- Author:
- Dewan Sarwar <dsar941@UoA.auckland.ac.nz>
- Date:
- 2020-04-16 16:07:00+12:00
- Desc:
- added protocol 1I and 1J
- Permanent Source URI:
- https://models.cellml.org/workspace/267/rawfile/f4cbce4b1abfdb513e9a99528bac6eca57eaa39b/NaKATPase/NaK_test.cellml
<?xml version="1.0" encoding="UTF-8"?>
<model xmlns="http://www.cellml.org/cellml/1.1#" xmlns:cmeta="http://www.cellml.org/metadata/1.0#" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bqs="http://www.cellml.org/bqs/1.0#" xmlns:semsim="http://www.bhi.washington.edu/SemSim#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" name="Strieter_1992_NaK" cmeta:id="Strieter_1992_NaK">
<import xlink:href="Units/Units.cellml">
<units name="mA_per_cm2" units_ref="mA_per_cm2" />
</import>
<import xlink:href="Units/Units.cellml">
<units name="mM" units_ref="mM" />
</import>
<import xlink:href="Strieter_1992_NaK.cellml">
<component name="NaK" component_ref="NaK" />
</import>
<import xlink:href="Units/Units.cellml">
<units name="umol_per_s_per_cm2" units_ref="umol_per_s_per_cm2" />
</import>
<import xlink:href="Units/Units.cellml">
<units name="mV" units_ref="mV" />
</import>
<import xlink:href="Units/Units.cellml">
<units name="mM_per_s" units_ref="mM_per_s" />
</import>
<component name="environment">
<variable cmeta:id="environment.time" name="time" public_interface="out" units="second" />
</component>
<component name="concentrations">
<variable cmeta:id="concentrations.time" name="time" public_interface="in" units="second" />
<variable cmeta:id="concentrations.V" initial_value="-150.0" name="V" public_interface="out" units="mV" />
<variable cmeta:id="concentrations.Na_int" initial_value="10.0" name="Na_int" public_interface="out" units="mM" />
<variable cmeta:id="concentrations.Na_ext" initial_value="0.001" name="Na_ext" public_interface="out" units="mM" />
<variable cmeta:id="concentrations.K_int" initial_value="0.001" name="K_int" public_interface="out" units="mM" />
<variable cmeta:id="concentrations.K_ext" initial_value="50.0" name="K_ext" public_interface="out" units="mM" />
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq />
<apply>
<diff />
<bvar>
<ci>time</ci>
</bvar>
<ci>Na_int</ci>
</apply>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.1#" cellml:units="mM_per_s">1</cn>
</apply>
</math>
</component>
<component name="fluxes">
<variable cmeta:id="fluxes.J_NaK" name="J_NaK" public_interface="in" units="dimensionless" />
<variable cmeta:id="fluxes.J_NaK_max" initial_value="0.0108" name="J_NaK_max" public_interface="out" units="umol_per_s_per_cm2" />
<variable cmeta:id="fluxes.I_NaK" name="I_NaK" public_interface="in" units="mA_per_cm2" />
</component>
<connection>
<map_components component_1="environment" component_2="concentrations" />
<map_variables variable_1="time" variable_2="time" />
</connection>
<connection>
<map_components component_1="concentrations" component_2="NaK" />
<map_variables variable_1="K_int" variable_2="K_int" />
<map_variables variable_1="Na_ext" variable_2="Na_ext" />
<map_variables variable_1="K_ext" variable_2="K_ext" />
<map_variables variable_1="V" variable_2="V" />
<map_variables variable_1="Na_int" variable_2="Na_int" />
</connection>
<connection>
<map_components component_1="NaK" component_2="fluxes" />
<map_variables variable_1="I_NaK" variable_2="I_NaK" />
<map_variables variable_1="J_NaK" variable_2="J_NaK" />
</connection>
<connection>
<map_components component_1="fluxes" component_2="NaK" />
<map_variables variable_1="J_NaK_max" variable_2="J_NaK_max" />
</connection>
<rdf:RDF xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:ro="http://www.obofoundry.org/ro/ro.owl#" xmlns:opb="http://bhi.washington.edu/OPB#" xmlns:j.0="http://imc.org/vCard/3.0#">
<rdf:Description rdf:about="">
<dc:creator rdf:parseType="Resource">
<vCard:N vCard:Family="Terkildsen" vCard:Given="Jonna" />
<vCard:EMAIL rdf:value="j.terkildsen@auckland.ac.nz" rdf:type="http://imc.org/vCard/3.0#internet" />
<vCard:ORG rdf:parseType="Resource">
<vCard:Orgname>Auckland Bioengineering Institute</vCard:Orgname>
</vCard:ORG>
</dc:creator>
<dcterms:created dcterms:W3CDTF="2009-11-11" />
</rdf:Description>
<rdf:Description rdf:about="#weinstein_2000_AE1">
<dc:title>The Weinstein 2000 quantitative model of AE1 (Cl/HCO3 exchanger).</dc:title>
<cmeta:comment rdf:parseType="Resource">
<rdf:value>This is the CellML description of the Weinstein 2000 quantitative model of AE1 (Cl/HCO3 exchanger)</rdf:value>
<dc:creator rdf:parseType="Resource">
<vCard:FN>Jonna Terkildsen</vCard:FN>
</dc:creator>
</cmeta:comment>
<bqs:reference rdf:parseType="Resource">
<dc:subject rdf:parseType="Resource">
<bqs:subject_type>keyword</bqs:subject_type>
<rdf:value>
<rdf:Bag>
<rdf:li>renal</rdf:li>
<rdf:li>ion transport</rdf:li>
<rdf:li>kidney</rdf:li>
<rdf:li>medullary collecting duct</rdf:li>
</rdf:Bag>
</rdf:value>
</dc:subject>
</bqs:reference>
<bqs:reference rdf:parseType="Resource">
<bqs:Pubmed_id>10894785</bqs:Pubmed_id>
<bqs:JournalArticle rdf:parseType="Resource">
<dc:creator>
<rdf:Seq>
<rdf:li rdf:parseType="Resource">
<bqs:Person rdf:parseType="Resource">
<vCard:N vCard:Family="Weinstein" vCard:Given="A" vCard:Other="M" />
</bqs:Person>
</rdf:li>
</rdf:Seq>
</dc:creator>
<dc:title>A mathematical model of the outer medullary collecting duct of the rat</dc:title>
<dcterms:issued dcterms:W3CDTF="2000-07" />
<bqs:Journal rdf:parseType="Resource">
<dc:title>American Journal of Physiology</dc:title>
</bqs:Journal>
<bqs:volume>279</bqs:volume>
<bqs:first_page>24</bqs:first_page>
<bqs:last_page>45</bqs:last_page>
</bqs:JournalArticle>
</bqs:reference>
</rdf:Description>
<rdf:Description rdf:about="#Strieter_1992_NaK" semsim:PubMedIDofReferencePublication="10894785" semsim:modelId="Strieter_1992_NaK" semsim:modelName="Strieter_1992_NaK" />
</rdf:RDF>
</model>
