C C There are a total of 0 entries in the algebraic variable array. C There are a total of 4 entries in each of the rate and state variable arrays. C There are a total of 10 entries in the constant variable array. C C C VOI is time in component environment (day). C CONSTS(1) is lambda in component uninfected (per_ml_day). C CONSTS(2) is d_T in component uninfected (per_day). C CONSTS(3) is efficacy in component drug_efficacy (dimensionless). C CONSTS(4) is k in component uninfected (ml_per_day). C STATES(1) is V in component viral_load (per_ml). C STATES(2) is T in component uninfected (per_ml). C CONSTS(5) is d_0 in component latently_infected (per_day). C CONSTS(6) is a_L in component latently_infected (per_day). C CONSTS(7) is eta in component latently_infected (dimensionless). C STATES(3) is L in component latently_infected (per_ml). C CONSTS(8) is delta in component productively_infected (per_day). C STATES(4) is T_star in component productively_infected (per_ml). C CONSTS(9) is N in component viral_load (dimensionless). C CONSTS(10) is c in component viral_load (per_day). C RATES(2) is d/dt T in component uninfected (per_ml). C RATES(3) is d/dt L in component latently_infected (per_ml). C RATES(4) is d/dt T_star in component productively_infected (per_ml). C RATES(1) is d/dt V in component viral_load (per_ml). C SUBROUTINE initConsts(CONSTS, RATES, STATES) REAL CONSTS(*), RATES(*), STATES(*) CONSTS(1) = 1E4 CONSTS(2) = 0.01 CONSTS(3) = 0.4 CONSTS(4) = 2.4E-8 STATES(1) = 50 STATES(2) = 600000 CONSTS(5) = 0.001 CONSTS(6) = 0.1 CONSTS(7) = 0.001 STATES(3) = 2 CONSTS(8) = 1 STATES(4) = 0.3 CONSTS(9) = 2000 CONSTS(10) = 23 RETURN END SUBROUTINE computeRates(VOI, CONSTS, RATES, STATES, ALGBRC) REAL VOI, CONSTS(*), RATES(*), STATES(*), ALGBRC(*) RATES(2) = (CONSTS(1) - CONSTS(2)*STATES(2)) - (1.00000 - CONSTS(3))*CONSTS(4)*STATES(1)*STATES(2) RATES(3) = ( CONSTS(7)*(1.00000 - CONSTS(3))*CONSTS(4)*STATES(1)*STATES(2) - CONSTS(5)*STATES(3)) - CONSTS(6)*STATES(3) RATES(4) = ( (1.00000 - CONSTS(7))*(1.00000 - CONSTS(3))*CONSTS(4)*STATES(1)*STATES(2) - CONSTS(8)*STATES(4))+ CONSTS(6)*STATES(3) RATES(1) = CONSTS(9)*CONSTS(8)*STATES(4) - CONSTS(10)*STATES(1) RETURN END SUBROUTINE computeVariables(VOI, CONSTS, RATES, STATES, ALGBRC) REAL VOI, CONSTS(*), RATES(*), STATES(*), ALGBRC(*) RETURN END