C C There are a total of 13 entries in the algebraic variable array. C There are a total of 4 entries in each of the rate and state variable arrays. C There are a total of 24 entries in the constant variable array. C C C VOI is time in component environment (millisecond). C STATES(1) is V in component membrane (millivolt). C CONSTS(1) is C in component membrane (picoF). C CONSTS(2) is i_app in component membrane (picoA). C ALGBRC(11) is i_NaP in component persistent_sodium_current (picoA). C ALGBRC(5) is i_Na in component fast_sodium_current (picoA). C ALGBRC(9) is i_K in component potassium_current (picoA). C ALGBRC(12) is i_L in component leakage_current (picoA). C ALGBRC(13) is i_tonic_e in component tonic_current (picoA). C CONSTS(3) is E_Na in component fast_sodium_current (millivolt). C CONSTS(4) is g_Na in component fast_sodium_current (nanoS). C ALGBRC(1) is m_infinity in component fast_sodium_current_m_gate (dimensionless). C STATES(2) is n in component fast_sodium_current_n_gate (dimensionless). C CONSTS(5) is theta_m in component fast_sodium_current_m_gate (millivolt). C CONSTS(6) is sigma_m in component fast_sodium_current_m_gate (millivolt). C ALGBRC(2) is n_infinity in component fast_sodium_current_n_gate (dimensionless). C ALGBRC(6) is tau_n in component fast_sodium_current_n_gate (millisecond). C CONSTS(7) is tau_n_max in component fast_sodium_current_n_gate (millisecond). C CONSTS(8) is theta_n in component fast_sodium_current_n_gate (millivolt). C CONSTS(9) is sigma_n in component fast_sodium_current_n_gate (millivolt). C CONSTS(10) is g_K in component potassium_current (nanoS). C CONSTS(11) is E_K in component potassium_current (millivolt). C STATES(3) is n in component potassium_current_n_gate (dimensionless). C ALGBRC(3) is n_infinity in component potassium_current_n_gate (dimensionless). C ALGBRC(7) is tau_n in component potassium_current_n_gate (millisecond). C CONSTS(12) is tau_n_max in component potassium_current_n_gate (millisecond). C CONSTS(13) is theta_n in component potassium_current_n_gate (millivolt). C CONSTS(14) is sigma_n in component potassium_current_n_gate (millivolt). C CONSTS(15) is g_NaP in component persistent_sodium_current (nanoS). C ALGBRC(10) is m_infinity in component persistent_sodium_current_m_gate (dimensionless). C STATES(4) is h in component persistent_sodium_current_h_gate (dimensionless). C CONSTS(16) is theta_m in component persistent_sodium_current_m_gate (millivolt). C CONSTS(17) is sigma_m in component persistent_sodium_current_m_gate (millivolt). C ALGBRC(4) is h_infinity in component persistent_sodium_current_h_gate (dimensionless). C ALGBRC(8) is tau_h in component persistent_sodium_current_h_gate (millisecond). C CONSTS(18) is tau_h_max in component persistent_sodium_current_h_gate (millisecond). C CONSTS(19) is theta_h in component persistent_sodium_current_h_gate (millivolt). C CONSTS(20) is sigma_h in component persistent_sodium_current_h_gate (millivolt). C CONSTS(21) is g_L in component leakage_current (nanoS). C CONSTS(22) is E_L in component leakage_current (millivolt). C CONSTS(23) is g_tonic_e in component tonic_current (nanoS). C CONSTS(24) is E_syn_e in component tonic_current (millivolt). C RATES(1) is d/dt V in component membrane (millivolt). C RATES(2) is d/dt n in component fast_sodium_current_n_gate (dimensionless). C RATES(3) is d/dt n in component potassium_current_n_gate (dimensionless). C RATES(4) is d/dt h in component persistent_sodium_current_h_gate (dimensionless). C SUBROUTINE initConsts(CONSTS, RATES, STATES) REAL CONSTS(*), RATES(*), STATES(*) STATES(1) = -50.0 CONSTS(1) = 21.0 CONSTS(2) = 0.0 CONSTS(3) = 50.0 CONSTS(4) = 28.0 STATES(2) = 0.01 CONSTS(5) = -34.0 CONSTS(6) = -5.0 CONSTS(7) = 10.0 CONSTS(8) = -29.0 CONSTS(9) = -4.0 CONSTS(10) = 11.2 CONSTS(11) = -85.0 STATES(3) = 0.01 CONSTS(12) = 10.0 CONSTS(13) = -29.0 CONSTS(14) = -4.0 CONSTS(15) = 2.8 STATES(4) = 0.46 CONSTS(16) = -40.0 CONSTS(17) = -6.0 CONSTS(18) = 10000.0 CONSTS(19) = -48.0 CONSTS(20) = 6.0 CONSTS(21) = 2.8 CONSTS(22) = -57.5 CONSTS(23) = 0.0 CONSTS(24) = 0.0 RETURN END SUBROUTINE computeRates(VOI, CONSTS, RATES, STATES, ALGBRC) REAL VOI, CONSTS(*), RATES(*), STATES(*), ALGBRC(*) ALGBRC(2) = 1.00000/(1.00000+EXP((STATES(1) - CONSTS(8))/CONSTS(9))) ALGBRC(6) = CONSTS(7)/cosh((STATES(1) - CONSTS(8))/( 2.00000*CONSTS(9))) RATES(2) = (ALGBRC(2) - STATES(2))/ALGBRC(6) ALGBRC(3) = 1.00000/(1.00000+EXP((STATES(1) - CONSTS(13))/CONSTS(14))) ALGBRC(7) = CONSTS(12)/cosh((STATES(1) - CONSTS(13))/( 2.00000*CONSTS(14))) RATES(3) = (ALGBRC(3) - STATES(3))/ALGBRC(7) ALGBRC(4) = 1.00000/(1.00000+EXP((STATES(1) - CONSTS(19))/CONSTS(20))) ALGBRC(8) = CONSTS(18)/cosh((STATES(1) - CONSTS(19))/( 2.00000*CONSTS(20))) RATES(4) = (ALGBRC(4) - STATES(4))/ALGBRC(8) ALGBRC(10) = 1.00000/(1.00000+EXP((STATES(1) - CONSTS(16))/CONSTS(17))) ALGBRC(11) = CONSTS(15)*ALGBRC(10)*STATES(4)*(STATES(1) - CONSTS(3)) ALGBRC(1) = 1.00000/(1.00000+EXP((STATES(1) - CONSTS(5))/CONSTS(6))) ALGBRC(5) = CONSTS(4)*ALGBRC(1) ** 3.00000*(1.00000 - STATES(2))*(STATES(1) - CONSTS(3)) ALGBRC(9) = CONSTS(10)*STATES(3) ** 4.00000*(STATES(1) - CONSTS(11)) ALGBRC(12) = CONSTS(21)*(STATES(1) - CONSTS(22)) ALGBRC(13) = CONSTS(23)*(STATES(1) - CONSTS(24)) RATES(1) = (- (ALGBRC(11)+ALGBRC(5)+ALGBRC(9)+ALGBRC(12)+ALGBRC(13))+CONSTS(2))/CONSTS(1) RETURN END SUBROUTINE computeVariables(VOI, CONSTS, RATES, STATES, ALGBRC) REAL VOI, CONSTS(*), RATES(*), STATES(*), ALGBRC(*) ALGBRC(2) = 1.00000/(1.00000+EXP((STATES(1) - CONSTS(8))/CONSTS(9))) ALGBRC(6) = CONSTS(7)/cosh((STATES(1) - CONSTS(8))/( 2.00000*CONSTS(9))) ALGBRC(3) = 1.00000/(1.00000+EXP((STATES(1) - CONSTS(13))/CONSTS(14))) ALGBRC(7) = CONSTS(12)/cosh((STATES(1) - CONSTS(13))/( 2.00000*CONSTS(14))) ALGBRC(4) = 1.00000/(1.00000+EXP((STATES(1) - CONSTS(19))/CONSTS(20))) ALGBRC(8) = CONSTS(18)/cosh((STATES(1) - CONSTS(19))/( 2.00000*CONSTS(20))) ALGBRC(10) = 1.00000/(1.00000+EXP((STATES(1) - CONSTS(16))/CONSTS(17))) ALGBRC(11) = CONSTS(15)*ALGBRC(10)*STATES(4)*(STATES(1) - CONSTS(3)) ALGBRC(1) = 1.00000/(1.00000+EXP((STATES(1) - CONSTS(5))/CONSTS(6))) ALGBRC(5) = CONSTS(4)*ALGBRC(1) ** 3.00000*(1.00000 - STATES(2))*(STATES(1) - CONSTS(3)) ALGBRC(9) = CONSTS(10)*STATES(3) ** 4.00000*(STATES(1) - CONSTS(11)) ALGBRC(12) = CONSTS(21)*(STATES(1) - CONSTS(22)) ALGBRC(13) = CONSTS(23)*(STATES(1) - CONSTS(24)) RETURN END