- Author:
- Tommy Yu <tommy.yu@auckland.ac.nz>
- Date:
- 2015-02-12 19:28:32+13:00
- Desc:
- Merging to remove the extra head
- Since the title is changed and in the interest of maintaining the
current structure we keep it as is.
- Permanent Source URI:
- https://models.cellml.org/w/matthiaskoenig/MetabolicComponentLibrary/rawfile/e0e2c28e2dfdfe37ea2cae3390a6ae26c28a3393/MetabolicComponentLibrary-v0.1.cellml
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<plus/>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
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<plus/>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
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<ci>J</ci>
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<minus/>
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<ci>S1</ci>
<ci>S2</ci>
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<ci>P1</ci>
<ci>P2</ci>
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<ci>J</ci>
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<variable name="J" public_interface="out" units="mM_per_second"/>
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<minus/>
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<ci>S1</ci>
<ci>S2</ci>
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<times/>
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<ci>P</ci>
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<minus/>
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<ci>S</ci>
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<ci>P2</ci>
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<variable name="J" public_interface="out" units="mM_per_second"/>
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<minus/>
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<variable name="S" public_interface="in" units="mM"/>
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<divide/>
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<ci>V</ci>
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<plus/>
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<ci>S</ci>
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<variable name="J" public_interface="out" units="mM_per_second"/>
<variable name="S" public_interface="in" units="mM"/>
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<ci>J</ci>
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<divide/>
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<minus/>
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<ci>Km_S</ci>
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<divide/>
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<plus/>
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<divide/>
<ci>P</ci>
<ci>Km_P</ci>
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<variable name="J" public_interface="out" units="mM_per_second"/>
<variable name="S" public_interface="in" units="mM"/>
<variable name="A" public_interface="in" units="mM"/>
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<variable name="Kac" public_interface="in" units="mM"/>
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<divide/>
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<times/>
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<ci>S</ci>
<ci>A</ci>
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<plus/>
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<ci>Km_S</ci>
<apply>
<plus/>
<ci>Kas</ci>
<ci>A</ci>
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<times/>
<ci>S</ci>
<apply>
<plus/>
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<apply>
<divide/>
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<times/>
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<minus/>
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<divide/>
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<ci>Km_S</ci>
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<divide/>
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<times/>
<ci>V_b</ci>
<ci>P</ci>
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<ci>Km_P</ci>
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<ci>A</ci>
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<plus/>
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<ci>A</ci>
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<times/>
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<plus/>
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<divide/>
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<ci>Km_S</ci>
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<divide/>
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<ci>Km_P</ci>
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<plus/>
<ci>Kac</ci>
<ci>A</ci>
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<variable name="J" public_interface="out" units="mM_per_second"/>
<variable name="S" public_interface="in" units="mM"/>
<variable name="I" public_interface="in" units="mM"/>
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<eq/>
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<divide/>
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<times/>
<ci>V</ci>
<ci>S</ci>
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<plus/>
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<times/>
<ci>Km_S</ci>
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<plus/>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
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<divide/>
<ci>I</ci>
<ci>Kis</ci>
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<times/>
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<plus/>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
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<divide/>
<ci>I</ci>
<ci>Kic</ci>
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<variable name="J" public_interface="out" units="mM_per_second"/>
<variable name="S" public_interface="in" units="mM"/>
<variable name="P" public_interface="in" units="mM"/>
<variable name="I" public_interface="in" units="mM"/>
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<variable name="Kis" public_interface="in" units="mM"/>
<variable name="Kic" public_interface="in" units="mM"/>
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<variable name="Km_P" public_interface="in" units="mM"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
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<eq/>
<ci>J</ci>
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<divide/>
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<minus/>
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<divide/>
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<times/>
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<ci>S</ci>
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<ci>Km_S</ci>
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<divide/>
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<times/>
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<ci>Km_P</ci>
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<plus/>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
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<divide/>
<ci>I</ci>
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<times/>
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<plus/>
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<divide/>
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<ci>Km_S</ci>
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<divide/>
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<plus/>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
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<divide/>
<ci>I</ci>
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<plus/>
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<divide/>
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<divide/>
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<minus/>
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<divide/>
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<plus/>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
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<divide/>
<ci>S</ci>
<ci>Km_S</ci>
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<divide/>
<ci>P</ci>
<ci>Km_P</ci>
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<plus/>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
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<divide/>
<ci>I</ci>
<ci>Ki</ci>
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<variable name="S1" public_interface="in" units="mM"/>
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<variable name="Keq" public_interface="in" units="dimensionless"/>
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<eq/>
<ci>J</ci>
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<divide/>
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<times/>
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<minus/>
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<times/>
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<divide/>
<apply>
<times/>
<ci>P1</ci>
<ci>P2</ci>
</apply>
<ci>Keq</ci>
</apply>
</apply>
</apply>
<apply>
<plus/>
<apply>
<times/>
<ci>S1</ci>
<ci>S2</ci>
<apply>
<plus/>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<ci>P1</ci>
<ci>Ki_P1</ci>
</apply>
</apply>
</apply>
<apply>
<times/>
<ci>Km_S1</ci>
<ci>S2</ci>
</apply>
<apply>
<times/>
<ci>Km_S2</ci>
<apply>
<plus/>
<ci>S1</ci>
<ci>Ki_S1</ci>
</apply>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci>V_f</ci>
<apply>
<times/>
<ci>V_b</ci>
<ci>Keq</ci>
</apply>
</apply>
<apply>
<plus/>
<apply>
<times/>
<ci>Km_P2</ci>
<ci>P1</ci>
<apply>
<plus/>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<ci>S1</ci>
<ci>Ki_S1</ci>
</apply>
</apply>
</apply>
<apply>
<times/>
<ci>P2</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>Km_P1</ci>
<apply>
<plus/>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<apply>
<times/>
<ci>Km_S1</ci>
<ci>S2</ci>
</apply>
<apply>
<times/>
<ci>Ki_S1</ci>
<ci>Km_S2</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<times/>
<ci>P1</ci>
<apply>
<plus/>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<ci>S2</ci>
<ci>Ki_S2</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</math>
</component><component xmlns="http://www.cellml.org/cellml/1.0#" name="OrderedBiUni">
<variable name="J" public_interface="out" units="mM_per_second"/>
<variable name="S1" public_interface="in" units="mM"/>
<variable name="S2" public_interface="in" units="mM"/>
<variable name="P" public_interface="in" units="mM"/>
<variable name="V_f" public_interface="in" units="mM_per_second"/>
<variable name="V_b" public_interface="in" units="mM_per_second"/>
<variable name="Keq" public_interface="in" units="per_mM"/>
<variable name="Km_S1" public_interface="in" units="mM"/>
<variable name="Km_S2" public_interface="in" units="mM"/>
<variable name="Km_P" public_interface="in" units="mM"/>
<variable name="Ki_S1" public_interface="in" units="mM"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>J</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>V_f</ci>
<apply>
<minus/>
<apply>
<times/>
<ci>S1</ci>
<ci>S2</ci>
</apply>
<apply>
<divide/>
<ci>P</ci>
<ci>Keq</ci>
</apply>
</apply>
</apply>
<apply>
<plus/>
<apply>
<times/>
<ci>S1</ci>
<ci>S2</ci>
</apply>
<apply>
<times/>
<ci>Km_S1</ci>
<ci>S2</ci>
</apply>
<apply>
<times/>
<ci>Km_S2</ci>
<ci>S1</ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci>V_f</ci>
<apply>
<times/>
<ci>V_b</ci>
<ci>Keq</ci>
</apply>
</apply>
<apply>
<plus/>
<ci>Km_P</ci>
<apply>
<times/>
<ci>P</ci>
<apply>
<plus/>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<ci>S1</ci>
<ci>Ki_S1</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</math>
</component><component xmlns="http://www.cellml.org/cellml/1.0#" name="OrderedUniBi">
<variable name="J" public_interface="out" units="mM_per_second"/>
<variable name="S" public_interface="in" units="mM"/>
<variable name="P1" public_interface="in" units="mM"/>
<variable name="P2" public_interface="in" units="mM"/>
<variable name="V_f" public_interface="in" units="mM_per_second"/>
<variable name="V_b" public_interface="in" units="mM_per_second"/>
<variable name="Keq" public_interface="in" units="mM"/>
<variable name="Km_S" public_interface="in" units="mM"/>
<variable name="Km_P1" public_interface="in" units="mM"/>
<variable name="Km_P2" public_interface="in" units="mM"/>
<variable name="Ki_P1" public_interface="in" units="mM"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>J</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>V_f</ci>
<apply>
<minus/>
<ci>S</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>P1</ci>
<ci>P2</ci>
</apply>
<ci>Keq</ci>
</apply>
</apply>
</apply>
<apply>
<plus/>
<ci>Km_S</ci>
<apply>
<times/>
<ci>S</ci>
<apply>
<plus/>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<ci>P1</ci>
<ci>Ki_P1</ci>
</apply>
</apply>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci>V_f</ci>
<apply>
<times/>
<ci>V_b</ci>
<ci>Keq</ci>
</apply>
</apply>
<apply>
<plus/>
<apply>
<times/>
<ci>Km_P2</ci>
<ci>P1</ci>
</apply>
<apply>
<times/>
<ci>Km_P1</ci>
<ci>P2</ci>
</apply>
<apply>
<times/>
<ci>P1</ci>
<ci>P2</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</math>
</component><component xmlns="http://www.cellml.org/cellml/1.0#" name="PingPongBiBi">
<variable name="J" public_interface="out" units="mM_per_second"/>
<variable name="S1" public_interface="in" units="mM"/>
<variable name="S2" public_interface="in" units="mM"/>
<variable name="P1" public_interface="in" units="mM"/>
<variable name="P2" public_interface="in" units="mM"/>
<variable name="V_f" public_interface="in" units="mM_per_second"/>
<variable name="V_b" public_interface="in" units="mM_per_second"/>
<variable name="Keq" public_interface="in" units="dimensionless"/>
<variable name="Km_S1" public_interface="in" units="mM"/>
<variable name="Km_S2" public_interface="in" units="mM"/>
<variable name="Km_P1" public_interface="in" units="mM"/>
<variable name="Km_P2" public_interface="in" units="mM"/>
<variable name="Ki_S1" public_interface="in" units="mM"/>
<variable name="Ki_P2" public_interface="in" units="mM"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>J</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>V_f</ci>
<apply>
<minus/>
<apply>
<times/>
<ci>S1</ci>
<ci>S2</ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci>P1</ci>
<ci>P2</ci>
</apply>
<ci>Keq</ci>
</apply>
</apply>
</apply>
<apply>
<plus/>
<apply>
<times/>
<ci>S1</ci>
<ci>S2</ci>
</apply>
<apply>
<times/>
<ci>Km_S2</ci>
<ci>S1</ci>
</apply>
<apply>
<times/>
<ci>Km_S1</ci>
<ci>S2</ci>
<apply>
<plus/>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<ci>P2</ci>
<ci>Ki_P2</ci>
</apply>
</apply>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci>V_f</ci>
<apply>
<times/>
<ci>V_b</ci>
<ci>Keq</ci>
</apply>
</apply>
<apply>
<plus/>
<apply>
<times/>
<ci>Km_P2</ci>
<ci>P1</ci>
<apply>
<plus/>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<ci>S1</ci>
<ci>Ki_S1</ci>
</apply>
</apply>
</apply>
<apply>
<times/>
<ci>P2</ci>
<apply>
<plus/>
<ci>Km_P1</ci>
<ci>P1</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</math>
</component><component xmlns="http://www.cellml.org/cellml/1.0#" name="SpecificActivationIrrev">
<variable name="J" public_interface="out" units="mM_per_second"/>
<variable name="S" public_interface="in" units="mM"/>
<variable name="A" public_interface="in" units="mM"/>
<variable name="V" public_interface="in" units="mM_per_second"/>
<variable name="Km_S" public_interface="in" units="mM"/>
<variable name="Km_A" public_interface="in" units="mM"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>J</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>V</ci>
<ci>S</ci>
<ci>A</ci>
</apply>
<apply>
<plus/>
<apply>
<times/>
<ci>Km_S</ci>
<ci>Km_A</ci>
</apply>
<apply>
<times/>
<apply>
<plus/>
<ci>Km_S</ci>
<ci>S</ci>
</apply>
<ci>A</ci>
</apply>
</apply>
</apply>
</apply>
</math>
</component><component xmlns="http://www.cellml.org/cellml/1.0#" name="SpecificActivationRev">
<variable name="J" public_interface="out" units="mM_per_second"/>
<variable name="S" public_interface="in" units="mM"/>
<variable name="P" public_interface="in" units="mM"/>
<variable name="A" public_interface="in" units="mM"/>
<variable name="V_f" public_interface="in" units="mM_per_second"/>
<variable name="V_b" public_interface="in" units="mM_per_second"/>
<variable name="Km_S" public_interface="in" units="mM"/>
<variable name="Km_P" public_interface="in" units="mM"/>
<variable name="Km_A" public_interface="in" units="mM"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>J</ci>
<apply>
<divide/>
<apply>
<times/>
<apply>
<minus/>
<apply>
<divide/>
<apply>
<times/>
<ci>V_f</ci>
<ci>S</ci>
</apply>
<ci>Km_S</ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci>V_b</ci>
<ci>P</ci>
</apply>
<ci>Km_P</ci>
</apply>
</apply>
<ci>A</ci>
</apply>
<apply>
<plus/>
<ci>Km_A</ci>
<apply>
<times/>
<apply>
<plus/>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<ci>S</ci>
<ci>Km_S</ci>
</apply>
<apply>
<divide/>
<ci>P</ci>
<ci>Km_P</ci>
</apply>
</apply>
<ci>A</ci>
</apply>
</apply>
</apply>
</apply>
</math>
</component><component xmlns="http://www.cellml.org/cellml/1.0#" name="SubstrateActivationIrrev">
<variable name="J" public_interface="out" units="mM_per_second"/>
<variable name="S" public_interface="in" units="mM"/>
<variable name="V" public_interface="in" units="mM_per_second"/>
<variable name="K_sa" public_interface="in" units="mM"/>
<variable name="K_sc" public_interface="in" units="mM"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>J</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>V</ci>
<apply>
<power/>
<apply>
<divide/>
<ci>S</ci>
<ci>K_sa</ci>
</apply>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">2</cn>
</apply>
</apply>
<apply>
<plus/>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<ci>S</ci>
<ci>K_sc</ci>
</apply>
<apply>
<divide/>
<ci>S</ci>
<ci>K_sa</ci>
</apply>
<apply>
<power/>
<apply>
<divide/>
<ci>S</ci>
<ci>K_sa</ci>
</apply>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">2</cn>
</apply>
</apply>
</apply>
</apply>
</math>
</component><component xmlns="http://www.cellml.org/cellml/1.0#" name="SubstrateInhibitionIrrev">
<variable name="J" public_interface="out" units="mM_per_second"/>
<variable name="S" public_interface="in" units="mM"/>
<variable name="V" public_interface="in" units="mM_per_second"/>
<variable name="I" public_interface="in" units="mM"/>
<variable name="Km_S" public_interface="in" units="mM"/>
<variable name="Ki" public_interface="in" units="mM"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>J</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>V</ci>
<ci>S</ci>
</apply>
<apply>
<plus/>
<ci>Km_S</ci>
<ci>S</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>Km_S</ci>
<apply>
<power/>
<ci>S</ci>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">2</cn>
</apply>
</apply>
<apply>
<power/>
<ci>Ki</ci>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">2</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</math>
</component><component xmlns="http://www.cellml.org/cellml/1.0#" name="SubstrateInhibitionRev">
<variable name="J" public_interface="out" units="mM_per_second"/>
<variable name="S" public_interface="in" units="mM"/>
<variable name="P" public_interface="in" units="mM"/>
<variable name="V_f" public_interface="in" units="mM_per_second"/>
<variable name="V_b" public_interface="in" units="mM_per_second"/>
<variable name="Km_S" public_interface="in" units="mM"/>
<variable name="Km_P" public_interface="in" units="mM"/>
<variable name="Ki" public_interface="in" units="mM"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>J</ci>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<divide/>
<apply>
<times/>
<ci>V_f</ci>
<ci>S</ci>
</apply>
<ci>Km_S</ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci>V_b</ci>
<ci>P</ci>
</apply>
<ci>Km_P</ci>
</apply>
</apply>
<apply>
<plus/>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<ci>S</ci>
<ci>Km_S</ci>
</apply>
<apply>
<divide/>
<ci>P</ci>
<ci>Km_P</ci>
</apply>
<apply>
<divide/>
<apply>
<power/>
<ci>S</ci>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">2</cn>
</apply>
<apply>
<power/>
<ci>Ki</ci>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">2</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</math>
</component><component xmlns="http://www.cellml.org/cellml/1.0#" name="UncompetitiveInhibitionIrrev">
<variable name="J" public_interface="out" units="mM_per_second"/>
<variable name="S" public_interface="in" units="mM"/>
<variable name="V" public_interface="in" units="mM_per_second"/>
<variable name="I" public_interface="in" units="mM"/>
<variable name="Km_S" public_interface="in" units="mM"/>
<variable name="K_I" public_interface="in" units="mM"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>J</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>V</ci>
<ci>S</ci>
</apply>
<apply>
<plus/>
<ci>Km_S</ci>
<apply>
<times/>
<ci>S</ci>
<apply>
<plus/>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<ci>I</ci>
<ci>K_I</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</math>
</component></model>
