Location: Hodgkin & Huxley (1952) model @ 01b5e3d2e6dd / components / temperature_factor.cellml

Author:
WeiweiAi <wai484@aucklanduni.ac.nz>
Date:
2021-04-27 14:28:37+12:00
Desc:
Change .xml to cellml; Add temperature_factor.cellml and corresponding modification to include tempeature in the model; Add clamped_current.cellml, voltage_clamp_protocol.cellml and voltage_clamp_experiment.cellml to simulate membrance current during voltage clamp ( there is an issue at -10 mV but works fine at other voltage conditions); Add propagated_AP.cellml and AP_propagation_experiment.cellml to simulate propagated action potential (issue: the AP doesn't fall); Add data derived from the figures in the original paper using Engauge Digitizer;
Permanent Source URI:
https://models.cellml.org/workspace/64f/rawfile/01b5e3d2e6dd9987f71682214516c78e4dd76916/components/temperature_factor.cellml
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<?xml version='1.0' encoding='UTF-8'?>
<model name="temperature_factor" xmlns="http://www.cellml.org/cellml/1.1#" xmlns:cellml="http://www.cellml.org/cellml/1.1#">
    <!-- calculate temperature factor-->
    <component name="temperature_factor">
        <variable name="phi" public_interface="out" units="dimensionless"/>
        <variable name="T" public_interface="in" units="celsius"/>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
                <eq/>
                <ci>phi</ci>
                <apply>
                    <power/>
                    <cn cellml:units="dimensionless">3</cn>
                    <apply>
                        <divide/>
                        <apply>
                            <minus/>
                            <ci>T</ci>
                            <cn cellml:units="celsius">6.3</cn>
                        </apply>
                        <cn cellml:units="celsius">10</cn>
                    </apply>
                </apply>
            </apply>
        </math>
    </component>
</model>