- Author:
- WeiweiAi <wai484@aucklanduni.ac.nz>
- Date:
- 2022-03-31 10:48:40+13:00
- Desc:
- Add open channel IV of HH models; Add simulation and plot python scripts
- Permanent Source URI:
- https://models.cellml.org/workspace/64f/rawfile/ab2962b8796666ad9938a2577611c954f006b5fd/components/INa-gating-rates.cellml
<?xml version='1.0' encoding='UTF-8'?>
<model name="INa_gating_rates" xmlns="http://www.cellml.org/cellml/1.1#" xmlns:cellml="http://www.cellml.org/cellml/1.1#" xmlns:xlink="http://www.w3.org/1999/xlink">
<import xlink:href="../cellLib/Components/units.cellml">
<units name="ms" units_ref="ms"/>
<units name="mV" units_ref="mV"/>
<units name="per_ms" units_ref="per_ms"/>
<units name="per_ms_mV" units_ref="per_ms_mV"/>
</import>
<component name="alpha_m">
<variable name="alpha" private_interface="out" public_interface="out" units="per_ms"/>
<variable name="V" private_interface="out" public_interface="in" units="mV"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply id="alpha_m_calculation">
<eq/>
<ci>alpha</ci>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="per_ms_mV">0.1</cn>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="mV">25.0</cn>
</apply>
</apply>
<apply>
<minus/>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="mV">25.0</cn>
</apply>
<cn cellml:units="mV">10.0</cn>
</apply>
</apply>
<cn cellml:units="dimensionless">1.0</cn>
</apply>
</apply>
</apply>
</math>
</component>
<component name="beta_m">
<variable name="beta" private_interface="out" public_interface="out" units="per_ms"/>
<variable name="V" private_interface="out" public_interface="in" units="mV"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply id="beta_m_calculation">
<eq/>
<ci>beta</ci>
<apply>
<times/>
<cn cellml:units="per_ms">4.0</cn>
<apply>
<exp/>
<apply>
<divide/>
<ci>V</ci>
<cn cellml:units="mV">18.0</cn>
</apply>
</apply>
</apply>
</apply>
</math>
</component>
<component name="alpha_h">
<variable name="alpha" private_interface="out" public_interface="out" units="per_ms"/>
<variable name="V" private_interface="out" public_interface="in" units="mV"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply id="alpha_h_calculation">
<eq/>
<ci>alpha</ci>
<apply>
<times/>
<cn cellml:units="per_ms">0.07</cn>
<apply>
<exp/>
<apply>
<divide/>
<ci>V</ci>
<cn cellml:units="mV">20.0</cn>
</apply>
</apply>
</apply>
</apply>
</math>
</component>
<component name="beta_h">
<variable name="beta" private_interface="out" public_interface="out" units="per_ms"/>
<variable name="V" private_interface="out" public_interface="in" units="mV"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply id="beta_h_calculation">
<eq/>
<ci>beta</ci>
<apply>
<divide/>
<cn cellml:units="per_ms">1.0</cn>
<apply>
<plus/>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="mV">30.0</cn>
</apply>
<cn cellml:units="mV">10.0</cn>
</apply>
</apply>
<cn cellml:units="dimensionless">1.0</cn>
</apply>
</apply>
</apply>
</math>
</component>
</model>
