Location: Hodgkin & Huxley (1952) model @ 01b5e3d2e6dd / index.html
- Author:
- WeiweiAi <wai484@aucklanduni.ac.nz>
- Date:
- 2021-04-27 14:28:37+12:00
- Desc:
- Change .xml to cellml; Add temperature_factor.cellml and corresponding modification to include tempeature in the model; Add clamped_current.cellml, voltage_clamp_protocol.cellml and voltage_clamp_experiment.cellml to simulate membrance current during voltage clamp ( there is an issue at -10 mV but works fine at other voltage conditions); Add propagated_AP.cellml and AP_propagation_experiment.cellml to simulate propagated action potential (issue: the AP doesn't fall); Add data derived from the figures in the original paper using Engauge Digitizer;
- Permanent Source URI:
- https://models.cellml.org/workspace/64f/rawfile/01b5e3d2e6dd9987f71682214516c78e4dd76916/index.html
This workspace holds an encoding of the Hodgkin & Huxley (1952) model, designed as useful example to use for explaining the basics of using CellML. A more comprehensive encoding of the Hodgkin & Huxley model is also available.
Direct links to some of the useful documents in this workspace:
- The complete Hodgkin & Huxley mathematical model:
components/stimulated.xml; the base model to be instantiated into specific simulation experiments which set the stimulus protocol. - The complete set of default parameter values and initial conditions from the HH paper:
components/default-variable-values.xml - The HH model configured and parameterised with an applied periodic stimulus current:
experiments/periodic-stimulus.xml - A SED-ML description of a simulation experiment for the periodic stimulus experiment:
sed-ml/periodic-stimulus.xml; can be used in the SED-ML Web Tools to produce the results shown in the tutorial.