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C C There are a total of 6 entries in the algebraic variable array. C There are a total of 5 entries in each of the rate and state variable arrays. C There are a total of 20 entries in the constant variable array. C C C VOI is time in component environment (minute). C STATES(1) is C in component C (dimensionless). C ALGBRC(1) is Ctot in component C (dimensionless). C CONSTS(1) is vi in component model_parameters (per_minute). C CONSTS(2) is k1 in component model_parameters (per_minute). C STATES(2) is X in component X (dimensionless). C CONSTS(3) is K5 in component model_parameters (dimensionless). C CONSTS(4) is kd in component model_parameters (per_minute). C STATES(3) is Z in component Z (dimensionless). C STATES(4) is M in component M (dimensionless). C CONSTS(20) is M_ in component M (dimensionless). C ALGBRC(2) is V1 in component model_parameters (per_minute). C CONSTS(5) is K1 in component model_parameters (dimensionless). C CONSTS(6) is V2 in component model_parameters (per_minute). C CONSTS(7) is K2 in component model_parameters (dimensionless). C ALGBRC(3) is X_ in component X (dimensionless). C ALGBRC(5) is V3 in component model_parameters (per_minute). C CONSTS(8) is K3 in component model_parameters (dimensionless). C CONSTS(9) is V4 in component model_parameters (per_minute). C CONSTS(10) is K4 in component model_parameters (dimensionless). C STATES(5) is Y in component Y (dimensionless). C ALGBRC(4) is Ytot in component Y (dimensionless). C CONSTS(11) is vs in component model_parameters (per_minute). C CONSTS(12) is d1 in component model_parameters (per_minute). C CONSTS(13) is a1 in component model_parameters (per_minute). C CONSTS(14) is a2 in component model_parameters (per_minute). C CONSTS(15) is alpha in component model_parameters (dimensionless). C ALGBRC(6) is BP in component BP (dimensionless). C CONSTS(16) is Kd in component model_parameters (dimensionless). C CONSTS(17) is K6 in component model_parameters (dimensionless). C CONSTS(18) is V1_dash in component model_parameters (per_minute). C CONSTS(19) is V3_dash in component model_parameters (per_minute). C RATES(1) is d/dt C in component C (dimensionless). C RATES(4) is d/dt M in component M (dimensionless). C RATES(2) is d/dt X in component X (dimensionless). C RATES(5) is d/dt Y in component Y (dimensionless). C RATES(3) is d/dt Z in component Z (dimensionless). C SUBROUTINE initConsts(CONSTS, RATES, STATES) REAL CONSTS(*), RATES(*), STATES(*) STATES(1) = 0.01 CONSTS(1) = 0.1 CONSTS(2) = 0.5 STATES(2) = 0.01 CONSTS(3) = 0.02 CONSTS(4) = 0.02 STATES(3) = 0.28 STATES(4) = 0.01 CONSTS(5) = 0.02 CONSTS(6) = 0.25 CONSTS(7) = 0.02 CONSTS(8) = 0.1 CONSTS(9) = 0.1 CONSTS(10) = 0.1 STATES(5) = 0.01 CONSTS(11) = 0.1 CONSTS(12) = 0.05 CONSTS(13) = 1.5 CONSTS(14) = 1.5 CONSTS(15) = 0.1 CONSTS(16) = 1 CONSTS(17) = 0.3 CONSTS(18) = 0.75 CONSTS(19) = 0.3 CONSTS(20) = - 1.00000 RETURN END SUBROUTINE computeRates(VOI, CONSTS, RATES, STATES, ALGBRC) REAL VOI, CONSTS(*), RATES(*), STATES(*), ALGBRC(*) RATES(1) = (CONSTS(1) - ( CONSTS(2)*STATES(2)*STATES(1))/(STATES(1)+CONSTS(3))) - CONSTS(4)*STATES(1) RATES(5) = ((CONSTS(11) - CONSTS(12)*STATES(5)) - CONSTS(13)*STATES(1)*STATES(5))+ (CONSTS(14)+ CONSTS(15)*CONSTS(4))*STATES(3) RATES(3) = CONSTS(13)*STATES(1)*STATES(5) - (CONSTS(14)+ CONSTS(15)*CONSTS(4)+ CONSTS(15)*CONSTS(12))*STATES(3) ALGBRC(2) = ( STATES(1)*CONSTS(18))/(STATES(1)+CONSTS(17)) RATES(4) = ( ALGBRC(2)*CONSTS(20))/(CONSTS(20)+CONSTS(5)) - ( CONSTS(6)*STATES(4))/(STATES(4)+CONSTS(7)) ALGBRC(3) = 1.00000 - STATES(2) ALGBRC(5) = STATES(4)*CONSTS(19) RATES(2) = ( ALGBRC(5)*ALGBRC(3))/(ALGBRC(3)+CONSTS(8)) - ( CONSTS(9)*STATES(2))/(STATES(2)+CONSTS(10)) RETURN END SUBROUTINE computeVariables(VOI, CONSTS, RATES, STATES, ALGBRC) REAL VOI, CONSTS(*), RATES(*), STATES(*), ALGBRC(*) ALGBRC(2) = ( STATES(1)*CONSTS(18))/(STATES(1)+CONSTS(17)) ALGBRC(3) = 1.00000 - STATES(2) ALGBRC(5) = STATES(4)*CONSTS(19) ALGBRC(1) = STATES(1)+STATES(3) ALGBRC(4) = STATES(5)+STATES(3) ALGBRC(6) = 1.00000+( CONSTS(16)*ALGBRC(4))/STATES(1)+CONSTS(16) ** 2.00000 RETURN END