percentage of activated Akt
x17
x14
percentage of PI(4,5)P2 out of the total lipid population
x6
concentration of unbound unphosphorylated intracellular receptors
percentage of unactivated Akt
x16
x11
concentration of unactivated PI 3-kinase
x7
concentration of phosphorylated twice-bound intracellular receptors
keyword
The new version of this model has been re-coded to remove the reaction element and replace it with a simple MathML description of the model reaction kinetics. This is thought to be truer to the original publication, and information regarding the enzyme kinetics etc will later be added to the metadata through use of an ontology.
May
Catherine
Lloyd
c.lloyd@auckland.ac.nz
x12
concentration of tyrosine-phosphorylated IRS-1/activated PI 3-kinase complex
R
Sedaghat
Ahmad
Sedaghat, Sherman and Quon's 2002 mathematical model of metabolic insulin signaling pathways.
E1101
A mathematical model of metabolic insulin signaling pathways
283
E1084
12376338
percentage of PI(3,4,5)P3 out of the total lipid population
x13
A mathematical model of metabolic insulin signaling pathways (without feedback)
The University of Auckland, Bioengineering Institute
x2
concentration of unbound surface insulin receptors
0.01
American Journal of Physiology
Auckland Bioengineering Institute
The University of Auckland
x5
concentration of phosphorylated once-bound surface receptors
x8
concentration of phosphorylated once-bound intracellular receptors
insulin
metabolism
signal transduction
x15
percentage of PI(3,4)P2 out of the total lipid population
x19
percentage of activated PKC-zeta
x20
percentage of intracellular GLUT4
2007-05-30T00:00:00+00:00
2002-11
x9
concentration of unphosphorylated IRS-1
Sherman
Arthur
concentration of tyrosine-phosphorylated IRS-1
x10
Michael
Quon
J
insulin input
x1
Lloyd
May
Catherine
percentage of cell surface GLUT4
x21
Catherine Lloyd
This is the CellML descripition of Sedaghat, Sherman and Quon's 2002
mathematical model of metabolic insulin signaling pathways.
concentration of phosphorylated twice-bound surface receptors
x4
x18
percentage of unactivated PKC-zeta
2007-06-05T10:44:09+12:00
concentration of unphosphorylated once-bound surface receptors
x3