# Size of variable arrays: sizeAlgebraic = 42 sizeStates = 10 sizeConstants = 47 from math import * from numpy import * def createLegends(): legend_states = [""] * sizeStates legend_rates = [""] * sizeStates legend_algebraic = [""] * sizeAlgebraic legend_voi = "" legend_constants = [""] * sizeConstants legend_voi = "time in component environment (millisecond)" legend_states[0] = "Gi in component Gi (millimolar)" legend_algebraic[4] = "Jglut in component Jglut (millimolar_per_millisecond)" legend_algebraic[6] = "Jgk in component Jgk (millimolar_per_millisecond)" legend_states[1] = "Ge in component Ge (millimolar)" legend_algebraic[1] = "G_infinity in component Ge (millimolar)" legend_constants[0] = "tau_G in component Ge (millisecond)" legend_constants[1] = "Gmax in component Ge (millimolar)" legend_constants[2] = "Gmin in component Ge (millimolar)" legend_constants[3] = "SG in component Ge (dimensionless)" legend_constants[4] = "I_ in component Ge (dimensionless)" legend_states[2] = "I in component I (dimensionless)" legend_states[3] = "G6P in component G6P (millimolar)" legend_constants[5] = "kappa in component model_parameters (dimensionless)" legend_algebraic[41] = "JPFK in component JPFK (micromolar_per_millisecond)" legend_states[4] = "FBP in component FBP (micromolar)" legend_algebraic[7] = "JGPDH in component JGPDH (micromolar_per_millisecond)" legend_algebraic[0] = "F6P in component F6P (millimolar)" legend_constants[6] = "Kglut in component Jglut (millimolar)" legend_constants[7] = "Vglut in component Jglut (millimolar_per_millisecond)" legend_constants[8] = "Kgk in component Jgk (millimolar)" legend_constants[9] = "Vgk in component Jgk (millimolar_per_millisecond)" legend_constants[10] = "ngk in component Jgk (dimensionless)" legend_constants[11] = "lambda in component JPFK (dimensionless)" legend_constants[12] = "Vmax in component JPFK (micromolar_per_millisecond)" legend_constants[46] = "w0000 in component w (dimensionless)" legend_algebraic[25] = "w1000 in component w (dimensionless)" legend_algebraic[8] = "w0100 in component w (dimensionless)" legend_algebraic[9] = "w0010 in component w (dimensionless)" legend_algebraic[27] = "w0001 in component w (dimensionless)" legend_algebraic[29] = "w1100 in component w (dimensionless)" legend_algebraic[31] = "w1010 in component w (dimensionless)" legend_algebraic[33] = "w1001 in component w (dimensionless)" legend_algebraic[34] = "w0101 in component w (dimensionless)" legend_algebraic[35] = "w0011 in component w (dimensionless)" legend_algebraic[10] = "w0110 in component w (dimensionless)" legend_algebraic[36] = "w1110 in component w (dimensionless)" legend_algebraic[37] = "w0111 in component w (dimensionless)" legend_algebraic[38] = "w1011 in component w (dimensionless)" legend_algebraic[39] = "w1101 in component w (dimensionless)" legend_algebraic[40] = "w1111 in component w (dimensionless)" legend_constants[13] = "f13 in component w (dimensionless)" legend_constants[14] = "f23 in component w (dimensionless)" legend_constants[15] = "f41 in component w (dimensionless)" legend_constants[16] = "f42 in component w (dimensionless)" legend_constants[17] = "f43 in component w (dimensionless)" legend_constants[18] = "K1 in component w (micromolar)" legend_constants[19] = "K2 in component w (micromolar)" legend_constants[20] = "K3 in component w (micromolar)" legend_constants[21] = "K4 in component w (micromolar)" legend_algebraic[23] = "AMP in component AMP (micromolar)" legend_algebraic[24] = "ATP in component ATP (micromolar)" legend_constants[22] = "Atot in component ATP (micromolar)" legend_states[5] = "ADP in component ADP (micromolar)" legend_constants[23] = "tau_a in component ADP (millisecond)" legend_constants[24] = "r in component ADP (dimensionless)" legend_constants[25] = "r1 in component ADP (micromolar)" legend_algebraic[11] = "gamma in component gamma (dimensionless)" legend_states[6] = "Ca in component Ca (micromolar)" legend_constants[26] = "v_gamma in component gamma (dimensionless)" legend_constants[27] = "k_gamma in component gamma (micromolar_per_millisecond)" legend_states[7] = "v in component membrane (millivolt)" legend_constants[28] = "cm in component membrane (femtofarad)" legend_algebraic[14] = "I_Ca in component I_Ca (picoampere)" legend_algebraic[12] = "I_K in component I_K (picoampere)" legend_algebraic[17] = "I_K_Ca in component I_K_Ca (picoampere)" legend_algebraic[32] = "I_K_ATP in component I_K_ATP (picoampere)" legend_constants[29] = "gK_ in component I_K (picosiemens)" legend_constants[30] = "vK in component model_parameters (millivolt)" legend_states[8] = "n in component n (dimensionless)" legend_algebraic[5] = "n_infinity in component n (dimensionless)" legend_algebraic[2] = "tau_n in component n (millisecond)" legend_constants[31] = "gCa_ in component I_Ca (picosiemens)" legend_constants[32] = "vCa in component model_parameters (millivolt)" legend_algebraic[13] = "m_infinity in component m (dimensionless)" legend_constants[33] = "gkCa_ in component I_K_Ca (picosiemens)" legend_algebraic[15] = "gkCa in component I_K_Ca (picosiemens)" legend_constants[34] = "KD in component I_K_Ca (micromolar)" legend_constants[35] = "gkATP_ in component I_K_ATP (picosiemens)" legend_algebraic[30] = "gkATP in component I_K_ATP (picosiemens)" legend_algebraic[28] = "o_infinity in component I_K_ATP (dimensionless)" legend_algebraic[19] = "MgADP in component I_K_ATP (micromolar)" legend_algebraic[21] = "ADP3_ in component I_K_ATP (micromolar)" legend_algebraic[26] = "ATP4_ in component I_K_ATP (micromolar)" legend_constants[36] = "fcyt in component Ca (dimensionless)" legend_algebraic[16] = "Jmem in component Jmem (micromolar_per_millisecond)" legend_algebraic[22] = "Jer in component Jer (micromolar_per_millisecond)" legend_states[9] = "Caer in component Caer (micromolar)" legend_constants[37] = "fer in component Caer (dimensionless)" legend_constants[38] = "Vcyt_Ver in component Caer (dimensionless)" legend_constants[39] = "kPMCA in component Jmem (first_order_rate_constant)" legend_constants[40] = "alpha in component Jmem (micromolar_per_millisecond)" legend_algebraic[20] = "Jleak in component Jleak (micromolar_per_millisecond)" legend_algebraic[18] = "JSERCA in component JSERCA (micromolar_per_millisecond)" legend_constants[41] = "kSERCA in component JSERCA (first_order_rate_constant)" legend_constants[42] = "pleak in component Jleak (first_order_rate_constant)" legend_algebraic[3] = "I_infinity in component I (dimensionless)" legend_constants[43] = "tau_I in component I (millisecond)" legend_constants[44] = "I_slope in component I (per_micromolar)" legend_constants[45] = "Canull in component I (micromolar)" legend_rates[0] = "d/dt Gi in component Gi (millimolar)" legend_rates[1] = "d/dt Ge in component Ge (millimolar)" legend_rates[3] = "d/dt G6P in component G6P (millimolar)" legend_rates[4] = "d/dt FBP in component FBP (micromolar)" legend_rates[5] = "d/dt ADP in component ADP (micromolar)" legend_rates[7] = "d/dt v in component membrane (millivolt)" legend_rates[8] = "d/dt n in component n (dimensionless)" legend_rates[6] = "d/dt Ca in component Ca (micromolar)" legend_rates[9] = "d/dt Caer in component Caer (micromolar)" legend_rates[2] = "d/dt I in component I (dimensionless)" return (legend_states, legend_algebraic, legend_voi, legend_constants) def initConsts(): constants = [0.0] * sizeConstants; states = [0.0] * sizeStates; states[0] = 0 states[1] = 7 constants[0] = 450000 constants[1] = 15 constants[2] = 1 constants[3] = 1 constants[4] = 5 states[2] = 0 states[3] = 200 constants[5] = 0.005 states[4] = 40 constants[6] = 7 constants[7] = 8 constants[8] = 7 constants[9] = 0.8 constants[10] = 4 constants[11] = 0.06 constants[12] = 2 constants[13] = 0.02 constants[14] = 0.2 constants[15] = 20 constants[16] = 20 constants[17] = 20 constants[18] = 30 constants[19] = 1 constants[20] = 50000 constants[21] = 1000 constants[22] = 3000 states[5] = 780 constants[23] = 300000 constants[24] = 0.5 constants[25] = 0.35 states[6] = 0.1 constants[26] = 2.2 constants[27] = 0.1 states[7] = -60 constants[28] = 5300 constants[29] = 2700 constants[30] = -75 states[8] = 0 constants[31] = 1000 constants[32] = 25 constants[33] = 400 constants[34] = 0.5 constants[35] = 40000 constants[36] = 0.01 states[9] = 185 constants[37] = 0.01 constants[38] = 31 constants[39] = 0.18 constants[40] = 4.5e-6 constants[41] = 0.4 constants[42] = 0.0002 constants[43] = 10000 constants[44] = 210 constants[45] = 0.055 constants[46] = 1.00000 return (states, constants) def computeRates(voi, states, constants): rates = [0.0] * sizeStates; algebraic = [0.0] * sizeAlgebraic algebraic[1] = constants[2]+(constants[1]-constants[2])/(1.00000+exp((states[2]-constants[4])/constants[3])) rates[1] = (algebraic[1]-states[1])/constants[0] algebraic[3] = custom_piecewise([greater_equal(states[6] , constants[45]), constants[44]*(states[6]-constants[45]) , less(states[6] , constants[45]), 0.00000 , True, float('nan')]) rates[2] = (algebraic[3]-states[2])/constants[43] algebraic[5] = 1.00000/(1.00000+exp(-(states[7]+16.0000)/5.60000)) algebraic[2] = 1.00000/(0.0350000*cosh((states[7]+16.0000)/22.4000)) rates[8] = (algebraic[5]-states[8])/algebraic[2] algebraic[4] = (constants[7]*(states[1]-states[0])*constants[6])/((constants[6]+states[1])*(constants[6]+states[0])) algebraic[6] = (constants[9]*(power(states[0], constants[10])))/(power(constants[8], constants[10])+power(states[0], constants[10])) rates[0] = algebraic[4]-algebraic[6] algebraic[13] = 1.00000/(1.00000+exp(-(states[7]+20.0000)/12.0000)) algebraic[14] = constants[31]*algebraic[13]*(states[7]-constants[32]) algebraic[16] = -(constants[40]*algebraic[14]+constants[39]*states[6]) algebraic[20] = constants[42]*(states[9]-states[6]) algebraic[18] = constants[41]*states[6] algebraic[22] = algebraic[20]-algebraic[18] rates[6] = constants[36]*(algebraic[16]+algebraic[22]) rates[9] = -constants[37]*constants[38]*algebraic[22] rootfind_0(voi, constants, rates, states, algebraic) algebraic[7] = 0.200000*(power(states[4]/1.00000, 1.0/2)) algebraic[11] = (constants[26]*algebraic[7])/(constants[27]+algebraic[7]) rates[5] = (1.00000/constants[23])*(algebraic[24]-states[5]*exp((constants[24]+algebraic[11])*(1.00000-states[6]/constants[25]))) algebraic[12] = constants[29]*states[8]*(states[7]-constants[30]) algebraic[15] = (constants[33]*(power(states[6], 2.00000)))/(power(constants[34], 2.00000)+power(states[6], 2.00000)) algebraic[17] = algebraic[15]*(states[7]-constants[30]) algebraic[19] = 0.165000*states[5] algebraic[21] = 0.135000*states[5] algebraic[26] = 0.00500000*algebraic[24] algebraic[28] = (0.0800000*(1.00000+(2.00000*algebraic[19])/17.0000)+0.890000*(power(algebraic[19]/17.0000, 2.00000)))/((power(1.00000+algebraic[19]/17.0000, 2.00000))*(1.00000+algebraic[21]/26.0000+algebraic[26]/1.00000)) algebraic[30] = constants[35]*algebraic[28] algebraic[32] = algebraic[30]*(states[7]-constants[30]) rates[7] = -(algebraic[12]+algebraic[14]+algebraic[17]+algebraic[32])/constants[28] algebraic[25] = power(algebraic[23]/constants[18], 1.00000) algebraic[8] = power(states[4]/constants[19], 1.00000) algebraic[0] = 0.300000*states[3] algebraic[9] = power((power(algebraic[0], 2.00000))/constants[20], 1.00000) algebraic[27] = power((power(algebraic[24], 2.00000))/constants[21], 1.00000) algebraic[29] = (power(algebraic[23]/constants[18], 1.00000))*(power(states[4]/constants[19], 1.00000)) algebraic[31] = (1.00000/(power(constants[13], 1.00000*1.00000)))*(power(algebraic[23]/constants[18], 1.00000))*(power((power(algebraic[0], 2.00000))/constants[20], 1.00000)) algebraic[33] = (1.00000/(power(constants[15], 1.00000*1.00000)))*(power(algebraic[23]/constants[18], 1.00000))*(power((power(algebraic[24], 2.00000))/constants[21], 1.00000)) algebraic[34] = (1.00000/(power(constants[16], 1.00000*1.00000)))*(power(states[4]/constants[19], 1.00000))*(power((power(algebraic[24], 2.00000))/constants[21], 1.00000)) algebraic[35] = (1.00000/(power(constants[17], 1.00000*1.00000)))*(power((power(algebraic[0], 2.00000))/constants[20], 1.00000))*(power((power(algebraic[24], 2.00000))/constants[21], 1.00000)) algebraic[10] = (1.00000/(power(constants[14], 1.00000*1.00000)))*(power(states[4]/constants[19], 1.00000))*(power((power(algebraic[0], 2.00000))/constants[20], 1.00000)) algebraic[36] = (1.00000/((power(constants[13], 1.00000*1.00000))*(power(constants[14], 1.00000*1.00000))))*(power(algebraic[23]/constants[18], 1.00000))*(power(states[4]/constants[19], 1.00000))*(power((power(algebraic[0], 2.00000))/constants[20], 1.00000)) algebraic[37] = (1.00000/((power(constants[14], 1.00000*1.00000))*(power(constants[16], 1.00000*1.00000))*(power(constants[17], 1.00000*1.00000))))*(power(states[4]/constants[19], 1.00000))*(power((power(algebraic[0], 2.00000))/constants[20], 1.00000))*(power((power(algebraic[24], 2.00000))/constants[21], 1.00000)) algebraic[38] = (1.00000/((power(constants[13], 1.00000*1.00000))*(power(constants[15], 1.00000*1.00000))*(power(constants[17], 1.00000*1.00000))))*(power(algebraic[23]/constants[18], 1.00000))*(power((power(algebraic[0], 2.00000))/constants[20], 1.00000))*(power((power(algebraic[24], 2.00000))/constants[21], 1.00000)) algebraic[39] = (1.00000/((power(constants[15], 1.00000*1.00000))*(power(constants[16], 1.00000*1.00000))))*(power(algebraic[23]/constants[18], 1.00000))*(power(states[4]/constants[19], 1.00000))*(power((power(algebraic[24], 2.00000))/constants[21], 1.00000)) algebraic[40] = (1.00000/((power(constants[13], 1.00000*1.00000))*(power(constants[14], 1.00000*1.00000))*(power(constants[15], 1.00000*1.00000))*(power(constants[16], 1.00000*1.00000))*(power(constants[17], 1.00000*1.00000))))*(power(algebraic[23]/constants[18], 1.00000))*(power(states[4]/constants[19], 1.00000))*(power((power(algebraic[0], 2.00000))/constants[20], 1.00000))*(power((power(algebraic[24], 2.00000))/constants[21], 1.00000)) algebraic[41] = (constants[12]*((1.00000-constants[11])*algebraic[36]+constants[11]*(algebraic[9]+algebraic[31]+algebraic[35]+algebraic[36]+algebraic[37]+algebraic[38]+algebraic[10]+algebraic[40])))/(constants[46]+algebraic[25]+algebraic[8]+algebraic[9]+algebraic[27]+algebraic[29]+algebraic[31]+algebraic[33]+algebraic[34]+algebraic[35]+algebraic[10]+algebraic[36]+algebraic[37]+algebraic[38]+algebraic[39]+algebraic[40]) rates[3] = constants[5]*(algebraic[6]-algebraic[41]) rates[4] = constants[5]*(algebraic[41]-0.500000*algebraic[7]) return(rates) def computeAlgebraic(constants, states, voi): algebraic = array([[0.0] * len(voi)] * sizeAlgebraic) states = array(states) voi = array(voi) algebraic[1] = constants[2]+(constants[1]-constants[2])/(1.00000+exp((states[2]-constants[4])/constants[3])) algebraic[3] = custom_piecewise([greater_equal(states[6] , constants[45]), constants[44]*(states[6]-constants[45]) , less(states[6] , constants[45]), 0.00000 , True, float('nan')]) algebraic[5] = 1.00000/(1.00000+exp(-(states[7]+16.0000)/5.60000)) algebraic[2] = 1.00000/(0.0350000*cosh((states[7]+16.0000)/22.4000)) algebraic[4] = (constants[7]*(states[1]-states[0])*constants[6])/((constants[6]+states[1])*(constants[6]+states[0])) algebraic[6] = (constants[9]*(power(states[0], constants[10])))/(power(constants[8], constants[10])+power(states[0], constants[10])) algebraic[13] = 1.00000/(1.00000+exp(-(states[7]+20.0000)/12.0000)) algebraic[14] = constants[31]*algebraic[13]*(states[7]-constants[32]) algebraic[16] = -(constants[40]*algebraic[14]+constants[39]*states[6]) algebraic[20] = constants[42]*(states[9]-states[6]) algebraic[18] = constants[41]*states[6] algebraic[22] = algebraic[20]-algebraic[18] algebraic[7] = 0.200000*(power(states[4]/1.00000, 1.0/2)) algebraic[11] = (constants[26]*algebraic[7])/(constants[27]+algebraic[7]) algebraic[12] = constants[29]*states[8]*(states[7]-constants[30]) algebraic[15] = (constants[33]*(power(states[6], 2.00000)))/(power(constants[34], 2.00000)+power(states[6], 2.00000)) algebraic[17] = algebraic[15]*(states[7]-constants[30]) algebraic[19] = 0.165000*states[5] algebraic[21] = 0.135000*states[5] algebraic[26] = 0.00500000*algebraic[24] algebraic[28] = (0.0800000*(1.00000+(2.00000*algebraic[19])/17.0000)+0.890000*(power(algebraic[19]/17.0000, 2.00000)))/((power(1.00000+algebraic[19]/17.0000, 2.00000))*(1.00000+algebraic[21]/26.0000+algebraic[26]/1.00000)) algebraic[30] = constants[35]*algebraic[28] algebraic[32] = algebraic[30]*(states[7]-constants[30]) algebraic[25] = power(algebraic[23]/constants[18], 1.00000) algebraic[8] = power(states[4]/constants[19], 1.00000) algebraic[0] = 0.300000*states[3] algebraic[9] = power((power(algebraic[0], 2.00000))/constants[20], 1.00000) algebraic[27] = power((power(algebraic[24], 2.00000))/constants[21], 1.00000) algebraic[29] = (power(algebraic[23]/constants[18], 1.00000))*(power(states[4]/constants[19], 1.00000)) algebraic[31] = (1.00000/(power(constants[13], 1.00000*1.00000)))*(power(algebraic[23]/constants[18], 1.00000))*(power((power(algebraic[0], 2.00000))/constants[20], 1.00000)) algebraic[33] = (1.00000/(power(constants[15], 1.00000*1.00000)))*(power(algebraic[23]/constants[18], 1.00000))*(power((power(algebraic[24], 2.00000))/constants[21], 1.00000)) algebraic[34] = (1.00000/(power(constants[16], 1.00000*1.00000)))*(power(states[4]/constants[19], 1.00000))*(power((power(algebraic[24], 2.00000))/constants[21], 1.00000)) algebraic[35] = (1.00000/(power(constants[17], 1.00000*1.00000)))*(power((power(algebraic[0], 2.00000))/constants[20], 1.00000))*(power((power(algebraic[24], 2.00000))/constants[21], 1.00000)) algebraic[10] = (1.00000/(power(constants[14], 1.00000*1.00000)))*(power(states[4]/constants[19], 1.00000))*(power((power(algebraic[0], 2.00000))/constants[20], 1.00000)) algebraic[36] = (1.00000/((power(constants[13], 1.00000*1.00000))*(power(constants[14], 1.00000*1.00000))))*(power(algebraic[23]/constants[18], 1.00000))*(power(states[4]/constants[19], 1.00000))*(power((power(algebraic[0], 2.00000))/constants[20], 1.00000)) algebraic[37] = (1.00000/((power(constants[14], 1.00000*1.00000))*(power(constants[16], 1.00000*1.00000))*(power(constants[17], 1.00000*1.00000))))*(power(states[4]/constants[19], 1.00000))*(power((power(algebraic[0], 2.00000))/constants[20], 1.00000))*(power((power(algebraic[24], 2.00000))/constants[21], 1.00000)) algebraic[38] = (1.00000/((power(constants[13], 1.00000*1.00000))*(power(constants[15], 1.00000*1.00000))*(power(constants[17], 1.00000*1.00000))))*(power(algebraic[23]/constants[18], 1.00000))*(power((power(algebraic[0], 2.00000))/constants[20], 1.00000))*(power((power(algebraic[24], 2.00000))/constants[21], 1.00000)) algebraic[39] = (1.00000/((power(constants[15], 1.00000*1.00000))*(power(constants[16], 1.00000*1.00000))))*(power(algebraic[23]/constants[18], 1.00000))*(power(states[4]/constants[19], 1.00000))*(power((power(algebraic[24], 2.00000))/constants[21], 1.00000)) algebraic[40] = (1.00000/((power(constants[13], 1.00000*1.00000))*(power(constants[14], 1.00000*1.00000))*(power(constants[15], 1.00000*1.00000))*(power(constants[16], 1.00000*1.00000))*(power(constants[17], 1.00000*1.00000))))*(power(algebraic[23]/constants[18], 1.00000))*(power(states[4]/constants[19], 1.00000))*(power((power(algebraic[0], 2.00000))/constants[20], 1.00000))*(power((power(algebraic[24], 2.00000))/constants[21], 1.00000)) algebraic[41] = (constants[12]*((1.00000-constants[11])*algebraic[36]+constants[11]*(algebraic[9]+algebraic[31]+algebraic[35]+algebraic[36]+algebraic[37]+algebraic[38]+algebraic[10]+algebraic[40])))/(constants[46]+algebraic[25]+algebraic[8]+algebraic[9]+algebraic[27]+algebraic[29]+algebraic[31]+algebraic[33]+algebraic[34]+algebraic[35]+algebraic[10]+algebraic[36]+algebraic[37]+algebraic[38]+algebraic[39]+algebraic[40]) return algebraic initialGuess0 = None def rootfind_0(voi, constants, rates, states, algebraic): """Calculate values of algebraic variables for DAE""" from scipy.optimize import fsolve global initialGuess0 if initialGuess0 is None: initialGuess0 = ones(2)*0.1 if not iterable(voi): soln = fsolve(residualSN_0, initialGuess0, args=(algebraic, voi, constants, rates, states), xtol=1E-6) initialGuess0 = soln algebraic[23] = soln[0] algebraic[24] = soln[1] else: for (i,t) in enumerate(voi): soln = fsolve(residualSN_0, initialGuess0, args=(algebraic[:,i], voi[i], constants, rates[:i], states[:,i]), xtol=1E-6) initialGuess0 = soln algebraic[23][i] = soln[0] algebraic[24][i] = soln[1] def residualSN_0(algebraicCandidate, algebraic, voi, constants, rates, states): resid = array([0.0] * 2) algebraic[23] = algebraicCandidate[0] algebraic[24] = algebraicCandidate[1] resid[0] = (algebraic[24]-(constants[22]-(states[5]+algebraic[23]))) resid[1] = (algebraic[23]-(power(states[5], 2.00000))/algebraic[24]) return resid def custom_piecewise(cases): """Compute result of a piecewise function""" return select(cases[0::2],cases[1::2]) def solve_model(): """Solve model with ODE solver""" from scipy.integrate import ode # Initialise constants and state variables (init_states, constants) = initConsts() # Set timespan to solve over voi = linspace(0, 10, 500) # Construct ODE object to solve r = ode(computeRates) r.set_integrator('vode', method='bdf', atol=1e-06, rtol=1e-06, max_step=1) r.set_initial_value(init_states, voi[0]) r.set_f_params(constants) # Solve model states = array([[0.0] * len(voi)] * sizeStates) states[:,0] = init_states for (i,t) in enumerate(voi[1:]): if r.successful(): r.integrate(t) states[:,i+1] = r.y else: break # Compute algebraic variables algebraic = computeAlgebraic(constants, states, voi) return (voi, states, algebraic) def plot_model(voi, states, algebraic): """Plot variables against variable of integration""" import pylab (legend_states, legend_algebraic, legend_voi, legend_constants) = createLegends() pylab.figure(1) pylab.plot(voi,vstack((states,algebraic)).T) pylab.xlabel(legend_voi) pylab.legend(legend_states + legend_algebraic, loc='best') pylab.show() if __name__ == "__main__": (voi, states, algebraic) = solve_model() plot_model(voi, states, algebraic)