATES, double* OLDRATES, double* STATES, double* OLDSTATES, double* ALGEBRAIC, double* CONDVARS) { resid[0] = RATES[4] - - CONSTANTS[11]*pow(STATES[6], 4.00000)*STATES[4]+ CONSTANTS[12]*STATES[2]; resid[1] = RATES[2] - ( CONSTANTS[11]*pow(STATES[6], 4.00000)*STATES[4] - ( CONSTANTS[12]*STATES[2]+ CONSTANTS[13]*pow(STATES[6], 3.00000)*STATES[2]+ CONSTANTS[15]*STATES[2]))+ CONSTANTS[14]*STATES[3]+ CONSTANTS[16]*STATES[5]; resid[2] = RATES[3] - CONSTANTS[13]*pow(STATES[6], 3.00000)*STATES[2] - CONSTANTS[14]*STATES[3]; resid[3] = RATES[5] - CONSTANTS[15]*STATES[2] - CONSTANTS[16]*STATES[5]; resid[4] = RATES[10] - ALGEBRAIC[7]; resid[5] = RATES[11] - ALGEBRAIC[8]; resid[6] = RATES[12] - - (ALGEBRAIC[15]+ALGEBRAIC[54]+ALGEBRAIC[46]+ALGEBRAIC[85]+ ALGEBRAIC[52]*3.00000+ ALGEBRAIC[92]*3.00000+ ALGEBRAIC[50]*3.00000+ ALGEBRAIC[90]*3.00000)/( CONSTANTS[113]*CONSTANTS[2]); resid[7] = RATES[14] - ((ALGEBRAIC[54]+ALGEBRAIC[85]+ ALGEBRAIC[92]*3.00000+ ALGEBRAIC[90]*3.00000)/(CONSTANTS[2] - ALGEBRAIC[11]))/CONSTANTS[145]; resid[8] = RATES[13] - - (- ALGEBRAIC[10]+ALGEBRAIC[42]+ALGEBRAIC[81]+ALGEBRAIC[36]+ALGEBRAIC[75]+ALGEBRAIC[40]+ALGEBRAIC[79]+ALGEBRAIC[48]+ALGEBRAIC[87]+ ALGEBRAIC[50]*- 2.00000+ ALGEBRAIC[90]*- 2.00000+ALGEBRAIC[29]+ALGEBRAIC[68])/( CONSTANTS[113]*CONSTANTS[2]); resid[9] = RATES[16] - ((ALGEBRAIC[81]+ALGEBRAIC[75]+ALGEBRAIC[79]+ALGEBRAIC[87]+ ALGEBRAIC[90]*- 2.00000+ALGEBRAIC[68])/(CONSTANTS[2] - ALGEBRAIC[13]))/CONSTANTS[145]; resid[10] = RATES[8] - (1.00000/(1.00000+ CONSTANTS[35]*(CONSTANTS[32]/pow(CONSTANTS[32]+STATES[8], 2.00000))))*((( -2.00000*(ALGEBRAIC[52]+ALGEBRAIC[92])+(ALGEBRAIC[47]+ALGEBRAIC[86]+ALGEBRAIC[51]+ALGEBRAIC[91]))/( -2.00000*CONSTANTS[113]*CONSTANTS[2])+((( (STATES[6] - STATES[8])*CONSTANTS[113])/CONSTANTS[38]+ALGEBRAIC[1]) - ALGEBRAIC[4])/CONSTANTS[113]) - ( ALGEBRAIC[7]*CONSTANTS[24]+ ALGEBRAIC[8]*CONSTANTS[25])); resid[11] = RATES[15] - ((ALGEBRAIC[66]+ALGEBRAIC[91]+ALGEBRAIC[86]+ ALGEBRAIC[92]*- 2.00000)/( 2.00000*CONSTANTS[2] - ALGEBRAIC[12]))/CONSTANTS[145]; resid[12] = RATES[6] - (1.00000/(1.00000+ CONSTANTS[35]*(CONSTANTS[32]/pow(CONSTANTS[32]+STATES[6], 2.00000))))*(- (ALGEBRAIC[27]+ALGEBRAIC[66])/(( 2.00000*CONSTANTS[112]*CONSTANTS[2]+ALGEBRAIC[1]/CONSTANTS[112]) - (( (STATES[6] - STATES[8])*CONSTANTS[113])/CONSTANTS[38])/CONSTANTS[112])); resid[13] = RATES[7] - (1.00000/(1.00000+( CONSTANTS[36]*CONSTANTS[33])/pow(CONSTANTS[33]+STATES[7], 2.00000)))*(ALGEBRAIC[5] - ALGEBRAIC[1]); resid[14] = RATES[9] - ALGEBRAIC[4] - ALGEBRAIC[5]; resid[15] = RATES[0] - 1000.00*(((ALGEBRAIC[10]+ALGEBRAIC[0]) - (ALGEBRAIC[15]+ALGEBRAIC[27]+ALGEBRAIC[29]+ALGEBRAIC[36]+ALGEBRAIC[43]+ALGEBRAIC[40]+ALGEBRAIC[49]+ALGEBRAIC[50]+ALGEBRAIC[52]+ALGEBRAIC[51]))/CONSTANTS[147]); resid[16] = RATES[17] - ALGEBRAIC[16]*(1.00000 - STATES[17]) - ALGEBRAIC[17]*STATES[17]; resid[17] = RATES[18] - ALGEBRAIC[18]*(1.00000 - STATES[18]) - ALGEBRAIC[19]*STATES[18]; resid[18] = RATES[19] - (ALGEBRAIC[20] - STATES[19])/ALGEBRAIC[21]; resid[19] = RATES[21] - (ALGEBRAIC[22] - STATES[21])/ALGEBRAIC[23]; resid[20] = RATES[22] - (ALGEBRAIC[24] - STATES[22])/ALGEBRAIC[25]; resid[21] = RATES[20] - (ALGEBRAIC[26] - STATES[20])/CONSTANTS[46]; resid[22] = RATES[23] - (ALGEBRAIC[30] - STATES[23])/ALGEBRAIC[31]; resid[23] = RATES[24] - (ALGEBRAIC[32] - STATES[24])/ALGEBRAIC[33]; resid[24] = RATES[25] - (ALGEBRAIC[34] - STATES[25])/ALGEBRAIC[35]; resid[25] = RATES[26] - (ALGEBRAIC[37] - STATES[26])/ALGEBRAIC[38]; resid[26] = RATES[27] - (ALGEBRAIC[39] - STATES[27])/CONSTANTS[107]; resid[27] = RATES[28] - (ALGEBRAIC[44] - STATES[28])/ALGEBRAIC[45]; resid[28] = RATES[1] - 1000.00*(- (ALGEBRAIC[0]+ALGEBRAIC[54]+ALGEBRAIC[66]+ALGEBRAIC[68]+ALGEBRAIC[75]+ALGEBRAIC[82]+ALGEBRAIC[79]+ALGEBRAIC[88]+ALGEBRAIC[90]+ALGEBRAIC[92]+ALGEBRAIC[91])/CONSTANTS[146]); resid[29] = RATES[29] - ALGEBRAIC[55]*(1.00000 - STATES[29]) - ALGEBRAIC[56]*STATES[29]; resid[30] = RATES[30] - ALGEBRAIC[57]*(1.00000 - STATES[30]) - ALGEBRAIC[58]*STATES[30]; resid[31] = RATES[31] - (ALGEBRAIC[59] - STATES[31])/ALGEBRAIC[60]; resid[32] = RATES[33] - (ALGEBRAIC[61] - STATES[33])/ALGEBRAIC[62]; resid[33] = RATES[34] - (ALGEBRAIC[63] - STATES[34])/ALGEBRAIC[64]; resid[34] = RATES[32] - (ALGEBRAIC[65] - STATES[32])/CONSTANTS[77]; resid[35] = RATES[35] - (ALGEBRAIC[69] - STATES[35])/ALGEBRAIC[70]; resid[36] = RATES[36] - (ALGEBRAIC[71] - STATES[36])/ALGEBRAIC[72]; resid[37] = RATES[37] - (ALGEBRAIC[73] - STATES[37])/ALGEBRAIC[74]; resid[38] = RATES[38] - (ALGEBRAIC[76] - STATES[38])/ALGEBRAIC[77]; resid[39] = RATES[39] - (ALGEBRAIC[78] - STATES[39])/CONSTANTS[110]; resid[40] = RATES[40] - (ALGEBRAIC[83] - STATES[40])/ALGEBRAIC[84]; } void computeVariables(double VOI, double* CONSTANTS, double* RATES, double* STATES, double* ALGEBRAIC) { ALGEBRAIC[6] = (STATES[6] - STATES[8])/CONSTANTS[27]; ALGEBRAIC[9] = ALGEBRAIC[7]+ALGEBRAIC[8]; ALGEBRAIC[41] = CONSTANTS[124]*STATES[28]*CONSTANTS[59]*(STATES[0] - ALGEBRAIC[14]); ALGEBRAIC[80] = CONSTANTS[136]*STATES[40]*CONSTANTS[90]*(STATES[1] - ALGEBRAIC[53]); } void computeEssentialVariables(double VOI, double* CONSTANTS, double* RATES, double* STATES, double* ALGEBRAIC) { ALGEBRAIC[0] = 1000.00*((STATES[0] - STATES[1])/CONSTANTS[10]); ALGEBRAIC[1] = 1800.00*(STATES[2]+STATES[3])*(STATES[7] - STATES[6]); ALGEBRAIC[2] = pow(STATES[8]/CONSTANTS[17], CONSTANTS[22]); ALGEBRAIC[3] = pow(STATES[9]/CONSTANTS[18], CONSTANTS[23]); ALGEBRAIC[4] = ( CONSTANTS[21]*( CONSTANTS[19]*ALGEBRAIC[2] - CONSTANTS[20]*ALGEBRAIC[3]))/(1.00000+ALGEBRAIC[2]+ALGEBRAIC[3]); ALGEBRAIC[5] = (STATES[9] - STATES[7])/CONSTANTS[26]; ALGEBRAIC[7] = CONSTANTS[28]*STATES[8]*(1.00000 - STATES[10]) - CONSTANTS[29]*STATES[10]; ALGEBRAIC[8] = CONSTANTS[30]*STATES[8]*(1.00000 - STATES[11]) - CONSTANTS[31]*STATES[11]; ALGEBRAIC[10] = (CONSTANTS[39]==1.00000&&CONDVAR[0]<0.00000 ? 52.0000*(CONSTANTS[116]+CONSTANTS[117]) : 0.00000); ALGEBRAIC[11] = ( 1.00000*CONSTANTS[145])/( CONSTANTS[41]*(STATES[14] - CONSTANTS[3])); ALGEBRAIC[12] = ( 1.00000*CONSTANTS[145])/( CONSTANTS[42]*(STATES[15] - CONSTANTS[4])); ALGEBRAIC[13] = ( 1.00000*CONSTANTS[145])/( CONSTANTS[43]*(STATES[16] - CONSTANTS[5])); ALGEBRAIC[15] = CONSTANTS[119]*pow(STATES[17], 3.00000)*STATES[18]*(STATES[0] - arbitrary_log((CONSTANTS[3]+ 0.120000*CONSTANTS[5])/(STATES[12]+ 0.120000*STATES[13]), 10)*(( CONSTANTS[0]*CONSTANTS[1])/CONSTANTS[2])); ALGEBRAIC[16] = ( 117.260*(STATES[0]+59.3000))/(1.00000 - exp( - 0.550000*(STATES[0]+59.3000))); ALGEBRAIC[17] = 3800.00*exp( - 0.0720000*(STATES[0]+61.0000)); ALGEBRAIC[18] = 284.400/(1.00000+exp( 0.0812000*(STATES[0]+115.900))); ALGEBRAIC[19] = ( 18.7700*(STATES[0]+64.4000))/(1.00000 - exp( - 0.220000*(STATES[0]+64.4000))); ALGEBRAIC[20] = 1.00000/(1.00000+exp((STATES[0]+15.3000)/- 5.00000)); ALGEBRAIC[21] = 0.00305000*exp( - 0.00450000*pow(STATES[0]+7.00000, 2.00000))+ 0.00105000*exp( - 0.00200000*pow(STATES[0] - 18.0000, 2.00000))+0.000250000; ALGEBRAIC[22] = 1.00000/(1.00000+exp((STATES[0]+26.7000)/5.40000)); ALGEBRAIC[23] = 0.105000*exp(- pow((STATES[0]+45.0000)/12.0000, 2.00000))+0.0400000/(1.00000+exp((- STATES[0]+25.0000)/25.0000))+0.0150000/(1.00000+exp((STATES[0]+75.0000)/25.0000))+0.00170000; ALGEBRAIC[24] = 1.00000/(1.00000+exp((STATES[0]+26.7000)/5.40000)); ALGEBRAIC[25] = 0.0410000*exp(- pow((STATES[0]+47.0000)/12.0000, 2.00000))+0.0800000/(1.00000+exp((STATES[0]+55.0000)/- 5.00000))+0.0150000/(1.00000+exp((STATES[0]+75.0000)/25.0000))+0.00170000; ALGEBRAIC[26] = 1.00000/(1.00000+STATES[6]/0.0100000); ALGEBRAIC[27] = CONSTANTS[120]*4.00000*(( STATES[0]*pow(CONSTANTS[2], 2.00000))/( CONSTANTS[0]*CONSTANTS[1]))*(( STATES[6]*exp(( 2.00000*STATES[0]*pow(CONSTANTS[2], 2.00000))/( CONSTANTS[0]*CONSTANTS[1])) - 0.341000*CONSTANTS[4])/(exp(( 2.00000*STATES[0]*pow(CONSTANTS[2], 2.00000))/( CONSTANTS[0]*CONSTANTS[1])) - 1.00000))*STATES[19]*( (0.900000+STATES[20]/10.0000)*STATES[21]+ (0.100000+STATES[20]/10.0000)*STATES[22]); ALGEBRAIC[28] = (( CONSTANTS[0]*CONSTANTS[1])/CONSTANTS[2])*log(CONSTANTS[5]/STATES[13]); ALGEBRAIC[29] = CONSTANTS[121]*STATES[23]*( CONSTANTS[49]*STATES[24]+ CONSTANTS[50]*STATES[25])*(STATES[0] - ALGEBRAIC[28]); ALGEBRAIC[30] = 1.00000/(1.00000+exp((STATES[0]+10.6000)/- 11.4200)); ALGEBRAIC[31] = 1.00000/( 45.1600*exp( 0.0357700*(STATES[0]+50.0000))+ 98.9000*exp( - 0.100000*(STATES[0]+38.0000))); ALGEBRAIC[32] = 1.00000/(1.00000+exp((STATES[0]+45.3000)/6.88410)); ALGEBRAIC[33] = 0.350000*exp(- pow( 0.0666000*(STATES[0]+70.0000), 2.00000))+0.0350000; ALGEBRAIC[34] = 1.00000/(1.00000+exp((STATES[0]+45.3000)/6.88410)); ALGEBRAIC[35] = 3.70000*exp(- pow( 0.0333000*(STATES[0]+70.0000), 2.00000))+0.0350000; ALGEBRAIC[36] = CONSTANTS[122]*STATES[26]*STATES[27]*(STATES[0] - ALGEBRAIC[28]); ALGEBRAIC[37] = 1.00000/(1.00000+exp(- (STATES[0]+11.5000)/11.8200)); ALGEBRAIC[38] = 10.0000/( 45.1600*exp( 0.0357700*(STATES[0]+50.0000))+ 98.9000*exp( - 0.100000*(STATES[0]+38.0000))); ALGEBRAIC[39] = 1.00000/(1.00000+exp((STATES[0]+87.5000)/10.3000)); ALGEBRAIC[40] = (( CONSTANTS[123]*(STATES[0] - (ALGEBRAIC[28]+1.73000)))/(1.00000+exp( (( 1.61300*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1]))*(STATES[0] - (ALGEBRAIC[28]+1.73000)))))*(1.00000+exp(- (CONSTANTS[5] - 0.998800)/0.124000)); ALGEBRAIC[42] = CONSTANTS[124]*STATES[28]*CONSTANTS[108]*(STATES[0] - ALGEBRAIC[28]); ALGEBRAIC[14] = (( CONSTANTS[0]*CONSTANTS[1])/CONSTANTS[2])*log(CONSTANTS[3]/STATES[12]); ALGEBRAIC[43] = CONSTANTS[124]*STATES[28]*( 0.200000*(STATES[0] - ALGEBRAIC[14])+ 0.800000*(STATES[0] - ALGEBRAIC[28])); ALGEBRAIC[44] = 1.00000/(1.00000+exp((STATES[0]+138.600)/10.4800)); ALGEBRAIC[45] = 1.00000/( 0.118850*exp((STATES[0]+80.0000)/28.3700)+ 0.562300*exp((STATES[0]+80.0000)/- 14.1900)); ALGEBRAIC[46] = CONSTANTS[126]*(STATES[0] - ALGEBRAIC[14]); ALGEBRAIC[47] = CONSTANTS[125]*(STATES[0] - CONSTANTS[66]); ALGEBRAIC[48] = CONSTANTS[127]*(STATES[0] - ALGEBRAIC[28]); ALGEBRAIC[49] = ALGEBRAIC[46]+ALGEBRAIC[47]+ALGEBRAIC[48]; ALGEBRAIC[50] = (( (CONSTANTS[128]/(1.00000+ 0.124500*exp(( - 0.100000*STATES[0]*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1]))+ 0.0365000*CONSTANTS[109]*exp(( - STATES[0]*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1]))))*CONSTANTS[5])/(CONSTANTS[5]+CONSTANTS[69]))/(1.00000+pow(CONSTANTS[70]/STATES[12], 1.50000)); ALGEBRAIC[51] = ( CONSTANTS[129]*STATES[8])/(STATES[8]+0.000400000); ALGEBRAIC[52] = ( CONSTANTS[130]*( exp( 0.0187000*STATES[0])*pow(STATES[12], 3.00000)*CONSTANTS[4] - exp( -0.0187000*STATES[0])*pow(CONSTANTS[3], 3.00000)*STATES[8]))/(1.00000+ 0.000100000*( STATES[8]*pow(CONSTANTS[3], 3.00000)+ CONSTANTS[4]*pow(STATES[12], 3.00000))); ALGEBRAIC[54] = CONSTANTS[131]*pow(STATES[29], 3.00000)*STATES[30]*(STATES[1] - arbitrary_log((STATES[14]+ 0.120000*STATES[16])/(STATES[12]+ 0.120000*STATES[13]), 10)*(( CONSTANTS[0]*CONSTANTS[1])/CONSTANTS[2])); ALGEBRAIC[55] = ( 117.260*(STATES[1]+59.3000))/(1.00000 - exp( - 0.550000*(STATES[1]+59.3000))); ALGEBRAIC[56] = 3800.00*exp( - 0.0720000*(STATES[1]+61.0000)); ALGEBRAIC[57] = 284.400/(1.00000+exp( 0.0812000*(STATES[1]+115.900))); ALGEBRAIC[58] = ( 18.7700*(STATES[1]+64.4000))/(1.00000 - exp( - 0.220000*(STATES[1]+64.4000))); ALGEBRAIC[59] = 1.00000/(1.00000+exp((STATES[1]+15.3000)/- 5.00000)); ALGEBRAIC[60] = 0.00305000*exp( - 0.00450000*pow(STATES[1]+7.00000, 2.00000))+ 0.00105000*exp( - 0.00200000*pow(STATES[1] - 18.0000, 2.00000))+0.000250000; ALGEBRAIC[61] = 1.00000/(1.00000+exp((STATES[1]+26.7000)/5.40000)); ALGEBRAIC[62] = 0.105000*exp(- pow((STATES[1]+45.0000)/12.0000, 2.00000))+0.0400000/(1.00000+exp((- STATES[1]+25.0000)/25.0000))+0.0150000/(1.00000+exp((STATES[1]+75.0000)/25.0000))+0.00170000; ALGEBRAIC[63] = 1.00000/(1.00000+exp((STATES[1]+26.7000)/5.40000)); ALGEBRAIC[64] = 0.0410000*exp(- pow((STATES[1]+47.0000)/12.0000, 2.00000))+0.0800000/(1.00000+exp((STATES[1]+55.0000)/- 5.00000))+0.0150000/(1.00000+exp((STATES[1]+75.0000)/25.0000))+0.00170000; ALGEBRAIC[65] = 1.00000/(1.00000+STATES[6]/0.0100000); ALGEBRAIC[66] = CONSTANTS[132]*4.00000*(( STATES[1]*pow(CONSTANTS[2], 2.00000))/( CONSTANTS[0]*CONSTANTS[1]))*(( STATES[6]*exp(( 2.00000*STATES[1]*pow(CONSTANTS[2], 2.00000))/( CONSTANTS[0]*CONSTANTS[1])) - 0.341000*STATES[15])/(exp(( 2.00000*STATES[1]*pow(CONSTANTS[2], 2.00000))/( CONSTANTS[0]*CONSTANTS[1])) - 1.00000))*STATES[31]*( (0.900000+STATES[32]/10.0000)*STATES[33]+ (0.100000+STATES[32]/10.0000)*STATES[34]); ALGEBRAIC[67] = (( CONSTANTS[0]*CONSTANTS[1])/CONSTANTS[2])*log(STATES[16]/STATES[13]); ALGEBRAIC[68] = CONSTANTS[133]*STATES[35]*( CONSTANTS[80]*STATES[36]+ CONSTANTS[81]*STATES[37])*(STATES[1] - ALGEBRAIC[67]); ALGEBRAIC[69] = 1.00000/(1.00000+exp((STATES[1]+10.6000)/- 11.4200)); ALGEBRAIC[70] = 1.00000/( 45.1600*exp( 0.0357700*(STATES[1]+50.0000))+ 98.9000*exp( - 0.100000*(STATES[1]+38.0000))); ALGEBRAIC[71] = 1.00000/(1.00000+exp((STATES[1]+45.3000)/6.88410)); ALGEBRAIC[72] = 0.350000*exp(- pow( 0.0666000*(STATES[1]+70.0000), 2.00000))+0.0350000; ALGEBRAIC[73] = 1.00000/(1.00000+exp((STATES[1]+45.3000)/6.88410)); ALGEBRAIC[74] = 3.70000*exp(- pow( 0.0333000*(STATES[1]+70.0000), 2.00000))+0.0350000; ALGEBRAIC[75] = CONSTANTS[134]*STATES[38]*STATES[39]*(STATES[1] - ALGEBRAIC[67]); ALGEBRAIC[76] = 1.00000/(1.00000+exp(- (STATES[1]+11.5000)/11.8200)); ALGEBRAIC[77] = 10.0000/( 45.1600*exp( 0.0357700*(STATES[1]+50.0000))+ 98.9000*exp( - 0.100000*(STATES[1]+38.0000))); ALGEBRAIC[78] = 1.00000/(1.00000+exp((STATES[1]+87.5000)/10.3000)); ALGEBRAIC[79] = (( CONSTANTS[135]*(STATES[1] - (ALGEBRAIC[67]+1.73000)))/(1.00000+exp( (( 1.61300*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1]))*(STATES[1] - (ALGEBRAIC[67]+1.73000)))))*(1.00000+exp(- (STATES[16] - 0.998800)/0.124000)); ALGEBRAIC[81] = CONSTANTS[136]*STATES[40]*CONSTANTS[111]*(STATES[1] - ALGEBRAIC[67]); ALGEBRAIC[53] = (( CONSTANTS[0]*CONSTANTS[1])/CONSTANTS[2])*log(STATES[14]/STATES[12]); ALGEBRAIC[82] = CONSTANTS[136]*STATES[40]*( 0.200000*(STATES[1] - ALGEBRAIC[53])+ 0.800000*(STATES[1] - ALGEBRAIC[67])); ALGEBRAIC[83] = 1.00000/(1.00000+exp((STATES[1]+138.600)/10.4800)); ALGEBRAIC[84] = 1.00000/( 0.118850*exp((STATES[1]+80.0000)/28.3700)+ 0.562300*exp((STATES[1]+80.0000)/- 14.1900)); ALGEBRAIC[85] = CONSTANTS[138]*(STATES[1] - ALGEBRAIC[53]); ALGEBRAIC[86] = CONSTANTS[137]*(STATES[1] - CONSTANTS[97]); ALGEBRAIC[87] = CONSTANTS[139]*(STATES[1] - ALGEBRAIC[67]); ALGEBRAIC[88] = ALGEBRAIC[85]+ALGEBRAIC[86]+ALGEBRAIC[87]; ALGEBRAIC[89] = (exp(STATES[14]/67.3000) - 1.00000)/7.00000; ALGEBRAIC[90] = (( (CONSTANTS[140]/(1.00000+ 0.124500*exp(( - 0.100000*STATES[1]*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1]))+ 0.0365000*ALGEBRAIC[89]*exp(( - STATES[1]*CONSTANTS[2])/( CONSTANTS[0]*CONSTANTS[1]))))*STATES[16])/(STATES[16]+CONSTANTS[100]))/(1.00000+pow(CONSTANTS[101]/STATES[12], 1.50000)); ALGEBRAIC[91] = ( CONSTANTS[141]*STATES[8])/(STATES[8]+0.000400000); ALGEBRAIC[92] = ( CONSTANTS[142]*( exp( 0.0187000*STATES[1])*pow(STATES[12], 3.00000)*STATES[15] - exp( -0.0187000*STATES[1])*pow(STATES[14], 3.00000)*STATES[8]))/(1.00000+ 0.000100000*( STATES[8]*pow(STATES[14], 3.00000)+ STATES[15]*pow(STATES[12], 3.00000))); } void getStateInformation(double* SI) { SI[0] = 1.0; SI[1] = 1.0; SI[2] = 1.0; SI[3] = 1.0; SI[4] = 1.0; SI[5] = 1.0; SI[6] = 1.0; SI[7] = 1.0; SI[8] = 1.0; SI[9] = 1.0; SI[10] = 1.0; SI[11] = 1.0; SI[12] = 1.0; SI[13] = 1.0; SI[14] = 1.0; SI[15] = 1.0; SI[16] = 1.0; SI[17] = 1.0; SI[18] = 1.0; SI[19] = 1.0; SI[20] = 1.0; SI[21] = 1.0; SI[22] = 1.0; SI[23] = 1.0; SI[24] = 1.0; SI[25] = 1.0; SI[26] = 1.0; SI[27] = 1.0; SI[28] = 1.0; SI[29] = 1.0; SI[30] = 1.0; SI[31] = 1.0; SI[32] = 1.0; SI[33] = 1.0; SI[34] = 1.0; SI[35] = 1.0; SI[36] = 1.0; SI[37] = 1.0; SI[38] = 1.0; SI[39] = 1.0; SI[40] = 1.0; } void computeRoots(double VOI, double* CONSTANTS, double* RATES, double* OLDRATES, double* STATES, double* OLDSTATES, double* ALGEBRAIC, double* CONDVARS) { CONDVAR[0] = (VOI - CONSTANTS[40]) - 0.00100000; }