C C There are a total of 4 entries in the algebraic variable array. C There are a total of 5 entries in each of the rate and state variable arrays. C There are a total of 22 entries in the constant variable array. C C C VOI is time in component environment (day). C STATES(1) is R in component R (nanomolar). C CONSTS(1) is delta_R in component R (first_order_rate_constant). C ALGBRC(1) is f1 in component f1 (flux). C STATES(2) is U in component U (nanomolar). C CONSTS(2) is delta_U in component U (first_order_rate_constant). C CONSTS(3) is alpha0 in component model_parameters (per_nanomolar_day). C CONSTS(4) is alpha1 in component model_parameters (per_nanomolar_day). C CONSTS(5) is d01 in component model_parameters (first_order_rate_constant). C CONSTS(6) is d12 in component model_parameters (first_order_rate_constant). C STATES(3) is B1 in component B1 (nanomolar). C STATES(4) is B2 in component B2 (nanomolar). C ALGBRC(3) is P in component P (nanomolar). C ALGBRC(4) is f2 in component f2 (flux). C CONSTS(7) is delta_b1 in component B1 (first_order_rate_constant). C CONSTS(8) is delta_b2 in component B2 (first_order_rate_constant). C CONSTS(9) is PE in component P (nanomolar). C ALGBRC(2) is q in component P (dimensionless). C CONSTS(10) is G in component P (first_order_rate_constant). C CONSTS(11) is ti in component P (day). C CONSTS(12) is T in component P (day). C CONSTS(13) is P0 in component model_parameters (nanomolar). C CONSTS(14) is a in component f1 (flux). C CONSTS(15) is a0 in component f1 (flux). C CONSTS(16) is b in component f1 (nanomolar). C CONSTS(17) is b0 in component f1 (nanomolar). C STATES(5) is x in component x (flux). C CONSTS(18) is P1 in component x (nanomolar). C CONSTS(19) is s in component x (nanomolar_day2). C CONSTS(20) is delta_x in component x (first_order_rate_constant). C CONSTS(21) is kappa in component f2 (flux). C CONSTS(22) is kappa0 in component f2 (nanomolar). C RATES(1) is d/dt R in component R (nanomolar). C RATES(2) is d/dt U in component U (nanomolar). C RATES(3) is d/dt B1 in component B1 (nanomolar). C RATES(4) is d/dt B2 in component B2 (nanomolar). C RATES(5) is d/dt x in component x (flux). C SUBROUTINE initConsts(CONSTS, RATES, STATES) REAL CONSTS(*), RATES(*), STATES(*) STATES(1) = 1.0 CONSTS(1) = 1.905 STATES(2) = 1.0 CONSTS(2) = 7.5 CONSTS(3) = 4.15 CONSTS(4) = 3.02 CONSTS(5) = 13.0 CONSTS(6) = 4.72E3 STATES(3) = 1.0 STATES(4) = 1.0 CONSTS(7) = 7.5 CONSTS(8) = 50.0 CONSTS(9) = 20.55 CONSTS(10) = 35.6 CONSTS(11) = 1.0 CONSTS(12) = 9.0 CONSTS(13) = 0.25 CONSTS(14) = 3.58E5 CONSTS(15) = 2.33E4 CONSTS(16) = 100.0 CONSTS(17) = 263.0 STATES(5) = 1.0 CONSTS(18) = 20.0 CONSTS(19) = 3.71E5 CONSTS(20) = 0.207 CONSTS(21) = 2.4E5 CONSTS(22) = 6.55E3 RETURN END SUBROUTINE computeRates(VOI, CONSTS, RATES, STATES, ALGBRC) REAL VOI, CONSTS(*), RATES(*), STATES(*), ALGBRC(*) RATES(4) = CONSTS(4)*STATES(3)*STATES(2) - ( CONSTS(6)*STATES(4)+ CONSTS(8)*STATES(4)) ALGBRC(1) = CONSTS(15)*(1.00000 - STATES(4)/(CONSTS(16)+STATES(4)))+( STATES(5)*(1.00000 - EXP(- STATES(5)/CONSTS(14)))*STATES(4))/(CONSTS(17)+STATES(4)) RATES(1) = ALGBRC(1) - CONSTS(1)*STATES(1) ALGBRC(2) = TERNRY(VOI.LT.CONSTS(11), 0.00000, TERNRY(VOI.LT.CONSTS(12)+CONSTS(11).AND.VOI.GE.CONSTS(11), 1.00000 - EXP( - CONSTS(10)*(VOI - CONSTS(11))), EXP( CONSTS(10)*CONSTS(12) - 1.00000)*EXP( CONSTS(10)*(VOI - CONSTS(11)))) ALGBRC(3) = CONSTS(13)+ CONSTS(9)*ALGBRC(2) RATES(3) = ( CONSTS(3)*ALGBRC(3)*STATES(2)+ CONSTS(6)*STATES(4)) - ( CONSTS(5)*STATES(3)+ CONSTS(7)*STATES(3)+ CONSTS(4)*STATES(3)*STATES(2)) RATES(5) = ( CONSTS(19)*(ALGBRC(3) - CONSTS(13)))/(ALGBRC(3)+CONSTS(18)) - CONSTS(20)*STATES(5) ALGBRC(4) = ( CONSTS(21)*STATES(1))/(CONSTS(22)+STATES(1)) RATES(2) = (ALGBRC(4)+ CONSTS(5)*STATES(3)+ CONSTS(6)*STATES(4)) - ( CONSTS(2)*STATES(2)+ CONSTS(3)*ALGBRC(3)*STATES(2)+ CONSTS(4)*STATES(3)*STATES(2)) RETURN END SUBROUTINE computeVariables(VOI, CONSTS, RATES, STATES, ALGBRC) REAL VOI, CONSTS(*), RATES(*), STATES(*), ALGBRC(*) ALGBRC(1) = CONSTS(15)*(1.00000 - STATES(4)/(CONSTS(16)+STATES(4)))+( STATES(5)*(1.00000 - EXP(- STATES(5)/CONSTS(14)))*STATES(4))/(CONSTS(17)+STATES(4)) ALGBRC(2) = TERNRY(VOI.LT.CONSTS(11), 0.00000, TERNRY(VOI.LT.CONSTS(12)+CONSTS(11).AND.VOI.GE.CONSTS(11), 1.00000 - EXP( - CONSTS(10)*(VOI - CONSTS(11))), EXP( CONSTS(10)*CONSTS(12) - 1.00000)*EXP( CONSTS(10)*(VOI - CONSTS(11)))) ALGBRC(3) = CONSTS(13)+ CONSTS(9)*ALGBRC(2) ALGBRC(4) = ( CONSTS(21)*STATES(1))/(CONSTS(22)+STATES(1)) RETURN END REAL FUNCTION TERNRY(TEST, VALA, VALB) LOGICAL TEST REAL VALA, VALB IF (TEST) THEN TERNRY = VALA ELSE TERNRY = VALB ENDIF RETURN END