- Author:
- WeiweiAi <wai484@aucklanduni.ac.nz>
- Date:
- 2021-04-27 14:28:37+12:00
- Desc:
- Change .xml to cellml;
Add temperature_factor.cellml and corresponding modification to include tempeature in the model;
Add clamped_current.cellml, voltage_clamp_protocol.cellml and voltage_clamp_experiment.cellml to simulate membrance current during voltage clamp ( there is an issue at -10 mV but works fine at other voltage conditions);
Add propagated_AP.cellml and AP_propagation_experiment.cellml to simulate propagated action potential (issue: the AP doesn't fall);
Add data derived from the figures in the original paper using Engauge Digitizer;
- Permanent Source URI:
- https://models.cellml.org/workspace/64f/rawfile/01b5e3d2e6dd9987f71682214516c78e4dd76916/components/Ileak.cellml
<?xml version='1.0' encoding='UTF-8'?>
<model name="Ileak" xmlns="http://www.cellml.org/cellml/1.1#" xmlns:cellml="http://www.cellml.org/cellml/1.1#" xmlns:xlink="http://www.w3.org/1999/xlink">
<import xlink:href="units.cellml">
<units name="mV" units_ref="mV"/>
<units name="uA_per_cmsq" units_ref="uA_per_cmsq"/>
<units name="mS_per_cmsq" units_ref="mS_per_cmsq"/>
</import>
<component name="Ileak">
<variable name="Ileak" private_interface="out" public_interface="out" units="uA_per_cmsq"/>
<variable name="V" private_interface="out" public_interface="in" units="mV"/>
<variable name="Vleak" private_interface="out" public_interface="in" units="mV"/>
<variable name="gleak_max" private_interface="out" public_interface="in" units="mS_per_cmsq"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply id="Ileak_calculation">
<eq/>
<ci>Ileak</ci>
<apply>
<times/>
<ci>gleak_max</ci>
<apply>
<minus/>
<ci>V</ci>
<ci>Vleak</ci>
</apply>
</apply>
</apply>
</math>
</component>
</model>
