x20
percentage of intracellular GLUT4
x18
percentage of unactivated PKC-zeta
E1101
283
283
A mathematical model of metabolic insulin signaling pathways
E1084
E1101
A mathematical model of metabolic insulin signaling pathways
E1084
insulin input
x1
Sedaghat, Sherman and Quon's 2002 mathematical model of metabolic insulin signaling pathways.
The University of Auckland
Auckland Bioengineering Institute
The University of Auckland
Auckland Bioengineering Institute
May
Catherine
Lloyd
Catherine
Lloyd
May
x11
concentration of unactivated PI 3-kinase
signal transduction
insulin
metabolism
metabolism
signal transduction
insulin
Ahmad
R
Sedaghat
Ahmad
Sedaghat
R
May
Catherine
Lloyd
Catherine
Lloyd
May
x20
percentage of intracellular GLUT4
x2
concentration of unbound surface insulin receptors
percentage of cell surface GLUT4
x21
x13
percentage of PI(3,4,5)P3 out of the total lipid population
x7
concentration of phosphorylated twice-bound intracellular receptors
Catherine Lloyd
Catherine Lloyd
The new version of this model has been re-coded to remove the reaction element and replace it with a simple MathML description of the model reaction kinetics. This is thought to be truer to the original publication, and information regarding the enzyme kinetics etc will later be added to the metadata through use of an ontology.
The new version of this model has been re-coded to remove the reaction element and replace it with a simple MathML description of the model reaction kinetics. This is thought to be truer to the original publication, and information regarding the enzyme kinetics etc will later be added to the metadata through use of an ontology.
The University of Auckland, Bioengineering Institute
A mathematical model of metabolic insulin signaling pathways (without feedback)
percentage of PI(3,4,5)P3 out of the total lipid population
x13
x14
percentage of PI(4,5)P2 out of the total lipid population
percentage of unactivated Akt
x16
The University of Auckland, Auckland Bioengineering Institute
A mathematical model of metabolic insulin signaling pathways (with feedback)
x5
concentration of phosphorylated once-bound surface receptors
2002-11
2002-11
percentage of unactivated Akt
x16
0.01
percentage of activated Akt
x17
concentration of tyrosine-phosphorylated IRS-1
x10
concentration of unactivated PI 3-kinase
x11
2007-05-30T00:00:00+00:00
2007-05-30T00:00:00+00:00
percentage of activated Akt
x17
This is the CellML descripition of Sedaghat, Sherman and Quon's 2002
mathematical model of metabolic insulin signaling pathways.
This is the CellML descripition of Sedaghat, Sherman and Quon's 2002
mathematical model of metabolic insulin signaling pathways.
x9
concentration of unphosphorylated IRS-1
Michael
Michael
Quon
Quon
J
J
percentage of unactivated PKC-zeta
x18
concentration of phosphorylated once-bound intracellular receptors
x8
concentration of unphosphorylated once-bound surface receptors
x3
percentage of PI(3,4)P2 out of the total lipid population
x15
concentration of tyrosine-phosphorylated IRS-1/activated PI 3-kinase complex
x12
x10a
concentration of serine-phosphorylated IRS-1
concentration of unbound unphosphorylated intracellular receptors
x6
x19
percentage of activated PKC-zeta
x5
concentration of phosphorylated once-bound surface receptors
x10
concentration of tyrosine-phosphorylated IRS-1
concentration of phosphorylated twice-bound intracellular receptors
x7
concentration of phosphorylated twice-bound surface receptors
x4
Sherman
Sherman
Arthur
Arthur
percentage of PI(3,4)P2 out of the total lipid population
x15
insulin input
x1
Sedaghat, Sherman and Quon's 2002 mathematical model of metabolic insulin signaling pathways.
concentration of unbound surface insulin receptors
x2
x12
concentration of tyrosine-phosphorylated IRS-1/activated PI 3-kinase complex
concentration of phosphorylated once-bound intracellular receptors
x8
percentage of activated PKC-zeta
x19
12376338
12376338
percentage of cell surface GLUT4
x21
American Journal of Physiology
American Journal of Physiology
keyword
keyword
c.lloyd@auckland.ac.nz
c.lloyd@auckland.ac.nz
concentration of unphosphorylated IRS-1
x9
percentage of PI(4,5)P2 out of the total lipid population
x14
2007-06-05T10:44:09+12:00
2007-06-05T10:44:09+12:00
concentration of unbound unphosphorylated intracellular receptors
x6
x4
concentration of phosphorylated twice-bound surface receptors
x3
concentration of unphosphorylated once-bound surface receptors