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Kyrylov, Severyanova, Vieira, 2005
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Modeling robust oscillatory behavior of the hypothalamic-pituitary-adrenal axis
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Model Mathematics
Component based math viewer is available
Component: environment
Component: y0
d
d
time
y0
=
1.0
g0
+
c0
+
e0
g0
=
h0
r0
h0
=
a00
y0
+
a02
y2
1.0
+
a00
y0
+
a02
y2
S0
1.0
-
ⅇ
-
a00
y0
+
a02
y2
S0
if
a00
y0
+
a02
y2
>
0.0
a00
y0
+
a02
y2
if
a00
y0
+
a02
y2
≦
0.0
r0
=
1.0
-
ⅇ
S0
y0
2.0
a00
y0
+
a02
y2
epsilon
-
y0
2.0
if
y0
<
epsilon
∧
a00
y0
+
a02
y2
<
0.0
1.0
otherwise
Component: y1
d
d
time
y1
=
1.0
g1
+
e1
g1
=
h1
r1
h1
=
a10
y0
+
a11
y1
+
a12
y2
1.0
+
a10
y0
+
a11
y1
+
a12
y2
S1
1.0
-
ⅇ
-
a10
y0
+
a11
y1
+
a12
y2
S1
if
a10
y0
+
a11
y1
+
a12
y2
>
0.0
a10
y0
+
a11
y1
+
a12
y2
if
a10
y0
+
a11
y1
+
a12
y2
≦
0.0
r1
=
1.0
-
ⅇ
S1
y1
2.0
a10
y0
+
a11
y1
+
a12
y2
epsilon
-
y1
2.0
if
y1
<
epsilon
∧
a10
y0
+
a11
y1
+
a12
y2
<
0.0
1.0
otherwise
Component: y2
d
d
time
y2
=
1.0
g2
+
e2
g2
=
h2
r2
h2
=
a20
y0
+
a21
y1
+
a22
y2
+
a23
y3
+
a24
y4
1.0
+
a20
y0
+
a21
y1
+
a22
y2
+
a23
y3
+
a24
y4
S2
1.0
-
ⅇ
-
a20
y0
+
a21
y1
+
a22
y2
+
a23
y3
+
a24
y4
S2
if
a20
y0
+
a21
y1
+
a22
y2
+
a23
y3
+
a24
y4
>
0.0
a20
y0
+
a21
y1
+
a22
y2
+
a23
y3
+
a24
y4
if
a20
y0
+
a21
y1
+
a22
y2
+
a23
y3
+
a24
y4
≦
0.0
r2
=
1.0
-
ⅇ
S2
y2
2.0
a20
y0
+
a21
y1
+
a22
y2
+
a23
y3
+
a24
y4
epsilon
-
y2
2.0
if
y2
<
epsilon
∧
a20
y0
+
a21
y1
+
a22
y2
+
a23
y3
+
a24
y4
<
0.0
1.0
otherwise
Component: y3
d
d
time
y3
=
1.0
g3
g3
=
h3
r3
h3
=
a32
y2
+
a33
y3
1.0
+
a32
y2
+
a33
y3
S3
1.0
-
ⅇ
-
a32
y2
+
a33
y3
S3
if
a32
y2
+
a33
y3
>
0.0
a32
y2
+
a33
y3
if
a32
y2
+
a33
y3
≦
0.0
r3
=
1.0
-
ⅇ
S3
y3
2.0
a32
y2
+
a33
y3
epsilon
-
y3
2.0
if
y3
<
epsilon
∧
a32
y2
+
a33
y3
<
0.0
1.0
otherwise
Component: y4
d
d
time
y4
=
1.0
g4
g4
=
h4
r4
h4
=
a42
y2
+
a44
y4
1.0
+
a42
y2
+
a44
y4
S4
1.0
-
ⅇ
-
a42
y2
+
a44
y4
S4
if
a42
y2
+
a44
y4
>
0.0
a42
y2
+
a44
y4
if
a42
y2
+
a44
y4
≦
0.0
r4
=
1.0
-
ⅇ
S4
y4
2.0
a42
y2
+
a44
y4
epsilon
-
y4
2.0
if
y4
<
epsilon
∧
a42
y2
+
a44
y4
<
0.0
1.0
otherwise
Component: model_parameters
Source
Derived from workspace
Kyrylov, Severyanova, Vieira, 2005
at changeset
4d1519939d2a
.
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Creative Commons Attribution 3.0 Unported License
.
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Modeling robust oscillatory behavior of the hypothalamic-pituitary-adrenal axis