The Sneyd-Dufour 2002 dynamic model of the type-2 inositol triphosphate receptor.
99
A dynamic model of the type-2 inositol triphosphate receptor
2403
2398
Jean-Francois
Dufour
The University of Auckland, Auckland Bioengineering Institute
10000
0.1
1.5
Active state
A
Auckland Bioengineering Institute
The University of Auckland
Inactive state 2
I_1
O
Open state
May
Lloyd
Catherine
2007-05-24T08:10:03+12:00
2007-05-22T00:00:00+00:00
c.lloyd@auckland.ac.nz
The new version of this model has been re-coded to remove the reaction element and replace it with a simple MathML description of the model reaction kinetics. This is thought to be truer to the original publication, and information regarding the enzyme kinetics etc will later be added to the metadata through use of an ontology. The model runs in the PCEnv simulator and gives a nice curved output.
calcium dynamics
IP3 receptor
James
Sneyd
S
Shut state
Lloyd
May
Catherine
Corrected two of the equations.
2002-02-19
Lloyd
May
Catherine
2007-06-05T10:45:11+12:00
keyword
11842185
Inactive state 1
I_1
This is the CellML description of Sneyd and Dufour's 2002 dynamic model of type-2 inositol triphosphate receptor. The dynamic properties of this receptor are essential for the control of intracellular calcium, including the generation of calcium oscillations and waves.
Catherine Lloyd
PNAS
R
Receptor