Location: A Model of Cardiac Electrical Activity Incorporating Ionic Pumps and Concentration Changes, DiFrancesco, Noble, 1985 @ 0c3da9a59fd0 / model / DiFrancesco_Noble_1985.rdf

Author:

aram148 <42922407+aram148@users.noreply.github.com>

Date:

2020-05-11 14:07:48+12:00

Desc:

created html doc for sedml

Permanent Source URI:

https://models.cellml.org/workspace/59a/rawfile/0c3da9a59fd0cdf81188b1d931332d8015efe918/model/DiFrancesco_Noble_1985.rdf

<rdf:RDF
    xmlns:dcterms="http://purl.org/dc/terms/"
    xmlns:semsim="http://www.bhi.washington.edu/SemSim#"
    xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
    xmlns:bqmodel="http://biomodels.net/model-qualifiers/"
    xmlns:bqbiol="http://biomodels.net/biology-qualifiers/"
    xmlns:ro="http://www.obofoundry.org/ro/ro.owl#" > 
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#sodium_background_current.time">
    <dcterms:description>Time solution domain</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#transient_outward_current.Km_to">
    <dcterms:description>K half activation concentration for transient outward current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#entity_5">
    <bqbiol:isPartOf rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_6"/>
    <bqbiol:is rdf:resource="https://identifiers.org/chebi/CHEBI:29103"/>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#sodium_potassium_pump.time">
    <dcterms:description>Time solution domain</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#second_inward_current.Cai">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_10"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>Intracellular Ca concentration</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#source_20">
    <semsim:hasMultiplier>1.0</semsim:hasMultiplier>
    <semsim:hasPhysicalEntityReference rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_16"/>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#sink_22">
    <semsim:hasMultiplier>1.0</semsim:hasMultiplier>
    <semsim:hasPhysicalEntityReference rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_9"/>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#sodium_potassium_pump.K_mNa">
    <dcterms:description>NaK pump Na half activation concentration</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#intracellular_calcium_concentration.rCa">
    <dcterms:description>Number of Ca ions required to bind to activate release</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#Na_Ca_exchanger.d_NaCa">
    <dcterms:description>Denominator constant for i_NaCa</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#sink_10">
    <semsim:hasMultiplier>1.0</semsim:hasMultiplier>
    <semsim:hasPhysicalEntityReference rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_7"/>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#process_9">
    <semsim:hasMediatorParticipant rdf:resource="./DiFrancesco_Noble_1985.cellml#mediator_2"/>
    <semsim:hasSinkParticipant rdf:resource="./DiFrancesco_Noble_1985.cellml#sink_13"/>
    <semsim:hasSourceParticipant rdf:resource="./DiFrancesco_Noble_1985.cellml#source_13"/>
    <semsim:name>K transient outward channel current</semsim:name>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#hyperpolarising_activated_current.V">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_0"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>Cardiac myocyte membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#time_dependent_potassium_current_x_gate.beta_x">
    <dcterms:description>Delayed K rate coefficient</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#hyperpolarising_activated_current.E_Na">
    <dcterms:description>Sodium equilibrium potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#source_6">
    <semsim:hasMultiplier>1.0</semsim:hasMultiplier>
    <semsim:hasPhysicalEntityReference rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_10"/>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#intracellular_sodium_concentration.i_fNa">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#process_11"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>Na component of hyperpolarising activated current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#intracellular_sodium_concentration.i_Na_b">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#process_13"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>Sodium background current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#process_15">
    <semsim:hasSinkParticipant rdf:resource="./DiFrancesco_Noble_1985.cellml#sink_20"/>
    <semsim:hasSourceParticipant rdf:resource="./DiFrancesco_Noble_1985.cellml#source_20"/>
    <semsim:name>Ca release from sarcoplasmic reticulum into cytosol of cardiac myocyte</semsim:name>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#hyperpolarising_activated_current.g_f_K">
    <dcterms:description>K conductance of if channels</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#fast_sodium_current.E_mh">
    <dcterms:description>Reversal potential for sodium channel</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#entity_4">
    <bqbiol:isPartOf rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_3"/>
    <bqbiol:is rdf:resource="https://identifiers.org/chebi/CHEBI:29108"/>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#time_dependent_potassium_current_x_gate.alpha_x">
    <dcterms:description>Delayed K rate coefficient</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#second_inward_current.Nai">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_9"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>Intracellular Na concentration</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#source_21">
    <semsim:hasMultiplier>1.0</semsim:hasMultiplier>
    <semsim:hasPhysicalEntityReference rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_10"/>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#sink_11">
    <semsim:hasMultiplier>1.0</semsim:hasMultiplier>
    <semsim:hasPhysicalEntityReference rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_2"/>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#calcium_background_current.V">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_0"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>Cardiac myocyte membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#extracellular_potassium_concentration.Kc">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_5"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>Potassium concentration in the extracellular cleft</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#process_8">
    <semsim:hasSinkParticipant rdf:resource="./DiFrancesco_Noble_1985.cellml#sink_12"/>
    <semsim:hasSourceParticipant rdf:resource="./DiFrancesco_Noble_1985.cellml#source_12"/>
    <semsim:name>Delayed rectifier K channel current</semsim:name>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#second_inward_current.i_siNa">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#process_2"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>Sodium component of fast Ca current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#mediator_0">
    <semsim:hasPhysicalEntityReference rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_11"/>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#intracellular_calcium_concentration.F">
    <dcterms:description>Faraday Constant</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#time_dependent_potassium_current.i_K_max">
    <dcterms:description>Maximum outward potassium current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#sodium_potassium_pump.Nai">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_9"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>Intracellular Na concentration</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#membrane.i_pulse">
    <dcterms:description>Experimental stimulation current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#source_7">
    <semsim:hasMultiplier>1.0</semsim:hasMultiplier>
    <semsim:hasPhysicalEntityReference rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_2"/>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#process_14">
    <semsim:hasSinkParticipant rdf:resource="./DiFrancesco_Noble_1985.cellml#sink_19"/>
    <semsim:hasSourceParticipant rdf:resource="./DiFrancesco_Noble_1985.cellml#source_19"/>
    <semsim:name>Sarcoplasmic Ca transfer current</semsim:name>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#second_inward_current_d_gate.beta_d">
    <dcterms:description>Inactivation gating and rate coefficient for fast Ca current channel d gate</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#Na_Ca_exchanger.Nai">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_9"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>Intracellular Na concentration</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#transient_outward_current_s_gate.alpha_s">
    <dcterms:description>Rate coefficient for transient outward current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#process_7">
    <semsim:hasMediatorParticipant rdf:resource="./DiFrancesco_Noble_1985.cellml#mediator_1"/>
    <semsim:hasSinkParticipant rdf:resource="./DiFrancesco_Noble_1985.cellml#sink_11"/>
    <semsim:hasSinkParticipant rdf:resource="./DiFrancesco_Noble_1985.cellml#sink_10"/>
    <semsim:hasSourceParticipant rdf:resource="./DiFrancesco_Noble_1985.cellml#source_11"/>
    <semsim:hasSourceParticipant rdf:resource="./DiFrancesco_Noble_1985.cellml#source_10"/>
    <semsim:name>NaK exchange pump current</semsim:name>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#intracellular_calcium_concentration.i_Ca_b">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#process_12"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>Calcium background current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#hyperpolarising_activated_current.Ki">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>Potassium intracellular concentration</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#source_10">
    <semsim:hasMultiplier>1.0</semsim:hasMultiplier>
    <semsim:hasPhysicalEntityReference rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_5"/>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#sink_12">
    <semsim:hasMultiplier>1.0</semsim:hasMultiplier>
    <semsim:hasPhysicalEntityReference rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_2"/>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#entity_7">
    <bqbiol:isPartOf rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_8"/>
    <bqbiol:is rdf:resource="https://identifiers.org/chebi/CHEBI:29103"/>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#time_dependent_potassium_current.I_K">
    <dcterms:description>Fully activated value of delayed K current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#membrane.time">
    <dcterms:description>Time solution domain</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#hyperpolarising_activated_current_y_gate.alpha_y">
    <dcterms:description>Rate coefficient for hyperpolarizing-activated NaK current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#source_22">
    <semsim:hasMultiplier>1.0</semsim:hasMultiplier>
    <semsim:hasPhysicalEntityReference rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_2"/>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#Na_Ca_exchanger.Cai">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_10"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>Intracellular Ca concentration</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#mediator_1">
    <semsim:hasPhysicalEntityReference rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_12"/>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#second_inward_current_f_gate.alpha_f">
    <dcterms:description>Inactivation gating and rate coefficient for fast Ca current channel</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#second_inward_current.Kc">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_5"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>Potassium concentration in the extracellular cleft</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#second_inward_current_f2_gate.time">
    <dcterms:description>Time solution domain</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#membrane.i_p">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#process_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>NaK exchange pump current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#intracellular_calcium_concentration.tau_rel">
    <dcterms:description>Time constant for Ca release</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#source_8">
    <semsim:hasMultiplier>1.0</semsim:hasMultiplier>
    <semsim:hasPhysicalEntityReference rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_5"/>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#process_17">
    <semsim:hasSinkParticipant rdf:resource="./DiFrancesco_Noble_1985.cellml#sink_22"/>
    <semsim:hasSourceParticipant rdf:resource="./DiFrancesco_Noble_1985.cellml#source_22"/>
    <semsim:name>Fast sodium channel current across plasma membrane</semsim:name>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#transient_outward_current.Ki">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>Potassium intracellular concentration</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#extracellular_potassium_concentration.i_mK">
    <dcterms:description>Net membrane potassium flux</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#time_independent_potassium_current.Km_K1">
    <dcterms:description>K half-activation concentration for inward K rectifier</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#process_6">
    <semsim:hasSinkParticipant rdf:resource="./DiFrancesco_Noble_1985.cellml#sink_9"/>
    <semsim:hasSourceParticipant rdf:resource="./DiFrancesco_Noble_1985.cellml#source_9"/>
    <semsim:name>Time independent K channel current</semsim:name>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#fast_sodium_current.Nai">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_9"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>Intracellular Na concentration</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#second_inward_current_f2_gate.V">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_0"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>Cardiac myocyte membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#intracellular_sodium_concentration.radius">
    <dcterms:description>Radius of preparation</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#transient_outward_current_s_gate.s">
    <dcterms:description>Gating variable for transient outward current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#fast_sodium_current.g_Na">
    <dcterms:description>Conductance of  fast sodium current channels</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#sink_13">
    <semsim:hasMultiplier>1.0</semsim:hasMultiplier>
    <semsim:hasPhysicalEntityReference rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_5"/>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#membrane.i_NaCa">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#process_4"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>Na-Ca exchange current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#entity_6">
    <dcterms:description>Channel between two tightly packed cell.</dcterms:description>
    <semsim:name>Intercellular cleft</semsim:name>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#transient_outward_current_i_to">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#process_9"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>Transient outward current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#source_11">
    <semsim:hasMultiplier>1.0</semsim:hasMultiplier>
    <semsim:hasPhysicalEntityReference rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_9"/>
  </rdf:Description>
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  &lt;article&gt;&#xD;
    &lt;articleinfo&gt;&#xD;
      &lt;title&gt;Di Francesco-Noble Purkinje Fibre Model 1985&lt;/title&gt;&#xD;
      &lt;author&gt;&#xD;
        &lt;firstname&gt;Catherine&lt;/firstname&gt;&#xD;
        &lt;surname&gt;Lloyd&lt;/surname&gt;&#xD;
        &lt;affiliation&gt;&#xD;
          &lt;shortaffil&gt;Bioengineering Institute, University of Auckland&lt;/shortaffil&gt;&#xD;
        &lt;/affiliation&gt;&#xD;
      &lt;/author&gt;&#xD;
    &lt;/articleinfo&gt;&#xD;
    &lt;section id="sec_status"&gt;&#xD;
      &lt;title&gt;Model Status&lt;/title&gt;&#xD;
      &lt;para&gt;This model has been curated and unit-checked by Penny Noble of Oxford University and is known to run in PCEnv and COR and reproduce the results published in the paper it is based on.&lt;/para&gt;&#xD;
    &lt;/section&gt;&#xD;
    &lt;sect1 id="sec_structure"&gt;&#xD;
      &lt;title&gt;Model Structure&lt;/title&gt;&#xD;
      &lt;para&gt;During the years that followed the formulation of the McAllister-Noble-Tsien Purkinje fibre model in 1975 and the Beeler-Reuter mammalian ventricular model in 1977, many experiments were performed which provided a greater insight into the working of the ion channels in cardiac tissue.  D. Di Francesco and D. Noble (1985) constructed a new model of cardiac electrical activity which sought to incorporate much of this new data (see the figure below).&lt;/para&gt;&#xD;
      &lt;para&gt;The complete original paper reference is cited below:&lt;/para&gt;&#xD;
      &lt;para&gt;&#xD;
        A Model of the Cardiac Electrical Activity Incorporating Ionic Pumps and Concentration Changes - Simulations of Ionic Currents and Concentration Changes, Di Francesco, D. and Noble, D.&#xD;
        &lt;ulink url="http://www.pubs.royalsoc.ac.uk/proc_bio/proc_bio.html"&gt;&#xD;
          &lt;emphasis&gt;Phil. Trans. R. Soc. Lond.&lt;/emphasis&gt;&#xD;
        &lt;/ulink&gt;&#xD;
        , B307, 353-398.  (The&#xD;
        &lt;ulink url="http://links.jstor.org/sici?sici=0080-4622%2819850110%29307%3A1133%3C353%3AAMOCEA%3E2.0.CO%3B2-O"&gt;full text&lt;/ulink&gt;&#xD;
        of the article is available to members on the JSTOR website.)&#xD;
        &lt;ulink url="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;list_uids=2578676&amp;amp;dopt=Abstract"&gt;PubMed ID: 2578676&lt;/ulink&gt;&#xD;
      &lt;/para&gt;&#xD;
      &lt;informalfigure float="0" id="fig_cell_diagram"&gt;&#xD;
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          &lt;imageobject&gt;&#xD;
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              &lt;title&gt;cell diagram of the DFN model showing ionic currents, pumps and exchangers within the sarcolemma and the sarcoplasmic reticulum&lt;/title&gt;&#xD;
            &lt;/objectinfo&gt;&#xD;
            &lt;imagedata fileref="difrancesco_noble_1985.png" /&gt;&#xD;
          &lt;/imageobject&gt;&#xD;
        &lt;/mediaobject&gt;&#xD;
        &lt;caption&gt;A schematic diagram describing the current flows across the cell membrane that are captured in the DFN model.&lt;/caption&gt;&#xD;
      &lt;/informalfigure&gt;&#xD;
      &lt;informalfigure float="0" id="fig_cellml_rendering"&gt;&#xD;
        &lt;mediaobject&gt;&#xD;
          &lt;imageobject&gt;&#xD;
            &lt;objectinfo&gt;&#xD;
              &lt;title&gt;the cellml rendering of the DFN model&lt;/title&gt;&#xD;
            &lt;/objectinfo&gt;&#xD;
            &lt;imagedata fileref="cellml_rendering.gif" /&gt;&#xD;
          &lt;/imageobject&gt;&#xD;
        &lt;/mediaobject&gt;&#xD;
        &lt;caption&gt;&#xD;
          The network defined in the CellML description of the Di Francesco-Noble model. A key describing the significance of the shapes of the components and the colours of the connections between them is in the&#xD;
          &lt;ulink url="${HTML_EXMPL_GRAPHICAL_NOTATION}"&gt;notation guide&lt;/ulink&gt;&#xD;
          .  For simplicity, not all the variables are shown.&#xD;
        &lt;/caption&gt;&#xD;
      &lt;/informalfigure&gt;&#xD;
      &lt;para&gt;&#xD;
        The membrane physically contains the currents, exchangers and pumps, as indicated by the blue arrows in&#xD;
        &lt;xref linkend="fig_cellml_rendering" /&gt;&#xD;
        . The currents act independently and are not connected to each other. Several of the channels encapsulate&#xD;
        &lt;emphasis&gt;and&lt;/emphasis&gt;&#xD;
        contain further components which represent activation and inactivation gates. The addition of an encapsulation relationship informs modellers and processing software that the gates are important parts of the current model. It also prevents any other components that aren't also encapsulated by the parent component from connecting to its gates, effectively hiding them from the rest of the model.&#xD;
      &lt;/para&gt;&#xD;
      &lt;para&gt;The breakdown of the model into components and the definition of encapsulation and containment relationships between them is somewhat arbitrary. When considering how a model should be broken into components, modellers are encouraged to consider which parts of a model might be re-used and how the physiological elements of the system being modelled are naturally bounded. Containment relationships should be used to provide simple rendering information for processing software (ideally, this will correspond to the layout of the physical system), and encapsulation should be used to group sets of components into sub-models.&lt;/para&gt;&#xD;
    &lt;/sect1&gt;&#xD;
  &lt;/article&gt;&#xD;
&lt;/documentation&gt;</semsim:hasCellMLdocumentation>
  </rdf:Description>
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    <semsim:name>Ca background current across plasma membrane of cardiac myocyte</semsim:name>
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    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>Potassium concentration in the extracellular cleft</dcterms:description>
  </rdf:Description>
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    <dcterms:description>Potassium equilibrium potential</dcterms:description>
  </rdf:Description>
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    <dcterms:description>Calcium equilibrium potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#fast_sodium_current_m_gate.beta_m">
    <dcterms:description>Activation gate and rate coefficient</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#intracellular_sodium_concentration.Vi">
    <dcterms:description>Total intracellular volume</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#sink_21">
    <semsim:hasMultiplier>1.0</semsim:hasMultiplier>
    <semsim:hasPhysicalEntityReference rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_14"/>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#intracellular_calcium_concentration.K_mCa">
    <dcterms:description>Half activation concentration for Ca binding to release site</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#second_inward_current.time">
    <dcterms:description>Time solution domain</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#transient_outward_current.s">
    <dcterms:description>Gating variable for transient outward current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#transient_outward_current_s_gate.time">
    <dcterms:description>Time solution domain</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#intracellular_sodium_concentration.F">
    <dcterms:description>Faraday Constant</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#second_inward_current_f2_gate.alpha_f2">
    <dcterms:description>Intracellular Ca dependent inactivation of fast calcium current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#fast_sodium_current_h_gate.beta_h">
    <dcterms:description>Inactivation gate and rate coefficient</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#sink_2">
    <semsim:hasMultiplier>1.0</semsim:hasMultiplier>
    <semsim:hasPhysicalEntityReference rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_10"/>
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  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#extracellular_potassium_concentration.i_K">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#process_8"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>Delayed K current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#fast_sodium_current_m_gate.m">
    <dcterms:description>Activation gate and rate coefficient</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#membrane.F">
    <dcterms:description>Faraday Constant</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#source_16">
    <semsim:hasMultiplier>1.0</semsim:hasMultiplier>
    <semsim:hasPhysicalEntityReference rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_2"/>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#process_1">
    <semsim:hasSinkParticipant rdf:resource="./DiFrancesco_Noble_1985.cellml#sink_3"/>
    <semsim:hasSourceParticipant rdf:resource="./DiFrancesco_Noble_1985.cellml#source_3"/>
    <semsim:name>Secondary Ca channel inward current</semsim:name>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#intracellular_calcium_concentration.i_siCa">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#process_1"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>Calcium component of fast current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#intracellular_sodium_concentration.V_e_ratio">
    <dcterms:description>Fraction occupied by extracellular space</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#second_inward_current_f_gate.f">
    <dcterms:description>Gating variable for fast Ca current channel f gate</dcterms:description>
  </rdf:Description>
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    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>Sodium background current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#hyperpolarising_activated_current_y_gate.time">
    <dcterms:description>Time solution domain</dcterms:description>
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  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#hyperpolarising_activated_current.Kc">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_5"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>Potassium concentration in the extracellular cleft</dcterms:description>
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  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#extracellular_potassium_concentration.i_K1">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#process_6"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>Time independent K current</dcterms:description>
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  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#entity_17">
    <bqbiol:is rdf:resource="http://identifiers.org/fma/FMA_62387"/>
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  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#sink_18">
    <semsim:hasMultiplier>1.0</semsim:hasMultiplier>
    <semsim:hasPhysicalEntityReference rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_2"/>
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  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#transient_outward_current.Kc">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_5"/>
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    <dcterms:description>Potassium concentration in the extracellular cleft</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#intracellular_calcium_concentration.V_up">
    <dcterms:description>Volume of sarcoplasmic reticulum (s.r.) uptake store</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#calcium_background_current.Cao">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_4"/>
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    <dcterms:description>Extracellular calcium concentration</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#hyperpolarising_activated_current_y_gate.beta_y">
    <dcterms:description>Rate coefficient for hyperpolarizing-activated NaK current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#second_inward_current_f_gate.V">
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    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>Cardiac myocyte membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#sodium_background_current.g_Nab">
    <dcterms:description>Sodium background conductance</dcterms:description>
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  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#membrane.i_f">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#process_10"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>Hyperpolarizing-activated NaK current</dcterms:description>
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    <dcterms:description>Total TTX-insensitive inward current</dcterms:description>
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    <dcterms:description>Time- and voltage-dependence of the exchange between storage&#xD;
and release sites.</dcterms:description>
  </rdf:Description>
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    <dcterms:description>Time solution domain</dcterms:description>
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    <dcterms:description>Inactivation gate and rate coefficient</dcterms:description>
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    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#process_13"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
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  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#entity_16">
    <bqbiol:isPartOf rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_17"/>
    <bqbiol:is rdf:resource="https://identifiers.org/chebi/CHEBI:29108"/>
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  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#fast_sodium_current.i_Na">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#process_17"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>TTX sensittive fast Na current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#sink_19">
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  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#intracellular_calcium_concentration.i_tr">
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    <dcterms:description>Ca transferred into releasable form</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#second_inward_current.f2">
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  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#intracellular_calcium_concentration.time">
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  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#Na_Ca_exchanger.K_NaCa">
    <dcterms:description>scaling factor for i_NaCa</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#fast_sodium_current.h">
    <dcterms:description>Gating variable for h gate</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#sink_4">
    <semsim:hasMultiplier>1.0</semsim:hasMultiplier>
    <semsim:hasPhysicalEntityReference rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_9"/>
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  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#source_18">
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    <semsim:hasPhysicalEntityReference rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_9"/>
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  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#intracellular_sodium_concentration.i_Na">
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    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>TTX sensittive fast Na current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#source_0">
    <semsim:hasMultiplier>1.0</semsim:hasMultiplier>
    <semsim:hasPhysicalEntityReference rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_2"/>
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  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#second_inward_current.Cao">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_4"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>Extracellular calcium concentration</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#calcium_background_current.g_Cab">
    <dcterms:description>Calcium background conductance</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#calcium_background_current.i_Ca_b">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#process_12"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>Calcium background current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#entity_14">
    <bqbiol:isPartOf rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_15"/>
    <bqbiol:is rdf:resource="https://identifiers.org/chebi/CHEBI:29108"/>
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  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#sink_7">
    <semsim:hasMultiplier>1.0</semsim:hasMultiplier>
    <semsim:hasPhysicalEntityReference rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_4"/>
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  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#entity_15">
    <bqbiol:isPartOf rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_1"/>
    <semsim:name>Sarcoplasmic reticulum uptake store</semsim:name>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#intracellular_sodium_concentration.i_NaCa">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#process_4"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>Na-Ca exchange current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#time_independent_potassium_current.time">
    <dcterms:description>Time solution domain</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#time_dependent_potassium_current_x_gate.V">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_0"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>Cardiac myocyte membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#sodium_potassium_pump.Kc">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_5"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>Potassium concentration in the extracellular cleft</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#hyperpolarising_activated_current.Nai">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_9"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>Intracellular Na concentration</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#source_1">
    <semsim:hasMultiplier>1.0</semsim:hasMultiplier>
    <semsim:hasPhysicalEntityReference rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_4"/>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#extracellular_potassium_concentration.pf">
    <dcterms:description>Rate constant for K exchange between bulk and cleft space</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#hyperpolarising_activated_current_y_gate.y">
    <dcterms:description>Gating variable for Hyperpolarizing-activated NaK current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#time_independent_potassium_current.g_K1">
    <dcterms:description>Inward K rectifier conductance</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#source_19">
    <semsim:hasMultiplier>1.0</semsim:hasMultiplier>
    <semsim:hasPhysicalEntityReference rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_14"/>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#transient_outward_current.Cai">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_10"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>Intracellular Ca concentration</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#intracellular_potassium_concentration.time">
    <dcterms:description>Time solution domain</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#sodium_background_current.E_Na">
    <dcterms:description>Sodium equilibrium potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#Na_Ca_exchanger.E_Na">
    <dcterms:description>Sodium equilibrium potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#entity_13">
    <bqbiol:isPartOf rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_3"/>
    <bqbiol:is rdf:resource="https://identifiers.org/chebi/CHEBI:29103"/>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#second_inward_current_d_gate.d">
    <dcterms:description>Gating variable for fast Ca current channel d gate</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#sink_6">
    <semsim:hasMultiplier>1.0</semsim:hasMultiplier>
    <semsim:hasPhysicalEntityReference rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_9"/>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#second_inward_current.Nao">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_2"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>Extracellular sodium concentration</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#intracellular_potassium_concentration.i_mK">
    <dcterms:description>Net membrane potassium flux</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#time_dependent_potassium_current.time">
    <dcterms:description>Time solution domain</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#transient_outward_current.V">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_0"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>Cardiac myocyte membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#intracellular_calcium_concentration.beta_p">
    <dcterms:description>Rate coefficient of p</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#intracellular_calcium_concentration.V_rel">
    <dcterms:description>Volume of store of releasable calcium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#process_5">
    <semsim:hasSinkParticipant rdf:resource="./DiFrancesco_Noble_1985.cellml#sink_8"/>
    <semsim:hasSourceParticipant rdf:resource="./DiFrancesco_Noble_1985.cellml#source_8"/>
    <semsim:name>Hyperpolarizing activated K channel current</semsim:name>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#second_inward_current_d_gate.time">
    <dcterms:description>Time solution domain</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#intracellular_sodium_concentration.i_p">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#process_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>NaK exchange pump current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#fast_sodium_current_m_gate.alpha_m">
    <dcterms:description>Activation gate and rate coefficient</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#entity_9">
    <bqbiol:isPartOf rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_8"/>
    <bqbiol:is rdf:resource="https://identifiers.org/chebi/CHEBI:29101"/>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#fast_sodium_current_h_gate.V">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_0"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>Cardiac myocyte membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#extracellular_potassium_concentration.i_to">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#process_9"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>Transient outward current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#sink_14">
    <semsim:hasMultiplier>1.0</semsim:hasMultiplier>
    <semsim:hasPhysicalEntityReference rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_7"/>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#calcium_background_current.time">
    <dcterms:description>Time solution domain</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#Na_Ca_exchanger.time">
    <dcterms:description>Time solution domain</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#entity_12">
    <bqbiol:isPartOf rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_0"/>
    <bqbiol:is rdf:resource="http://purl.obolibrary.org/obo/PR_P50993"/>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#fast_sodium_current.time">
    <dcterms:description>Time solution domain</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#environment_time">
    <dcterms:description>Time solution domain</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#transient_outward_current_s_gate.beta_s">
    <dcterms:description>Rate coefficient for transient outward current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#time_independent_potassium_current.V">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_0"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>Cardiac myocyte membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#intracellular_sodium_concentration.n_NaCa">
    <dcterms:description>Stoichiometry of Na-Ca exchange</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#sink_9">
    <semsim:hasMultiplier>1.0</semsim:hasMultiplier>
    <semsim:hasPhysicalEntityReference rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_5"/>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#time_independent_potassium_current_i_K1">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#process_6"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>Time independent K current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#mediator_3">
    <semsim:hasPhysicalEntityReference rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_0"/>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#extracellular_potassium_concentration.Ve">
    <dcterms:description>Total extracellular volume</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#time_dependent_potassium_current_x_gate.time">
    <dcterms:description>Time solution domain</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#fast_sodium_current.m">
    <dcterms:description>Activation gate and rate coefficient</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#Na_Ca_exchanger.gamma">
    <dcterms:description>Position of energy barrier controlling voltage-dependence of i_NaCa</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#extracellular_potassium_concentration.F">
    <dcterms:description>Faraday Constant</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#membrane.R">
    <dcterms:description>Boltzmann constant</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#hyperpolarising_activated_current.Km_f">
    <dcterms:description>Ionic half-activation concentration for hyperpolarising current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#process_4">
    <semsim:hasMediatorParticipant rdf:resource="./DiFrancesco_Noble_1985.cellml#mediator_0"/>
    <semsim:hasSinkParticipant rdf:resource="./DiFrancesco_Noble_1985.cellml#sink_7"/>
    <semsim:hasSinkParticipant rdf:resource="./DiFrancesco_Noble_1985.cellml#sink_6"/>
    <semsim:hasSourceParticipant rdf:resource="./DiFrancesco_Noble_1985.cellml#source_7"/>
    <semsim:hasSourceParticipant rdf:resource="./DiFrancesco_Noble_1985.cellml#source_6"/>
    <semsim:name>NaCa exchange pump current across plasma membrane</semsim:name>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#extracellular_potassium_concentration.time">
    <dcterms:description>Time solution domain</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#transient_outward_current.Km_Ca">
    <dcterms:description>Ca half activation concentration for transient outward current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#second_inward_current_d_gate.V">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_0"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>Cardiac myocyte membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#entity_8">
    <bqbiol:isPartOf rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_1"/>
    <bqbiol:is rdf:resource="http://identifiers.org/fma/FMA_66836"/>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#entity_11">
    <bqbiol:isPartOf rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_0"/>
    <bqbiol:is rdf:resource="http://purl.obolibrary.org/obo/PR_P48768"/>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#intracellular_potassium_concentration.Ki">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>Potassium intracellular concentration</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#membrane.C">
    <dcterms:description>Membrane capacitance</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#sink_8">
    <semsim:hasMultiplier>1.0</semsim:hasMultiplier>
    <semsim:hasPhysicalEntityReference rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_7"/>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#intracellular_calcium_concentration.i_up">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#process_16"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>Ca uptake into s.r. expressed as a current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#sink_15">
    <semsim:hasMultiplier>1.0</semsim:hasMultiplier>
    <semsim:hasPhysicalEntityReference rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_9"/>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#time_dependent_potassium_current_x_gate.x">
    <dcterms:description>Delayed K current gating variable</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#intracellular_calcium_concentration.i_rel">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#process_15"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>Ca release from junctional sarcoplasmic reticulum into cytosol</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#mediator_4">
    <semsim:hasPhysicalEntityReference rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_0"/>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#transient_outward_current.g_to">
    <dcterms:description>Conductance for transient outward K rectification</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#Na_Ca_exchanger.V">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_0"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>Cardiac myocyte membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#time_dependent_potassium_current.V">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_0"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>Cardiac myocyte membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#intracellular_calcium_concentration.n_NaCa">
    <dcterms:description>Stoichiometry of Na-Ca exchange</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#intracellular_calcium_concentration.V">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_0"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>Cardiac myocyte membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#intracellular_calcium_concentration.Ca_up">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_14"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>Ca concentration in s.r. uptake store</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#process_3">
    <semsim:hasSinkParticipant rdf:resource="./DiFrancesco_Noble_1985.cellml#sink_5"/>
    <semsim:hasSourceParticipant rdf:resource="./DiFrancesco_Noble_1985.cellml#source_5"/>
    <semsim:name>Secondary K channel inward current</semsim:name>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#intracellular_sodium_concentration.V_Cell">
    <dcterms:description>Total intracellular volume</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#entity_10">
    <bqbiol:isPartOf rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_8"/>
    <bqbiol:is rdf:resource="https://identifiers.org/chebi/CHEBI:29108"/>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#sodium_potassium_pump.K_mK">
    <dcterms:description>NaK pump K half activation concentration</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#extracellular_potassium_concentration.Kb">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_13"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>Bulk extracellular potassium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#fast_sodium_current_m_gate.V">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_0"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>Cardiac myocyte membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#membrane.i_K">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#process_8"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>Delayed K current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#second_inward_current.i_siK">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#process_3"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>Potassium component of fast Ca current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#membrane.i_K1">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#process_6"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>Time independent K current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#sink_16">
    <semsim:hasMultiplier>1.0</semsim:hasMultiplier>
    <semsim:hasPhysicalEntityReference rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_9"/>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#fast_sodium_current.Kc">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_5"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>Potassium concentration in the extracellular cleft</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#fast_sodium_current.Nao">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_2"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>Extracellular sodium concentration</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#intracellular_calcium_concentration.tau_rep">
    <dcterms:description>Time constant for repriming release store</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#hyperpolarising_activated_current.Nao">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_2"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>Extracellular sodium concentration</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#calcium_background_current.Cai">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_10"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>Intracellular Ca concentration</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#membrane.T">
    <dcterms:description>Temperature</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#membrane_V">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_0"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>Cardiac myocyte membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#second_inward_current_f2_gate.Cai">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_10"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>Intracellular Ca concentration</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#time_dependent_potassium_current.Kc">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_5"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>Potassium concentration in the extracellular cleft</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#time_dependent_potassium_current.x">
    <dcterms:description>Delayed K current gating variable</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#process_2">
    <semsim:hasSinkParticipant rdf:resource="./DiFrancesco_Noble_1985.cellml#sink_4"/>
    <semsim:hasSourceParticipant rdf:resource="./DiFrancesco_Noble_1985.cellml#source_4"/>
    <semsim:name>Secondary Na channel inward current</semsim:name>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#hyperpolarising_activated_current.g_f_Na">
    <dcterms:description>Na conductance of if channels</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#fast_sodium_current_m_gate.time">
    <dcterms:description>Time solution domain</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#second_inward_current.i_siCa">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#process_1"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>Calcium component of fast current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#second_inward_current.Ki">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>Potassium intracellular concentration</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#time_independent_potassium_current.E_K">
    <dcterms:description>Potassium equilibrium potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#intracellular_calcium_concentration.Ca_rel">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_16"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>Ca concentrations in s.r. release store</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#sink_17">
    <semsim:hasMultiplier>1.0</semsim:hasMultiplier>
    <semsim:hasPhysicalEntityReference rdf:resource="./DiFrancesco_Noble_1985.cellml#entity_4"/>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#second_inward_current_f_gate.beta_f">
    <dcterms:description>Inactivation gating and rate coefficient for fast Ca current channel</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#fast_sodium_current_h_gate.h">
    <dcterms:description>Gating variable for h gate</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./DiFrancesco_Noble_1985.cellml#hyperpolarising_activated_current_i_f">
    <bqbiol:isPropertyOf rdf:resource="./DiFrancesco_Noble_1985.cellml#process_10"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>Hyperpolarizing-activated NaK current</dcterms:description>
  </rdf:Description>
</rdf:RDF>