Location: Model of Human Jejunal Smooth Muscle Cell Electrophysiology @ 4de8d2594e8e / Components / ICaL_channel_states_off.cellml
- Author:
- WeiweiAi <wai484@aucklanduni.ac.nz>
- Date:
- 2021-06-09 17:59:55+12:00
- Desc:
- Update figure titles and documentation;
- Permanent Source URI:
- https://models.cellml.org/workspace/692/rawfile/4de8d2594e8e71c62b4f118f49fde8a277df70d7/Components/ICaL_channel_states_off.cellml
<?xml version='1.0' encoding='UTF-8'?>
<model name="ICaL_channel_states" xmlns="http://www.cellml.org/cellml/1.1#" xmlns:cellml="http://www.cellml.org/cellml/1.1#" xmlns:xlink="http://www.w3.org/1999/xlink">
<import xlink:href="units.cellml">
<units name="mM" units_ref="mM"/>
<units name="ms" units_ref="ms"/>
<units name="mV" units_ref="mV"/>
<units name="per_ms" units_ref="per_ms"/>
</import>
<import xlink:href="temperature_factor.cellml">
<component component_ref="temperature_factor" name="temperature_factor"/>
</import>
<component name="ICaL_channel_states">
<variable name="C0_init" public_interface="in" units="dimensionless"/>
<variable name="C1_init" public_interface="in" units="dimensionless"/>
<variable name="C2_init" public_interface="in" units="dimensionless"/>
<variable name="C3_init" public_interface="in" units="dimensionless"/>
<variable name="C0Ca_init" public_interface="in" units="dimensionless"/>
<variable name="C1Ca_init" public_interface="in" units="dimensionless"/>
<variable name="C2Ca_init" public_interface="in" units="dimensionless"/>
<variable name="C3Ca_init" public_interface="in" units="dimensionless"/>
<variable name="ICa_init" public_interface="in" units="dimensionless"/>
<variable name="IVs_init" public_interface="in" units="dimensionless"/>
<variable name="IVf_init" public_interface="in" units="dimensionless"/>
<variable name="IVfCa_init" public_interface="in" units="dimensionless"/>
<variable name="IVsCa_init" public_interface="in" units="dimensionless"/>
<variable name="O_CaL_init" public_interface="in" units="dimensionless"/>
<variable name="time" public_interface="in" units="ms"/>
<variable name="V" public_interface="in" units="mV"/>
<variable name="Cai" public_interface="in" units="mM"/>
<variable name="Q10Ca" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="T" private_interface="out" public_interface="in" units="kelvin"/>
<variable name="T0" private_interface="out" public_interface="in" units="kelvin"/>
<variable initial_value="C0_init" name="C0" units="dimensionless"/>
<variable initial_value="C1_init" name="C1" units="dimensionless"/>
<variable initial_value="C2_init" name="C2" units="dimensionless"/>
<variable initial_value="C3_init" name="C3" units="dimensionless"/>
<variable initial_value="C0Ca_init" name="C0Ca" units="dimensionless"/>
<variable initial_value="C1Ca_init" name="C1Ca" units="dimensionless"/>
<variable initial_value="C2Ca_init" name="C2Ca" units="dimensionless"/>
<variable initial_value="C3Ca_init" name="C3Ca" units="dimensionless"/>
<variable initial_value="ICa_init" name="ICa" units="dimensionless"/>
<variable initial_value="IVs_init" name="IVs" units="dimensionless"/>
<variable initial_value="IVf_init" name="IVf" units="dimensionless"/>
<variable initial_value="IVfCa_init" name="IVfCa" units="dimensionless"/>
<variable initial_value="IVfCa_init" name="IVsCa" units="dimensionless"/>
<variable name="alpha" units="per_ms"/>
<variable name="beta" units="per_ms"/>
<variable name="alpha_0" units="per_ms"/>
<variable name="alpha_1" units="per_ms"/>
<variable name="alpha_2" units="per_ms"/>
<variable name="alpha_3" units="per_ms"/>
<variable name="beta_0" units="per_ms"/>
<variable name="beta_1" units="per_ms"/>
<variable name="beta_2" units="per_ms"/>
<variable name="beta_3" units="per_ms"/>
<variable name="delta" units="per_ms"/>
<variable name="theta" units="per_ms"/>
<variable name="phi_s" units="per_ms"/>
<variable name="phi_f" units="per_ms"/>
<variable name="omega_s" units="per_ms"/>
<variable name="omega_f" units="per_ms"/>
<variable name="omega_fs" units="per_ms"/>
<variable name="omega_sf" units="per_ms"/>
<variable name="psi_s" units="per_ms"/>
<variable name="psi_f" units="per_ms"/>
<variable name="xi_s" units="per_ms"/>
<variable name="xi_f" units="per_ms"/>
<variable name="norm" units="dimensionless"/>
<variable initial_value="O_CaL_init" name="O_CaL" public_interface="out" units="dimensionless"/>
<variable name="phi" private_interface="in" units="dimensionless"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>alpha</ci>
<apply>
<times/>
<ci>phi</ci>
<cn cellml:units="per_ms">0.731</cn>
<apply>
<exp/>
<apply>
<divide/>
<ci>V</ci>
<cn cellml:units="mV">30</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>beta</ci>
<apply>
<times/>
<ci>phi</ci>
<cn cellml:units="per_ms">0.2149</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<ci>V</ci>
</apply>
<cn cellml:units="mV">40</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>alpha_0</ci>
<apply>
<times/>
<cn cellml:units="dimensionless">4</cn>
<ci>alpha</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>alpha_1</ci>
<apply>
<times/>
<cn cellml:units="dimensionless">3</cn>
<ci>alpha</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>alpha_2</ci>
<apply>
<times/>
<cn cellml:units="dimensionless">2</cn>
<ci>alpha</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>alpha_3</ci>
<apply>
<times/>
<cn cellml:units="dimensionless">1</cn>
<ci>alpha</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>beta_0</ci>
<apply>
<times/>
<cn cellml:units="dimensionless">1</cn>
<ci>beta</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>beta_1</ci>
<apply>
<times/>
<cn cellml:units="dimensionless">2</cn>
<ci>beta</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>beta_2</ci>
<apply>
<times/>
<cn cellml:units="dimensionless">3</cn>
<ci>beta</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>beta_3</ci>
<apply>
<times/>
<cn cellml:units="dimensionless">4</cn>
<ci>beta</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>phi_f</ci>
<apply>
<times/>
<ci>phi</ci>
<cn cellml:units="per_ms">0.4742</cn>
<apply>
<exp/>
<apply>
<divide/>
<ci>V</ci>
<cn cellml:units="mV">10</cn>
</apply>
</apply>
</apply>
</apply>
<!-- phi_s = phi*0.05956{per_ms}*exp(-V/40{mV});-->
<apply>
<eq/>
<ci>phi_s</ci>
<apply>
<times/>
<ci>phi</ci>
<cn cellml:units="per_ms">0.005956</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<ci>V</ci>
</apply>
<cn cellml:units="mV">40</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>xi_f</ci>
<apply>
<times/>
<ci>phi</ci>
<cn cellml:units="per_ms">0.01407</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<ci>V</ci>
</apply>
<cn cellml:units="mV">300</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>xi_s</ci>
<apply>
<times/>
<ci>phi</ci>
<cn cellml:units="per_ms">0.01213</cn>
<apply>
<exp/>
<apply>
<divide/>
<ci>V</ci>
<cn cellml:units="mV">500</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>psi_f</ci>
<apply>
<times/>
<ci>phi</ci>
<cn cellml:units="per_ms">0.02197</cn>
<apply>
<exp/>
<apply>
<divide/>
<ci>V</ci>
<cn cellml:units="mV">500</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>psi_s</ci>
<apply>
<times/>
<ci>phi</ci>
<cn cellml:units="per_ms">0.00232</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<ci>V</ci>
</apply>
<cn cellml:units="mV">280</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>omega_f</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>beta_3</ci>
<ci>xi_f</ci>
<ci>phi_f</ci>
</apply>
<apply>
<times/>
<ci>alpha_3</ci>
<ci>psi_f</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>omega_s</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>beta_3</ci>
<ci>xi_s</ci>
<ci>phi_s</ci>
</apply>
<apply>
<times/>
<ci>alpha_3</ci>
<ci>psi_s</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>omega_sf</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>xi_s</ci>
<ci>psi_f</ci>
</apply>
<ci>xi_f</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>omega_fs</ci>
<ci>psi_s</ci>
</apply>
<apply>
<eq/>
<ci>delta</ci>
<cn cellml:units="per_ms">0</cn>
</apply>
<apply>
<eq/>
<ci>theta</ci>
<cn cellml:units="per_ms">0</cn>
</apply>
<apply>
<eq/>
<ci>norm</ci>
<apply>
<plus/>
<ci>C3</ci>
<ci>C2</ci>
<ci>C1</ci>
<ci>C0</ci>
<ci>C3Ca</ci>
<ci>C2Ca</ci>
<ci>C1Ca</ci>
<ci>C0Ca</ci>
<ci>O_CaL</ci>
<ci>ICa</ci>
<ci>IVs</ci>
<ci>IVf</ci>
<ci>IVsCa</ci>
<ci>IVfCa</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>C3</ci>
</apply>
<apply>
<plus/>
<apply>
<minus/>
<apply>
<divide/>
<apply>
<times/>
<ci>alpha_2</ci>
<ci>C2</ci>
</apply>
<ci>norm</ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<apply>
<plus/>
<ci>alpha_3</ci>
<ci>beta_2</ci>
<ci>phi_s</ci>
<ci>phi_f</ci>
<ci>theta</ci>
</apply>
<ci>C3</ci>
</apply>
<ci>norm</ci>
</apply>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci>beta_3</ci>
<ci>O_CaL</ci>
</apply>
<ci>norm</ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci>omega_f</ci>
<ci>IVf</ci>
</apply>
<ci>norm</ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci>omega_s</ci>
<ci>IVs</ci>
</apply>
<ci>norm</ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci>delta</ci>
<ci>C3Ca</ci>
</apply>
<ci>norm</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>C2</ci>
</apply>
<apply>
<plus/>
<apply>
<minus/>
<apply>
<divide/>
<apply>
<times/>
<ci>alpha_1</ci>
<ci>C1</ci>
</apply>
<ci>norm</ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<apply>
<plus/>
<ci>alpha_2</ci>
<ci>beta_1</ci>
<ci>theta</ci>
</apply>
<ci>C2</ci>
</apply>
<ci>norm</ci>
</apply>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci>beta_2</ci>
<ci>C3</ci>
</apply>
<ci>norm</ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci>delta</ci>
<ci>C2Ca</ci>
</apply>
<ci>norm</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>C1</ci>
</apply>
<apply>
<plus/>
<apply>
<minus/>
<apply>
<divide/>
<apply>
<times/>
<ci>alpha_0</ci>
<ci>C0</ci>
</apply>
<ci>norm</ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<apply>
<plus/>
<ci>alpha_1</ci>
<ci>beta_0</ci>
<ci>theta</ci>
</apply>
<ci>C1</ci>
</apply>
<ci>norm</ci>
</apply>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci>beta_1</ci>
<ci>C2</ci>
</apply>
<ci>norm</ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci>delta</ci>
<ci>C1Ca</ci>
</apply>
<ci>norm</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>C0</ci>
</apply>
<apply>
<plus/>
<apply>
<divide/>
<apply>
<times/>
<apply>
<minus/>
<apply>
<plus/>
<ci>alpha_0</ci>
<ci>theta</ci>
</apply>
</apply>
<ci>C0</ci>
</apply>
<ci>norm</ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci>beta_0</ci>
<ci>C1</ci>
</apply>
<ci>norm</ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci>delta</ci>
<ci>C0Ca</ci>
</apply>
<ci>norm</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>C3Ca</ci>
</apply>
<apply>
<plus/>
<apply>
<minus/>
<apply>
<plus/>
<apply>
<divide/>
<apply>
<times/>
<ci>theta</ci>
<ci>C3</ci>
</apply>
<ci>norm</ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci>alpha_2</ci>
<ci>C2Ca</ci>
</apply>
<ci>norm</ci>
</apply>
</apply>
<apply>
<divide/>
<apply>
<times/>
<apply>
<plus/>
<ci>alpha_3</ci>
<ci>beta_2</ci>
<ci>phi_f</ci>
<ci>phi_s</ci>
<ci>delta</ci>
</apply>
<ci>C3Ca</ci>
</apply>
<ci>norm</ci>
</apply>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci>beta_3</ci>
<ci>ICa</ci>
</apply>
<ci>norm</ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci>omega_f</ci>
<ci>IVfCa</ci>
</apply>
<ci>norm</ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci>omega_s</ci>
<ci>IVsCa</ci>
</apply>
<ci>norm</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>C2Ca</ci>
</apply>
<apply>
<plus/>
<apply>
<minus/>
<apply>
<plus/>
<apply>
<divide/>
<apply>
<times/>
<ci>theta</ci>
<ci>C2</ci>
</apply>
<ci>norm</ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci>alpha_1</ci>
<ci>C1Ca</ci>
</apply>
<ci>norm</ci>
</apply>
</apply>
<apply>
<divide/>
<apply>
<times/>
<apply>
<plus/>
<ci>alpha_2</ci>
<ci>beta_1</ci>
<ci>delta</ci>
</apply>
<ci>C2Ca</ci>
</apply>
<ci>norm</ci>
</apply>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci>beta_2</ci>
<ci>C3Ca</ci>
</apply>
<ci>norm</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>C1Ca</ci>
</apply>
<apply>
<plus/>
<apply>
<minus/>
<apply>
<plus/>
<apply>
<divide/>
<apply>
<times/>
<ci>theta</ci>
<ci>C1</ci>
</apply>
<ci>norm</ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci>alpha_0</ci>
<ci>C0Ca</ci>
</apply>
<ci>norm</ci>
</apply>
</apply>
<apply>
<divide/>
<apply>
<times/>
<apply>
<plus/>
<ci>alpha_1</ci>
<ci>beta_0</ci>
<ci>delta</ci>
</apply>
<ci>C1Ca</ci>
</apply>
<ci>norm</ci>
</apply>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci>beta_1</ci>
<ci>C2Ca</ci>
</apply>
<ci>norm</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>C0Ca</ci>
</apply>
<apply>
<plus/>
<apply>
<minus/>
<apply>
<divide/>
<apply>
<times/>
<ci>theta</ci>
<ci>C0</ci>
</apply>
<ci>norm</ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<apply>
<plus/>
<ci>alpha_0</ci>
<ci>delta</ci>
</apply>
<ci>C0Ca</ci>
</apply>
<ci>norm</ci>
</apply>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci>beta_0</ci>
<ci>C1Ca</ci>
</apply>
<ci>norm</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>O_CaL</ci>
</apply>
<apply>
<plus/>
<apply>
<minus/>
<apply>
<divide/>
<apply>
<times/>
<ci>alpha_3</ci>
<ci>C3</ci>
</apply>
<ci>norm</ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<apply>
<plus/>
<ci>beta_3</ci>
<ci>psi_f</ci>
<ci>psi_s</ci>
<ci>theta</ci>
</apply>
<ci>O_CaL</ci>
</apply>
<ci>norm</ci>
</apply>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci>xi_f</ci>
<ci>IVf</ci>
</apply>
<ci>norm</ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci>xi_s</ci>
<ci>IVs</ci>
</apply>
<ci>norm</ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci>delta</ci>
<ci>ICa</ci>
</apply>
<ci>norm</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>ICa</ci>
</apply>
<apply>
<plus/>
<apply>
<minus/>
<apply>
<plus/>
<apply>
<divide/>
<apply>
<times/>
<ci>theta</ci>
<ci>O_CaL</ci>
</apply>
<ci>norm</ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci>alpha_3</ci>
<ci>C3Ca</ci>
</apply>
<ci>norm</ci>
</apply>
</apply>
<apply>
<divide/>
<apply>
<times/>
<apply>
<plus/>
<ci>beta_3</ci>
<ci>psi_f</ci>
<ci>psi_s</ci>
<ci>delta</ci>
</apply>
<ci>ICa</ci>
</apply>
<ci>norm</ci>
</apply>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci>xi_f</ci>
<ci>IVfCa</ci>
</apply>
<ci>norm</ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci>xi_s</ci>
<ci>IVsCa</ci>
</apply>
<ci>norm</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>IVs</ci>
</apply>
<apply>
<plus/>
<apply>
<minus/>
<apply>
<plus/>
<apply>
<divide/>
<apply>
<times/>
<ci>phi_s</ci>
<ci>C3</ci>
</apply>
<ci>norm</ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci>psi_s</ci>
<ci>O_CaL</ci>
</apply>
<ci>norm</ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci>omega_fs</ci>
<ci>IVf</ci>
</apply>
<ci>norm</ci>
</apply>
</apply>
<apply>
<divide/>
<apply>
<times/>
<apply>
<plus/>
<ci>omega_s</ci>
<ci>xi_s</ci>
<ci>omega_sf</ci>
<ci>theta</ci>
</apply>
<ci>IVs</ci>
</apply>
<ci>norm</ci>
</apply>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci>delta</ci>
<ci>IVsCa</ci>
</apply>
<ci>norm</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>IVf</ci>
</apply>
<apply>
<plus/>
<apply>
<minus/>
<apply>
<plus/>
<apply>
<divide/>
<apply>
<times/>
<ci>phi_f</ci>
<ci>C3</ci>
</apply>
<ci>norm</ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci>psi_f</ci>
<ci>O_CaL</ci>
</apply>
<ci>norm</ci>
</apply>
</apply>
<apply>
<divide/>
<apply>
<times/>
<apply>
<plus/>
<ci>omega_f</ci>
<ci>xi_f</ci>
<ci>omega_fs</ci>
<ci>theta</ci>
</apply>
<ci>IVf</ci>
</apply>
<ci>norm</ci>
</apply>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci>omega_sf</ci>
<ci>IVs</ci>
</apply>
<ci>norm</ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci>delta</ci>
<ci>IVfCa</ci>
</apply>
<ci>norm</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>IVsCa</ci>
</apply>
<apply>
<minus/>
<apply>
<plus/>
<apply>
<divide/>
<apply>
<times/>
<ci>theta</ci>
<ci>IVs</ci>
</apply>
<ci>norm</ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci>phi_s</ci>
<ci>C3Ca</ci>
</apply>
<ci>norm</ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci>psi_s</ci>
<ci>ICa</ci>
</apply>
<ci>norm</ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci>omega_fs</ci>
<ci>IVfCa</ci>
</apply>
<ci>norm</ci>
</apply>
</apply>
<apply>
<divide/>
<apply>
<times/>
<apply>
<plus/>
<ci>omega_s</ci>
<ci>xi_s</ci>
<ci>omega_sf</ci>
<ci>delta</ci>
</apply>
<ci>IVsCa</ci>
</apply>
<ci>norm</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>IVfCa</ci>
</apply>
<apply>
<plus/>
<apply>
<minus/>
<apply>
<plus/>
<apply>
<divide/>
<apply>
<times/>
<ci>theta</ci>
<ci>IVf</ci>
</apply>
<ci>norm</ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci>phi_f</ci>
<ci>C3Ca</ci>
</apply>
<ci>norm</ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci>psi_f</ci>
<ci>ICa</ci>
</apply>
<ci>norm</ci>
</apply>
</apply>
<apply>
<divide/>
<apply>
<times/>
<apply>
<plus/>
<ci>omega_f</ci>
<ci>xi_f</ci>
<ci>omega_fs</ci>
<ci>delta</ci>
</apply>
<ci>IVfCa</ci>
</apply>
<ci>norm</ci>
</apply>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci>omega_sf</ci>
<ci>IVsCa</ci>
</apply>
<ci>norm</ci>
</apply>
</apply>
</apply>
</math>
</component>
<group>
<relationship_ref relationship="encapsulation"/>
<component_ref component="ICaL_channel_states">
<component_ref component="temperature_factor"/>
</component_ref>
</group>
<connection>
<map_components component_1="ICaL_channel_states" component_2="temperature_factor"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="T0" variable_2="T0"/>
<map_variables variable_1="Q10Ca" variable_2="Q10"/>
<map_variables variable_1="phi" variable_2="phi"/>
</connection>
</model>