ARM1:
Calculation of the driving force for autoregulation in the muscles (PDO) by subtracting
a set-point value from the pressure of oxygen in the muscle tissues (PMO).
Muscle Blood Flow Control
cardiovascular circulation
physiology
organ systems
Guyton
muscle blood flow
500000
This is the CellML 1.1 "parent" file to test the Muscle Autoregulatory Local Blood Flow Control Model.
keyword
Guyton
Guyton
ARM12:
Multiplication of the outputs of the two parallel muscle autoregulatory
systems (AMM1 and AMM2) to given an overall multiplier factor for muscle
autoregulation (AMM) that in turn controls vascular resistance in the muscles.
Description of Guyton muscle blood flow control module
Description of Guyton muscle blood flow control module
Encapsulation grouping component containing all the components in the Muscle Autoregulatory Local Blood
Flow Control Model. The inputs and outputs of the Muscle Autoregulatory Local Blood Flow Control Model
must be passed by this component.
2008-00-00 00:00
Containment grouping component for "M_ST_sensitivity_control" and "M_ST_time_delay_and_damping".
ARM5, ARM6, and ARM7:
Time delay mechanism for the rapid autoregulation, allowing the output of
Block ARM7 (AMM1) to approach POE with a time constant of A4K.
The circulatory system is divided into three separate parts for blood flow control:
(1) the kidneys which are presented in an entirely separate section of this model;
(2) non-muscle local blood flow control; and (3) muscle local blood flow control.
Muscle Autoregulatory Local Blood Flow Control
Autoregulation in the muscles is similar to that in the non-muscle tissues except
that only two parallel autoregulatory circuits are given. One of these is an
extremely short-term autoregulatory circuit that allows rapid adjustment of muscle
blood flow to muscle metabolism during muscle activity, and the other is a very
long-term autoregulatory circuit.
ARM12:
Multiplication of the outputs of the two parallel muscle autoregulatory
systems (AMM1 and AMM2) to given an overall multiplier factor for muscle
autoregulation (AMM) that in turn controls vascular resistance in the muscles.
keyword
cardiovascular circulation
muscle blood flow
physiology
Guyton
organ systems
ARM2 and ARM3:
Sensitivity control for the short-term muscle autoregulation, controlled by the
variable (POM), and the driving output oxygen pressure is the variable POE.
ARM2 and ARM3:
Sensitivity control for the short-term muscle autoregulation, controlled by the
variable (POM), and the driving output oxygen pressure is the variable POE.
500000
100000
Component to set all input values to 1.0 or a prescribed value.
Muscle Blood Flow Control
ARM9, ARM10, and ARM11:
Time delay system for long-term autoregulation in muscle with a time constant
equal to A4K2 and an output of AMM2.
ARM8:
Sensitivity control for controlling the long-term autoregulation in the muscles.
The variable that controls the sensitivity is POM2.
ARM5, ARM6, and ARM7:
Time delay mechanism for the rapid autoregulation, allowing the output of
Block ARM7 (AMM1) to approach POE with a time constant of A4K.
ARM7A:
This sets a lower limit (AMM4) for the variable AMM1.
ARM7A:
This sets a lower limit (AMM4) for the variable AMM1.
Containment grouping component for "M_LT_sensitivity_control" and
"M_LT_time_delay".
ARM8:
Sensitivity control for controlling the long-term autoregulation in the muscles.
The variable that controls the sensitivity is POM2.
ARM1:
Calculation of the driving force for autoregulation in the muscles (PDO) by subtracting
a set-point value from the pressure of oxygen in the muscle tissues (PMO).
ARM9, ARM10, and ARM11:
Time delay system for long-term autoregulation in muscle with a time constant
equal to A4K2 and an output of AMM2.
2008-00-00 00:00
100000