Location: Na+/H+ Exchanger @ 1c123cd4c24a / documentation-fig2.html

Soroush Safaei <ssaf006@aucklanduni.ac.nz>
2017-06-08 19:07:35+12:00
adding the bg diagrams
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Figure 2

This is the general mathematical model for the NHE3 model with modifications to enable simulations which are capable of reproducing Figure 2 in the original paper. The simulation experiment for this model can be obtained by loading the corresponding SED-ML document into OpenCOR and executing the simulation. The results of which are shown below. A rendering of the mathematical model itself is available here.

In Figure 2, the Na+ influx is computed for a range of external pH when NH4+ is not present. Internal and external Na+ concentrations are fixed at 0.0 and 0.1 mM; internal pH is 6; and external pH is varied from 6 to 8. (top) Na+ flux is shown as a function of the external pH. (bottom) Reciprocal flux is shown as a function of the external H+ concentration.

A screenshot illustrating the results when the associated SED-ML document is loaded into OpenCOR and the simulation executed.

This can be reproduced directly from the repository by choosing the Launch with OpenCOR link from the Views Available.