/* There are a total of 21 entries in the algebraic variable array. There are a total of 21 entries in each of the rate and state variable arrays. There are a total of 116 entries in the constant variable array. */ /* * VOI is time in component environment (minute). * STATES[0] is GLY in component GLY (millimolar). * ALGEBRAIC[18] is flux_GP in component flux_GP (flux). * STATES[1] is G1P in component G1P (millimolar). * ALGEBRAIC[3] is V_PGLM in component V_PGLM (flux). * STATES[2] is G6P in component G6P (millimolar). * ALGEBRAIC[4] is V_PGI in component V_PGI (flux). * STATES[3] is F6P in component F6P (millimolar). * ALGEBRAIC[19] is V_PFK in component V_PFK (flux). * STATES[4] is FBP in component FBP (millimolar). * ALGEBRAIC[8] is V_ALD in component V_ALD (flux). * STATES[5] is DHAP in component DHAP (millimolar). * ALGEBRAIC[9] is V_TPI in component V_TPI (flux). * STATES[6] is GAP in component GAP (millimolar). * ALGEBRAIC[20] is V_GAPDH in component V_GAPDH (flux). * STATES[7] is Thirteen_BPG in component Thirteen_BPG (millimolar). * ALGEBRAIC[11] is V_PGK in component V_PGK (flux). * STATES[8] is three_PG in component three_PG (millimolar). * ALGEBRAIC[12] is V_PGM in component V_PGM (flux). * STATES[9] is two_PG in component two_PG (millimolar). * ALGEBRAIC[13] is V_ENOL in component V_ENOL (flux). * STATES[10] is PEP in component PEP (millimolar). * ALGEBRAIC[14] is V_PK in component V_PK (flux). * STATES[11] is PYR in component PYR (millimolar). * ALGEBRAIC[15] is V_LDH in component V_LDH (flux). * STATES[12] is LAC in component LAC (millimolar). * ALGEBRAIC[0] is output in component LAC (flux). * STATES[13] is Pi in component Pi (millimolar). * CONSTANTS[0] is V_ATPase in component V_ATPase (flux). * STATES[14] is ADP in component ADP (millimolar). * ALGEBRAIC[17] is V_ADK in component V_ADK (flux). * ALGEBRAIC[16] is V_CK in component V_CK (flux). * STATES[15] is ATP in component ATP (millimolar). * STATES[16] is AMP in component AMP (millimolar). * STATES[17] is PCr in component PCr (millimolar). * STATES[18] is Cr in component Cr (millimolar). * STATES[19] is NADH in component NADH (millimolar). * STATES[20] is NAD in component NAD (millimolar). * CONSTANTS[1] is frac_a in component flux_GP (dimensionless). * CONSTANTS[2] is frac_b in component flux_GP (dimensionless). * ALGEBRAIC[1] is V_GPa in component V_GPa (flux). * ALGEBRAIC[2] is V_GPb in component V_GPb (flux). * CONSTANTS[3] is Ki_GLY_f in component V_GPa (millimolar). * CONSTANTS[4] is Ki_GLY_b in component V_GPa (millimolar). * CONSTANTS[5] is K_GLY_f in component V_GPa (millimolar). * CONSTANTS[6] is K_GLY_b in component V_GPa (millimolar). * CONSTANTS[7] is Keq_GP in component V_GPa (dimensionless). * CONSTANTS[8] is Ki_Pi in component V_GPa (millimolar). * CONSTANTS[9] is K_Pi in component V_GPa (millimolar). * CONSTANTS[10] is Ki_G1P in component V_GPa (millimolar). * CONSTANTS[100] is V_max_r in component V_GPa (flux). * CONSTANTS[11] is V_max_f in component V_GPa (flux). * CONSTANTS[12] is Ki_GLY_f in component V_GPb (millimolar). * CONSTANTS[13] is Ki_GLY_b in component V_GPb (millimolar). * CONSTANTS[14] is K_GLY_f in component V_GPb (millimolar). * CONSTANTS[15] is Keq_GP in component V_GPb (dimensionless). * CONSTANTS[16] is nH in component V_GPb (dimensionless). * CONSTANTS[17] is K_AMP in component V_GPb (millimolar_1_75). * CONSTANTS[18] is K_GLY_b in component V_GPb (millimolar). * CONSTANTS[19] is Ki_Pi in component V_GPb (millimolar). * CONSTANTS[20] is K_Pi in component V_GPb (millimolar). * CONSTANTS[21] is Ki_G1P in component V_GPb (millimolar). * CONSTANTS[22] is K_G1P in component V_GPb (millimolar). * CONSTANTS[101] is V_max_r in component V_GPb (flux). * CONSTANTS[23] is V_max_f in component V_GPb (flux). * CONSTANTS[24] is K_G1P in component V_PGLM (millimolar). * CONSTANTS[25] is K_G6P in component V_PGLM (millimolar). * CONSTANTS[26] is Keq_PGLM in component V_PGLM (dimensionless). * CONSTANTS[102] is V_max_r in component V_PGLM (flux). * CONSTANTS[27] is V_max_f in component V_PGLM (flux). * CONSTANTS[28] is K_G6P in component V_PGI (millimolar). * CONSTANTS[29] is K_F6P in component V_PGI (millimolar). * CONSTANTS[30] is Keq_PGI in component V_PGI (dimensionless). * CONSTANTS[31] is V_max_r in component V_PGI (flux). * CONSTANTS[103] is V_max_f in component V_PGI (flux). * CONSTANTS[32] is K_FBP in component V_PFK (millimolar). * CONSTANTS[33] is K_FBP_ in component V_PFK (millimolar). * CONSTANTS[34] is K_F6P in component V_PFK (millimolar). * CONSTANTS[35] is K_ATP in component V_PFK (millimolar). * CONSTANTS[36] is K_F6P_ in component V_PFK (millimolar). * CONSTANTS[37] is K_ATP_ in component V_PFK (millimolar). * CONSTANTS[38] is K_ADP in component V_PFK (millimolar). * CONSTANTS[39] is K_ADP_ in component V_PFK (millimolar). * CONSTANTS[40] is Ki_ATP in component V_PFK (millimolar). * CONSTANTS[41] is Ka_AMP in component V_PFK (millimolar). * CONSTANTS[104] is V_max_r in component V_PFK (flux). * CONSTANTS[42] is V_max_f in component V_PFK (flux). * CONSTANTS[105] is alpha in component V_PFK (dimensionless). * ALGEBRAIC[7] is L in component V_PFK (dimensionless). * CONSTANTS[43] is Lo in component V_PFK (dimensionless). * ALGEBRAIC[5] is delta in component V_PFK (dimensionless). * ALGEBRAIC[6] is delta_ in component V_PFK (dimensionless). * CONSTANTS[44] is d in component V_PFK (dimensionless). * CONSTANTS[45] is var_e in component V_PFK (dimensionless). * CONSTANTS[46] is K_GAP in component V_ALD (millimolar). * CONSTANTS[47] is K_FBP in component V_ALD (millimolar). * CONSTANTS[48] is K_DHAP in component V_ALD (millimolar). * CONSTANTS[49] is Keq_ALD in component V_ALD (millimolar). * CONSTANTS[106] is V_max_r in component V_ALD (flux). * CONSTANTS[50] is V_max_f in component V_ALD (flux). * CONSTANTS[51] is K_GAP in component V_TPI (millimolar). * CONSTANTS[52] is K_DHAP in component V_TPI (millimolar). * CONSTANTS[53] is Keq_TPI in component V_TPI (dimensionless). * CONSTANTS[107] is V_max_r in component V_TPI (flux). * CONSTANTS[54] is V_max_f in component V_TPI (flux). * ALGEBRAIC[10] is D_GAPDH in component V_GAPDH (dimensionless). * CONSTANTS[55] is K_GAP in component V_GAPDH (millimolar). * CONSTANTS[56] is K_Pi in component V_GAPDH (millimolar). * CONSTANTS[57] is K_NAD in component V_GAPDH (millimolar). * CONSTANTS[58] is K_NADH in component V_GAPDH (millimolar). * CONSTANTS[59] is K_Thirteen_BPG in component V_GAPDH (millimolar). * CONSTANTS[60] is Keq_GAPDH in component V_GAPDH (dimensionless). * CONSTANTS[108] is V_max_r in component V_GAPDH (flux). * CONSTANTS[61] is V_max_f in component V_GAPDH (flux). * CONSTANTS[62] is K_three_PG in component V_PGK (millimolar). * CONSTANTS[63] is K_ADP in component V_PGK (millimolar). * CONSTANTS[64] is K_ATP in component V_PGK (millimolar). * CONSTANTS[65] is K_Thirteen_BPG in component V_PGK (millimolar). * CONSTANTS[66] is Keq_PGK in component V_PGK (dimensionless). * CONSTANTS[67] is V_max_r in component V_PGK (flux). * CONSTANTS[109] is V_max_f in component V_PGK (flux). * CONSTANTS[68] is K_two_PG in component V_PGM (millimolar). * CONSTANTS[69] is K_three_PG in component V_PGM (millimolar). * CONSTANTS[70] is Keq_PGM in component V_PGM (dimensionless). * CONSTANTS[110] is V_max_r in component V_PGM (flux). * CONSTANTS[71] is V_max_f in component V_PGM (flux). * CONSTANTS[72] is K_PEP in component V_ENOL (millimolar). * CONSTANTS[73] is K_two_PG in component V_ENOL (millimolar). * CONSTANTS[74] is Keq_ENOL in component V_ENOL (dimensionless). * CONSTANTS[111] is V_max_r in component V_ENOL (flux). * CONSTANTS[75] is V_max_f in component V_ENOL (flux). * CONSTANTS[76] is K_PYR in component V_PK (millimolar). * CONSTANTS[77] is K_ADP in component V_PK (millimolar). * CONSTANTS[78] is K_ATP in component V_PK (millimolar). * CONSTANTS[79] is K_PEP in component V_PK (millimolar). * CONSTANTS[80] is Keq_PK in component V_PK (dimensionless). * CONSTANTS[112] is V_max_r in component V_PK (flux). * CONSTANTS[81] is V_max_f in component V_PK (flux). * CONSTANTS[82] is K_LAC in component V_LDH (millimolar). * CONSTANTS[83] is K_NADH in component V_LDH (millimolar). * CONSTANTS[84] is K_NAD in component V_LDH (millimolar). * CONSTANTS[85] is K_PYR in component V_LDH (millimolar). * CONSTANTS[86] is Keq_LDH in component V_LDH (dimensionless). * CONSTANTS[113] is V_max_r in component V_LDH (flux). * CONSTANTS[87] is V_max_f in component V_LDH (flux). * CONSTANTS[88] is Ki_ADP in component V_CK (millimolar). * CONSTANTS[89] is K_Cr in component V_CK (millimolar). * CONSTANTS[90] is K_PCr in component V_CK (millimolar). * CONSTANTS[91] is Ki_PCr in component V_CK (millimolar). * CONSTANTS[92] is Ki_ATP in component V_CK (millimolar). * CONSTANTS[93] is Keq_CK in component V_CK (dimensionless). * CONSTANTS[94] is V_max_r in component V_CK (flux). * CONSTANTS[114] is V_max_f in component V_CK (flux). * CONSTANTS[95] is K_ADP in component V_ADK (millimolar). * CONSTANTS[96] is K_AMP in component V_ADK (millimolar). * CONSTANTS[97] is K_ATP in component V_ADK (millimolar). * CONSTANTS[98] is Keq_ADK in component V_ADK (dimensionless). * CONSTANTS[115] is V_max_r in component V_ADK (flux). * CONSTANTS[99] is V_max_f in component V_ADK (flux). * RATES[0] is d/dt GLY in component GLY (millimolar). * RATES[1] is d/dt G1P in component G1P (millimolar). * RATES[2] is d/dt G6P in component G6P (millimolar). * RATES[3] is d/dt F6P in component F6P (millimolar). * RATES[4] is d/dt FBP in component FBP (millimolar). * RATES[5] is d/dt DHAP in component DHAP (millimolar). * RATES[6] is d/dt GAP in component GAP (millimolar). * RATES[7] is d/dt Thirteen_BPG in component Thirteen_BPG (millimolar). * RATES[8] is d/dt three_PG in component three_PG (millimolar). * RATES[9] is d/dt two_PG in component two_PG (millimolar). * RATES[10] is d/dt PEP in component PEP (millimolar). * RATES[11] is d/dt PYR in component PYR (millimolar). * RATES[12] is d/dt LAC in component LAC (millimolar). * RATES[13] is d/dt Pi in component Pi (millimolar). * RATES[14] is d/dt ADP in component ADP (millimolar). * RATES[15] is d/dt ATP in component ATP (millimolar). * RATES[16] is d/dt AMP in component AMP (millimolar). * RATES[17] is d/dt PCr in component PCr (millimolar). * RATES[18] is d/dt Cr in component Cr (millimolar). * RATES[19] is d/dt NADH in component NADH (millimolar). * RATES[20] is d/dt NAD in component NAD (millimolar). * There are a total of 0 condition variables. */ void initConsts(double* CONSTANTS, double* RATES, double *STATES) { STATES[0] = 112.0; STATES[1] = 0.0589; STATES[2] = 0.75; STATES[3] = 0.228; STATES[4] = 0.0723; STATES[5] = 0.0764; STATES[6] = 0.0355; STATES[7] = 0.065; STATES[8] = 0.052; STATES[9] = 0.005; STATES[10] = 0.0194; STATES[11] = 0.0994; STATES[12] = 1.3; STATES[13] = 4.1; CONSTANTS[0] = 600.0; STATES[14] = 0.013; STATES[15] = 8.2; STATES[16] = 0.99; STATES[17] = 34.67; STATES[18] = 35.0; STATES[19] = 0.001; STATES[20] = 0.5; CONSTANTS[1] = 0.4; CONSTANTS[2] = 0.6; CONSTANTS[3] = 2.0; CONSTANTS[4] = 2.0; CONSTANTS[5] = 1.7; CONSTANTS[6] = 0.15; CONSTANTS[7] = 0.42; CONSTANTS[8] = 4.7; CONSTANTS[9] = 4.0; CONSTANTS[10] = 10.1; CONSTANTS[11] = 20.0; CONSTANTS[12] = 15.0; CONSTANTS[13] = 4.4; CONSTANTS[14] = 1.7; CONSTANTS[15] = 0.42; CONSTANTS[16] = 1.75; CONSTANTS[17] = 1.9E-6; CONSTANTS[18] = 0.15; CONSTANTS[19] = 4.6; CONSTANTS[20] = 0.2; CONSTANTS[21] = 7.4; CONSTANTS[22] = 1.5; CONSTANTS[23] = 30.0; CONSTANTS[24] = 0.063; CONSTANTS[25] = 0.03; CONSTANTS[26] = 16.62; CONSTANTS[27] = 480.0; CONSTANTS[28] = 0.18; CONSTANTS[29] = 0.119; CONSTANTS[30] = 0.45; CONSTANTS[31] = 880.0; CONSTANTS[32] = 4.02; CONSTANTS[33] = 4.02; CONSTANTS[34] = 0.18; CONSTANTS[35] = 0.08; CONSTANTS[36] = 20.0; CONSTANTS[37] = 0.25; CONSTANTS[38] = 2.7; CONSTANTS[39] = 2.7; CONSTANTS[40] = 0.87; CONSTANTS[41] = 0.06; CONSTANTS[42] = 56.0; CONSTANTS[43] = 13.0; CONSTANTS[44] = 0.01; CONSTANTS[45] = 0.01; CONSTANTS[46] = 1.0; CONSTANTS[47] = 0.05; CONSTANTS[48] = 2.0; CONSTANTS[49] = 9.5E-5; CONSTANTS[50] = 104.0; CONSTANTS[51] = 0.32; CONSTANTS[52] = 0.61; CONSTANTS[53] = 0.052; CONSTANTS[54] = 12000.0; CONSTANTS[55] = 0.0025; CONSTANTS[56] = 0.29; CONSTANTS[57] = 0.09; CONSTANTS[58] = 0.0033; CONSTANTS[59] = 0.0008; CONSTANTS[60] = 0.089; CONSTANTS[61] = 1265.0; CONSTANTS[62] = 1.2; CONSTANTS[63] = 0.008; CONSTANTS[64] = 0.35; CONSTANTS[65] = 0.002; CONSTANTS[66] = 57109.0; CONSTANTS[67] = 1120.0; CONSTANTS[68] = 0.014; CONSTANTS[69] = 0.2; CONSTANTS[70] = 0.18; CONSTANTS[71] = 1120.0; CONSTANTS[72] = 0.37; CONSTANTS[73] = 0.1; CONSTANTS[74] = 0.49; CONSTANTS[75] = 192.0; CONSTANTS[76] = 7.05; CONSTANTS[77] = 0.3; CONSTANTS[78] = 1.13; CONSTANTS[79] = 0.08; CONSTANTS[80] = 10304.0; CONSTANTS[81] = 1440.0; CONSTANTS[82] = 17.0; CONSTANTS[83] = 0.002; CONSTANTS[84] = 0.849; CONSTANTS[85] = 0.335; CONSTANTS[86] = 16198.0; CONSTANTS[87] = 1920.0; CONSTANTS[88] = 0.135; CONSTANTS[89] = 3.8; CONSTANTS[90] = 1.11; CONSTANTS[91] = 3.9; CONSTANTS[92] = 3.5; CONSTANTS[93] = 233.0; CONSTANTS[94] = 500.0; CONSTANTS[95] = 0.35; CONSTANTS[96] = 0.32; CONSTANTS[97] = 0.27; CONSTANTS[98] = 2.21; CONSTANTS[99] = 880.0; CONSTANTS[100] = ( CONSTANTS[11]*CONSTANTS[6]*CONSTANTS[10])/( CONSTANTS[3]*CONSTANTS[9]*CONSTANTS[7]); CONSTANTS[101] = ( CONSTANTS[23]*CONSTANTS[13]*CONSTANTS[22])/( CONSTANTS[14]*CONSTANTS[19]*CONSTANTS[15]); CONSTANTS[102] = ( CONSTANTS[27]*CONSTANTS[25])/( CONSTANTS[24]*CONSTANTS[26]); CONSTANTS[103] = ( CONSTANTS[31]*CONSTANTS[28]*CONSTANTS[30])/CONSTANTS[29]; CONSTANTS[104] = ( CONSTANTS[42]*CONSTANTS[38]*CONSTANTS[32])/( CONSTANTS[35]*CONSTANTS[34]); CONSTANTS[105] = ( CONSTANTS[34]*CONSTANTS[35])/( CONSTANTS[36]*CONSTANTS[37]); CONSTANTS[106] = ( CONSTANTS[50]*CONSTANTS[48]*CONSTANTS[46])/( CONSTANTS[47]*CONSTANTS[49]); CONSTANTS[107] = ( CONSTANTS[54]*CONSTANTS[52])/( CONSTANTS[51]*CONSTANTS[53]); CONSTANTS[108] = ( CONSTANTS[61]*1.00000*CONSTANTS[59]*CONSTANTS[58])/( CONSTANTS[55]*CONSTANTS[57]*CONSTANTS[56]*CONSTANTS[60]); CONSTANTS[109] = ( CONSTANTS[67]*CONSTANTS[65]*CONSTANTS[63]*CONSTANTS[66])/( CONSTANTS[62]*CONSTANTS[64]); CONSTANTS[110] = ( CONSTANTS[71]*CONSTANTS[68])/( CONSTANTS[69]*CONSTANTS[70]); CONSTANTS[111] = ( CONSTANTS[75]*CONSTANTS[72])/( CONSTANTS[73]*CONSTANTS[74]); CONSTANTS[112] = ( CONSTANTS[81]*CONSTANTS[78]*CONSTANTS[76])/( CONSTANTS[79]*CONSTANTS[77]*CONSTANTS[80]); CONSTANTS[113] = ( CONSTANTS[87]*CONSTANTS[82]*CONSTANTS[84])/( CONSTANTS[85]*CONSTANTS[83]*CONSTANTS[86]); CONSTANTS[114] = ( CONSTANTS[94]*CONSTANTS[92]*CONSTANTS[89]*CONSTANTS[93])/( CONSTANTS[88]*CONSTANTS[90]); CONSTANTS[115] = ( CONSTANTS[99]*pow(CONSTANTS[95], 2.00000))/( CONSTANTS[97]*CONSTANTS[96]*CONSTANTS[98]); RATES[0] = 0.1001; RATES[1] = 0.1001; RATES[2] = 0.1001; RATES[3] = 0.1001; RATES[4] = 0.1001; RATES[5] = 0.1001; RATES[6] = 0.1001; RATES[7] = 0.1001; RATES[8] = 0.1001; RATES[9] = 0.1001; RATES[10] = 0.1001; RATES[11] = 0.1001; RATES[12] = 0.1001; RATES[13] = 0.1001; RATES[14] = 0.1001; RATES[15] = 0.1001; RATES[16] = 0.1001; RATES[17] = 0.1001; RATES[18] = 0.1001; RATES[19] = 0.1001; RATES[20] = 0.1001; } void computeResiduals(double VOI, double* CONSTANTS, double* RATES, double* OLDRATES, double* STATES, double* OLDSTATES, double* ALGEBRAIC, double* CONDVARS) { resid[0] = RATES[0] - - ALGEBRAIC[18]; resid[1] = RATES[1] - ALGEBRAIC[18] - ALGEBRAIC[3]; resid[2] = RATES[2] - ALGEBRAIC[3] - ALGEBRAIC[4]; resid[3] = RATES[3] - ALGEBRAIC[4] - ALGEBRAIC[19]; resid[4] = RATES[4] - ALGEBRAIC[19] - ALGEBRAIC[8]; resid[5] = RATES[5] - ALGEBRAIC[8]+ALGEBRAIC[9]; resid[6] = RATES[6] - ALGEBRAIC[8] - (ALGEBRAIC[9]+ALGEBRAIC[20]); resid[7] = RATES[7] - ALGEBRAIC[20] - ALGEBRAIC[11]; resid[8] = RATES[8] - ALGEBRAIC[11] - ALGEBRAIC[12]; resid[9] = RATES[9] - ALGEBRAIC[12] - ALGEBRAIC[13]; resid[10] = RATES[10] - ALGEBRAIC[13] - ALGEBRAIC[14]; resid[11] = RATES[11] - ALGEBRAIC[14] - ALGEBRAIC[15]; resid[12] = RATES[12] - ALGEBRAIC[15] - ALGEBRAIC[0]; resid[13] = RATES[13] - CONSTANTS[0] - (ALGEBRAIC[18]+ALGEBRAIC[20]); resid[14] = RATES[14] - ALGEBRAIC[19]+ 2.00000*ALGEBRAIC[17]+ALGEBRAIC[16]+CONSTANTS[0]+- (ALGEBRAIC[11]+ALGEBRAIC[14]); resid[15] = RATES[15] - ALGEBRAIC[11]+ALGEBRAIC[14]+- (ALGEBRAIC[19]+ALGEBRAIC[17]+ALGEBRAIC[16]+CONSTANTS[0]); resid[16] = RATES[16] - - ALGEBRAIC[17]; resid[17] = RATES[17] - ALGEBRAIC[16]; resid[18] = RATES[18] - - ALGEBRAIC[16]; resid[19] = RATES[19] - ALGEBRAIC[20] - ALGEBRAIC[15]; resid[20] = RATES[20] - ALGEBRAIC[15] - ALGEBRAIC[20]; } void computeVariables(double VOI, double* CONSTANTS, double* RATES, double* STATES, double* ALGEBRAIC) { } void computeEssentialVariables(double VOI, double* CONSTANTS, double* RATES, double* STATES, double* ALGEBRAIC) { ALGEBRAIC[0] = 0.200000*STATES[12]; ALGEBRAIC[3] = ( CONSTANTS[27]*(STATES[1]/CONSTANTS[24]) - CONSTANTS[102]*(STATES[2]/CONSTANTS[25]))/(1.00000+STATES[1]/CONSTANTS[24]+STATES[2]/CONSTANTS[25]); ALGEBRAIC[4] = ( CONSTANTS[103]*(STATES[2]/CONSTANTS[28]) - CONSTANTS[31]*(STATES[3]/CONSTANTS[29]))/(1.00000+STATES[2]/CONSTANTS[28]+STATES[3]/CONSTANTS[29]); ALGEBRAIC[8] = ( CONSTANTS[50]*(STATES[4]/CONSTANTS[47]) - CONSTANTS[106]*(( STATES[5]*STATES[6])/( CONSTANTS[48]*CONSTANTS[46])))/(1.00000+STATES[4]/CONSTANTS[47]+STATES[5]/CONSTANTS[48]+STATES[6]/CONSTANTS[46]); ALGEBRAIC[9] = ( CONSTANTS[54]*(STATES[6]/CONSTANTS[51]) - CONSTANTS[107]*(STATES[5]/CONSTANTS[52]))/(1.00000+STATES[5]/CONSTANTS[52]+STATES[6]/CONSTANTS[51]); ALGEBRAIC[11] = ( CONSTANTS[109]*(( STATES[7]*STATES[14])/( CONSTANTS[65]*CONSTANTS[63])) - CONSTANTS[67]*(( STATES[8]*STATES[15])/( CONSTANTS[62]*CONSTANTS[64])))/(1.00000+STATES[7]/CONSTANTS[65]+STATES[14]/CONSTANTS[63]+( STATES[7]*STATES[14])/( CONSTANTS[65]*CONSTANTS[63])+STATES[8]/CONSTANTS[62]+STATES[15]/CONSTANTS[64]+( STATES[8]*STATES[15])/( CONSTANTS[62]*CONSTANTS[64])); ALGEBRAIC[12] = ( CONSTANTS[71]*(STATES[8]/CONSTANTS[69]) - CONSTANTS[110]*(STATES[9]/CONSTANTS[68]))/(1.00000+STATES[8]/CONSTANTS[69]+STATES[9]/CONSTANTS[68]); ALGEBRAIC[13] = ( CONSTANTS[75]*(STATES[9]/CONSTANTS[73]) - CONSTANTS[111]*(STATES[10]/CONSTANTS[72]))/(1.00000+STATES[9]/CONSTANTS[73]+STATES[10]/CONSTANTS[72]); ALGEBRAIC[14] = ( CONSTANTS[81]*(( STATES[10]*STATES[14])/( CONSTANTS[79]*CONSTANTS[77])) - CONSTANTS[112]*(( STATES[11]*STATES[15])/( CONSTANTS[76]*CONSTANTS[78])))/(1.00000+STATES[10]/CONSTANTS[79]+STATES[14]/CONSTANTS[77]+( STATES[10]*STATES[14])/( CONSTANTS[79]*CONSTANTS[77])+STATES[11]/CONSTANTS[76]+STATES[15]/CONSTANTS[78]+( STATES[11]*STATES[15])/( CONSTANTS[76]*CONSTANTS[78])); ALGEBRAIC[15] = ( CONSTANTS[87]*(( STATES[11]*STATES[19])/( CONSTANTS[85]*CONSTANTS[83])) - CONSTANTS[113]*(( STATES[12]*STATES[20])/( CONSTANTS[82]*CONSTANTS[84])))/(1.00000+STATES[11]/CONSTANTS[85]+STATES[19]/CONSTANTS[83]+( STATES[11]*STATES[19])/( CONSTANTS[85]*CONSTANTS[83])+STATES[12]/CONSTANTS[82]+STATES[20]/CONSTANTS[84]+( STATES[12]*STATES[20])/( CONSTANTS[82]*CONSTANTS[84])); ALGEBRAIC[16] = ( CONSTANTS[114]*(( STATES[15]*STATES[18])/( CONSTANTS[92]*CONSTANTS[89])) - CONSTANTS[94]*(( STATES[14]*STATES[17])/( CONSTANTS[88]*CONSTANTS[90])))/(1.00000+STATES[14]/CONSTANTS[88]+STATES[17]/CONSTANTS[91]+( STATES[14]*STATES[17])/( CONSTANTS[88]*CONSTANTS[90])+STATES[15]/CONSTANTS[92]+( STATES[15]*STATES[18])/( CONSTANTS[92]*CONSTANTS[89])); ALGEBRAIC[17] = ( CONSTANTS[99]*(( STATES[15]*STATES[16])/( CONSTANTS[97]*CONSTANTS[96])) - CONSTANTS[115]*(pow(STATES[14], 2.00000)/pow(CONSTANTS[95], 2.00000)))/(1.00000+STATES[15]/CONSTANTS[97]+STATES[16]/CONSTANTS[96]+( STATES[15]*STATES[16])/( CONSTANTS[97]*CONSTANTS[96])+( 2.00000*STATES[14])/CONSTANTS[95]+pow(STATES[14], 2.00000)/pow(CONSTANTS[95], 2.00000)); ALGEBRAIC[1] = ( CONSTANTS[11]*(( STATES[0]*STATES[13])/( CONSTANTS[3]*CONSTANTS[9])) - CONSTANTS[100]*(( STATES[0]*STATES[1])/( CONSTANTS[4]*CONSTANTS[10])))/(1.00000+STATES[0]/CONSTANTS[3]+STATES[13]/CONSTANTS[8]+STATES[0]/CONSTANTS[4]+STATES[1]/CONSTANTS[10]+( STATES[0]*STATES[13])/( CONSTANTS[5]*CONSTANTS[8])+( STATES[0]*STATES[1])/( CONSTANTS[6]*CONSTANTS[10])); ALGEBRAIC[2] = (( CONSTANTS[23]*(( STATES[0]*STATES[13])/( CONSTANTS[12]*CONSTANTS[20])) - CONSTANTS[101]*(( STATES[0]*STATES[1])/( CONSTANTS[13]*CONSTANTS[21])))/(1.00000+STATES[0]/CONSTANTS[12]+STATES[13]/CONSTANTS[19]+STATES[0]/CONSTANTS[13]+STATES[1]/CONSTANTS[21]+( STATES[0]*STATES[13])/( CONSTANTS[14]*CONSTANTS[19])+( STATES[0]*STATES[1])/( CONSTANTS[18]*CONSTANTS[21])))*((pow(STATES[16], CONSTANTS[16])/CONSTANTS[17])/(1.00000+pow(STATES[16], CONSTANTS[16])/CONSTANTS[17])); ALGEBRAIC[18] = CONSTANTS[1]*ALGEBRAIC[1]+ CONSTANTS[2]*ALGEBRAIC[2]; ALGEBRAIC[7] = CONSTANTS[43]*pow( ((1.00000+STATES[15]/CONSTANTS[40])/(1.00000+ CONSTANTS[44]*(STATES[15]/CONSTANTS[40])))*((1.00000+ CONSTANTS[45]*(STATES[16]/CONSTANTS[41]))/(1.00000+STATES[16]/CONSTANTS[41])), 4.00000); ALGEBRAIC[5] = (1.00000+STATES[3]/CONSTANTS[34])*(1.00000+STATES[15]/CONSTANTS[35])+STATES[14]/CONSTANTS[38]+ (STATES[4]/CONSTANTS[32])*(1.00000+STATES[14]/CONSTANTS[38]); ALGEBRAIC[6] = (1.00000+STATES[3]/CONSTANTS[36])*(1.00000+STATES[15]/CONSTANTS[37])+STATES[14]/CONSTANTS[39]+ (STATES[4]/CONSTANTS[33])*(1.00000+STATES[14]/CONSTANTS[39]); ALGEBRAIC[19] = (( CONSTANTS[42]*(( STATES[15]*STATES[3])/( CONSTANTS[35]*CONSTANTS[34])) - CONSTANTS[104]*(( STATES[14]*STATES[4])/( CONSTANTS[38]*CONSTANTS[32])))/ALGEBRAIC[5])*((1.00000+ CONSTANTS[105]*ALGEBRAIC[7]*pow(ALGEBRAIC[6]/ALGEBRAIC[5], 3.00000))/(1.00000+ ALGEBRAIC[7]*pow(ALGEBRAIC[6]/ALGEBRAIC[5], 4.00000))); ALGEBRAIC[10] = 1.00000+STATES[6]/CONSTANTS[55]+STATES[20]/CONSTANTS[57]+STATES[13]/CONSTANTS[56]+( STATES[6]*STATES[20])/( CONSTANTS[55]*CONSTANTS[57])+( STATES[6]*STATES[20]*STATES[13])/( CONSTANTS[55]*CONSTANTS[57]*CONSTANTS[56])+STATES[7]/CONSTANTS[59]+STATES[19]/CONSTANTS[58]+( STATES[7]*STATES[19])/( CONSTANTS[59]*CONSTANTS[58]); ALGEBRAIC[20] = ( CONSTANTS[61]*(( STATES[6]*STATES[20]*STATES[13])/( CONSTANTS[55]*CONSTANTS[57]*CONSTANTS[56])) - CONSTANTS[108]*(( STATES[7]*STATES[19])/( CONSTANTS[59]*CONSTANTS[58])))/ALGEBRAIC[10]; } void getStateInformation(double* SI) { SI[0] = 1.0; SI[1] = 1.0; SI[2] = 1.0; SI[3] = 1.0; SI[4] = 1.0; SI[5] = 1.0; SI[6] = 1.0; SI[7] = 1.0; SI[8] = 1.0; SI[9] = 1.0; SI[10] = 1.0; SI[11] = 1.0; SI[12] = 1.0; SI[13] = 1.0; SI[14] = 1.0; SI[15] = 1.0; SI[16] = 1.0; SI[17] = 1.0; SI[18] = 1.0; SI[19] = 1.0; SI[20] = 1.0; } void computeRoots(double VOI, double* CONSTANTS, double* RATES, double* OLDRATES, double* STATES, double* OLDSTATES, double* ALGEBRAIC, double* CONDVARS) { }