- Author:
- AnandR <a.rampadarath@auckland.ac.nz>
- Date:
- 2019-04-05 14:25:01+13:00
- Desc:
- Added some semgen annotated models (AnandR)
- Permanent Source URI:
- https://models.cellml.org/workspace/584/rawfile/ade7933153a72bb89e0b02d75db92d6e4be285f5/Heldt_Shim_2002.cellml
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<article>
<articleinfo>
<title>Computational modeling of cardiovascular response to orthostatic stress</title>
<author>
<firstname>Catherine</firstname>
<surname>Lloyd</surname>
<affiliation>
<shortaffil>Bioengineering Institute, University of Auckland</shortaffil>
</affiliation>
</author>
</articleinfo>
<section id="sec_status">
<title>Model Status</title>
<para>
This CellML model runs in both COR and PCEnv to reproduce the published results. The units have been checked and they balance. This is a lumped parameter model for cardiac activation based on the work of Heldt et al. 2002. This CellMl model represents the whole heart (all four chambers) connected to a lumped parameter model of the circulatory system including systemic circulation, a coronary circulation, and a pulmonary circulation. The model and results are exactly the same as the
<ulink url="http://physiome.org/model/doku.php?id=Integrative_Physiology:Lumped_parameter_circulation:model_detail#Detailed_Description">JSim model</ulink>
of the same name.
</para>
</section>
<sect1 id="sec_structure">
<title>Model Structure</title>
<para>ABSTRACT: The objective of this study is to develop a model of the cardiovascular system capable of simulating the short-term (less than or equal to 5 min) transient and steady-state hemodynamic responses to head-up tilt and lower body negative pressure. The model consists of a closed-loop lumped-parameter representation of the circulation connected to set-point models of the arterial and cardiopulmonary baroreflexes. Model parameters are largely based on literature values. Model verification was performed by comparing the simulation output under baseline conditions and at different levels of orthostatic stress to sets of population-averaged hemodynamic data reported in the literature. On the basis of experimental evidence, we adjusted some model parameters to simulate experimental data. Orthostatic stress simulations are not statistically different from experimental data (two-sided test of significance with Bonferroni adjustment for multiple comparisons). Transient response characteristics of heart rate to tilt also compare well with reported data. A case study is presented on how the model is intended to be used in the future to investigate the effects of post-spaceflight orthostatic intolerance.</para>
<informalfigure float="0" id="fig_reaction_diagram">
<mediaobject>
<imageobject>
<objectinfo>
<title>model diagram</title>
</objectinfo>
<imagedata fileref="heldt_2002b.png" />
</imageobject>
</mediaobject>
<caption>Schematic diagram of the Heldt et al. 2002 circulation model.</caption>
</informalfigure>
<para>The original paper reference is cited below:</para>
<para>
Computational modeling of cardiovascular response to orthostatic stress, T. Heldt, E.B. Shim, R.D. Kamm, and R.G. Mark, 2002,
<emphasis>Journal of Applied Physiology</emphasis>
, 92, 1239-1254.
<ulink url="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=11842064&query_hl=1&itool=pubmed_docsum">PubMed ID: 11842064</ulink>
</para>
</sect1>
</article>
</documentation>
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<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1.5</cn>
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<ci>Tsv</ci>
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<plus />
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<plus />
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<ci>ylv</ci>
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<ci>Rcorao</ci>
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<eq />
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<apply>
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<eq />
<ci>Fcorea</ci>
<apply>
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<minus />
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<ci>Rcorea</ci>
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<eq />
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<minus />
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<eq />
<ci>Fcorla</ci>
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<minus />
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<ci>Pcorsac</ci>
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<eq />
<ci>Fcorlv</ci>
<apply>
<divide />
<apply>
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<ci>Pcorevc</ci>
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<eq />
<ci>Fcorsa</ci>
<apply>
<divide />
<apply>
<minus />
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<ci>Pcorcapc</ci>
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<ci>Rcorsa</ci>
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<eq />
<ci>Fcorsv</ci>
<apply>
<divide />
<apply>
<minus />
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<ci>Pcorlvc</ci>
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<ci>Rcorsv</ci>
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<eq />
<ci>Fcrb</ci>
<apply>
<divide />
<apply>
<minus />
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<eq />
<ci>Fla</ci>
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<piece>
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<ci>Rpa</ci>
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<ci>t</ci>
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<apply>
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<ci>Fpad</ci>
<ci>Rpad</ci>
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<ci>Lpad</ci>
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<ci>t</ci>
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<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">0.059999999999999984</cn>
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<apply>
<minus />
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<apply>
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<eq />
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<apply>
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<eq />
<apply>
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<ci>t</ci>
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<ci>P_QRSwave</ci>
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<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="mV">5</cn>
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<piece>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="mV">10</cn>
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<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="s">0.02</cn>
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<plus />
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<ci>Rtaod</ci>
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<ci>Rtaod</ci>
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<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">0.059999999999999984</cn>
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<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">0.060000000000000005</cn>
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<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">0.059999999999999984</cn>
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<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">0.059999999999999984</cn>
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<apply>
<minus />
<apply>
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<ci>t</ci>
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<ci>Vaop</ci>
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<ci>Faop</ci>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">16.66666666666667</cn>
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<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
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<apply>
<times />
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<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="mL">1</cn>
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<exp />
<apply>
<divide />
<ci>Vcorao</ci>
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<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
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<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">2</cn>
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<apply>
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<ci>Pcorcap</ci>
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<apply>
<divide />
<ci>Vcorcap</ci>
<ci>Ccorcap</ci>
</apply>
<apply>
<divide />
<apply>
<times />
<ci>Px1</ci>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
</apply>
<apply>
<minus />
<apply>
<exp />
<apply>
<divide />
<ci>Vcorcap</ci>
<ci>Vx1</ci>
</apply>
</apply>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq />
<ci>Pcorcapc</ci>
<apply>
<plus />
<ci>Pcorcap</ci>
<ci>Pcorisfc</ci>
</apply>
</apply>
<apply>
<eq />
<ci>Pcorea</ci>
<apply>
<minus />
<apply>
<divide />
<ci>Vcorea</ci>
<ci>Ccorea</ci>
</apply>
<apply>
<divide />
<apply>
<times />
<ci>Px1</ci>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
</apply>
<apply>
<minus />
<apply>
<exp />
<apply>
<divide />
<ci>Vcorea</ci>
<ci>Vx1</ci>
</apply>
</apply>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq />
<ci>Pcoreac</ci>
<apply>
<plus />
<ci>Pcorea</ci>
<ci>Ppcdc</ci>
</apply>
</apply>
<apply>
<eq />
<ci>Pcorev</ci>
<apply>
<minus />
<apply>
<divide />
<ci>Vcorev</ci>
<ci>Ccorev</ci>
</apply>
<apply>
<divide />
<apply>
<times />
<ci>Px2</ci>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
</apply>
<apply>
<minus />
<apply>
<exp />
<apply>
<divide />
<ci>Vcorev</ci>
<ci>Vx8</ci>
</apply>
</apply>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq />
<ci>Pcorevc</ci>
<apply>
<plus />
<ci>Pcorev</ci>
<ci>Ppcdc</ci>
</apply>
</apply>
<apply>
<eq />
<ci>Pcorisfc</ci>
<apply>
<abs />
<apply>
<divide />
<apply>
<minus />
<ci>Plvc</ci>
<ci>Ppcdc</ci>
</apply>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">2</cn>
</apply>
</apply>
</apply>
<apply>
<eq />
<ci>Pcorla</ci>
<apply>
<minus />
<apply>
<divide />
<ci>Vcorla</ci>
<ci>Ccorla</ci>
</apply>
<apply>
<divide />
<apply>
<times />
<ci>Px1</ci>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
</apply>
<apply>
<minus />
<apply>
<exp />
<apply>
<divide />
<ci>Vcorla</ci>
<ci>Vx1</ci>
</apply>
</apply>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq />
<ci>Pcorlac</ci>
<apply>
<plus />
<ci>Pcorla</ci>
<ci>Pcorisfc</ci>
</apply>
</apply>
<apply>
<eq />
<ci>Pcorlv</ci>
<apply>
<minus />
<apply>
<divide />
<ci>Vcorlv</ci>
<ci>Ccorlv</ci>
</apply>
<apply>
<divide />
<apply>
<times />
<ci>Px1</ci>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
</apply>
<apply>
<minus />
<apply>
<exp />
<apply>
<divide />
<ci>Vcorlv</ci>
<ci>Vx1</ci>
</apply>
</apply>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq />
<ci>Pcorlvc</ci>
<apply>
<plus />
<ci>Pcorlv</ci>
<ci>Ppcdc</ci>
</apply>
</apply>
<apply>
<eq />
<ci>Pcorsa</ci>
<apply>
<minus />
<apply>
<divide />
<ci>Vcorsa</ci>
<ci>Ccorsa</ci>
</apply>
<apply>
<divide />
<apply>
<times />
<ci>Px1</ci>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
</apply>
<apply>
<minus />
<apply>
<exp />
<apply>
<divide />
<ci>Vcorsa</ci>
<ci>Vx1</ci>
</apply>
</apply>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq />
<ci>Pcorsac</ci>
<apply>
<plus />
<ci>Pcorsa</ci>
<ci>Pcorisfc</ci>
</apply>
</apply>
<apply>
<eq />
<ci>Pcorsv</ci>
<apply>
<minus />
<apply>
<divide />
<ci>Vcorsv</ci>
<ci>Ccorsv</ci>
</apply>
<apply>
<divide />
<apply>
<times />
<ci>Px1</ci>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
</apply>
<apply>
<minus />
<apply>
<exp />
<apply>
<divide />
<ci>Vcorsv</ci>
<ci>Vx1</ci>
</apply>
</apply>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq />
<ci>Pcorsvc</ci>
<apply>
<plus />
<ci>Pcorsv</ci>
<ci>Ppcdc</ci>
</apply>
</apply>
<apply>
<eq />
<ci>Pla</ci>
<apply>
<minus />
<apply>
<times />
<apply>
<minus />
<ci>Vla</ci>
<ci>Vlar</ci>
</apply>
<ci>Ela</ci>
</apply>
<apply>
<divide />
<apply>
<times />
<ci>Px2</ci>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
</apply>
<apply>
<minus />
<apply>
<exp />
<apply>
<divide />
<ci>Vla</ci>
<ci>Vx8</ci>
</apply>
</apply>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq />
<ci>Plac</ci>
<apply>
<plus />
<ci>Pla</ci>
<ci>Ppcdc</ci>
</apply>
</apply>
<apply>
<eq />
<ci>Plv</ci>
<apply>
<minus />
<apply>
<times />
<apply>
<minus />
<ci>Vlv</ci>
<ci>Vlvr</ci>
</apply>
<ci>Elv</ci>
</apply>
<apply>
<divide />
<apply>
<times />
<ci>Px2</ci>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
</apply>
<apply>
<minus />
<apply>
<exp />
<apply>
<divide />
<ci>Vlv</ci>
<ci>Vx8</ci>
</apply>
</apply>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq />
<ci>Plvc</ci>
<apply>
<plus />
<ci>Plv</ci>
<ci>Ppcdc</ci>
</apply>
</apply>
<apply>
<eq />
<ci>Ppa</ci>
<apply>
<minus />
<apply>
<divide />
<ci>Vpa</ci>
<ci>Cpa</ci>
</apply>
<apply>
<divide />
<apply>
<times />
<ci>Px2</ci>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
</apply>
<apply>
<minus />
<apply>
<exp />
<apply>
<divide />
<ci>Vpa</ci>
<ci>Vx8</ci>
</apply>
</apply>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq />
<ci>Ppac</ci>
<apply>
<plus />
<ci>Ppa</ci>
<ci>Pplc</ci>
</apply>
</apply>
<apply>
<eq />
<ci>Ppad</ci>
<apply>
<minus />
<ci>Ppadc</ci>
<ci>Pplc</ci>
</apply>
</apply>
<apply>
<eq />
<ci>Ppadc</ci>
<apply>
<minus />
<apply>
<plus />
<apply>
<times />
<apply>
<diff />
<bvar>
<ci>t</ci>
</bvar>
<ci>Vpad</ci>
</apply>
<ci>Rtpad</ci>
</apply>
<ci>Pplc</ci>
<apply>
<divide />
<ci>Vpad</ci>
<ci>Ctpad</ci>
</apply>
</apply>
<apply>
<divide />
<apply>
<times />
<ci>Px2</ci>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
</apply>
<apply>
<minus />
<apply>
<exp />
<apply>
<divide />
<ci>Vpad</ci>
<ci>Vx8</ci>
</apply>
</apply>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq />
<ci>Ppap</ci>
<apply>
<minus />
<ci>Ppapc</ci>
<ci>Pplc</ci>
</apply>
</apply>
<apply>
<eq />
<ci>Ppapc1</ci>
<apply>
<divide />
<apply>
<plus />
<apply>
<minus />
<apply>
<plus />
<apply>
<minus />
<apply>
<divide />
<apply>
<times />
<ci>Rpuv</ci>
<ci>Vpap</ci>
</apply>
<ci>Ctpap</ci>
</apply>
<apply>
<divide />
<apply>
<times />
<ci>Rpuv</ci>
<ci>Px2</ci>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
</apply>
<apply>
<minus />
<apply>
<exp />
<apply>
<divide />
<ci>Vpap</ci>
<ci>Vx8</ci>
</apply>
</apply>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
<apply>
<times />
<ci>Prvc</ci>
<ci>Rtpap</ci>
</apply>
</apply>
<apply>
<times />
<ci>Rpuv</ci>
<ci>Rtpap</ci>
<ci>Fpap</ci>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">16.666666666666668</cn>
</apply>
</apply>
<apply>
<times />
<ci>Pplc</ci>
<ci>Rpuv</ci>
</apply>
</apply>
<apply>
<plus />
<ci>Rtpap</ci>
<ci>Rpuv</ci>
</apply>
</apply>
</apply>
<apply>
<eq />
<ci>Ppapc2</ci>
<apply>
<minus />
<apply>
<minus />
<apply>
<plus />
<apply>
<divide />
<ci>Vpap</ci>
<ci>Ctpap</ci>
</apply>
<ci>Pplc</ci>
</apply>
<apply>
<times />
<ci>Rtpap</ci>
<ci>Fpap</ci>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">16.666666666666668</cn>
</apply>
</apply>
<apply>
<divide />
<apply>
<times />
<ci>Px2</ci>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
</apply>
<apply>
<minus />
<apply>
<exp />
<apply>
<divide />
<ci>Vpap</ci>
<ci>Vx8</ci>
</apply>
</apply>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq />
<ci>Ppapc</ci>
<piecewise>
<piece>
<ci>Ppapc1</ci>
<apply>
<gt />
<ci>Prvc</ci>
<ci>Ppapc1</ci>
</apply>
</piece>
<otherwise>
<ci>Ppapc2</ci>
</otherwise>
</piecewise>
</apply>
<apply>
<eq />
<ci>Ppc</ci>
<apply>
<minus />
<apply>
<divide />
<ci>Vpc</ci>
<ci>Cpc</ci>
</apply>
<apply>
<divide />
<apply>
<times />
<ci>Px2</ci>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
</apply>
<apply>
<minus />
<apply>
<exp />
<apply>
<divide />
<ci>Vpc</ci>
<ci>Vx8</ci>
</apply>
</apply>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq />
<ci>Ppcc</ci>
<apply>
<plus />
<ci>Ppc</ci>
<ci>Pplc</ci>
</apply>
</apply>
<apply>
<eq />
<ci>Ppcd</ci>
<apply>
<minus />
<apply>
<times />
<ci>K_pcd</ci>
<apply>
<exp />
<apply>
<divide />
<apply>
<minus />
<ci>Vpcd</ci>
<ci>Vpcd_o</ci>
</apply>
<ci>phi_pcd</ci>
</apply>
</apply>
</apply>
<apply>
<divide />
<apply>
<times />
<ci>Px2</ci>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
</apply>
<apply>
<minus />
<apply>
<exp />
<apply>
<divide />
<ci>Vpcd</ci>
<ci>Vx75</ci>
</apply>
</apply>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq />
<ci>Ppcdc</ci>
<apply>
<plus />
<ci>Ppcd</ci>
<ci>Pplc</ci>
</apply>
</apply>
<apply>
<eq />
<ci>Ppl</ci>
<apply>
<minus />
<ci>Pplc</ci>
<ci>Pbs</ci>
</apply>
</apply>
<apply>
<eq />
<ci>Ppv</ci>
<apply>
<minus />
<apply>
<divide />
<ci>Vpv</ci>
<ci>Cpv</ci>
</apply>
<apply>
<divide />
<apply>
<times />
<ci>Px2</ci>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
</apply>
<apply>
<minus />
<apply>
<exp />
<apply>
<divide />
<ci>Vpv</ci>
<ci>Vx8</ci>
</apply>
</apply>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq />
<ci>Ppvc</ci>
<apply>
<plus />
<ci>Ppv</ci>
<ci>Pplc</ci>
</apply>
</apply>
<apply>
<eq />
<ci>Pra</ci>
<apply>
<minus />
<apply>
<times />
<apply>
<minus />
<ci>Vra</ci>
<ci>Vrar</ci>
</apply>
<ci>Era</ci>
</apply>
<apply>
<divide />
<apply>
<times />
<ci>Px2</ci>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
</apply>
<apply>
<minus />
<apply>
<exp />
<apply>
<divide />
<ci>Vra</ci>
<ci>Vx8</ci>
</apply>
</apply>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq />
<ci>Prac</ci>
<apply>
<plus />
<ci>Pra</ci>
<ci>Ppcdc</ci>
</apply>
</apply>
<apply>
<eq />
<ci>Prv</ci>
<apply>
<minus />
<apply>
<times />
<apply>
<minus />
<ci>Vrv</ci>
<ci>Vrvr</ci>
</apply>
<ci>Erv</ci>
</apply>
<apply>
<divide />
<apply>
<times />
<ci>Px2</ci>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
</apply>
<apply>
<minus />
<apply>
<exp />
<apply>
<divide />
<ci>Vrv</ci>
<ci>Vx8</ci>
</apply>
</apply>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq />
<ci>Prvc</ci>
<apply>
<plus />
<ci>Prv</ci>
<ci>Ppcdc</ci>
</apply>
</apply>
<apply>
<eq />
<ci>Psa_a</ci>
<apply>
<times />
<ci>Kc</ci>
<apply>
<log />
<apply>
<plus />
<apply>
<divide />
<apply>
<minus />
<ci>Vsa</ci>
<ci>Vsa_o</ci>
</apply>
<ci>Do</ci>
</apply>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq />
<ci>Psa</ci>
<apply>
<plus />
<apply>
<times />
<ci>F_vaso</ci>
<ci>Psa_a</ci>
</apply>
<apply>
<times />
<apply>
<minus />
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
<ci>F_vaso</ci>
</apply>
<ci>Psa_p</ci>
</apply>
</apply>
</apply>
<apply>
<eq />
<ci>Psa_p</ci>
<apply>
<plus />
<apply>
<times />
<ci>Kp1</ci>
<apply>
<exp />
<apply>
<times />
<ci>tau_p</ci>
<apply>
<minus />
<ci>Vsa</ci>
<ci>Vsa_o</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<times />
<ci>Kp2</ci>
<apply>
<power />
<apply>
<minus />
<ci>Vsa</ci>
<ci>Vsa_o</ci>
</apply>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">2</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq />
<ci>Psap</ci>
<apply>
<minus />
<apply>
<divide />
<ci>Vsap</ci>
<ci>Csap</ci>
</apply>
<apply>
<divide />
<apply>
<times />
<ci>Px2</ci>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
</apply>
<apply>
<minus />
<apply>
<exp />
<apply>
<divide />
<ci>Vsap</ci>
<ci>Vx8</ci>
</apply>
</apply>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq />
<ci>Psc</ci>
<apply>
<minus />
<apply>
<divide />
<ci>Vsc</ci>
<ci>Csc</ci>
</apply>
<apply>
<divide />
<apply>
<times />
<ci>Px2</ci>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
</apply>
<apply>
<minus />
<apply>
<exp />
<apply>
<divide />
<ci>Vsc</ci>
<ci>Vx8</ci>
</apply>
</apply>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq />
<ci>Psv</ci>
<apply>
<times />
<ci>Kv</ci>
<apply>
<log />
<apply>
<minus />
<apply>
<divide />
<ci>Vmax_sv</ci>
<ci>Vsv</ci>
</apply>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">0.99</cn>
</apply>
</apply>
<apply>
<minus />
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
<apply>
<eq />
<ci>PulArtVol</ci>
<apply>
<plus />
<ci>Vpap</ci>
<ci>Vpad</ci>
<ci>Vpa</ci>
</apply>
</apply>
<apply>
<eq />
<ci>PulVenVol</ci>
<ci>Vpv</ci>
</apply>
<apply>
<eq />
<ci>Pvc</ci>
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<piece>
<apply>
<minus />
<apply>
<plus />
<ci>D2</ci>
<apply>
<times />
<ci>K2</ci>
<apply>
<exp />
<apply>
<divide />
<ci>Vo</ci>
<ci>Vmin_vc</ci>
</apply>
</apply>
</apply>
<apply>
<divide />
<apply>
<times />
<ci>K1</ci>
<apply>
<minus />
<ci>Vvc</ci>
<ci>Vo</ci>
</apply>
</apply>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="capacitance">1</cn>
</apply>
</apply>
<apply>
<divide />
<ci>Px2</ci>
<apply>
<minus />
<apply>
<exp />
<apply>
<divide />
<ci>Vvc</ci>
<ci>Vx8</ci>
</apply>
</apply>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
<apply>
<gt />
<ci>Vvc</ci>
<ci>Vo</ci>
</apply>
</piece>
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<apply>
<minus />
<apply>
<plus />
<ci>D2</ci>
<apply>
<times />
<ci>K2</ci>
<apply>
<exp />
<apply>
<divide />
<ci>Vvc</ci>
<ci>Vmin_vc</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<divide />
<ci>Px2</ci>
<apply>
<minus />
<apply>
<exp />
<apply>
<divide />
<ci>Vvc</ci>
<ci>Vx8</ci>
</apply>
</apply>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
</otherwise>
</piecewise>
</apply>
<apply>
<eq />
<ci>Pvcc</ci>
<apply>
<plus />
<ci>Pvc</ci>
<ci>Pplc</ci>
</apply>
</apply>
<apply>
<eq />
<ci>Rsa</ci>
<apply>
<plus />
<ci>Rsao</ci>
<apply>
<times />
<ci>Kr</ci>
<apply>
<exp />
<apply>
<times />
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">4</cn>
<ci>F_vaso</ci>
</apply>
</apply>
</apply>
<apply>
<times />
<ci>Kr</ci>
<apply>
<power />
<apply>
<divide />
<ci>Vsa_max</ci>
<ci>Vsa</ci>
</apply>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">2</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq />
<ci>Rvc</ci>
<apply>
<plus />
<apply>
<times />
<ci>KR</ci>
<apply>
<power />
<apply>
<divide />
<ci>Vmax_vc</ci>
<ci>Vvc</ci>
</apply>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">2</cn>
</apply>
</apply>
<ci>Ro</ci>
</apply>
</apply>
<apply>
<eq />
<ci>SV</ci>
<apply>
<times />
<apply>
<divide />
<ci>COutput</ci>
<ci>HR</ci>
</apply>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">60</cn>
</apply>
</apply>
<apply>
<eq />
<ci>SysArtVol</ci>
<apply>
<plus />
<ci>Vaop</ci>
<ci>Vaod</ci>
<ci>Vsa</ci>
<ci>Vsap</ci>
</apply>
</apply>
<apply>
<eq />
<ci>SysVenVol</ci>
<apply>
<plus />
<ci>Vsv</ci>
<ci>Vvc</ci>
</apply>
</apply>
<apply>
<eq />
<ci>VBcirc</ci>
<apply>
<minus />
<ci>Vtot</ci>
<ci>perifl</ci>
</apply>
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<eq />
<apply>
<diff />
<bvar>
<ci>t</ci>
</bvar>
<ci>Vaod</ci>
</apply>
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<times />
<apply>
<minus />
<apply>
<minus />
<ci>Faop</ci>
<apply>
<times />
<ci>Faod</ci>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">0.059999999999999984</cn>
</apply>
</apply>
<apply>
<times />
<ci>Fcrb</ci>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">0.059999999999999984</cn>
</apply>
</apply>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">16.66666666666667</cn>
</apply>
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<apply>
<eq />
<apply>
<diff />
<bvar>
<ci>t</ci>
</bvar>
<ci>Vaop</ci>
</apply>
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<divide />
<apply>
<plus />
<apply>
<minus />
<ci>Paopc</ci>
<apply>
<divide />
<ci>Vaop</ci>
<ci>Caop</ci>
</apply>
</apply>
<apply>
<divide />
<apply>
<times />
<ci>Px2</ci>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
</apply>
<apply>
<minus />
<apply>
<exp />
<apply>
<divide />
<ci>Vaop</ci>
<ci>Vx8</ci>
</apply>
</apply>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
<ci>Rtaop</ci>
</apply>
</apply>
<apply>
<eq />
<apply>
<diff />
<bvar>
<ci>t</ci>
</bvar>
<ci>Vcorao</ci>
</apply>
<apply>
<minus />
<apply>
<minus />
<apply>
<minus />
<ci>Flv</ci>
<apply>
<diff />
<bvar>
<ci>t</ci>
</bvar>
<ci>Vaop</ci>
</apply>
</apply>
<apply>
<times />
<ci>Faop</ci>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">16.66666666666667</cn>
</apply>
</apply>
<ci>Fcorao</ci>
</apply>
</apply>
<apply>
<eq />
<apply>
<diff />
<bvar>
<ci>t</ci>
</bvar>
<ci>Vcorcap</ci>
</apply>
<apply>
<minus />
<ci>Fcorsa</ci>
<ci>Fcorcap</ci>
</apply>
</apply>
<apply>
<eq />
<ci>Vcorcirc</ci>
<apply>
<plus />
<ci>Vcorao</ci>
<ci>Vcorea</ci>
<ci>Vcorla</ci>
<ci>Vcorsa</ci>
<ci>Vcorcap</ci>
<ci>Vcorsv</ci>
<ci>Vcorlv</ci>
<ci>Vcorev</ci>
</apply>
</apply>
<apply>
<eq />
<apply>
<diff />
<bvar>
<ci>t</ci>
</bvar>
<ci>Vcorea</ci>
</apply>
<apply>
<minus />
<ci>Fcorao</ci>
<ci>Fcorea</ci>
</apply>
</apply>
<apply>
<eq />
<apply>
<diff />
<bvar>
<ci>t</ci>
</bvar>
<ci>Vcorev</ci>
</apply>
<apply>
<minus />
<ci>Fcorlv</ci>
<ci>Fcorev</ci>
</apply>
</apply>
<apply>
<eq />
<apply>
<diff />
<bvar>
<ci>t</ci>
</bvar>
<ci>Vcorla</ci>
</apply>
<apply>
<minus />
<ci>Fcorea</ci>
<ci>Fcorla</ci>
</apply>
</apply>
<apply>
<eq />
<apply>
<diff />
<bvar>
<ci>t</ci>
</bvar>
<ci>Vcorlv</ci>
</apply>
<apply>
<minus />
<ci>Fcorsv</ci>
<ci>Fcorlv</ci>
</apply>
</apply>
<apply>
<eq />
<apply>
<diff />
<bvar>
<ci>t</ci>
</bvar>
<ci>Vcorsa</ci>
</apply>
<apply>
<minus />
<ci>Fcorla</ci>
<ci>Fcorsa</ci>
</apply>
</apply>
<apply>
<eq />
<apply>
<diff />
<bvar>
<ci>t</ci>
</bvar>
<ci>Vcorsv</ci>
</apply>
<apply>
<minus />
<ci>Fcorcap</ci>
<ci>Fcorsv</ci>
</apply>
</apply>
<apply>
<eq />
<apply>
<diff />
<bvar>
<ci>t</ci>
</bvar>
<ci>Vla</ci>
</apply>
<apply>
<minus />
<ci>Fpv</ci>
<ci>Fla</ci>
</apply>
</apply>
<apply>
<eq />
<ci>Vlar</ci>
<apply>
<plus />
<apply>
<times />
<apply>
<minus />
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
<ci>yla</ci>
</apply>
<apply>
<minus />
<ci>Vlard</ci>
<ci>Vlars</ci>
</apply>
</apply>
<ci>Vlars</ci>
</apply>
</apply>
<apply>
<eq />
<apply>
<diff />
<bvar>
<ci>t</ci>
</bvar>
<ci>Vlv</ci>
</apply>
<apply>
<minus />
<ci>Fla</ci>
<ci>Flv</ci>
</apply>
</apply>
<apply>
<eq />
<ci>Vlvr</ci>
<apply>
<plus />
<apply>
<times />
<apply>
<minus />
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
<ci>ylv</ci>
</apply>
<apply>
<minus />
<ci>Vlvrd</ci>
<ci>Vlvrs</ci>
</apply>
</apply>
<ci>Vlvrs</ci>
</apply>
</apply>
<apply>
<eq />
<apply>
<diff />
<bvar>
<ci>t</ci>
</bvar>
<ci>Vpa</ci>
</apply>
<apply>
<minus />
<apply>
<minus />
<ci>Fpad</ci>
<ci>Fps</ci>
</apply>
<ci>Fpa</ci>
</apply>
</apply>
<apply>
<eq />
<apply>
<diff />
<bvar>
<ci>t</ci>
</bvar>
<ci>Vpad</ci>
</apply>
<apply>
<times />
<apply>
<minus />
<ci>Fpap</ci>
<apply>
<times />
<ci>Fpad</ci>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">0.059999999999999984</cn>
</apply>
</apply>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">16.66666666666667</cn>
</apply>
</apply>
<apply>
<eq />
<apply>
<diff />
<bvar>
<ci>t</ci>
</bvar>
<ci>Vpap</ci>
</apply>
<apply>
<minus />
<ci>Frv</ci>
<apply>
<times />
<ci>Fpap</ci>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">16.66666666666667</cn>
</apply>
</apply>
</apply>
<apply>
<eq />
<apply>
<diff />
<bvar>
<ci>t</ci>
</bvar>
<ci>Vpc</ci>
</apply>
<apply>
<minus />
<ci>Fpa</ci>
<ci>Fpc</ci>
</apply>
</apply>
<apply>
<eq />
<ci>Vpcd</ci>
<apply>
<plus />
<ci>Vrv</ci>
<ci>Vra</ci>
<ci>Vlv</ci>
<ci>Vla</ci>
<ci>perifl</ci>
<ci>Vmyo</ci>
<ci>Vcorcirc</ci>
</apply>
</apply>
<apply>
<eq />
<apply>
<diff />
<bvar>
<ci>t</ci>
</bvar>
<ci>Vpv</ci>
</apply>
<apply>
<minus />
<apply>
<plus />
<ci>Fpc</ci>
<ci>Fps</ci>
</apply>
<ci>Fpv</ci>
</apply>
</apply>
<apply>
<eq />
<apply>
<diff />
<bvar>
<ci>t</ci>
</bvar>
<ci>Vra</ci>
</apply>
<apply>
<plus />
<apply>
<minus />
<ci>Fvc</ci>
<ci>Fra</ci>
</apply>
<ci>Fcorev</ci>
</apply>
</apply>
<apply>
<eq />
<ci>Vrar</ci>
<apply>
<plus />
<apply>
<times />
<apply>
<minus />
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
<ci>yra</ci>
</apply>
<apply>
<minus />
<ci>Vrard</ci>
<ci>Vrars</ci>
</apply>
</apply>
<ci>Vrars</ci>
</apply>
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<apply>
<eq />
<apply>
<diff />
<bvar>
<ci>t</ci>
</bvar>
<ci>Vrv</ci>
</apply>
<apply>
<minus />
<ci>Fra</ci>
<ci>Frv</ci>
</apply>
</apply>
<apply>
<eq />
<ci>Vrvr</ci>
<apply>
<plus />
<apply>
<times />
<apply>
<minus />
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
<ci>yrv</ci>
</apply>
<apply>
<minus />
<ci>Vrvrd</ci>
<ci>Vrvrs</ci>
</apply>
</apply>
<ci>Vrvrs</ci>
</apply>
</apply>
<apply>
<eq />
<apply>
<diff />
<bvar>
<ci>t</ci>
</bvar>
<ci>Vsa</ci>
</apply>
<apply>
<minus />
<ci>Fsap</ci>
<ci>Fsa</ci>
</apply>
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<apply>
<eq />
<apply>
<diff />
<bvar>
<ci>t</ci>
</bvar>
<ci>Vsap</ci>
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<apply>
<minus />
<ci>Faod</ci>
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</apply>
</apply>
<apply>
<eq />
<apply>
<diff />
<bvar>
<ci>t</ci>
</bvar>
<ci>Vsc</ci>
</apply>
<apply>
<minus />
<ci>Fsa</ci>
<ci>Fsc</ci>
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<apply>
<eq />
<apply>
<diff />
<bvar>
<ci>t</ci>
</bvar>
<ci>Vsv</ci>
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<apply>
<minus />
<ci>Fsc</ci>
<ci>Fsv</ci>
</apply>
</apply>
<apply>
<eq />
<ci>Vtot</ci>
<apply>
<plus />
<ci>Vra</ci>
<ci>Vrv</ci>
<ci>Vpap</ci>
<ci>Vpad</ci>
<ci>Vpa</ci>
<ci>Vpc</ci>
<ci>Vpv</ci>
<ci>Vla</ci>
<ci>Vlv</ci>
<ci>Vaop</ci>
<ci>Vaod</ci>
<ci>Vsa</ci>
<ci>Vsap</ci>
<ci>Vsc</ci>
<ci>Vsv</ci>
<ci>Vvc</ci>
<ci>perifl</ci>
<ci>Vcorcirc</ci>
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</apply>
<apply>
<eq />
<apply>
<diff />
<bvar>
<ci>t</ci>
</bvar>
<ci>Vvc</ci>
</apply>
<apply>
<minus />
<apply>
<plus />
<ci>Fsv</ci>
<ci>Fcrb</ci>
</apply>
<ci>Fvc</ci>
</apply>
</apply>
</math>
</component>
<rdf:RDF xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:j.0="http://www.example.org/foo/bar/" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:ro="http://www.obofoundry.org/ro/ro.owl#" xmlns:opb="http://bhi.washington.edu/OPB#" xmlns:j.1="http://imc.org/vCard/3.0#">
<rdf:Description rdf:about="#lpc.Psa_p">
<dcterms:description>Passive systemic arterial pressure component</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Kp2">
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<dcterms:description>Pulmonary capillaries flow</dcterms:description>
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<dcterms:description>Transmural pericardial pressure</dcterms:description>
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<dcterms:description>Proximal pulmonary chamber arterial pressure</dcterms:description>
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<dcterms:description>Mean arterial blood pressure</dcterms:description>
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<dcterms:description>Passive vasomotor tone scaling parameter for systemic arterial pressure</dcterms:description>
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<rdf:Description rdf:about="#lpc.Caop">
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<rdf:Description rdf:about="#entity_67">
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<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00154" />
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<dcterms:description>Volume of blood in coronary circulation</dcterms:description>
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<rdf:Description rdf:about="#lpc.Vpv">
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<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00154" />
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<dcterms:description>Pulmonary veins volume</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Tsa">
<dcterms:description>Discrete systolic interval for atria</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Vsap">
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<ro:part_of>
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<dcterms:description>Proximal systemic arteries volume</dcterms:description>
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<rdf:Description rdf:about="#lpc.Paodc">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_98">
<semsim:physicalPropertyOf>
<rdf:Description rdf:about="#entity_56">
<ro:part_of>
<rdf:Description rdf:about="#entity_45">
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_87209" />
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</semsim:physicalPropertyOf>
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<dcterms:description>Distal aorta chamber pressure</dcterms:description>
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<dcterms:description>Compliance of distal epicardial arteries</dcterms:description>
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<rdf:Description rdf:about="#lpc.Rpa">
<dcterms:description>Pulmonary arterioles resistance</dcterms:description>
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<rdf:Description rdf:about="#lpc.Vrard">
<dcterms:description>Unstressed end-diastolic right atrium volume</dcterms:description>
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<rdf:Description rdf:about="#lpc.Rcorlv">
<dcterms:description>Large coronary veins resistance</dcterms:description>
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<rdf:Description rdf:about="#lpc.Vrvrd">
<dcterms:description>Unstressed end-diastolic right ventricle volume</dcterms:description>
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<rdf:Description rdf:about="#lpc.Vrar">
<dcterms:description>Unstressed right atrial volume</dcterms:description>
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<rdf:Description rdf:about="#lpc.Ppac">
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<rdf:Description rdf:about="#property_78">
<semsim:physicalPropertyOf>
<rdf:Description rdf:about="#entity_7">
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<rdf:Description rdf:about="#entity_8">
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_279896" />
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<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_9670" />
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<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00509" />
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<dcterms:description>Pulmonary arterioles chamber pressure</dcterms:description>
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<rdf:Description rdf:about="#lpc.Paod">
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<rdf:Description rdf:about="#property_50">
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<rdf:Description rdf:about="#entity_44">
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<dcterms:description>Distal aorta transmural pressure</dcterms:description>
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<rdf:Description rdf:about="#lpc.Rsa">
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<rdf:Description rdf:about="#property_69">
<semsim:physicalPropertyOf>
<rdf:Description rdf:about="#entity_57">
<ro:part_of rdf:resource="#entity_8" />
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_74653" />
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</semsim:physicalPropertyOf>
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00509" />
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</semsim:isComputationalComponentFor>
<dcterms:description>Pulmonary arterioles transmural pressure</dcterms:description>
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<rdf:Description rdf:about="#lpc.Vmyo">
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<rdf:Description rdf:about="#property_70">
<semsim:physicalPropertyOf>
<rdf:Description rdf:about="#entity_58">
<ro:part_of>
<rdf:Description rdf:about="#entity_59">
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_9462" />
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</ro:part_of>
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_9670" />
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</semsim:physicalPropertyOf>
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00154" />
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</semsim:isComputationalComponentFor>
<dcterms:description>Myocardium blood volume</dcterms:description>
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<rdf:Description rdf:about="#lpc.trelv">
<dcterms:description>Time from start of ventricular contraction cycle</dcterms:description>
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<rdf:Description rdf:about="#lpc.Vsv">
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<rdf:Description rdf:about="#property_32">
<semsim:physicalPropertyOf>
<rdf:Description rdf:about="#entity_1">
<ro:part_of>
<rdf:Description rdf:about="#entity_2">
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_45626" />
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</ro:part_of>
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_9670" />
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</semsim:physicalPropertyOf>
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00154" />
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</semsim:isComputationalComponentFor>
<dcterms:description>Systemic veins volume</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Vcorea">
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<rdf:Description rdf:about="#property_51">
<semsim:physicalPropertyOf>
<rdf:Description rdf:about="#entity_46">
<ro:part_of>
<rdf:Description rdf:about="#entity_47">
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_279921" />
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</ro:part_of>
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_9670" />
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</semsim:physicalPropertyOf>
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00154" />
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</semsim:isComputationalComponentFor>
<dcterms:description>Distal epicardial arteries volume</dcterms:description>
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<rdf:Description rdf:about="#lpc.Ppcdc">
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<rdf:Description rdf:about="#property_20">
<semsim:physicalPropertyOf>
<rdf:Description rdf:about="#entity_14">
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_11350" />
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</semsim:physicalPropertyOf>
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00509" />
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</semsim:isComputationalComponentFor>
<dcterms:description>Pericardial chamber pressure</dcterms:description>
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<rdf:Description rdf:about="#lpc.Fsap">
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<rdf:Description rdf:about="#property_59">
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00299" />
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</semsim:isComputationalComponentFor>
<dcterms:description>Proximal systemic arteries flow</dcterms:description>
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<dcterms:description>Right atrium activation function</dcterms:description>
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<rdf:Description rdf:about="#lpc.Rpad">
<dcterms:description>Distal proximal pulmonary resistance</dcterms:description>
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<rdf:Description rdf:about="#lpc.Pcorla">
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<rdf:Description rdf:about="#property_46">
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00509" />
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</semsim:isComputationalComponentFor>
<dcterms:description>Large coronary arteries transmural pressure</dcterms:description>
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<rdf:Description rdf:about="#lpc.Flv">
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<rdf:Description rdf:about="#property_75">
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00299" />
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</semsim:isComputationalComponentFor>
<dcterms:description>Flow across aortic valve</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Emaxra">
<dcterms:description>Maximum elastance right atrium</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Emaxlv">
<dcterms:description>Maximum elastance of first left ventricle component</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Ccorlv">
<dcterms:description>Compliance of large coronary veins</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Rcorsa">
<dcterms:description>Small coronary arteries resistance</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Rra">
<dcterms:description>Fluid resistance in the right atrium</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Rsc">
<dcterms:description>Systemic capillaries resistance</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Ccorsa">
<dcterms:description>Compliance of small coronary arteries</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Vrv">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_26">
<semsim:physicalPropertyOf>
<rdf:Description rdf:about="#entity_20">
<ro:part_of>
<rdf:Description rdf:about="#entity_21">
<ro:part_of>
<rdf:Description rdf:about="#entity_19">
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_7088" />
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</ro:part_of>
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_7098" />
</rdf:Description>
</ro:part_of>
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_9670" />
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</semsim:physicalPropertyOf>
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00154" />
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</semsim:isComputationalComponentFor>
<dcterms:description>Fluid volume in the right ventricle</dcterms:description>
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<rdf:Description rdf:about="#lpc.Ccorcap">
<dcterms:description>Compliance of coronary capillaries</dcterms:description>
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<rdf:Description rdf:about="#lpc.Pcoraoc">
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<rdf:Description rdf:about="#property_48">
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<rdf:Description rdf:about="#entity_40">
<ro:part_of>
<rdf:Description rdf:about="#entity_41">
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_279851" />
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</ro:part_of>
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_9670" />
</rdf:Description>
</semsim:physicalPropertyOf>
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00509" />
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</semsim:isComputationalComponentFor>
<dcterms:description>Proximal epicardial arteries chamber pressure</dcterms:description>
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<rdf:Description rdf:about="#lpc.Fpa">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_3">
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00299" />
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</semsim:isComputationalComponentFor>
<dcterms:description>Pulmonary arterioles flow</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Raop">
<dcterms:description>Proximal aortic resistance</dcterms:description>
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<rdf:Description rdf:about="#lpc.Px1">
<dcterms:description>P-V curve shaping parameter</dcterms:description>
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<rdf:Description rdf:about="#lpc.Ppc">
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<rdf:Description rdf:about="#property_76">
<semsim:physicalPropertyOf>
<rdf:Description rdf:about="#entity_63">
<ro:part_of>
<rdf:Description rdf:about="#entity_10">
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_14121" />
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</ro:part_of>
<semsim:name>Wall of capillary</semsim:name>
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</semsim:physicalPropertyOf>
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<dcterms:description>Pulmonary capillaries transmural pressure</dcterms:description>
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<rdf:Description rdf:about="http://www.cellml.org/cellml/1.0#heldt_lpc_2002">
<dc:title>The Heldt et al. 2002 computational model of the heart</dc:title>
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<rdf:value>This is the CellML description of Heldt et al.'s computational model of the heart. Specifically the left ventricle.</rdf:value>
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<vCard:FN>Catherine Lloyd</vCard:FN>
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</cmeta:comment>
<cmeta:bio_entity>left ventricle</cmeta:bio_entity>
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<bqs:subject_type>keyword</bqs:subject_type>
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<rdf:Bag>
<rdf:li>lumped parameter</rdf:li>
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<bqs:reference rdf:parseType="Resource">
<bqs:Pubmed_id>11842064</bqs:Pubmed_id>
<bqs:JournalArticle rdf:parseType="Resource">
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<rdf:Seq>
<rdf:li rdf:parseType="Resource">
<bqs:Person rdf:parseType="Resource">
<vCard:N vCard:Family="Heldt" vCard:Given="T" />
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</rdf:li>
<rdf:li rdf:parseType="Resource">
<bqs:Person rdf:parseType="Resource">
<vCard:N vCard:Family="Shim" vCard:Given="E" vCard:Other="B" />
</bqs:Person>
</rdf:li>
<rdf:li rdf:parseType="Resource">
<bqs:Person rdf:parseType="Resource">
<vCard:N vCard:Family="Kamm" vCard:Given="R" vCard:Other="D" />
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</rdf:li>
<rdf:li rdf:parseType="Resource">
<bqs:Person rdf:parseType="Resource">
<vCard:N vCard:Family="Mark" vCard:Given="R" vCard:Other="G" />
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</dc:creator>
<dc:title>Computational modeling of cardiovascular response to orthostatic stress</dc:title>
<dcterms:issued dcterms:W3CDTF="2002" />
<bqs:Journal rdf:parseType="Resource">
<dc:title>Journal of Applied Physiology</dc:title>
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<bqs:volume>92</bqs:volume>
<bqs:first_page>1239</bqs:first_page>
<bqs:last_page>1254</bqs:last_page>
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</bqs:reference>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Pcorev">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_81">
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00509" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Epicardial veins transmural pressure</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.phi_pcd">
<dcterms:description>Pericardial P-V curve parameter</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Prvc">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_84">
<semsim:physicalPropertyOf rdf:resource="#entity_20" />
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00509" />
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</semsim:isComputationalComponentFor>
<dcterms:description>Right ventricular chamber pressure</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.SV">
<dcterms:description>Stroke volume (COutput/HR)</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Ppcc">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_96">
<semsim:physicalPropertyOf>
<rdf:Description rdf:about="#entity_9">
<ro:part_of rdf:resource="#entity_10" />
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_9670" />
</rdf:Description>
</semsim:physicalPropertyOf>
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00509" />
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</semsim:isComputationalComponentFor>
<dcterms:description>Pulmonary capillaries chamber pressure</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Vcorev">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_61">
<semsim:physicalPropertyOf>
<rdf:Description rdf:about="#entity_53">
<ro:part_of>
<rdf:Description rdf:about="#entity_54">
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_279902" />
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</ro:part_of>
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_9670" />
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</semsim:physicalPropertyOf>
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00154" />
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</semsim:isComputationalComponentFor>
<dcterms:description>Epicardial veins volume</dcterms:description>
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<rdf:Description rdf:about="#lpc.Vlars">
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<rdf:Description rdf:about="#lpc.Faod">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_66">
<semsim:physicalPropertyOf>
<rdf:Description rdf:about="#process_0" dcterms:description="">
<semsim:hasMediatorParticipant>
<rdf:Description rdf:about="#mediator_0">
<semsim:hasPhysicalEntityReference rdf:resource="#entity_44" />
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</semsim:hasMediatorParticipant>
<semsim:hasSinkParticipant>
<rdf:Description rdf:about="#sink_0" semsim:hasMultiplier="1.0">
<semsim:hasPhysicalEntityReference rdf:resource="#entity_42" />
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</semsim:hasSinkParticipant>
<semsim:hasSourceParticipant>
<rdf:Description rdf:about="#source_0" semsim:hasMultiplier="1.0">
<semsim:hasPhysicalEntityReference>
<rdf:Description rdf:about="#entity_33">
<ro:part_of>
<rdf:Description rdf:about="#entity_34">
<semsim:name>Proximal zone of aorta</semsim:name>
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</ro:part_of>
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</semsim:hasPhysicalEntityReference>
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</semsim:hasSourceParticipant>
<semsim:name>Blood flow through the distal aorta</semsim:name>
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</semsim:isComputationalComponentFor>
<dcterms:description>Distal aorta flow</dcterms:description>
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<rdf:Description rdf:about="#lpc.PulArtVol">
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<rdf:Description rdf:about="#property_90">
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<rdf:Description rdf:about="#entity_70">
<ro:part_of>
<rdf:Description rdf:about="#entity_71">
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_45842" />
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</ro:part_of>
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_9670" />
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</semsim:physicalPropertyOf>
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00154" />
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<dcterms:description>Pulmonary arterial volume</dcterms:description>
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<rdf:Description rdf:about="#lpc.Pcorao">
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<semsim:physicalPropertyOf>
<rdf:Description rdf:about="#entity_52">
<ro:part_of rdf:resource="#entity_41" />
<semsim:name>Wall of artery</semsim:name>
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<dcterms:description>Proximal epicardial arteries transmural pressure</dcterms:description>
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<rdf:Description rdf:about="#lpc.Rcorea">
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<rdf:Description rdf:about="#lpc.Psap">
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<rdf:Description rdf:about="#property_49">
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<dcterms:description>Proximal systemic arteries pressure</dcterms:description>
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<rdf:Description rdf:about="#lpc.Pcorcap">
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<rdf:Description rdf:about="#entity_28">
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<rdf:Description rdf:about="#entity_23">
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<dcterms:description>Coronary capillary transmural pressure</dcterms:description>
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<rdf:Description rdf:about="#lpc.Vsa">
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<rdf:Description rdf:about="#property_28">
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<rdf:Description rdf:about="#entity_24">
<ro:part_of>
<rdf:Description rdf:about="#entity_25">
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_45623" />
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<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_9670" />
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<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00154" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Volume of systemic arteries</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Ro">
<dcterms:description>Vena cava resistance offset parameter</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Rtpad">
<dcterms:description>Distal pulmonary arterial transmural resistance</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Laop">
<dcterms:description>Proximal aorta inertance</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.TsvK">
<dcterms:description>Scaler to set ventricular systolic fraction of heart cycle</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Pcorisfc">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_94">
<semsim:physicalPropertyOf>
<rdf:Description rdf:about="#entity_74">
<ro:part_of>
<rdf:Description rdf:about="#entity_75">
<ro:part_of rdf:resource="#entity_59" />
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_17555" />
</rdf:Description>
</ro:part_of>
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_280556" />
</rdf:Description>
</semsim:physicalPropertyOf>
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00509" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Myocardium interstitial fluid pressure</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Ppl">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_72">
<semsim:physicalPropertyOf>
<rdf:Description rdf:about="#entity_60">
<ro:part_of>
<rdf:Description rdf:about="#entity_61">
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_17530" />
</rdf:Description>
</ro:part_of>
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_9740" />
</rdf:Description>
</semsim:physicalPropertyOf>
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00509" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Transmural pleural pressure</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Fcrb">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_58">
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00299" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Cerebral flow</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Ctpad">
<dcterms:description>Distal pulmonary arterial compliance</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Cpv">
<dcterms:description>Pulmonary veins compliance</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Vcorla">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_45">
<semsim:physicalPropertyOf>
<rdf:Description rdf:about="#entity_38">
<ro:part_of>
<rdf:Description rdf:about="#entity_39">
<semsim:name>Large coronary arteries</semsim:name>
</rdf:Description>
</ro:part_of>
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_9670" />
</rdf:Description>
</semsim:physicalPropertyOf>
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00154" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Large coronary arteries volume</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Vlv">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_80">
<semsim:physicalPropertyOf>
<rdf:Description rdf:about="#entity_49">
<ro:part_of>
<rdf:Description rdf:about="#entity_50">
<ro:part_of rdf:resource="#entity_19" />
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_7101" />
</rdf:Description>
</ro:part_of>
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_9670" />
</rdf:Description>
</semsim:physicalPropertyOf>
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00154" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Blood volume in the left ventricle</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Psv">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_1">
<semsim:physicalPropertyOf rdf:resource="#entity_1" />
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00509" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Systemic veins pressure</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Ppvc">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_13">
<semsim:physicalPropertyOf rdf:resource="#entity_3" />
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00509" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Pulmonary veins chamber pressure</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.D2">
<dcterms:description>Offsetting constant for partially collapsed vena cava pressure</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Rtaop">
<dcterms:description>Transmural proximal aortic resistance</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Vsc">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_29">
<semsim:physicalPropertyOf>
<rdf:Description rdf:about="#entity_26">
<ro:part_of>
<rdf:Description rdf:about="#entity_27">
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_279935" />
</rdf:Description>
</ro:part_of>
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_9670" />
</rdf:Description>
</semsim:physicalPropertyOf>
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00154" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Systemic capillaries volume</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Rla">
<dcterms:description>Fluid resistance in the left atrium</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Vra">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_22">
<semsim:physicalPropertyOf>
<rdf:Description rdf:about="#entity_17">
<ro:part_of>
<rdf:Description rdf:about="#entity_18">
<ro:part_of rdf:resource="#entity_19" />
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_7096" />
</rdf:Description>
</ro:part_of>
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_9670" />
</rdf:Description>
</semsim:physicalPropertyOf>
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00154" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Fluid volume in the right atrium</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Lpad">
<dcterms:description>Distal pulmonary artery inertance</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Vpap">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_93">
<semsim:physicalPropertyOf rdf:resource="#entity_15" />
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00154" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Proximal pulmonary arterial volume</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Pbs">
<dcterms:description>Reference pressure at body surface (ground)</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Kc">
<dcterms:description>Active vasomotor tone scaling parameter for systemic arterial pressure</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.VBcirc">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_74">
<semsim:physicalPropertyOf>
<rdf:Description rdf:about="#entity_62">
<ro:part_of>
<rdf:Description rdf:about="#entity_32">
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_256135" />
</rdf:Description>
</ro:part_of>
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_9670" />
</rdf:Description>
</semsim:physicalPropertyOf>
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00154" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Total blood in circulation</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Fcorsa">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_12">
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00299" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Small coronary arteries flow</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Pcorsv">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_105">
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00509" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Small coronary veins transmural pressure</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Fpap">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_104">
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00299" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Proximal pulmonary arterial flow</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="http://www.cellml.org/cellml/1.0">
<dc:creator rdf:parseType="Resource">
<vCard:N vCard:Family="Cumin" vCard:Given="David" />
<vCard:EMAIL rdf:value="d.cumin@auckland.ac.nz" rdf:type="http://imc.org/vCard/3.0#internet" />
<vCard:ORG rdf:parseType="Resource">
<vCard:Orgname>Auckland Bioengineering Institute</vCard:Orgname>
</vCard:ORG>
</dc:creator>
<dcterms:created dcterms:W3CDTF="2009-10-26" />
</rdf:Description>
<rdf:Description rdf:about="#lpc.Vcorsv">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_107">
<semsim:physicalPropertyOf>
<rdf:Description rdf:about="#entity_78">
<ro:part_of>
<rdf:Description rdf:about="#entity_79">
<semsim:name>Small coronary veins</semsim:name>
</rdf:Description>
</ro:part_of>
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_9670" />
</rdf:Description>
</semsim:physicalPropertyOf>
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00154" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Small coronary veins volume</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Vvc">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_43">
<semsim:physicalPropertyOf>
<rdf:Description rdf:about="#entity_13">
<ro:part_of>
<rdf:Description rdf:about="#entity_12">
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_321896" />
</rdf:Description>
</ro:part_of>
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_9670" />
</rdf:Description>
</semsim:physicalPropertyOf>
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00154" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Vena cava volume</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.K_pcd">
<dcterms:description>Scaling parameter for pericardial P-V curve</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Rpc">
<dcterms:description>Pulmonary capillaries resistance</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Pla">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_56">
<semsim:physicalPropertyOf>
<rdf:Description rdf:about="#entity_51">
<ro:part_of rdf:resource="#entity_19" />
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_9531" />
</rdf:Description>
</semsim:physicalPropertyOf>
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00509" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Pressure in the left atrium</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Raod">
<dcterms:description>Distal aortic resistance</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Fcorlv">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_95">
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00299" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Large coronary veins flow</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Vrvr">
<dcterms:description>Unstressed right ventricular volume</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.yrv">
<dcterms:description>Right ventricle activation function</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Do">
<dcterms:description>Active vasomotor tone volume parameter for systemic arterial pressure</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Ela">
<dcterms:description>Left atrial elastance</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Pcorsvc">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_53">
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00509" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Small coronary veins chamber pressure</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Pcoreac">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_14">
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00509" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Distal epicardial arteries chamber pressure</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Eminlv">
<dcterms:description>Minimum elastance of first left ventricle component</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Eminra">
<dcterms:description>Maximum elastance right ventricle</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Fla">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_68">
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00299" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Flow across mitral valve</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Vlvrs">
<dcterms:description>Unstressed end-systolic left ventricle volume</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Vcorao">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_82">
<semsim:physicalPropertyOf rdf:resource="#entity_40" />
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00154" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Proximal epicardial arteries volume</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.trela">
<dcterms:description>Time from start of atrial contraction cycle</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Plac">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_37">
<semsim:physicalPropertyOf>
<rdf:Description rdf:about="#entity_29">
<ro:part_of>
<rdf:Description rdf:about="#entity_30">
<ro:part_of rdf:resource="#entity_19" />
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_7097" />
</rdf:Description>
</ro:part_of>
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_9670" />
</rdf:Description>
</semsim:physicalPropertyOf>
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00509" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Left atrial chamber pressure</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Ccorla">
<dcterms:description>Compliance of large coronary arteries</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Ppapc2">
<dcterms:description>Proximal pulmonary artery chamber pressure (diastolic)</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Fpad">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_102">
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00299" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Distal pulmonary arterial flow</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Fps">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_9">
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00299" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Pulmonary shunt flow</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Lpa">
<dcterms:description>Pulmonary arterial inertance</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Ppv">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_85">
<semsim:physicalPropertyOf>
<rdf:Description rdf:about="#entity_66">
<ro:part_of rdf:resource="#entity_4" />
<semsim:name>Wall of vein</semsim:name>
</rdf:Description>
</semsim:physicalPropertyOf>
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00509" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Pulmonary veins transmural pressure</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Rsv">
<dcterms:description>Systemic veins resistance</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Vx1">
<dcterms:description>P-V curve shaping parameter</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.PRint">
<dcterms:description>Difference in atrial, venticular activation times</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Vpc">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_10">
<semsim:physicalPropertyOf rdf:resource="#entity_9" />
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00154" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Pulmonary capillaries volume</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Ppapc1">
<dcterms:description>Proximal pulmonary artery chamber pressure (systolic)</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Rcorsv">
<dcterms:description>Small coronary veins resistance</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Frv">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_23">
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00299" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Flow across pulmonary valve</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Vo">
<dcterms:description>Unstressed blood volume of vena cava</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.ylv">
<dcterms:description>Left ventricle activation function</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.yra">
<dcterms:description>Right ventricle activation function</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Rsap">
<dcterms:description>Prox. systemic arteries resistance</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.HR">
<dcterms:description>Heart Rate</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Pvcc">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_19">
<semsim:physicalPropertyOf rdf:resource="#entity_13" />
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00509" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Vena cava chamber pressure</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Vmax_vc">
<dcterms:description>Maximum volume of vena cava</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Pvc">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_16">
<semsim:physicalPropertyOf>
<rdf:Description rdf:about="#entity_11">
<ro:part_of rdf:resource="#entity_12" />
<semsim:name>Wall of artery</semsim:name>
</rdf:Description>
</semsim:physicalPropertyOf>
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00509" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Vena cava transmural pressure</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Emaxla">
<dcterms:description>Maximum elastance left atrium</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Eminla">
<dcterms:description>Minimum elastance left atrium</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Vrars">
<dcterms:description>Unstressed end-systolic right atrium volume</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Laod">
<dcterms:description>Distal aorta inertance</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Pcorea">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_87">
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00509" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Distal epicardial arteries transmural pressure</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Vaop">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_63">
<semsim:physicalPropertyOf rdf:resource="#entity_33" />
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00154" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Proximal aorta volume</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Rtpap">
<dcterms:description>Proximal pulmonary arterial transmural resistance</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Rcorao">
<dcterms:description>Proximal epicardial arteries resistance</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Pcorlvc">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_41">
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00509" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Large coronary veins chamber pressure</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Rcrb">
<dcterms:description>Cerebral circulation resistance</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Csc">
<dcterms:description>Systemic capillaries compliance</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.PulVenVol">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_6">
<semsim:physicalPropertyOf rdf:resource="#entity_3" />
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00154" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Pulmonary venous volume</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.tau_p">
<dcterms:description>Passive vasomotor tone constant for systemic arterial pressure</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Psa_a">
<dcterms:description>Active systemic arterial pressure component</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.COutput">
<dcterms:description>Cardiac output</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Erv">
<dcterms:description>Right ventricular elastance</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Prv">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_103">
<semsim:physicalPropertyOf>
<rdf:Description rdf:about="#entity_77">
<ro:part_of rdf:resource="#entity_19" />
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_9533" />
</rdf:Description>
</semsim:physicalPropertyOf>
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00509" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Blood pressure in the right ventricle</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.K2">
<dcterms:description>Scaling constant for partially collapsed Vena cava pressure</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Vlar">
<dcterms:description>Unstressed left atrial volume</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Pplc">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_44">
<semsim:physicalPropertyOf>
<rdf:Description rdf:about="#entity_37">
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_9740" />
</rdf:Description>
</semsim:physicalPropertyOf>
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00509" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Pleural chamber pressure</dcterms:description>
</rdf:Description>
<j.0:bazfoo />
<rdf:Description rdf:about="#lpc.Paopc">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_39">
<semsim:physicalPropertyOf rdf:resource="#entity_33" />
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00509" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Proximal aorta chamber pressure</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Vrvrs">
<dcterms:description>Unstressed end-systolic right ventricle volume</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Pcorsac">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_31">
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00509" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Small coronary arteries chamber pressure</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Rcorev">
<dcterms:description>Epicardial veins resistance</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.t">
<dcterms:description>Time - Solution domain</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Plvc">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_55">
<semsim:physicalPropertyOf rdf:resource="#entity_49" />
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00509" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Left ventricular chamber pressure</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Ccorev">
<dcterms:description>Compliance of epicardial veins</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Rsao">
<dcterms:description>Arteriolar resistance offset</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Kv">
<dcterms:description>Scaling factor for systemic venous pressure</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Vsa_o">
<dcterms:description>Minimal volume of systemic arteries</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Fcorea">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_47">
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00299" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Distal epicardial arteries flow</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Vpa">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_8">
<semsim:physicalPropertyOf rdf:resource="#entity_7" />
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00154" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Pulmonary arterioles volume</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Fsv">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_30">
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00299" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Systemic veins flow</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Ccorao">
<dcterms:description>Compliance of proximal epicardial arteries</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Vtot">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_38">
<semsim:physicalPropertyOf>
<rdf:Description rdf:about="#entity_31">
<ro:part_of rdf:resource="#entity_32" />
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_280556" />
</rdf:Description>
</semsim:physicalPropertyOf>
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00154" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Total blood volume</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Pcorsa">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_92">
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00509" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Small coronary arteries transmural pressure</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Ppap">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_83">
<semsim:physicalPropertyOf>
<rdf:Description rdf:about="#entity_65">
<ro:part_of rdf:resource="#entity_16" />
<semsim:name>Wall of artery</semsim:name>
</rdf:Description>
</semsim:physicalPropertyOf>
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00509" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Proximal pulmonary arterial transmural pressure</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Vpad">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_97">
<semsim:physicalPropertyOf>
<rdf:Description rdf:about="#entity_35">
<ro:part_of>
<rdf:Description rdf:about="#entity_36">
<semsim:name>Distal pulmonary arteries</semsim:name>
</rdf:Description>
</ro:part_of>
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_9670" />
</rdf:Description>
</semsim:physicalPropertyOf>
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00154" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Distal pulmonary arterial volume</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Rcorla">
<dcterms:description>Large coronary arteries resistance</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Psc">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_101">
<semsim:physicalPropertyOf rdf:resource="#entity_26" />
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00509" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Systemic capillaries pressure</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Rvc">
<dcterms:description>Resistance of Vena cava</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Pra">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_89">
<semsim:physicalPropertyOf>
<rdf:Description rdf:about="#entity_69">
<ro:part_of rdf:resource="#entity_19" />
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_9457" />
</rdf:Description>
</semsim:physicalPropertyOf>
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00509" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Pressure in the right atrium</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Plv">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_62">
<semsim:physicalPropertyOf>
<rdf:Description rdf:about="#entity_55">
<ro:part_of rdf:resource="#entity_19" />
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_9556" />
</rdf:Description>
</semsim:physicalPropertyOf>
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00509" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Pressure in the left ventricle</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Vlvrd">
<dcterms:description>Unstressed end-diastolic left ventricle volume</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Elv">
<dcterms:description>Left ventricular elastance</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Vpcd_o">
<dcterms:description>Pericardial P-V curve parameter</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Fcorla">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_88">
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00299" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Large coronary arteries flow</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Rcorcap">
<dcterms:description>Coronary capillaries resistance</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Fsa">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_24">
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00299" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Systemic arteries flow</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Pcorevc">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_35">
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00509" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Epicardial veins chamber pressure</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Vcorcap">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_79">
<semsim:physicalPropertyOf>
<rdf:Description rdf:about="#entity_22">
<ro:part_of rdf:resource="#entity_23" />
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_9670" />
</rdf:Description>
</semsim:physicalPropertyOf>
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00154" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Coronary capillaries volume</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Vcorsa">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_91">
<semsim:physicalPropertyOf>
<rdf:Description rdf:about="#entity_72">
<ro:part_of>
<rdf:Description rdf:about="#entity_73">
<semsim:name>Small coronary arteries</semsim:name>
</rdf:Description>
</ro:part_of>
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_9670" />
</rdf:Description>
</semsim:physicalPropertyOf>
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00154" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Small coronary arteries volume</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Pcorlv">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_36">
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00509" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Large coronary veins transmural pressure</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Ppadc">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_42">
<semsim:physicalPropertyOf rdf:resource="#entity_35" />
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00509" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Distal pulmonary arterial chamber pressure</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Rpap">
<dcterms:description>Proximal pulmonary resistance</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Cpc">
<dcterms:description>Pulmonary capillaries compliance</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Vlard">
<dcterms:description>Unstressed end-diastolic left atrium volume</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Era">
<dcterms:description>Right atrial elastance</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Emaxrv">
<dcterms:description>Maximum elastance right ventricle</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Prac">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_57">
<semsim:physicalPropertyOf rdf:resource="#entity_17" />
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00509" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Right atrial chamber pressure</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Eminrv">
<dcterms:description>Minimum elastance right ventricle</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Vx75">
<dcterms:description>P-V curve shaping parameter</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Vmax_sv">
<dcterms:description>Maximal volume of lumped systemic veins</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Fra">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_18">
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00299" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Flow across tricuspid valve</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Fsc">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_25">
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00299" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Systemic capillaries flow</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Fcorev">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_33">
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00299" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Epicardial veins flow</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Kr">
<dcterms:description>Pressure scaling constant for systemic arterial resistance</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Fcorcap">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_64">
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00299" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Coronary capillaries flow</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Pcorlac">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_17">
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00509" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Large coronary arteries chamber pressure</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.F_vaso">
<dcterms:description>Normalized discharge rate for vasomotor control</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Vmin_vc">
<dcterms:description>Mimimum volume of vena cava</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.SysArtVol">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_73">
<semsim:physicalPropertyOf rdf:resource="#entity_24" />
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00154" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Systemic arterial volume</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.KR">
<dcterms:description>Scaling factor for Vena cava resistance</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Vpcd">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_0">
<semsim:physicalPropertyOf>
<rdf:Description rdf:about="#entity_0">
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_9869" />
</rdf:Description>
</semsim:physicalPropertyOf>
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00154" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Total volume enclosed by pericardium</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.K1">
<dcterms:description>Scaling constant for unstressed and distended Vena cava pressure</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Ccorsv">
<dcterms:description>Compliance of small coronary veins</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Fcorao">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_2">
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00299" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Proximal epicardial arteries flow</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Faop">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_67">
<semsim:physicalPropertyOf>
<rdf:Description rdf:about="#process_1" dcterms:description="">
<semsim:hasMediatorParticipant>
<rdf:Description rdf:about="#mediator_1">
<semsim:hasPhysicalEntityReference>
<rdf:Description rdf:about="#entity_48">
<ro:part_of rdf:resource="#entity_34" />
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_14156" />
</rdf:Description>
</semsim:hasPhysicalEntityReference>
</rdf:Description>
</semsim:hasMediatorParticipant>
<semsim:hasSinkParticipant>
<rdf:Description rdf:about="#sink_1" semsim:hasMultiplier="1.0">
<semsim:hasPhysicalEntityReference rdf:resource="#entity_56" />
</rdf:Description>
</semsim:hasSinkParticipant>
<semsim:name>Blood flow through proximal aorta</semsim:name>
</rdf:Description>
</semsim:physicalPropertyOf>
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00299" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Proximal aorta flow</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Fvc">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_40">
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00299" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Vena cava flow</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.P_QRSwave">
<dcterms:description>Non-driving ECG curve</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Rav">
<dcterms:description>Aortic valve resistance</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Ppad">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_77">
<semsim:physicalPropertyOf>
<rdf:Description rdf:about="#entity_64">
<ro:part_of rdf:resource="#entity_36" />
<semsim:name>Wall of artery</semsim:name>
</rdf:Description>
</semsim:physicalPropertyOf>
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00509" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Distal pulmonary arterial transmural pressure</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#Heldt_Shim_2002" semsim:modelId="heldt_lpc_2002" semsim:modelName="heldt_lpc_2002">
<semsim:ModelerName>Max Neal</semsim:ModelerName>
<semsim:AnnotatorName>Chris Thompson</semsim:AnnotatorName>
<semsim:ModelDescription>Computational modeling of cardiovascular response to orthostatic stress</semsim:ModelDescription>
</rdf:Description>
<rdf:Description rdf:about="#lpc.perifl">
<dcterms:description>Pericardial fluid in pericardial cavity</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Caod">
<dcterms:description>Aortic distal compliance</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Ctpap">
<dcterms:description>Proximal pulmonary arterial compliance</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Fpv">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_5">
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00299" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Pulmonary veins flow</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Pcorcapc">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_27">
<semsim:physicalPropertyOf rdf:resource="#entity_22" />
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00509" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Coronary capillary chamber pressure</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Rps">
<dcterms:description>Pulmonary shunt resistance</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Psa">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_100">
<semsim:physicalPropertyOf rdf:resource="#entity_24" />
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00509" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Systemic arterial pressure</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Rpv">
<dcterms:description>Pulmonary veins resistance</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Tsv">
<dcterms:description>Discrete systolic interval for ventricles</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Vx8">
<dcterms:description>P-V curve shaping parameter</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Vaod">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_65">
<semsim:physicalPropertyOf rdf:resource="#entity_56" />
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00154" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Distal aorta volume</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Vla">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_71">
<semsim:physicalPropertyOf rdf:resource="#entity_29" />
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00154" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Fluid volume in the left atrium</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Csap">
<dcterms:description>Prox. systemic arteries compliance</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.SysVenVol">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_106">
<semsim:physicalPropertyOf rdf:resource="#entity_1" />
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00154" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Systemic venous volume</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Vcorlv">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_7">
<semsim:physicalPropertyOf>
<rdf:Description rdf:about="#entity_5">
<ro:part_of>
<rdf:Description rdf:about="#entity_6">
<semsim:name>Large coronary veins</semsim:name>
</rdf:Description>
</ro:part_of>
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_9670" />
</rdf:Description>
</semsim:physicalPropertyOf>
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00154" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Large coronary veins volume</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Rtaod">
<dcterms:description>Transmural distal aortic resistance</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Fcorsv">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_15">
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00299" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Small coronary veins flow</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Rpuv">
<dcterms:description>Pulmonary valve resistance</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.TsaK">
<dcterms:description>Scaler to set atrial systolic fraction of heart cycle</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Cpa">
<dcterms:description>Pulmonary arterioles compliance</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Paop">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_52">
<semsim:physicalPropertyOf rdf:resource="#entity_48" />
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00509" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Proximal aorta transmural pressure</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#lpc.Vlvr">
<dcterms:description>Unstressed left ventricle volume</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#Heldt_Shim_2002" semsim:modelName="Heldt_Shim_2002" semsim:unknown="Heldt_Shim_2002">
<ro:modelOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0004535" />
<ro:compartmentOf rdf:resource="http://purl.obolibrary.org/obo/FMA_9670" />
<ro:compartmentOf rdf:resource="http://purl.obolibrary.org/obo/FMA_7088" />
<ro:compartmentOf rdf:resource="http://purl.obolibrary.org/obo/FMA_7098" />
<ro:compartmentOf rdf:resource="http://purl.obolibrary.org/obo/FMA_7101" />
<ro:located_in rdf:resource="http://purl.obolibrary.org/obo/FMA_9670" />
<ro:located_in rdf:resource="http://purl.obolibrary.org/obo/FMA_7088" />
<ro:located_in rdf:resource="http://purl.obolibrary.org/obo/FMA_7098" />
<ro:located_in rdf:resource="http://purl.obolibrary.org/obo/FMA_7101" />
<ro:compartmentOf rdf:resource="http://purl.obolibrary.org/obo/FMA_84669" />
<ro:located_in rdf:resource="http://purl.obolibrary.org/obo/FMA_84669" />
</rdf:Description>
</rdf:RDF>
</model>
