You are here: Home / Exposures / Vilar, Jansen, Sander, 2006 / Signal processing in the TGF-beta superfamily ligand-receptor network (Reaction Form)

Model Mathematics

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Component: environment

Component: v1

v1 = ka l RI RII

Component: v2

v2 = kcd l_RI_RII

Component: v3

v3 = klid l_RI_RII

Component: v4

v4 = ki l_RI_RII

Component: v5

v5 = p_RI

Component: v6

v6 = kcd RI

Component: v7

v7 = ki RI

Component: v8

v8 = kr RI_endo

Component: v9

v9 = kr l_RI_RII_endo

Component: v10

v10 = p_RII

Component: v11

v11 = kcd RII

Component: v12

v12 = ki RII

Component: v13

v13 = kr RII_endo

Component: l

l = \{\begin{matrix} 0.01 if time \geq 2500 \\ 0.00003 otherwise \end{matrix}

Component: l_RI_RII

\frac{d}{d time} (l_RI_RII) = v1 - (v2 + v3 + v4)

Component: RI

\frac{d}{d time} (RI) = v5 + v8 + v9 - (v1 + v6 + v7)

Component: RII

\frac{d}{d time} (RII) = v9 + v10 + v13 - (v1 + v11 + v12)

Component: l_RI_RII_endo

\frac{d}{d time} (l_RI_RII_endo) = v4 - v9

Component: RI_endo

\frac{d}{d time} (RI_endo) = v7 - v8

Component: RII_endo

\frac{d}{d time} (RII_endo) = v12 - v13

Component: model_parameters

Source: Derived from workspace Vilar 2006 at changeset 602b1f6a4a4d.

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License: This work is licensed under a Creative Commons Attribution 3.0 Unported License.