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Reed, Nijhout, Sparks, Ulrich, 2004
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A mathematical model of the methionine cycle
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Model Mathematics
Component based math viewer is available
Component: environment
Metin
=
200
if
time
<
2
∨
time
≥
8
300
if
time
≥
2
∧
time
<
5
100
if
time
≥
5
∧
time
<
8
200
otherwise
Component: Met
d
d
time
Met
=
V_MS
+
V_BHMT
+
Metin
-
V_MATI
+
V_MATIII
Component: AdoMet
d
d
time
AdoMet
=
V_MATI
+
V_MATIII
-
V_METH
+
V_GNMT
Component: AdoHcy
d
d
time
AdoHcy
=
V_METH
+
V_GNMT
-
V_AH
Component: Hcy
d
d
time
Hcy
=
V_AH
-
V_CBS
+
V_MS
+
V_BHMT
Component: V_MATI
V_MATI
=
V_MATImax
1
+
Km_MATI
Met
1
+
AdoMet
Ki_MATI
Component: V_MATIII
V_MATIII
=
V_MATIIImax
1
+
Km1_MATIII
Km2_MATIII
Met
2
+
Met
Km2_MATIII
Km1_MATIII
=
20000
1
+
5.7
AdoMet
AdoMet
+
600
2
Component: V_GNMT
V_GNMT
=
V_GNMTmax
1
+
Km_GNMT
AdoMet
2.3
1
1
+
AdoHcy
Ki_GNMT
Component: V_METH
V_METH
=
V_METHmax
1
+
Km1_METH
AdoMet
+
Km2_METH_A
+
Km2_METH_A
Km1_METH
AdoMet
Km1_METH
=
1
1
+
AdoHcy
4
Component: V_MS
V_MS
=
V_MSmax
five_mTHF
Hcy
Kd_MS
Km_Hcy_MS
+
Km_Hcy_MS
five_mTHF
+
Km_five_mTHF_MS
Hcy
+
five_mTHF
Hcy
Component: V_AH
V_AH
=
alpha1
AdoHcy
-
alpha2
Hcy
Component: V_CBS
V_CBS
=
beta1
AdoMet
+
AdoHcy
-
beta2
Hcy
Component: V_BHMT
V_BHMT
=
0.7
-
0.025
AdoMet
+
AdoHcy
-
150
V_BHMTmax
Hcy
Km_BHMT
+
Hcy
Source
Derived from workspace
Reed, Nijhout, Sparks, Ulrich, 2004
at changeset
8f85c7aa211e
.
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This work is licensed under a
Creative Commons Attribution 3.0 Unported License
.
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A mathematical model of the methionine cycle