Location: semantic-annotation @ 0eebe1382a2c / blood_capillary_flux.cellml

Author:
Dewan Sarwar <dsar941@UoA.auckland.ac.nz>
Date:
2019-11-21 18:27:30+13:00
Desc:
Modified SEDML models of three prototype protocols and their RDFs
Permanent Source URI:
https://models.cellml.org/workspace/267/rawfile/0eebe1382a2cc14b1a897d70fe4e1e739cce1a4c/blood_capillary_flux.cellml

<?xml version="1.0" encoding="UTF-8"?>
<model xmlns="http://www.cellml.org/cellml/1.1#" xmlns:cmeta="http://www.cellml.org/metadata/1.0#" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bqs="http://www.cellml.org/bqs/1.0#" xmlns:semsim="http://www.bhi.washington.edu/SemSim#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" name="blood_capillary_flux" cmeta:id="blood_capillary_flux">
  <units name="mM">
    <unit prefix="milli" units="mole" />
    <unit exponent="-1.0" units="litre" />
  </units>
  <units name="flux">
    <unit exponent="-3.0" prefix="centi" units="metre" />
    <unit exponent="-1.0" units="second" />
    <unit prefix="milli" units="mole" />
  </units>
  <units name="millisec">
    <unit prefix="milli" units="second" />
  </units>
  <units name="per_millisec">
    <unit exponent="-1.0" prefix="milli" units="second" />
  </units>
  <component name="environment">
    <variable cmeta:id="environment.time" name="time" public_interface="out" units="second" />
  </component>
  <component name="blood_capillary_flux">
    <variable cmeta:id="blood_capillary_flux.C_ts_Na" name="C_ts_Na" public_interface="in" units="mM" />
    <variable cmeta:id="blood_capillary_flux.C_Na" name="C_Na" public_interface="in" units="mM" />
    <variable cmeta:id="blood_capillary_flux.C_ts_Cl" name="C_ts_Cl" public_interface="in" units="mM" />
    <variable cmeta:id="blood_capillary_flux.C_Cl" name="C_Cl" public_interface="in" units="mM" />
    <variable cmeta:id="blood_capillary_flux.G_Na" name="G_Na" public_interface="in" units="flux" />
    <variable cmeta:id="blood_capillary_flux.J_Cl" name="J_Cl" public_interface="in" units="flux" />
    <variable cmeta:id="blood_capillary_flux.C_K" initial_value="140" name="C_K" public_interface="out" units="mM" />
  </component>
  <rdf:RDF xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:ro="http://www.obofoundry.org/ro/ro.owl#" xmlns:opb="http://bhi.washington.edu/OPB#">
    <rdf:Description rdf:about="">
      <dc:title>HH sodium ion channel model</dc:title>
    </rdf:Description>
    <rdf:Description rdf:about="#blood_capillary_flux.C_ts_Na">
      <semsim:isComputationalComponentFor>
        <rdf:Description rdf:about="#property_0">
          <semsim:physicalPropertyOf>
            <rdf:Description rdf:about="#entity_0">
              <ro:part_of>
                <rdf:Description rdf:about="#entity_1">
                  <ro:part_of>
                    <rdf:Description rdf:about="#entity_2">
                      <semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_70981" />
                    </rdf:Description>
                  </ro:part_of>
                  <semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_9673" />
                </rdf:Description>
              </ro:part_of>
              <semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/CHEBI_29101" />
            </rdf:Description>
          </semsim:physicalPropertyOf>
          <semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00340" />
        </rdf:Description>
      </semsim:isComputationalComponentFor>
      <dcterms:description>concentration of sodium in the portion of tissue fluid in the epithelial cell of distal tubule compartment</dcterms:description>
    </rdf:Description>
    <rdf:Description rdf:about="#blood_capillary_flux" semsim:unknown="blood_capillary_flux" semsim:modelName="blood_capillary_flux">
      <ro:modelOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000066" />
      <ro:located_in rdf:resource="http://purl.obolibrary.org/obo/FMA_17721" />
      <ro:compartmentOf rdf:resource="http://purl.obolibrary.org/obo/FMA_263901" />
    </rdf:Description>
    <rdf:Description rdf:about="#model">
      <bqs:reference rdf:parseType="Resource">
        <dc:subject rdf:parseType="Resource">
          <bqs:subject_type>keyword</bqs:subject_type>
          <rdf:value>
            <rdf:Bag>
              <rdf:li>protein module</rdf:li>
            </rdf:Bag>
          </rdf:value>
        </dc:subject>
      </bqs:reference>
    </rdf:Description>
    <rdf:Description rdf:about="#blood_capillary_flux.C_ts_Cl">
      <semsim:isComputationalComponentFor>
        <rdf:Description rdf:about="#property_2">
          <semsim:physicalPropertyOf>
            <rdf:Description rdf:about="#entity_5">
              <ro:part_of rdf:resource="#entity_1" />
              <semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/CHEBI_17996" />
            </rdf:Description>
          </semsim:physicalPropertyOf>
          <semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00340" />
        </rdf:Description>
      </semsim:isComputationalComponentFor>
      <dcterms:description>concentration of chloride in the portion of tissue fluid in the epithelial cell of distal tubule compartment</dcterms:description>
    </rdf:Description>
    <rdf:Description rdf:about="#blood_capillary_flux.G_Na">
      <semsim:isComputationalComponentFor>
        <rdf:Description rdf:about="#property_4">
          <semsim:physicalPropertyOf>
            <rdf:Description rdf:about="#process_0" dcterms:description="">
              <semsim:hasMediatorParticipant>
                <rdf:Description rdf:about="#mediator_0">
                  <semsim:hasPhysicalEntityReference>
                    <rdf:Description rdf:about="#entity_7">
                      <ro:part_of>
                        <rdf:Description rdf:about="#entity_8">
                          <ro:part_of rdf:resource="#entity_2" />
                          <semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_63194" />
                        </rdf:Description>
                      </ro:part_of>
                      <semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/PR_000014527" />
                    </rdf:Description>
                  </semsim:hasPhysicalEntityReference>
                </rdf:Description>
              </semsim:hasMediatorParticipant>
              <semsim:hasSinkParticipant>
                <rdf:Description rdf:about="#sink_0" semsim:hasMultiplier="1.0">
                  <semsim:hasPhysicalEntityReference>
                    <rdf:Description rdf:about="#entity_3">
                      <ro:part_of>
                        <rdf:Description rdf:about="#entity_4">
                          <ro:part_of rdf:resource="#entity_2" />
                          <semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_263901" />
                        </rdf:Description>
                      </ro:part_of>
                      <semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/CHEBI_29101" />
                    </rdf:Description>
                  </semsim:hasPhysicalEntityReference>
                </rdf:Description>
              </semsim:hasSinkParticipant>
              <semsim:hasSourceParticipant>
                <rdf:Description rdf:about="#source_0" semsim:hasMultiplier="1.0">
                  <semsim:hasPhysicalEntityReference rdf:resource="#entity_0" />
                </rdf:Description>
              </semsim:hasSourceParticipant>
              <semsim:name>Na+ flow through amiloride-sensitive sodium channel subunit alpha</semsim:name>
            </rdf:Description>
          </semsim:physicalPropertyOf>
          <semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00593" />
        </rdf:Description>
      </semsim:isComputationalComponentFor>
      <dcterms:description>Flux of sodium from portion of tissue fluid in the epithelial cell of distal tubule to portion of blood in capillary in the epithelial cell of distal tubule through amiloride-sensitive sodium channel subunit alpha</dcterms:description>
    </rdf:Description>
    <rdf:Description rdf:about="#blood_capillary_flux.C_Cl">
      <semsim:isComputationalComponentFor>
        <rdf:Description rdf:about="#property_3">
          <semsim:physicalPropertyOf>
            <rdf:Description rdf:about="#entity_6">
              <ro:part_of rdf:resource="#entity_4" />
              <semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/CHEBI_17996" />
            </rdf:Description>
          </semsim:physicalPropertyOf>
          <semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00340" />
        </rdf:Description>
      </semsim:isComputationalComponentFor>
      <dcterms:description>concentration of chloride in the portion of blood in capillary in the epithelial cell of distal tubule compartment</dcterms:description>
    </rdf:Description>
    <rdf:Description rdf:about="#blood_capillary_flux.J_Cl">
      <semsim:isComputationalComponentFor>
        <rdf:Description rdf:about="#property_5">
          <semsim:physicalPropertyOf>
            <rdf:Description rdf:about="#process_1" dcterms:description="">
              <semsim:hasMediatorParticipant>
                <rdf:Description rdf:about="#mediator_1">
                  <semsim:hasPhysicalEntityReference>
                    <rdf:Description rdf:about="#entity_10">
                      <ro:part_of rdf:resource="#entity_8" />
                      <semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/PR_000001873" />
                    </rdf:Description>
                  </semsim:hasPhysicalEntityReference>
                </rdf:Description>
              </semsim:hasMediatorParticipant>
              <semsim:hasSinkParticipant>
                <rdf:Description rdf:about="#sink_1" semsim:hasMultiplier="1.0">
                  <semsim:hasPhysicalEntityReference rdf:resource="#entity_6" />
                </rdf:Description>
              </semsim:hasSinkParticipant>
              <semsim:hasSourceParticipant>
                <rdf:Description rdf:about="#source_1" semsim:hasMultiplier="1.0">
                  <semsim:hasPhysicalEntityReference rdf:resource="#entity_5" />
                </rdf:Description>
              </semsim:hasSourceParticipant>
              <semsim:name>Cl- flow through kell blood group glycoprotein</semsim:name>
            </rdf:Description>
          </semsim:physicalPropertyOf>
          <semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00593" />
        </rdf:Description>
      </semsim:isComputationalComponentFor>
      <dcterms:description>Flux of chloride from portion of tissue fluid in the epithelial cell of distal tubule to portion of blood in capillary in the epithelial cell of distal tubule through kell blood group glycoprotein</dcterms:description>
    </rdf:Description>
    <rdf:Description rdf:about="#environment.time" dcterms:description="Time">
      <bqbiol:is rdf:resource="http://identifiers.org/opb/OPB_01023" />
    </rdf:Description>
    <rdf:Description rdf:about="#blood_capillary_flux.C_Na">
      <semsim:isComputationalComponentFor>
        <rdf:Description rdf:about="#property_1">
          <semsim:physicalPropertyOf rdf:resource="#entity_3" />
          <semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00340" />
        </rdf:Description>
      </semsim:isComputationalComponentFor>
      <dcterms:description>concentration of sodium in the portion of blood in capillary in the epithelial cell of distal tubule compartment</dcterms:description>
    </rdf:Description>
    <rdf:Description rdf:about="#blood_capillary_flux.C_K">
      <semsim:isComputationalComponentFor>
        <rdf:Description rdf:about="#property_6">
          <semsim:physicalPropertyOf>
            <rdf:Description rdf:about="#entity_9">
              <ro:part_of rdf:resource="#entity_4" />
              <semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/CHEBI_29103" />
            </rdf:Description>
          </semsim:physicalPropertyOf>
          <semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00340" />
        </rdf:Description>
      </semsim:isComputationalComponentFor>
      <dcterms:description>Concentration of potassium in the portion of blood in capillary in the epithelial cell of distal tubule tubule</dcterms:description>
    </rdf:Description>
  </rdf:RDF>
</model>