# Location: Na+/H+ Exchanger @ 7b31eb3e8a44 / documentation-fig2.html

- Author:
- Soroush Safaei <ssaf006@aucklanduni.ac.nz>
- Date:
- 2016-05-12 17:27:44+12:00
- Desc:
- fix the links
- Permanent Source URI:
- https://models.cellml.org/workspace/28f/rawfile/7b31eb3e8a447b4a7eccd7e99815258059f0a8bb/documentation-fig2.html

#### Figure 2

This is the general mathematical model for the NHE3 model with modifications to enable simulations which are capable of reproducing Figure 2 in the original paper. The simulation experiment for this model can be obtained by loading the corresponding SED-ML document into OpenCOR and executing the simulation. The results of which are shown below. A rendering of the mathematical model itself is available here.

In Figure 2, the Na^{+} influx is computed for a range of external pH when NH_{4}^{+} is not present. Internal and external Na^{+} concentrations are fixed at 0.0 and 0.1 mM; internal pH is 6; and external pH is varied from 6 to 8. (*top*) Na^{+} flux is shown as a function of the external pH. (*bottom*) Reciprocal flux is shown as a function of the external H^{+} concentration.

A screenshot illustrating the results when the associated SED-ML document is loaded into OpenCOR and the simulation executed.

This can be reproduced directly from the repository by choosing the **Launch with OpenCOR** link from the *Views Available*.