- Author:
- David Nickerson <nickerso@users.sourceforge.net>
- Date:
- 2018-04-19 18:07:33-07:00
- Desc:
- updating model and annotations and adding COMBINE archive manifest file
- Permanent Source URI:
- https://models.cellml.org/workspace/4e3/rawfile/a7769367b201788d9ea33ddc1f6ffa8554611cb6/model/Kapela.rdf
<rdf:RDF
xmlns:dcterms="http://purl.org/dc/terms/"
xmlns:semsim="http://www.bhi.washington.edu/SemSim#"
xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" >
<rdf:Description rdf:about="./Kapela.cellml#K_e">
<bqbiol:isPropertyOf rdf:resource="./Kapela.cellml#entity_7"/>
<bqbiol:isVersionOf rdf:resource="http://bhi.washington.edu/OPB#OPB_00340"/>
<dcterms:description>Extracellular potassium concentration</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#PIP2">
<bqbiol:isPropertyOf rdf:resource="./Kapela.cellml#entity_29"/>
<bqbiol:isVersionOf rdf:resource="http://bhi.washington.edu/OPB#OPB_01001"/>
<dcterms:description>Number of cytosolic phosphatidylinositol 4,5-bisphosphate molecules</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#r_hG">
<dcterms:description>Inositol trisphosphate and PIP2 baseline production rate factor</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#entity_38">
<bqbiol:is rdf:resource="http://identifiers.org/chebi/CHEBI:30120"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#entity_26">
<bqbiol:isPartOf rdf:resource="./Kapela.cellml#entity_10"/>
<bqbiol:is rdf:resource="http://identifiers.org/chebi/CHEBI:29108"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#entity_14">
<bqbiol:isPartOf rdf:resource="./Kapela.cellml#entity_3"/>
<semsim:name>Portion of the cytosol available to calcium</semsim:name>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#C_m">
<bqbiol:isPropertyOf rdf:resource="./Kapela.cellml#entity_18"/>
<bqbiol:isVersionOf rdf:resource="http://bhi.washington.edu/OPB#OPB_00446"/>
<dcterms:description>Total membrane capacitance</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#sink_16">
<semsim:hasMultiplier>1.0</semsim:hasMultiplier>
<semsim:hasPhysicalEntityReference rdf:resource="./Kapela.cellml#entity_26"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#tau_pK">
<dcterms:description>Voltage gated potassium channel activaton gate time constant</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#rho_rG">
<dcterms:description>Alpha adrenoceptors norepinephrine sensitivity factor</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#Ca_r0">
<dcterms:description>Intitial sarcoplasmic reticulum release space calcium concentration</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#P_SOC0">
<dcterms:description>Initial store operated cation channel activation gate open probability</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#G_0">
<dcterms:description>Initial number of active G proteins</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#dV_50KCaNO">
<dcterms:description>Large conductance calcium activated potassium channel maximal NO independent voltage shift at 50% response</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#source_13">
<semsim:hasMultiplier>1.0</semsim:hasMultiplier>
<semsim:hasPhysicalEntityReference rdf:resource="./Kapela.cellml#entity_4"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#k_pG">
<dcterms:description>Alpha adrenoceptor phosphorylation rate</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#Ca_r">
<bqbiol:isPropertyOf rdf:resource="./Kapela.cellml#entity_10"/>
<bqbiol:isVersionOf rdf:resource="http://bhi.washington.edu/OPB#OPB_00340"/>
<dcterms:description>Sarcoplasmic reticulum release space calcium concentration</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#K_inhIP3">
<dcterms:description>IP3 receptor calcium inhibition dissociation constant</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#deltaG_0">
<dcterms:description>Alpha adrentoceptor tatio of activated unbound ligand</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#Vol_i">
<bqbiol:isPropertyOf rdf:resource="./Kapela.cellml#entity_37"/>
<bqbiol:isVersionOf rdf:resource="http://bhi.washington.edu/OPB#OPB_00154"/>
<dcterms:description>Total cytosolic volume</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#k_3sGC">
<dcterms:description>Soluble guanylate cyclase activation and cyclic GMP formation rate constant</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#entity_39">
<bqbiol:isPartOf rdf:resource="./Kapela.cellml#entity_16"/>
<semsim:name>Potassium leak channel</semsim:name>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#entity_27">
<bqbiol:isPartOf rdf:resource="./Kapela.cellml#entity_8"/>
<bqbiol:is rdf:resource="http://identifiers.org/chebi/CHEBI:33569"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#source_12">
<semsim:hasMultiplier>1.0</semsim:hasMultiplier>
<semsim:hasPhysicalEntityReference rdf:resource="./Kapela.cellml#entity_26"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#entity_15">
<bqbiol:isPartOf rdf:resource="./Kapela.cellml#entity_16"/>
<semsim:name>Store operated cation channel</semsim:name>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#INa_NaKCl">
<dcterms:description>Total cell sodium/potassium/chloride cotransporter sodium current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#P_BKCa">
<dcterms:description>Large conductance calcium activated potassium channel permeability surface area product</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#pbar_o">
<dcterms:description>Voltage gated potassium channel fast and slow activation gate steady state open probability</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#I_NaK">
<bqbiol:isPropertyOf rdf:resource="./Kapela.cellml#process_5"/>
<bqbiol:isVersionOf rdf:resource="http://bhi.washington.edu/OPB#OPB_00318"/>
<dcterms:description>Total cell sodium/potassium ATPase current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#q_2">
<dcterms:description>Voltage gated potassium channel slow activation gate open probability</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#sink_17">
<semsim:hasMultiplier>1.0</semsim:hasMultiplier>
<semsim:hasPhysicalEntityReference rdf:resource="./Kapela.cellml#entity_13"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#K_mr2">
<dcterms:description>Sarcoplasmic reticulum ryanodine receptor rate of calcium unbinding from inactivation site</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#K_dB">
<dcterms:description>Nonspecific calcium buffer dissociation constant</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#Ibar_PMCA">
<dcterms:description>Total cell plasma membrane calcium ATPase maximal calcium current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#i_KCa">
<dcterms:description>Single channel large conductance calcium activated potassium channel current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#Po_NSC">
<dcterms:description>Nonselective cation channel activation gate steady state open probability</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#R_100">
<dcterms:description>Initial ryanodine receptor state with calcium bound to the activation site</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#I_rel">
<bqbiol:isPropertyOf rdf:resource="./Kapela.cellml#process_8"/>
<bqbiol:isVersionOf rdf:resource="http://bhi.washington.edu/OPB#OPB_00318"/>
<dcterms:description>Total cell ryanodine receptor calcium current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#n_ClCa">
<dcterms:description>Calcium activated chloride channel calcium sensitivity Hill coefficient</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#Ibar_NaK">
<dcterms:description>Total cell sodium/potassium ATPase maximal current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#PIP2_0">
<dcterms:description>Initial number of cytosolic phosphatidylinositol 4,5-bisphosphate molecules</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#I_VOCC">
<bqbiol:isPropertyOf rdf:resource="./Kapela.cellml#process_12"/>
<bqbiol:isVersionOf rdf:resource="http://bhi.washington.edu/OPB#OPB_00318"/>
<dcterms:description>Total cell L-type calcium channel current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#n_HKe">
<dcterms:description>Sodium/potassium ATPase extracellular potassium Hill coefficient</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#K_ClCa">
<dcterms:description>Calcium activated chloride channel calcium activation effective concentration at 50% maximal response</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#tau_tr">
<dcterms:description>Sarcoplasmic reticulum internal rate of diffusion of calcium between uptake an release compartments</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#pbar_K">
<dcterms:description>Voltage gated potassium channel activation gate steady state open probability</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#entity_28">
<bqbiol:isPartOf rdf:resource="./Kapela.cellml#entity_20"/>
<bqbiol:is rdf:resource="http://identifiers.org/fma/FMA:72448"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#Cl_i0">
<dcterms:description>Initial intracellular chloride concentration</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#entity_16">
<bqbiol:isPartOf rdf:resource="./Kapela.cellml#entity_3"/>
<bqbiol:is rdf:resource="http://identifiers.org/fma/FMA:63841"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#ICa_totm">
<dcterms:description>Total cell plasma membrane calcium current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#sink_14">
<semsim:hasMultiplier>3.0</semsim:hasMultiplier>
<semsim:hasPhysicalEntityReference rdf:resource="./Kapela.cellml#entity_12"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#Ca_i0">
<dcterms:description>Initial intracellular calcium concentraion</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#process_0">
<semsim:hasSinkParticipant rdf:resource="./Kapela.cellml#sink_0"/>
<semsim:hasSourceParticipant rdf:resource="./Kapela.cellml#source_0"/>
<dcterms:description>Total cell sarcoplasmic/endoplamic reticulum calcium APTase current</dcterms:description>
<semsim:name>Sarcoplasmic/endoplamic reticulum calcium APTase current</semsim:name>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#z_K">
<dcterms:description>Valence of potassium</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#g_ClCa">
<bqbiol:isPropertyOf rdf:resource="./Kapela.cellml#entity_34"/>
<bqbiol:isVersionOf rdf:resource="http://bhi.washington.edu/OPB#OPB_00015"/>
<dcterms:description>Calcium activated chloride channel maximal conductance</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#ICl_totm">
<dcterms:description>Total cell plasma membrane chloride current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#d_L">
<dcterms:description>L-type calcium channel activation gate probability</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#source_15">
<semsim:hasMultiplier>3.0</semsim:hasMultiplier>
<semsim:hasPhysicalEntityReference rdf:resource="./Kapela.cellml#entity_11"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#alpha_Cl">
<dcterms:description>Ca-act Cl channel cGMP sensitivity term</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#V_cGMP">
<dcterms:description>Reaction velocity of cyclic GMP formation</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#R_supSPG0">
<dcterms:description>Initial number of phosporylated alpha adrenoreceptors</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#sink_0">
<semsim:hasMultiplier>1.0</semsim:hasMultiplier>
<semsim:hasPhysicalEntityReference rdf:resource="./Kapela.cellml#entity_4"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#entity_29">
<bqbiol:isPartOf rdf:resource="./Kapela.cellml#entity_5"/>
<bqbiol:is rdf:resource="http://identifiers.org/chebi/CHEBI:37328"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#entity_17">
<bqbiol:isPartOf rdf:resource="./Kapela.cellml#entity_5"/>
<bqbiol:is rdf:resource="http://identifiers.org/chebi/CHEBI:25450"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#tau_rel">
<dcterms:description>Ryanodine receptor calcium release time constant</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#phi_R">
<dcterms:description>Sodium/calcium exchanger reverse reaction rate</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#z_Ca">
<dcterms:description>Valence of calcium</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#R_10">
<bqbiol:isPropertyOf rdf:resource="./Kapela.cellml#entity_21"/>
<bqbiol:isVersionOf rdf:resource="http://bhi.washington.edu/OPB#OPB_01298"/>
<dcterms:description>Ryanodine receptor state with calcium bound to the activation site</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#sink_15">
<semsim:hasMultiplier>1.0</semsim:hasMultiplier>
<semsim:hasPhysicalEntityReference rdf:resource="./Kapela.cellml#entity_13"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#k_aG">
<dcterms:description>G protein activation rate</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#r_hG0">
<dcterms:description>Iniital inositol trisphosphate and PIP2 baseline production rate factor</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#process_1">
<semsim:hasSinkParticipant rdf:resource="./Kapela.cellml#sink_1"/>
<semsim:hasSourceParticipant rdf:resource="./Kapela.cellml#source_1"/>
<dcterms:description>Total cell voltage gated potassium channel current</dcterms:description>
<semsim:name>Voltage gated potassium channel current</semsim:name>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#K_NSC">
<dcterms:description>Nonselective cation channel DAG concentration at 50% maximal response</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#V_cGMP0">
<dcterms:description>Initial reaction velocity of cyclic GMP formation</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#Ibar_SERCA">
<dcterms:description>Total cell sarcoplasmic/endoplasmic reticulum calcium ATPase maximal current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#R_cGMP0">
<dcterms:description>Large conductance calcium activated potassium channel cyclic GMP regulatory factor</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#OPtot_IP3">
<bqbiol:isPropertyOf rdf:resource="./Kapela.cellml#entity_41"/>
<bqbiol:isVersionOf rdf:resource="http://bhi.washington.edu/OPB#OPB_01298"/>
<dcterms:description>Total open probability of the IP3 receptor including cytosolic calcium and IP3 sensitivites</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#source_14">
<semsim:hasMultiplier>1.0</semsim:hasMultiplier>
<semsim:hasPhysicalEntityReference rdf:resource="./Kapela.cellml#entity_4"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#Istim_amp">
<dcterms:description>Amplitude of injected current to stimulate response in vascular smooth muscle cell</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#Sbar_CM">
<bqbiol:isPropertyOf rdf:resource="./Kapela.cellml#entity_35"/>
<bqbiol:isVersionOf rdf:resource="http://bhi.washington.edu/OPB#OPB_00340"/>
<dcterms:description>Average cytosolic calmodulin concentration</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#K_r2">
<dcterms:description>Sarcoplasmic reticulum ryanodine receptor rate of calcium binding to inactivation site</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#source_2">
<semsim:hasMultiplier>1.0</semsim:hasMultiplier>
<semsim:hasPhysicalEntityReference rdf:resource="./Kapela.cellml#entity_4"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#entity_18">
<bqbiol:isPartOf rdf:resource="./Kapela.cellml#entity_3"/>
<bqbiol:is rdf:resource="http://identifiers.org/fma/FMA:63841"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#entity_1">
<bqbiol:isPartOf rdf:resource="./Kapela.cellml#entity_2"/>
<bqbiol:is rdf:resource="http://identifiers.org/chebi/CHEBI:29108"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#k_DsGC">
<dcterms:description>Soluble guanylate cyclase activation and cyclic GMP formation rate constant</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#K_i0">
<dcterms:description>Initial intracellular potassium concentration</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#k_m2sGC">
<dcterms:description>Soluble guanylate cyclase activation and cyclic GMP formation rate constant</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#cGMP_i">
<bqbiol:isPropertyOf rdf:resource="./Kapela.cellml#entity_24"/>
<bqbiol:isVersionOf rdf:resource="http://bhi.washington.edu/OPB#OPB_00340"/>
<dcterms:description>Intracellular cGMP concentration</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#R_010">
<dcterms:description>Initial ryanodine receptor state with calcium bound to the inactivation site</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#R_ClcGMPmin">
<dcterms:description>Calcium activated chloride channel cyclic GMP independent factor</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#I_PMCA">
<bqbiol:isPropertyOf rdf:resource="./Kapela.cellml#process_9"/>
<bqbiol:isVersionOf rdf:resource="http://bhi.washington.edu/OPB#OPB_00318"/>
<dcterms:description>Total cell plasma membrane calcium ATPase current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#k_rG">
<dcterms:description>Alpha adrenoceptor recycling rate</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#source_17">
<semsim:hasMultiplier>1.0</semsim:hasMultiplier>
<semsim:hasPhysicalEntityReference rdf:resource="./Kapela.cellml#entity_4"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#ICa_NSC">
<bqbiol:isPropertyOf rdf:resource="./Kapela.cellml#process_4"/>
<bqbiol:isVersionOf rdf:resource="http://bhi.washington.edu/OPB#OPB_00318"/>
<dcterms:description>Total cell nonselective cation channel calcium current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#source_3">
<semsim:hasMultiplier>1.0</semsim:hasMultiplier>
<semsim:hasPhysicalEntityReference rdf:resource="./Kapela.cellml#entity_11"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#entity_19">
<bqbiol:isPartOf rdf:resource="./Kapela.cellml#entity_20"/>
<semsim:name>Ryanodine receptor 2 with calcium bound to both the activation and inactivation sites</semsim:name>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#tau_q1">
<dcterms:description>Voltage gated potassium channel fast inactivaton gate time constant</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#entity_0">
<bqbiol:is rdf:resource="http://identifiers.org/chebi/CHEBI:29101"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#qbar">
<dcterms:description>Voltage gated potassium channel fast and slow activation gate steady state open probability</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#p_s">
<dcterms:description>Large conductance calcium activated potassium channel slow activation gate open probability</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#tau_sGC">
<dcterms:description>cyclic GMP rate of the reaction velocity time constant</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#P_Cl">
<dcterms:description>Calcium activated chloride channel activation gate open probability</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#INa_NSC">
<dcterms:description>Total cell nonselective cation channel maximal sodium current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#K_r1">
<dcterms:description>Sarcoplasmic reticulum ryanodine receptor rate of calcium binding to activation site</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#Na_e">
<bqbiol:isPropertyOf rdf:resource="./Kapela.cellml#entity_12"/>
<bqbiol:isVersionOf rdf:resource="http://bhi.washington.edu/OPB#OPB_00340"/>
<dcterms:description>Extracellular sodium concentration</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#k_2sGC">
<dcterms:description>Soluble guanylate cyclase activation and cyclic GMP formation rate constant</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#NE">
<bqbiol:isPropertyOf rdf:resource="./Kapela.cellml#entity_27"/>
<bqbiol:isVersionOf rdf:resource="http://bhi.washington.edu/OPB#OPB_00340"/>
<dcterms:description>Extracellular norepinephrine concentration</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#Vbar_cGMP">
<dcterms:description>Steady state velocity of cyclic GMP formation</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#K_dCM">
<dcterms:description>Calmoduling-calcium dissociation constant</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#I_NSC">
<bqbiol:isPropertyOf rdf:resource="./Kapela.cellml#process_6"/>
<bqbiol:isVersionOf rdf:resource="http://bhi.washington.edu/OPB#OPB_00318"/>
<dcterms:description>Total cell nonselective cation channel current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#source_16">
<semsim:hasMultiplier>1.0</semsim:hasMultiplier>
<semsim:hasPhysicalEntityReference rdf:resource="./Kapela.cellml#entity_1"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#tau_fL">
<dcterms:description>L-type calcium channel f_L gate time constant</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#dbar_L">
<dcterms:description>Voltage operated calcium channel d gate steady state open probability</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#IK_NaKCl">
<dcterms:description>Total cell sodium/potassium/chloride cotransporter potassium current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#A0_sGC">
<dcterms:description>cGMP production rate term</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#g_NCX">
<dcterms:description>Sodium/calcium exchanger current factor</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#source_0">
<semsim:hasMultiplier>1.0</semsim:hasMultiplier>
<semsim:hasPhysicalEntityReference rdf:resource="./Kapela.cellml#entity_1"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#K_cG">
<dcterms:description>Calcium - phospolipase C dissociation constant</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#g_Kleak">
<bqbiol:isPropertyOf rdf:resource="./Kapela.cellml#entity_39"/>
<bqbiol:isVersionOf rdf:resource="http://bhi.washington.edu/OPB#OPB_00015"/>
<dcterms:description>Potassium leak channel maximal conductance</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#R_supSG0">
<dcterms:description>Initial number of unphosporylated alpha adrenoreceptors</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#p_f">
<dcterms:description>Large conductance calcium activated potassium channel fast activation gate open probability</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#q_1">
<dcterms:description>Voltage gated potassium channel fast activation gate open probability</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#sink_18">
<semsim:hasMultiplier>1.0</semsim:hasMultiplier>
<semsim:hasPhysicalEntityReference rdf:resource="./Kapela.cellml#entity_33"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#entity_40">
<bqbiol:is rdf:resource="http://identifiers.org/chebi/CHEBI:29108"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#K_mr1">
<dcterms:description>Sarcoplasmic reticulum ryanodine receptor rate of calcium unbinding from activation site</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#fbar_L">
<dcterms:description>Steady state L-type calcium channel inactivation gate open probability</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#B5_sGC">
<dcterms:description>cGMP porduction rate NO sensitivity term</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#Bbar_F">
<dcterms:description>Concentration of other Ca buffers</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#R_NaKClcGMP">
<dcterms:description>Sodium/potassium/chloride cotransporter cyclic GMP sensitivity</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#alpha_G">
<dcterms:description>Alpha adrenoceptor G protein effective signal gain parameter</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#source_1">
<semsim:hasMultiplier>1.0</semsim:hasMultiplier>
<semsim:hasPhysicalEntityReference rdf:resource="./Kapela.cellml#entity_6"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#I_tr">
<bqbiol:isPropertyOf rdf:resource="./Kapela.cellml#process_11"/>
<bqbiol:isVersionOf rdf:resource="http://bhi.washington.edu/OPB#OPB_00318"/>
<dcterms:description>Total cell transfer from SR matrix to SR cisternae calcium current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#entity_41">
<bqbiol:isPartOf rdf:resource="./Kapela.cellml#entity_20"/>
<semsim:name>Open probability of the inositol trisphosphate receptor type 1 (human)</semsim:name>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#V_m0">
<dcterms:description>Initial vascular smooth muscle cell plasma membrane potential</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#phi_F">
<dcterms:description>Sodium/calcium exchanger forward reaction rate</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#V_cGMPmax">
<dcterms:description>Maximal reaction velocity of cyclic GMP formation</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#Vol_SRr">
<bqbiol:isPropertyOf rdf:resource="./Kapela.cellml#entity_30"/>
<bqbiol:isVersionOf rdf:resource="http://bhi.washington.edu/OPB#OPB_00154"/>
<dcterms:description>Sarcoplasmic reticulum volume associated with the ryanodine receptor release which is also called the terminal cisternae</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#Pbar_SOC">
<dcterms:description>Store operated cation channel activation gate steady state open probability</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#N_BKCa">
<dcterms:description>Large conductance calcium activated potassium channel density per unit cell surface area</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#CSQNbar">
<bqbiol:isPropertyOf rdf:resource="./Kapela.cellml#entity_43"/>
<bqbiol:isVersionOf rdf:resource="http://bhi.washington.edu/OPB#OPB_00340"/>
<dcterms:description>Average sarcoplasmic reticulum calsequestrin concentration</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#R_cGMP">
<dcterms:description>Large conductance calcium activated potassium channel cyclic GMP sensitivity factor</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#R_110">
<dcterms:description>Initial ryanodine receptor state with calcium bound to both the activation and inactivation sites</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#d_L0">
<dcterms:description>Initial L-type calcium channel activation gate probability</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#source_18">
<semsim:hasMultiplier>1.0</semsim:hasMultiplier>
<semsim:hasPhysicalEntityReference rdf:resource="./Kapela.cellml#entity_31"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#dV_50KCacGMP">
<dcterms:description>Large conductance calcium activated potassium channel maximal cGMP independent voltage shift at 50% response</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#time">
<bqbiol:is rdf:resource="http://identifiers.org/opb/OPB_01023"/>
<dcterms:description>Time</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#NE_amp">
<dcterms:description>Extracellularly dosed norepinephrine concentration</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#Ca_i">
<bqbiol:isPropertyOf rdf:resource="./Kapela.cellml#entity_4"/>
<bqbiol:isVersionOf rdf:resource="http://bhi.washington.edu/OPB#OPB_00340"/>
<dcterms:description>Intracellular calcium concentration</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#k_1sGC">
<dcterms:description>Soluble guanylate cyclase activation and cyclic GMP formation rate constant</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#K_SOC">
<dcterms:description>Store operated cation channel calcium concentration at 50% maiximal response</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#R_NO">
<dcterms:description>Large conductance calcium activated potassium channel nitric oxide sensitivity</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#source_6">
<semsim:hasMultiplier>3.0</semsim:hasMultiplier>
<semsim:hasPhysicalEntityReference rdf:resource="./Kapela.cellml#entity_11"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#env_time">
<bqbiol:is rdf:resource="http://identifiers.org/opb/OPB_01023"/>
<dcterms:description>Time</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#entity_5">
<bqbiol:isPartOf rdf:resource="./Kapela.cellml#entity_3"/>
<bqbiol:is rdf:resource="http://identifiers.org/fma/FMA:66836"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#gNa_SOC">
<bqbiol:isPropertyOf rdf:resource="./Kapela.cellml#entity_15"/>
<bqbiol:isVersionOf rdf:resource="http://bhi.washington.edu/OPB#OPB_00015"/>
<dcterms:description>Store operated cation channel maximal sodium conductance</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#K_mPMCA">
<dcterms:description>Plasma membrane calcium ATPase Michaelis constant</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#I_ClCa">
<bqbiol:isPropertyOf rdf:resource="./Kapela.cellml#process_13"/>
<bqbiol:isVersionOf rdf:resource="http://bhi.washington.edu/OPB#OPB_00318"/>
<dcterms:description>Total cell calcium activated chloride channel current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#entity_42">
<bqbiol:isPartOf rdf:resource="./Kapela.cellml#entity_37"/>
<bqbiol:is rdf:resource="http://identifiers.org/chebi/CHEBI:18035"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#I_Kleak">
<bqbiol:isVersionOf rdf:resource="http://bhi.washington.edu/OPB#OPB_00318"/>
<dcterms:description>Total cell potassium leak channel current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#entity_30">
<bqbiol:isPartOf rdf:resource="./Kapela.cellml#entity_20"/>
<bqbiol:is rdf:resource="http://identifiers.org/fma/FMA:67120"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#ICl_NaKCl">
<dcterms:description>Total cell sodium/potassium/chloride cotransporter chloride current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#f_L">
<dcterms:description>L-type calcium channel inactivation gate open probability</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#E_Ca">
<bqbiol:isPropertyOf rdf:resource="./Kapela.cellml#entity_40"/>
<bqbiol:isVersionOf rdf:resource="http://bhi.washington.edu/OPB#OPB_01581"/>
<dcterms:description>Nernst potential for calcium</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#q_20">
<dcterms:description>Initial voltage gated potassium channel slow activation gate open probability</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#K_ClcGMP">
<dcterms:description>Calcium activated chloride channel cyclic GMP activation effective concentration at 50% maximal response</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#k_m1sGC">
<dcterms:description>Soluble guanylate cyclase activation and cyclic GMP formation rate constant</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#Cl_i">
<bqbiol:isPropertyOf rdf:resource="./Kapela.cellml#entity_31"/>
<bqbiol:isVersionOf rdf:resource="http://bhi.washington.edu/OPB#OPB_00340"/>
<dcterms:description>Intracellular chloride concentration</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#process_6">
<semsim:hasSinkParticipant rdf:resource="./Kapela.cellml#sink_10"/>
<semsim:hasSinkParticipant rdf:resource="./Kapela.cellml#sink_9"/>
<semsim:hasSinkParticipant rdf:resource="./Kapela.cellml#sink_8"/>
<semsim:hasSourceParticipant rdf:resource="./Kapela.cellml#source_10"/>
<semsim:hasSourceParticipant rdf:resource="./Kapela.cellml#source_9"/>
<semsim:hasSourceParticipant rdf:resource="./Kapela.cellml#source_8"/>
<dcterms:description>Total cell plasma membrane calcium ATPase current</dcterms:description>
<semsim:name>Total nonselective cation channel current</semsim:name>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#sink_6">
<semsim:hasMultiplier>2.0</semsim:hasMultiplier>
<semsim:hasPhysicalEntityReference rdf:resource="./Kapela.cellml#entity_7"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#F">
<bqbiol:is rdf:resource="http://identifiers.org/opb/OPB_00089"/>
<dcterms:description>Faraday constant</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#V_m">
<bqbiol:isPropertyOf rdf:resource="./Kapela.cellml#entity_18"/>
<bqbiol:isVersionOf rdf:resource="http://bhi.washington.edu/OPB#OPB_00506"/>
<dcterms:description>Vascular smooth muscle cell plasma membrane potential</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#K_IP3">
<dcterms:description>IP3 receptor IP3 dissociation constant</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#Vol_Ca">
<bqbiol:isPropertyOf rdf:resource="./Kapela.cellml#entity_14"/>
<bqbiol:isVersionOf rdf:resource="http://bhi.washington.edu/OPB#OPB_00154"/>
<dcterms:description>Cytosolic volume available to calcium</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#source_7">
<semsim:hasMultiplier>2.0</semsim:hasMultiplier>
<semsim:hasPhysicalEntityReference rdf:resource="./Kapela.cellml#entity_6"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#entity_4">
<bqbiol:isPartOf rdf:resource="./Kapela.cellml#entity_5"/>
<bqbiol:is rdf:resource="http://identifiers.org/chebi/CHEBI:29108"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#entity_43">
<bqbiol:isPartOf rdf:resource="./Kapela.cellml#entity_9"/>
<bqbiol:is rdf:resource="http://purl.obolibrary.org/obo/PR_000005057"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#entity_31">
<bqbiol:isPartOf rdf:resource="./Kapela.cellml#entity_5"/>
<bqbiol:is rdf:resource="http://identifiers.org/chebi/CHEBI:30120"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#Na_i">
<bqbiol:isPropertyOf rdf:resource="./Kapela.cellml#entity_11"/>
<bqbiol:isVersionOf rdf:resource="http://bhi.washington.edu/OPB#OPB_00340"/>
<dcterms:description>Intracellular sodium concentration</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#IP3">
<bqbiol:isPropertyOf rdf:resource="./Kapela.cellml#entity_17"/>
<bqbiol:isVersionOf rdf:resource="http://bhi.washington.edu/OPB#OPB_00340"/>
<dcterms:description>Intracellular inositol trisphosphate concentration</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#k_dG">
<dcterms:description>G protein deactivation rate</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#z_Cl">
<dcterms:description>Valence of chloride</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#N_Avo">
<bqbiol:is rdf:resource="http://identifiers.org/opb/OPB_01622"/>
<dcterms:description>Avogadros number</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#I_NCX">
<bqbiol:isPropertyOf rdf:resource="./Kapela.cellml#process_10"/>
<bqbiol:isVersionOf rdf:resource="http://bhi.washington.edu/OPB#OPB_00318"/>
<dcterms:description>Total cell sodium/calcium exchanger current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#process_7">
<semsim:hasSinkParticipant rdf:resource="./Kapela.cellml#sink_11"/>
<semsim:hasSourceParticipant rdf:resource="./Kapela.cellml#source_11"/>
<dcterms:description>Caclium current through the inositol trisphosphate receptor on the sarcoplasmic reticulum</dcterms:description>
<semsim:name>Large conductance calcium activated potassium channel current</semsim:name>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#K_2G">
<dcterms:description>Alpha adrenoceptor phosporylated dissociation constant</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#IK_totm">
<dcterms:description>Total cell plasma membrane potassium current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#tau_dL">
<dcterms:description>L-type calcium channel d_L gate time constant</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#K_ClCacGMP">
<dcterms:description>Calcium activated chloride channel cyclic GMP sensitivity parameter</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#sink_5">
<semsim:hasMultiplier>1.0</semsim:hasMultiplier>
<semsim:hasPhysicalEntityReference rdf:resource="./Kapela.cellml#entity_13"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#R_supSPG">
<dcterms:description>Number of phosporylated alpha adrenoreceptors</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#z_Na">
<dcterms:description>Valence of sodium</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#entity_3">
<bqbiol:is rdf:resource="http://identifiers.org/fma/FMA:284560"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#A_m">
<bqbiol:isPropertyOf rdf:resource="./Kapela.cellml#entity_18"/>
<bqbiol:isVersionOf rdf:resource="http://bhi.washington.edu/OPB#OPB_01043"/>
<dcterms:description>Surface area of the smooth muscle cell</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#INa_SOC">
<dcterms:description>Total cell store operated cation channel maximal sodium current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#R_supSG">
<dcterms:description>Number of unphosporylated alpha adrenoreceptors</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#tau_q2">
<dcterms:description>Voltage gated potassium channel slow inactivaton gate time constant</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#R_NO0">
<dcterms:description>Initial large conductance calcium activated potassium channel nitric oxide sensitivity</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#sink_9">
<semsim:hasMultiplier>1.0</semsim:hasMultiplier>
<semsim:hasPhysicalEntityReference rdf:resource="./Kapela.cellml#entity_12"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#source_4">
<semsim:hasMultiplier>1.0</semsim:hasMultiplier>
<semsim:hasPhysicalEntityReference rdf:resource="./Kapela.cellml#entity_1"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#I_IP3">
<bqbiol:isPropertyOf rdf:resource="./Kapela.cellml#process_3"/>
<bqbiol:isVersionOf rdf:resource="http://bhi.washington.edu/OPB#OPB_00318"/>
<dcterms:description>Total cell IP3 receptor calcium current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#FRT">
<dcterms:description>F over RT coefficient</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#entity_44">
<bqbiol:is rdf:resource="http://identifiers.org/chebi/CHEBI:29103"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#entity_32">
<bqbiol:isPartOf rdf:resource="./Kapela.cellml#entity_16"/>
<bqbiol:is rdf:resource="http://identifiers.org/go/GO:0008076"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#entity_20">
<bqbiol:isPartOf rdf:resource="./Kapela.cellml#entity_3"/>
<bqbiol:is rdf:resource="http://identifiers.org/fma/FMA:67225"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#P_VOCC">
<dcterms:description>L-type calcium channel maximal calcium permeability</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#RT">
<dcterms:description>Product of ideal gas number and temperature</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#K_CSQN">
<dcterms:description>Binding affinity of calsequestrin in sarcoplasmic reticulum</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#Vol_SRu">
<bqbiol:isPropertyOf rdf:resource="./Kapela.cellml#entity_28"/>
<bqbiol:isVersionOf rdf:resource="http://bhi.washington.edu/OPB#OPB_00154"/>
<dcterms:description>Sarcoplasmic reticulum volume associated with the SERCA uptake</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#gamma_G">
<dcterms:description>PIP2 particle number to concentration conversion term</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#p_f0">
<dcterms:description>Initial large conductance calcium activated potassium channel fast activation gate open probability</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#gamma_NCX">
<dcterms:description>Sodium/calcium exchanger parameter</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#L_NaKCl">
<dcterms:description>Sodium/potassium/chloride contransporter scaled permeability parameter</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#process_8">
<semsim:hasSinkParticipant rdf:resource="./Kapela.cellml#sink_12"/>
<semsim:hasSourceParticipant rdf:resource="./Kapela.cellml#source_12"/>
<dcterms:description>Total cell ryanodine receptor calcium current</dcterms:description>
<semsim:name>Ryanodine receptor calcium current</semsim:name>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#Ca_u0">
<dcterms:description>Initial sarcoplasmic reticulum uptake space calcium concentration</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#I_SOC">
<bqbiol:isPropertyOf rdf:resource="./Kapela.cellml#process_2"/>
<bqbiol:isVersionOf rdf:resource="http://bhi.washington.edu/OPB#OPB_00318"/>
<dcterms:description>Total cell store operated cation channel current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#process_12">
<semsim:hasSinkParticipant rdf:resource="./Kapela.cellml#sink_17"/>
<semsim:hasSourceParticipant rdf:resource="./Kapela.cellml#source_17"/>
<dcterms:description>Total cell L-type calcium channel current</dcterms:description>
<semsim:name>L-type calcium channel current</semsim:name>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#G_TG">
<dcterms:description>Total number of G proteins</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#R_leak">
<dcterms:description>Ryanodine receptor calcium leak factor</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#entity_2">
<bqbiol:isPartOf rdf:resource="./Kapela.cellml#entity_3"/>
<bqbiol:is rdf:resource="http://identifiers.org/fma/FMA:72448"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#I_SERCA">
<bqbiol:isPropertyOf rdf:resource="./Kapela.cellml#process_0"/>
<bqbiol:isVersionOf rdf:resource="http://bhi.washington.edu/OPB#OPB_00318"/>
<dcterms:description>Total cell sarcoplasmic/endoplamic reticulum calcium APTase current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#tau_ps">
<dcterms:description>Large conductance calcium activated potassium channel slow activaton gate time constant</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#tau_SOC">
<dcterms:description>Store operated cation channel activaton gate time constant</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#source_5">
<semsim:hasMultiplier>1.0</semsim:hasMultiplier>
<semsim:hasPhysicalEntityReference rdf:resource="./Kapela.cellml#entity_4"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#sink_8">
<semsim:hasMultiplier>1.0</semsim:hasMultiplier>
<semsim:hasPhysicalEntityReference rdf:resource="./Kapela.cellml#entity_7"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#DAG">
<bqbiol:isPropertyOf rdf:resource="./Kapela.cellml#entity_42"/>
<bqbiol:isVersionOf rdf:resource="http://bhi.washington.edu/OPB#OPB_00340"/>
<dcterms:description>Diacylglycerol concentration</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#g_Kv">
<bqbiol:isPropertyOf rdf:resource="./Kapela.cellml#entity_32"/>
<bqbiol:isVersionOf rdf:resource="http://bhi.washington.edu/OPB#OPB_00015"/>
<dcterms:description>Voltage gated potassium channel maximal conductance</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#entity_33">
<bqbiol:isPartOf rdf:resource="./Kapela.cellml#entity_8"/>
<bqbiol:is rdf:resource="http://identifiers.org/chebi/CHEBI:30120"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#IK_NSC">
<dcterms:description>Total cell nonselective cation channel maximal potassium current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#entity_21">
<bqbiol:isPartOf rdf:resource="./Kapela.cellml#entity_20"/>
<semsim:name>Ryanodine receptor 2 with calcium bound to the activation site</semsim:name>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#A1_sGC">
<dcterms:description>cGMP production rate term</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#k_eG">
<dcterms:description>Alpha adrenoceptor endocytosis rate</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#P_KCa">
<dcterms:description>Large conductance calcium activated potassium channel total open probability</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#process_9">
<semsim:hasSinkParticipant rdf:resource="./Kapela.cellml#sink_13"/>
<semsim:hasSourceParticipant rdf:resource="./Kapela.cellml#source_13"/>
<dcterms:description>Total cell plasma membrane calcium ATPase current</dcterms:description>
<semsim:name>Plasma membrane calcium ATPase current</semsim:name>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#K_1G">
<dcterms:description>Alpha adrenoceptor unphosporylated dissociation constant</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#G">
<bqbiol:isPropertyOf rdf:resource="./Kapela.cellml#entity_36"/>
<bqbiol:isVersionOf rdf:resource="http://bhi.washington.edu/OPB#OPB_01001"/>
<dcterms:description>Number of active G proteins</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#sink_7">
<semsim:hasMultiplier>3.0</semsim:hasMultiplier>
<semsim:hasPhysicalEntityReference rdf:resource="./Kapela.cellml#entity_12"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#process_13">
<semsim:hasSinkParticipant rdf:resource="./Kapela.cellml#sink_18"/>
<semsim:hasSourceParticipant rdf:resource="./Kapela.cellml#source_18"/>
<dcterms:description>Calicum activated chloride channel current</dcterms:description>
<semsim:name>Calcium activated chloride channel current</semsim:name>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#PK_NSC">
<dcterms:description>Nonselective cation channel whole cell potasium permeability</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#gCa_SOC">
<bqbiol:isPropertyOf rdf:resource="./Kapela.cellml#entity_15"/>
<bqbiol:isVersionOf rdf:resource="http://bhi.washington.edu/OPB#OPB_00015"/>
<dcterms:description>Store operated cation channel maximal calcium conductance</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#Ca_e">
<bqbiol:isPropertyOf rdf:resource="./Kapela.cellml#entity_13"/>
<bqbiol:isVersionOf rdf:resource="http://bhi.washington.edu/OPB#OPB_00340"/>
<dcterms:description>Extracellular Ca concentration</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#d_NCX">
<dcterms:description>Sodium-calcium exchanger sensitivity factor</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#K_i">
<bqbiol:isPropertyOf rdf:resource="./Kapela.cellml#entity_6"/>
<bqbiol:isVersionOf rdf:resource="http://bhi.washington.edu/OPB#OPB_00340"/>
<dcterms:description>Intracellular potassium concentration</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#sink_12">
<semsim:hasMultiplier>1.0</semsim:hasMultiplier>
<semsim:hasPhysicalEntityReference rdf:resource="./Kapela.cellml#entity_4"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#R_11">
<bqbiol:isPropertyOf rdf:resource="./Kapela.cellml#entity_19"/>
<bqbiol:isVersionOf rdf:resource="http://bhi.washington.edu/OPB#OPB_01298"/>
<dcterms:description>Ryanodine receptor state with calcium bound to both the activation and inactivation sites</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#entity_34">
<bqbiol:isPartOf rdf:resource="./Kapela.cellml#entity_16"/>
<semsim:name>Calcium activated chloride channel</semsim:name>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#process_2">
<semsim:hasSinkParticipant rdf:resource="./Kapela.cellml#sink_3"/>
<semsim:hasSinkParticipant rdf:resource="./Kapela.cellml#sink_2"/>
<semsim:hasSourceParticipant rdf:resource="./Kapela.cellml#source_3"/>
<semsim:hasSourceParticipant rdf:resource="./Kapela.cellml#source_2"/>
<dcterms:description>Calicum activated chloride channel current</dcterms:description>
<semsim:name>Store operated cation channel current</semsim:name>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#entity_22">
<bqbiol:isPartOf rdf:resource="./Kapela.cellml#entity_20"/>
<semsim:name>Ryanodine receptor 2 with calcium bound to inactivation site</semsim:name>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#entity_10">
<bqbiol:isPartOf rdf:resource="./Kapela.cellml#entity_3"/>
<bqbiol:is rdf:resource="http://identifiers.org/fma/FMA:67120"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#NO_base">
<dcterms:description>Baseline cytosolic nitric oxide concentration</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#p_K">
<dcterms:description>Voltage gated potassium channel activation gate open probability</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#I_Kv">
<bqbiol:isPropertyOf rdf:resource="./Kapela.cellml#process_1"/>
<bqbiol:isVersionOf rdf:resource="http://bhi.washington.edu/OPB#OPB_00318"/>
<dcterms:description>Total cell voltage gated potassium channel current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#Cl_e">
<bqbiol:isPropertyOf rdf:resource="./Kapela.cellml#entity_33"/>
<bqbiol:isVersionOf rdf:resource="http://bhi.washington.edu/OPB#OPB_00340"/>
<dcterms:description>Extracellular chloride concentration</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#PCa_NSC">
<dcterms:description>Nonselective cation channel whole cell calcium permeability</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#P_SOC">
<dcterms:description>Store operated cation channel activation gate open probability</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#R">
<bqbiol:is rdf:resource="http://identifiers.org/opb/OPB_00410"/>
<dcterms:description>Ideal gas constant</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#entity_9">
<bqbiol:isPartOf rdf:resource="./Kapela.cellml#entity_3"/>
<bqbiol:is rdf:resource="http://identifiers.org/fma/FMA:72448"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#process_10">
<semsim:hasSinkParticipant rdf:resource="./Kapela.cellml#sink_15"/>
<semsim:hasSinkParticipant rdf:resource="./Kapela.cellml#sink_14"/>
<semsim:hasSourceParticipant rdf:resource="./Kapela.cellml#source_15"/>
<semsim:hasSourceParticipant rdf:resource="./Kapela.cellml#source_14"/>
<dcterms:description>Total cell sodium/calcium exchanger current</dcterms:description>
<semsim:name>Sodium/calcium exchanger current</semsim:name>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#sink_2">
<semsim:hasMultiplier>1.0</semsim:hasMultiplier>
<semsim:hasPhysicalEntityReference rdf:resource="./Kapela.cellml#entity_12"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#p_s0">
<dcterms:description>Initial large conductance calcium activated potassium channel slow activation gate open probability</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#k_onIP3">
<dcterms:description>IP3 receptor rate of calcium binding to inhibition site</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#Na_i0">
<dcterms:description>Initial intracellular sodium concentration</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#K_dKe">
<dcterms:description>Sodium/potassium ATPase extracellular potassium binding rate</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#R_00">
<bqbiol:isPropertyOf rdf:resource="./Kapela.cellml#entity_23"/>
<bqbiol:isVersionOf rdf:resource="http://bhi.washington.edu/OPB#OPB_01298"/>
<dcterms:description>Ryanodine receptor state with no active site or inactive site calcium bond</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#entity_35">
<bqbiol:isPartOf rdf:resource="./Kapela.cellml#entity_5"/>
<bqbiol:is rdf:resource="http://purl.obolibrary.org/obo/PR_P62158"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#process_3">
<semsim:hasSinkParticipant rdf:resource="./Kapela.cellml#sink_4"/>
<semsim:hasSourceParticipant rdf:resource="./Kapela.cellml#source_4"/>
<dcterms:description>Total cell transfer from SR matrix to SR cisternae calcium current</dcterms:description>
<semsim:name>IP3 receptor calcium current</semsim:name>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#entity_23">
<bqbiol:isPartOf rdf:resource="./Kapela.cellml#entity_20"/>
<semsim:name>Ryanodine receptor 2 with no calcium bound</semsim:name>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#sink_13">
<semsim:hasMultiplier>1.0</semsim:hasMultiplier>
<semsim:hasPhysicalEntityReference rdf:resource="./Kapela.cellml#entity_13"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#I_BKCa">
<bqbiol:isPropertyOf rdf:resource="./Kapela.cellml#process_7"/>
<bqbiol:isVersionOf rdf:resource="http://bhi.washington.edu/OPB#OPB_00318"/>
<dcterms:description>Total cell large conductance calcium activated potassium channel current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#entity_11">
<bqbiol:isPartOf rdf:resource="./Kapela.cellml#entity_5"/>
<bqbiol:is rdf:resource="http://identifiers.org/chebi/CHEBI:29101"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#E_Cl">
<bqbiol:isPropertyOf rdf:resource="./Kapela.cellml#entity_38"/>
<bqbiol:isVersionOf rdf:resource="http://bhi.washington.edu/OPB#OPB_01581"/>
<dcterms:description>Nernst potential for chloride</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#K_mpde">
<dcterms:description>Soluble guanylate cyclase activation and cyclic GMP formation parameter</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#R_TG">
<dcterms:description>Total number of alpha adrenoreceptors</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#Q">
<dcterms:description>Sodium/calcium exchanger temperature correction factor</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#r_rG">
<dcterms:description>PIP2 baseline production rate</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#Na_dNai">
<dcterms:description>Sodium/potassium ATPase intracellular sodium binding rate</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#K_actIP3">
<dcterms:description>IP3 receptor calcium activation dissociation constant</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#entity_8">
<bqbiol:is rdf:resource="http://identifiers.org/fma/FMA:9672"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#process_11">
<semsim:hasSinkParticipant rdf:resource="./Kapela.cellml#sink_16"/>
<semsim:hasSourceParticipant rdf:resource="./Kapela.cellml#source_16"/>
<dcterms:description>Total cell transfer from SR matrix to SR cisternae calcium current</dcterms:description>
<semsim:name>Internal SR calcium current</semsim:name>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#h_IP30">
<dcterms:description>Initial IP3 receptor activation gate open probability</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#sink_1">
<semsim:hasMultiplier>1.0</semsim:hasMultiplier>
<semsim:hasPhysicalEntityReference rdf:resource="./Kapela.cellml#entity_7"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#source_11">
<semsim:hasMultiplier>1.0</semsim:hasMultiplier>
<semsim:hasPhysicalEntityReference rdf:resource="./Kapela.cellml#entity_6"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#R_01">
<bqbiol:isPropertyOf rdf:resource="./Kapela.cellml#entity_22"/>
<bqbiol:isVersionOf rdf:resource="http://bhi.washington.edu/OPB#OPB_01298"/>
<dcterms:description>Ryanodine receptor state with calcium bound to the inactivation site</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#sink_10">
<semsim:hasMultiplier>1.0</semsim:hasMultiplier>
<semsim:hasPhysicalEntityReference rdf:resource="./Kapela.cellml#entity_13"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#entity_7">
<bqbiol:isPartOf rdf:resource="./Kapela.cellml#entity_8"/>
<bqbiol:is rdf:resource="http://identifiers.org/chebi/CHEBI:29103"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#Ibar_IP3">
<dcterms:description>Total cell IP3 receptor maximal rate of calcium release</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#entity_36">
<bqbiol:isPartOf rdf:resource="./Kapela.cellml#entity_16"/>
<bqbiol:is rdf:resource="http://identifiers.org/chebi/CHEBI:16235"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#entity_24">
<bqbiol:isPartOf rdf:resource="./Kapela.cellml#entity_5"/>
<bqbiol:is rdf:resource="http://identifiers.org/chebi/CHEBI:16356"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#entity_12">
<bqbiol:isPartOf rdf:resource="./Kapela.cellml#entity_8"/>
<bqbiol:is rdf:resource="http://identifiers.org/chebi/CHEBI:29101"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#cGMP_i0">
<dcterms:description>Initial intracellular cGMP concentration</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#tau_pf">
<dcterms:description>Large conductance calcium activated potassium channel fast activaton gate time constant</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#process_4">
<semsim:hasSinkParticipant rdf:resource="./Kapela.cellml#sink_5"/>
<semsim:hasSourceParticipant rdf:resource="./Kapela.cellml#source_5"/>
<dcterms:description>Total cell nonselective cation channel calcium current</dcterms:description>
<semsim:name>Nonselective cation channel calcium current</semsim:name>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#source_8">
<semsim:hasMultiplier>1.0</semsim:hasMultiplier>
<semsim:hasPhysicalEntityReference rdf:resource="./Kapela.cellml#entity_11"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#k_DrsGC">
<dcterms:description>Soluble guanylate cyclase activation and cyclic GMP formation parameter</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#k_degG">
<dcterms:description>IP3 degradation rate</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#d_NSCmin">
<dcterms:description>Minimal NSC channel activation</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#q_10">
<dcterms:description>Initial voltage gated potassium channel fast activation gate open probability</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#K_mup">
<dcterms:description>Sarcoplasmic/endoplasmic reticulum calcium ATPase Michaelis constant</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#T">
<bqbiol:isPropertyOf rdf:resource="./Kapela.cellml#entity_3"/>
<bqbiol:isVersionOf rdf:resource="http://bhi.washington.edu/OPB#OPB_00293"/>
<dcterms:description>Temperature</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#k_pdecGMP">
<dcterms:description>Soluble guanylate cyclase activation and cyclic GMP formation rate constant</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#V_50KCa0">
<dcterms:description>Initial large conductance calcium activated potassium channel voltage at 50% maximal response</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#PIP2_T">
<dcterms:description>Total number of phosphatidylinositol 4,5-bisphosphate molecules</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#n_ClcGMP">
<dcterms:description>Calcium activated chloride channel cyclic GMP sensitivity Hill coefficient</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#sink_4">
<semsim:hasMultiplier>1.0</semsim:hasMultiplier>
<semsim:hasPhysicalEntityReference rdf:resource="./Kapela.cellml#entity_4"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#E_Na">
<bqbiol:isPropertyOf rdf:resource="./Kapela.cellml#entity_0"/>
<bqbiol:isVersionOf rdf:resource="http://bhi.washington.edu/OPB#OPB_01581"/>
<dcterms:description>Nernst potential for sodium</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#f_L0">
<dcterms:description>Initial L-type calcium channel inactivation gate open probability</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#h_IP3">
<dcterms:description>IP3 receptor activation gate open probability</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#R_NCXcGMP">
<dcterms:description>Sodium/calcium exchanger cyclic GMP sensitivity</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#E_K">
<bqbiol:isPropertyOf rdf:resource="./Kapela.cellml#entity_44"/>
<bqbiol:isVersionOf rdf:resource="http://bhi.washington.edu/OPB#OPB_01581"/>
<dcterms:description>Nernst potential for potassium</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#IP3_0">
<dcterms:description>Initial intracellular inositol trisphosphate concentration</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#NO_0">
<dcterms:description>Initial intracellular nitric oxide concentration</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#entity_37">
<bqbiol:isPartOf rdf:resource="./Kapela.cellml#entity_3"/>
<bqbiol:is rdf:resource="http://identifiers.org/fma/FMA:66836"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#entity_6">
<bqbiol:isPartOf rdf:resource="./Kapela.cellml#entity_5"/>
<bqbiol:is rdf:resource="http://identifiers.org/chebi/CHEBI:29103"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#entity_25">
<bqbiol:isPartOf rdf:resource="./Kapela.cellml#entity_5"/>
<bqbiol:is rdf:resource="http://identifiers.org/chebi/CHEBI:16480"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#entity_13">
<bqbiol:isPartOf rdf:resource="./Kapela.cellml#entity_8"/>
<bqbiol:is rdf:resource="http://identifiers.org/chebi/CHEBI:29108"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#sink_11">
<semsim:hasMultiplier>1.0</semsim:hasMultiplier>
<semsim:hasPhysicalEntityReference rdf:resource="./Kapela.cellml#entity_7"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#source_10">
<semsim:hasMultiplier>1.0</semsim:hasMultiplier>
<semsim:hasPhysicalEntityReference rdf:resource="./Kapela.cellml#entity_6"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#xi_G">
<dcterms:description>Alpha adrnoceptor Fraction that are mobile</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#source_9">
<semsim:hasMultiplier>1.0</semsim:hasMultiplier>
<semsim:hasPhysicalEntityReference rdf:resource="./Kapela.cellml#entity_4"/>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#process_5">
<semsim:hasSinkParticipant rdf:resource="./Kapela.cellml#sink_7"/>
<semsim:hasSinkParticipant rdf:resource="./Kapela.cellml#sink_6"/>
<semsim:hasSourceParticipant rdf:resource="./Kapela.cellml#source_7"/>
<semsim:hasSourceParticipant rdf:resource="./Kapela.cellml#source_6"/>
<dcterms:description>Total cell sarcoplasmic/endoplamic reticulum calcium APTase current</dcterms:description>
<semsim:name>Sodium/potassium ATPase current</semsim:name>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#NO">
<bqbiol:isPropertyOf rdf:resource="./Kapela.cellml#entity_25"/>
<bqbiol:isVersionOf rdf:resource="http://bhi.washington.edu/OPB#OPB_00340"/>
<dcterms:description>Intracellular nitric oxide concentration</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#PNa_NSC">
<dcterms:description>Nonselective cation channel whole cell sodium permeability</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#n_HNai">
<dcterms:description>Sodium/potassium ATPase intracellular sodium Hill coefficient</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#Ca_u">
<bqbiol:isPropertyOf rdf:resource="./Kapela.cellml#entity_9"/>
<bqbiol:isVersionOf rdf:resource="http://bhi.washington.edu/OPB#OPB_00340"/>
<dcterms:description>Sarcoplasmic reticulum uptake space calcium concentration</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#V_50KCa">
<dcterms:description>Large conductance calcium activated potassium channel voltage at 50% maximal response</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#INa_totm">
<dcterms:description>Total cell plasma membrane sodium current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#Q_10">
<dcterms:description>Sodium/calcium exchanger temperature correction multiplier</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#ICa_SOC">
<dcterms:description>Total cell store operated cation channel maximal calcium current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#p_K0">
<dcterms:description>Initial voltage gated potassium channel activation gate open probability</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#I_stim">
<dcterms:description>Input applied stimulation current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./Kapela.cellml#sink_3">
<semsim:hasMultiplier>1.0</semsim:hasMultiplier>
<semsim:hasPhysicalEntityReference rdf:resource="./Kapela.cellml#entity_13"/>
</rdf:Description>
</rdf:RDF>
