- Author:
- Michael Cooling <mcoo001@UoA.auckland.ac.nz>
- Date:
- 2016-04-11 11:48:36+12:00
- Desc:
- Initial Commit
- Permanent Source URI:
- https://models.cellml.org/workspace/2c5/rawfile/e8b0e5d10f563c9a997626435bace472ab5f7f34/Calcineurin_Activation.cellml
<?xml version="1.0" encoding="utf-8"?>
<model xmlns:xlink="http://www.w3.org/1999/xlink" name="Calcineurin_Activation" cmeta:id="Calcineurin_Activation"
xmlns="http://www.cellml.org/cellml/1.1#" xmlns:cellml="http://www.cellml.org/cellml/1.1#" xmlns:cmeta="http://www.cellml.org/metadata/1.0#">
<import xmlns="http://www.cellml.org/cellml/1.1#" xlink:href="Principled_Base/Units_Cellular_Systems.cellml">
<units name="nM" units_ref="nM"/>
<units name="nM_per_s" units_ref="nM_per_s"/>
</import>
<component name="Calcineurin_Activation_Parameters">
<variable name="M" units="nM" public_interface="out" initial_value="20500"/>
<variable name="K_mN" units="nM" public_interface="out" initial_value="535"/>
<variable name="n" units="dimensionless" public_interface="out" initial_value="2.92"/>
<variable name="K_dN" units="nM" public_interface="out" initial_value="1760"/>
<variable name="Ca" units="nM" public_interface="out" initial_value="500"/>
</component>
<component name="Calcineurin_Activation">
<variable name="Ca" units="nM" public_interface="in"/>
<variable name="M" units="nM" public_interface="in"/>
<variable name="K_mN" units="nM" public_interface="in"/>
<variable name="n" units="dimensionless" public_interface="in"/>
<variable name="K_dN" units="nM" public_interface="in"/>
<variable name="act_N" units="dimensionless" public_interface="out"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>act_N</ci>
<apply>
<divide/>
<apply>
<power/>
<ci>Ca</ci>
<ci>n</ci>
</apply>
<apply>
<plus/>
<apply>
<power/>
<ci>Ca</ci>
<ci>n</ci>
</apply>
<apply>
<times/>
<apply>
<power/>
<ci>K_mN</ci>
<ci>n</ci>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<ci>K_dN</ci>
<ci>M</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</math>
</component>
<connection>
<map_components component_1="Calcineurin_Activation" component_2="Calcineurin_Activation_Parameters"/>
<map_variables variable_1="M" variable_2="M"/>
<map_variables variable_1="K_mN" variable_2="K_mN"/>
<map_variables variable_1="n" variable_2="n"/>
<map_variables variable_1="K_dN" variable_2="K_dN"/>
<map_variables variable_1="Ca" variable_2="Ca"/>
</connection>
</model>
